A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on: March 25,2024 20

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on:March 25,2024 20

Nasopharyngeal carcinoma treatment using exosomes derived from γδ-T cells synergized with radiotherapy

by The University of Hong KongExos induce apoptosis of NPC tumor cells through death receptor ligation. NPC43 or C666-1 cells were treated with PBS, ultracentrifuged pellets isolated from FBS–exo

Updated on: May 07,2024 16

Nasopharyngeal carcinoma treatment using exosomes derived from γδ-T cells synergized with radiotherapy

by The University of Hong KongExos induce apoptosis of NPC tumor cells through death receptor ligation. NPC43 or C666-1 cells were treated with PBS, ultracentrifuged pellets isolated from FBS–exo

Updated on:May 07,2024 16

Biomarkers may ID rheumatoid arthritis patients with and without active disease

Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) values may differentiate between rheumatoid arthritis (RA) patients with and without active disease, according to a systemat

Updated on: May 29,2024 8

Biomarkers may ID rheumatoid arthritis patients with and without active disease

Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) values may differentiate between rheumatoid arthritis (RA) patients with and without active disease, according to a systemat

Updated on:May 29,2024 8

Omega-3s could boost immunotherapy's cancer-fighting power

by Experimental BiologyOmega-3 supplementation improves the efficacy of immunotherapy in subcutaneous murine MB49 bladder cancer tumors. Credit: Abigail Kelly, Beth Israel Deaconess Medical Center/Har

Updated on: April 20,2024 20

Omega-3s could boost immunotherapy's cancer-fighting power

by Experimental BiologyOmega-3 supplementation improves the efficacy of immunotherapy in subcutaneous murine MB49 bladder cancer tumors. Credit: Abigail Kelly, Beth Israel Deaconess Medical Center/Har

Updated on:April 20,2024 20

A new cause of osteoarthritis identified by research on a rare disease

by University of LiverpoolMicro CT scan of the head of a femur (thigh bone) showing the presence of sharp HDMPs on the surface of the bone." Credit: University of LiverpoolA new mechanism of

Updated on: May 08,2024 3

A new cause of osteoarthritis identified by research on a rare disease

by University of LiverpoolMicro CT scan of the head of a femur (thigh bone) showing the presence of sharp HDMPs on the surface of the bone." Credit: University of LiverpoolA new mechanism of

Updated on:May 08,2024 3

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024 5

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024 5

Swimming short fibrous nasal drops achieve intraventricular administration

byScience China PressInspired by swimming fish and the microstructure of the nasal cavity, short-swimming fibrous nasal drops with the ability to transport drugs along the nasal mucosa were inno

Updated on: April 28,2024 0

Swimming short fibrous nasal drops achieve intraventricular administration

byScience China PressInspired by swimming fish and the microstructure of the nasal cavity, short-swimming fibrous nasal drops with the ability to transport drugs along the nasal mucosa were inno

Updated on:April 28,2024 0

Tofacitinib ups rheumatoid arthritis treatment response

The addition of tofacitinib to rheumatoid arthritis treatment regimens improves patient response to non-biologic disease-modifying antirheumatic drugs, according to a study published in the Aug. 20 is

Updated on: April 08,2024 20

Tofacitinib ups rheumatoid arthritis treatment response

The addition of tofacitinib to rheumatoid arthritis treatment regimens improves patient response to non-biologic disease-modifying antirheumatic drugs, according to a study published in the Aug. 20 is

Updated on:April 08,2024 20

New juvenile idiopathic arthritis guideline emphasizes disease-modifying treatments

by American College of RheumatologyCredit: CC0 Public DomainThe American College of Rheumatology (ACR) will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Co

Updated on: May 08,2024 8

New juvenile idiopathic arthritis guideline emphasizes disease-modifying treatments

by American College of RheumatologyCredit: CC0 Public DomainThe American College of Rheumatology (ACR) will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Co

Updated on:May 08,2024 8

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p

Updated on: April 09,2024 11

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p

Updated on:April 09,2024 11

An existing drug may change tumor-associated macrophages back to cancer fighters

by Jeff Hansen,University of Alabama at BirminghamCredit: Unsplash/CC0 Public DomainA form of cell communication called hedgehog signaling is vital for embryonic development in mammals. Bu

Updated on: March 26,2024 16

An existing drug may change tumor-associated macrophages back to cancer fighters

by Jeff Hansen,University of Alabama at BirminghamCredit: Unsplash/CC0 Public DomainA form of cell communication called hedgehog signaling is vital for embryonic development in mammals. Bu

Updated on:March 26,2024 16

A new method measures the immune cell response within minutes

by Universitaet TübingenThe new method identifies structural changes in the integrins, certain molecules expressed on the cell surface of the T cells, and thus detects whether the T lymphocytes a

Updated on: March 26,2024 13

A new method measures the immune cell response within minutes

by Universitaet TübingenThe new method identifies structural changes in the integrins, certain molecules expressed on the cell surface of the T cells, and thus detects whether the T lymphocytes a

Updated on:March 26,2024 13