Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

How changing gut microbiota can affect lupus disease activity in mice

by The Ohio State UniversityFigure 1. NZM2410 colonized with SFB exhibit intensified kidney disease with elevated immune-complex deposition. 10-week old mice were oral gavaged with fecal matter f

Updated on: June 20,2024

How changing gut microbiota can affect lupus disease activity in mice

by The Ohio State UniversityFigure 1. NZM2410 colonized with SFB exhibit intensified kidney disease with elevated immune-complex deposition. 10-week old mice were oral gavaged with fecal matter f

Updated on:June 20,2024

Early combined treatment with biologic and conventional DMARDs could be effective for polyarticular juvenile arthritis

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that patients sta

Updated on: March 28,2024

Early combined treatment with biologic and conventional DMARDs could be effective for polyarticular juvenile arthritis

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, found that patients sta

Updated on:March 28,2024

Exercise training improves cardiac parameters in lupus

(HealthDay) -- For inactive patients with systemic lupus erythematosus (SLE), a three-month exercise training program is associated with improved chronotropic reserve and heart rate recovery, accordin

Updated on: March 24,2024

Exercise training improves cardiac parameters in lupus

(HealthDay) -- For inactive patients with systemic lupus erythematosus (SLE), a three-month exercise training program is associated with improved chronotropic reserve and heart rate recovery, accordin

Updated on:March 24,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on: April 10,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on:April 10,2024

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on: June 01,2024

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on:June 01,2024

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on: May 08,2024

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on:May 08,2024

New therapy shown to be effective in women with fibromyalgia and depression

by Universitat Oberta de CatalunyaCONSORT Diagram of participants flow in this randomized controlled trial. Credit:International Journal of Clinical and Health Psychology(2022). DOI: 10.10

Updated on: June 15,2024

New therapy shown to be effective in women with fibromyalgia and depression

by Universitat Oberta de CatalunyaCONSORT Diagram of participants flow in this randomized controlled trial. Credit:International Journal of Clinical and Health Psychology(2022). DOI: 10.10

Updated on:June 15,2024

β-damascone: Using the aroma component of rose fragrance as a novel immunomodulator

by Tokyo University of ScienceOveractivation of dendritic cells (DCs), components of the immune system, can cause immune diseases. β-damascone, a constituent of rose fragrance was identified as a

Updated on: May 07,2024

β-damascone: Using the aroma component of rose fragrance as a novel immunomodulator

by Tokyo University of ScienceOveractivation of dendritic cells (DCs), components of the immune system, can cause immune diseases. β-damascone, a constituent of rose fragrance was identified as a

Updated on:May 07,2024

Back pain link to 24-hour body clock revealed

by University of ManchesterCredit: University of ManchesterNew research by University of Manchester scientists has for the first time shown that our spinal discs have 24-hour body clocks which wh

Updated on: March 24,2024

Back pain link to 24-hour body clock revealed

by University of ManchesterCredit: University of ManchesterNew research by University of Manchester scientists has for the first time shown that our spinal discs have 24-hour body clocks which wh

Updated on:March 24,2024

Preclinical study of COVID-19 vaccine candidate shows potent T-cell responses

by University of Alabama at BirminghamCredit: University of Alabama at BirminghamPreclinical studies of a COVID-19 vaccine candidate at the University of Alabama at Birmingham show positive resul

Updated on: April 10,2024

Preclinical study of COVID-19 vaccine candidate shows potent T-cell responses

by University of Alabama at BirminghamCredit: University of Alabama at BirminghamPreclinical studies of a COVID-19 vaccine candidate at the University of Alabama at Birmingham show positive resul

Updated on:April 10,2024