Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on: September 04,2024

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on:September 04,2024

Mood disorders common with rheumatoid arthritis

(HealthDay)—Depression and anxiety are common in patients with rheumatoid arthritis (RA), according to a study published online Jan. 6 in theInternational Journal of Rheumatic Diseases.Wanruchad

Updated on: July 02,2024

Mood disorders common with rheumatoid arthritis

(HealthDay)—Depression and anxiety are common in patients with rheumatoid arthritis (RA), according to a study published online Jan. 6 in theInternational Journal of Rheumatic Diseases.Wanruchad

Updated on:July 02,2024

Unique immune response found in patients who experience inflammatory arthritis as side effect of cancer therapies

by Brigham and Women's HospitalMultiplexed immunofluorescence of synovial tissue. Multiplexed immunofluorescence images showing an example of a Ki67+PD-1+synovial CD8 T cell (white arro

Updated on: July 03,2024

Unique immune response found in patients who experience inflammatory arthritis as side effect of cancer therapies

by Brigham and Women's HospitalMultiplexed immunofluorescence of synovial tissue. Multiplexed immunofluorescence images showing an example of a Ki67+PD-1+synovial CD8 T cell (white arro

Updated on:July 03,2024

T-cells shown to infiltrate brain, cause respiratory distress in condition affecting the immunocompromised

by Liz Ahlberg Touchstone |,University of Illinois at Urbana-ChampaignPulmonary dysfunction and mortality under the C-IRIS condition.ASchematic representation of the experiments and

Updated on: May 05,2024

T-cells shown to infiltrate brain, cause respiratory distress in condition affecting the immunocompromised

by Liz Ahlberg Touchstone |,University of Illinois at Urbana-ChampaignPulmonary dysfunction and mortality under the C-IRIS condition.ASchematic representation of the experiments and

Updated on:May 05,2024

Study examines care for knee replacement patients at physical therapy facilities

by WileyCredit: CC0 Public DomainIn an analysis of 112 records from 30 physical therapy (PT) sites regarding care for patients who had undergone total knee replacement (TKR) surgery, investigator

Updated on: April 17,2024

Study examines care for knee replacement patients at physical therapy facilities

by WileyCredit: CC0 Public DomainIn an analysis of 112 records from 30 physical therapy (PT) sites regarding care for patients who had undergone total knee replacement (TKR) surgery, investigator

Updated on:April 17,2024

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on: April 20,2024

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Updated on:April 20,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on: June 17,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on:June 17,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on: May 30,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on:May 30,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on: April 13,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on:April 13,2024

Breast-feeding might reduce moms' odds of rheumatoid arthritis

Study in China finds risk cut nearly in half after nursing.(HealthDay)—Women who breast-feed may have a lower risk of developing rheumatoid arthritis later in life, new research suggests.Researchers a

Updated on: March 24,2024

Breast-feeding might reduce moms' odds of rheumatoid arthritis

Study in China finds risk cut nearly in half after nursing.(HealthDay)—Women who breast-feed may have a lower risk of developing rheumatoid arthritis later in life, new research suggests.Researchers a

Updated on:March 24,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on: May 05,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on:May 05,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024