Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

A mathematical model that predicts how severe hay fever season will be

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainAn international team of researchers has developed a mathematical model for predicting how bad an upcoming hay fever season will be. In th

Updated on: May 07,2024

A mathematical model that predicts how severe hay fever season will be

by Bob Yirka , Medical XpressCredit: Pixabay/CC0 Public DomainAn international team of researchers has developed a mathematical model for predicting how bad an upcoming hay fever season will be. In th

Updated on:May 07,2024

A new plant-based system for the mass production of allergens for immunotherapy

by University of TsukubaCredit: University of TsukubaAllergies can significantly affect health and quality of life. While allergen immunotherapy provides long-lasting therapeutic relief to people

Updated on: March 26,2024

A new plant-based system for the mass production of allergens for immunotherapy

by University of TsukubaCredit: University of TsukubaAllergies can significantly affect health and quality of life. While allergen immunotherapy provides long-lasting therapeutic relief to people

Updated on:March 26,2024

A new pathway to 'reprogram' killer cells

by University of BernNK cells (brown) patrolling between cells of a healthy human lymph node. Credit: Institute of Pathology, University of BernThe so-called natural killer (NK) cells are cells o

Updated on: May 08,2024

A new pathway to 'reprogram' killer cells

by University of BernNK cells (brown) patrolling between cells of a healthy human lymph node. Credit: Institute of Pathology, University of BernThe so-called natural killer (NK) cells are cells o

Updated on:May 08,2024

A safer treatment path for high-risk children to overcome food allergies

by University of British ColumbiaCredit: Unsplash/CC0 Public DomainNew research from the University of British Columbia reveals a safe path to overcoming food allergies for older children and oth

Updated on: March 07,2024

A safer treatment path for high-risk children to overcome food allergies

by University of British ColumbiaCredit: Unsplash/CC0 Public DomainNew research from the University of British Columbia reveals a safe path to overcoming food allergies for older children and oth

Updated on:March 07,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on: April 09,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on:April 09,2024

Biomarkers may ID rheumatoid arthritis patients with and without active disease

Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) values may differentiate between rheumatoid arthritis (RA) patients with and without active disease, according to a systemat

Updated on: May 29,2024

Biomarkers may ID rheumatoid arthritis patients with and without active disease

Neutrophil-to-lymphocyte ratio (NLR) and platelet-to-lymphocyte ratio (PLR) values may differentiate between rheumatoid arthritis (RA) patients with and without active disease, according to a systemat

Updated on:May 29,2024

New study indicates why children are likelier to develop food allergies

by La Jolla Institute for Allergy and ImmunologyA study by LJI researchers identified a T cell population that renders normal food non-allergenic. Credit: La Jolla Institute for Allergy and Immun

Updated on: May 08,2024

New study indicates why children are likelier to develop food allergies

by La Jolla Institute for Allergy and ImmunologyA study by LJI researchers identified a T cell population that renders normal food non-allergenic. Credit: La Jolla Institute for Allergy and Immun

Updated on:May 08,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on: April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on:April 09,2024

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role

Updated on: June 17,2024

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role

Updated on:June 17,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on: April 08,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on:April 08,2024