Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on: May 08,2024 8

Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on:May 08,2024 8

Researchers identify new target for rheumatoid arthritis

by Hospital for Special SurgeryCo-senior author and Program Director Carl Blobel, M.D., Ph.D., works with collaborator Lionel Ivashkiv, M.D., in the Arthritis and Tissue Degeneration Program lab

Updated on: March 24,2024 15

Researchers identify new target for rheumatoid arthritis

by Hospital for Special SurgeryCo-senior author and Program Director Carl Blobel, M.D., Ph.D., works with collaborator Lionel Ivashkiv, M.D., in the Arthritis and Tissue Degeneration Program lab

Updated on:March 24,2024 15

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on: June 18,2024 8

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on:June 18,2024 8

Chemical stimuli can support growing of stable cartilage cells

by Umea UniversityRho-kinase inhibition cause disappearance of cellular adhesion sites. The colors of the figure shows the staining for actin stress fibers (red), adhesion plaques-related vinculi

Updated on: May 08,2024 8

Chemical stimuli can support growing of stable cartilage cells

by Umea UniversityRho-kinase inhibition cause disappearance of cellular adhesion sites. The colors of the figure shows the staining for actin stress fibers (red), adhesion plaques-related vinculi

Updated on:May 08,2024 8

Potential biomarkers identified for neuropsychiatric symptoms of lupus

by Laurie Fickman,University of HoustonCredit: CC0 Public DomainA globally renowned expert in autoimmune diseases and systemic lupus erythematosus (SLE) at the University of Houston has identifi

Updated on: June 06,2024 3

Potential biomarkers identified for neuropsychiatric symptoms of lupus

by Laurie Fickman,University of HoustonCredit: CC0 Public DomainA globally renowned expert in autoimmune diseases and systemic lupus erythematosus (SLE) at the University of Houston has identifi

Updated on:June 06,2024 3

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on: May 08,2024 4

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on:May 08,2024 4

Enhanced stability of tristetraprolin found to promote bone health and reduce frailty

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study used a novel transgenic mouse model (TTP knock-in—TTPKI) that has a moderate elevation

Updated on: March 27,2024 0

Enhanced stability of tristetraprolin found to promote bone health and reduce frailty

by International Association for Dental, Oral, and Craniofacial ResearchCredit: Unsplash/CC0 Public DomainA study used a novel transgenic mouse model (TTP knock-in—TTPKI) that has a moderate elevation

Updated on:March 27,2024 0

Investigating healthy lifestyle and mortality in osteoarthritis

by European Alliance of Associations for Rheumatology (EULAR)Credit: CC0 Public DomainHealthy lifestyles are thought to reduce mortality in the general population, but it is not known whether the same

Updated on: April 17,2024 20

Investigating healthy lifestyle and mortality in osteoarthritis

by European Alliance of Associations for Rheumatology (EULAR)Credit: CC0 Public DomainHealthy lifestyles are thought to reduce mortality in the general population, but it is not known whether the same

Updated on:April 17,2024 20

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on: May 06,2024 11

A messenger substance considered to be inflammatory can alleviate asthma symptoms

by Friedrich–Alexander University Erlangen–NurnbergIntranasal rIL-3 application during challenge induces Treg cells. (A) Experimental design for lung ILC2 skewing. (B) After 5 days of in vitro IL

Updated on:May 06,2024 11

T cells alone are sufficient to establish and maintain HIV infection in the brain

by University of North Carolina Health CareScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by Unive

Updated on: May 07,2024 19

T cells alone are sufficient to establish and maintain HIV infection in the brain

by University of North Carolina Health CareScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by Unive

Updated on:May 07,2024 19

Increased use of partial knee replacement could save the NHS £30 million per year

by University of OxfordCredit: NDORMSNew research from a randomised clinical trial published today inThe Lancetand funded by the National Institute for Health Research (NIHR) shows th

Updated on: March 28,2024 17

Increased use of partial knee replacement could save the NHS £30 million per year

by University of OxfordCredit: NDORMSNew research from a randomised clinical trial published today inThe Lancetand funded by the National Institute for Health Research (NIHR) shows th

Updated on:March 28,2024 17

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on: May 05,2024 19

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on:May 05,2024 19