Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on: May 08,2024 8

Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on:May 08,2024 8

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025 0

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025 0

Investigating healthy lifestyle and mortality in osteoarthritis

by European Alliance of Associations for Rheumatology (EULAR)Credit: CC0 Public DomainHealthy lifestyles are thought to reduce mortality in the general population, but it is not known whether the same

Updated on: April 17,2024 20

Investigating healthy lifestyle and mortality in osteoarthritis

by European Alliance of Associations for Rheumatology (EULAR)Credit: CC0 Public DomainHealthy lifestyles are thought to reduce mortality in the general population, but it is not known whether the same

Updated on:April 17,2024 20

Early and intensive treatment of rheumatoid arthritis reduces fatigue

by European League Against RheumatismCredit: CC0 Public DomainDisease-related, profound fatigue impairs the quality of life of many people with rheumatic and musculoskeletal diseases. A Belgian s

Updated on: June 26,2024 5

Early and intensive treatment of rheumatoid arthritis reduces fatigue

by European League Against RheumatismCredit: CC0 Public DomainDisease-related, profound fatigue impairs the quality of life of many people with rheumatic and musculoskeletal diseases. A Belgian s

Updated on:June 26,2024 5

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on: March 24,2024 14

Epigenetics alters genes in rheumatoid arthritis

by University of California - San DiegoIn this artist's rendering, a DNA molecule is methylated on both strands at the center cytosine. DNA methylation plays an important role in epigenetic g

Updated on:March 24,2024 14

Experiments in infant mice suggest new way to prevent spread of flu in people

JANUARY 11, 2024byNYU Langone HealthCredit: Andrea Piacquadio from PexelsScientists have long known that some viruses and bacteria begin infections by latching first onto sugar molecules on the

Updated on: March 30,2024 6

Experiments in infant mice suggest new way to prevent spread of flu in people

JANUARY 11, 2024byNYU Langone HealthCredit: Andrea Piacquadio from PexelsScientists have long known that some viruses and bacteria begin infections by latching first onto sugar molecules on the

Updated on:March 30,2024 6

Innovative software improves chronic rheumatic disease care

(HealthDay)—For patients with chronic rheumatic disease, innovative software that aggregates, stores, and displays information can improve quality of care, according to research published online Nov.

Updated on: April 08,2024 15

Innovative software improves chronic rheumatic disease care

(HealthDay)—For patients with chronic rheumatic disease, innovative software that aggregates, stores, and displays information can improve quality of care, according to research published online Nov.

Updated on:April 08,2024 15

COVID-19's deadliness for men reveals why researchers should have been studying immune system sex differences years ago

by Adam Moeser,The ConversationCredit: CC0 Public DomainWhen it comes to surviving critical cases of COVID-19, it appears that men draw the short straw.Initial reports from China revealed the ea

Updated on: April 10,2024 12

COVID-19's deadliness for men reveals why researchers should have been studying immune system sex differences years ago

by Adam Moeser,The ConversationCredit: CC0 Public DomainWhen it comes to surviving critical cases of COVID-19, it appears that men draw the short straw.Initial reports from China revealed the ea

Updated on:April 10,2024 12

First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on: April 09,2024 19

First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on:April 09,2024 19

T cells alone are sufficient to establish and maintain HIV infection in the brain

by University of North Carolina Health CareScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by Unive

Updated on: May 07,2024 19

T cells alone are sufficient to establish and maintain HIV infection in the brain

by University of North Carolina Health CareScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDA new study by Unive

Updated on:May 07,2024 19

Increased use of partial knee replacement could save the NHS £30 million per year

by University of OxfordCredit: NDORMSNew research from a randomised clinical trial published today inThe Lancetand funded by the National Institute for Health Research (NIHR) shows th

Updated on: March 28,2024 17

Increased use of partial knee replacement could save the NHS £30 million per year

by University of OxfordCredit: NDORMSNew research from a randomised clinical trial published today inThe Lancetand funded by the National Institute for Health Research (NIHR) shows th

Updated on:March 28,2024 17

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on: May 05,2024 19

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on:May 05,2024 19