CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on: April 09,2024

CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

Updated on:April 09,2024

Salivary gland ultrasonography improves Sjogren's diagnosis

The addition of salivary-gland ultrasonography to American-European Consensus Group classification criteria improves the accuracy of diagnosis of primary Sjögren's syndrome, according to a study p

Updated on: March 24,2024

Salivary gland ultrasonography improves Sjogren's diagnosis

The addition of salivary-gland ultrasonography to American-European Consensus Group classification criteria improves the accuracy of diagnosis of primary Sjögren's syndrome, according to a study p

Updated on:March 24,2024

Poverty tied to worse functional status in rheumatoid arthritis

(HealthDay)—Worse functional status and increased probability of functional decline are seen for patients with rheumatoid arthritis (RA) with lower socioeconomic status (SES), according to a study pub

Updated on: June 01,2024

Poverty tied to worse functional status in rheumatoid arthritis

(HealthDay)—Worse functional status and increased probability of functional decline are seen for patients with rheumatoid arthritis (RA) with lower socioeconomic status (SES), according to a study pub

Updated on:June 01,2024

CRISPR study reveals new immune system regulators

by Wellcome Trust Sanger InstituteCRISPR-associated protein Cas9 (white) from Staphylococcus aureus based on Protein Database ID 5AXW. Credit: Thomas Splettstoesser (Wikipedia, CC BY-SA 4.0)Scien

Updated on: April 13,2024

CRISPR study reveals new immune system regulators

by Wellcome Trust Sanger InstituteCRISPR-associated protein Cas9 (white) from Staphylococcus aureus based on Protein Database ID 5AXW. Credit: Thomas Splettstoesser (Wikipedia, CC BY-SA 4.0)Scien

Updated on:April 13,2024

Vitamin D shows no impact on interferon response in SLE

(HealthDay)—For patients with systemic lupus erythematosus (SLE), vitamin D3supplementation does not affect interferon (IFN) signature, according to a study published in the July issue ofA

Updated on: April 08,2024

Vitamin D shows no impact on interferon response in SLE

(HealthDay)—For patients with systemic lupus erythematosus (SLE), vitamin D3supplementation does not affect interferon (IFN) signature, according to a study published in the July issue ofA

Updated on:April 08,2024

Early signs of arthritis can be found in the mouth

by University of AdelaideThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterA common gum disease may indicate a person's risk of developing rheumatoid arthr

Updated on: April 20,2024

Early signs of arthritis can be found in the mouth

by University of AdelaideThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterA common gum disease may indicate a person's risk of developing rheumatoid arthr

Updated on:April 20,2024

How COVID-19 triggers massive inflammation

by Children's Hospital BostonSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHA study led by researchers at Boston Ch

Updated on: April 13,2024

How COVID-19 triggers massive inflammation

by Children's Hospital BostonSARS-CoV-2 (shown here in an electron microscopy image). Credit: National Institute of Allergy and Infectious Diseases, NIHA study led by researchers at Boston Ch

Updated on:April 13,2024

Gene variant tied to risk for interstitial lung disease in RA

(HealthDay)—For patients with rheumatoid arthritis (RA), theMUC5Bvariant is associated with an increased risk for RA-associated interstitial lung disease (ILD), according to a study publis

Updated on: June 26,2024

Gene variant tied to risk for interstitial lung disease in RA

(HealthDay)—For patients with rheumatoid arthritis (RA), theMUC5Bvariant is associated with an increased risk for RA-associated interstitial lung disease (ILD), according to a study publis

Updated on:June 26,2024

Pain and fatigue in rheumatoid arthritis tied to sitting and standing time

For patients with rheumatoid arthritis (RA), pain and fatigue may both cause and be caused by more sitting time and less standing time, according to a study published in the October issue ofRheu

Updated on: June 17,2024

Pain and fatigue in rheumatoid arthritis tied to sitting and standing time

For patients with rheumatoid arthritis (RA), pain and fatigue may both cause and be caused by more sitting time and less standing time, according to a study published in the October issue ofRheu

Updated on:June 17,2024

COVID-19: The older you are, the more antibodies you have

by University of MontrealA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDWith the emergence of SARS-CoV-2 variants worldwide, the pandemic's spread is accelerat

Updated on: April 10,2024

COVID-19: The older you are, the more antibodies you have

by University of MontrealA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDWith the emergence of SARS-CoV-2 variants worldwide, the pandemic's spread is accelerat

Updated on:April 10,2024

Patient-driven discovery reveals potential target for autoimmune diseases

by Isabella Backman,Yale UniversityModel summarizing the function of PI3Kγ in antibody responses. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01890-1A medical mystery ser

Updated on: July 17,2024

Patient-driven discovery reveals potential target for autoimmune diseases

by Isabella Backman,Yale UniversityModel summarizing the function of PI3Kγ in antibody responses. Credit:Nature Immunology(2024). DOI: 10.1038/s41590-024-01890-1A medical mystery ser

Updated on:July 17,2024

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on: April 20,2024

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on:April 20,2024