Research into autoimmune liver condition suggests unique cell movements may drive disease

by University of BirminghamCD8+T cell internalization into BEC is a consistent event in PBC patients with ongoing disease. a) Representative fluorescence image of liver core biopsy, taken f

Updated on: March 07,2024

Research into autoimmune liver condition suggests unique cell movements may drive disease

by University of BirminghamCD8+T cell internalization into BEC is a consistent event in PBC patients with ongoing disease. a) Representative fluorescence image of liver core biopsy, taken f

Updated on:March 07,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on: July 11,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on:July 11,2024

New insights on B cells: Researchers explore building better antibodies and curbing autoimmune diseases

by Nancy Fliesler,Harvard Medical SchoolGb3 drives affinity and diversity of antibody responses and protects against viral infection. Credit:Science(2024). DOI: 10.1126/science.adg05

Updated on: April 28,2024

New insights on B cells: Researchers explore building better antibodies and curbing autoimmune diseases

by Nancy Fliesler,Harvard Medical SchoolGb3 drives affinity and diversity of antibody responses and protects against viral infection. Credit:Science(2024). DOI: 10.1126/science.adg05

Updated on:April 28,2024

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on: April 24,2024

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on:April 24,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024

Mood disorders common with rheumatoid arthritis

(HealthDay)—Depression and anxiety are common in patients with rheumatoid arthritis (RA), according to a study published online Jan. 6 in theInternational Journal of Rheumatic Diseases.Wanruchad

Updated on: July 02,2024

Mood disorders common with rheumatoid arthritis

(HealthDay)—Depression and anxiety are common in patients with rheumatoid arthritis (RA), according to a study published online Jan. 6 in theInternational Journal of Rheumatic Diseases.Wanruchad

Updated on:July 02,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on: March 27,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on:March 27,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on: April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on:April 09,2024

Rheumatoid arthritis linked to peripheral artery disease

by Lori SolomonThere may be an association between rheumatoid arthritis (RA) and peripheral artery disease (PAD), according to a review published online Nov. 30 inRheumatology International.Tays

Updated on: June 26,2024

Rheumatoid arthritis linked to peripheral artery disease

by Lori SolomonThere may be an association between rheumatoid arthritis (RA) and peripheral artery disease (PAD), according to a review published online Nov. 30 inRheumatology International.Tays

Updated on:June 26,2024

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role

Updated on: June 17,2024

How intravenous immunoglobulin antibodies resolve joint inflammation in rheumatoid arthritis

by Friedrich–Alexander University Erlangen–NurnbergGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.02.019Immunoglobulin G antibodies (IgB) play an important role

Updated on:June 17,2024

New research shows early Maori probably suffered from gout

by University of Otago(Medical Xpress)—Discoveries of early Māori skeletal remains showing tell-tale signs of gout have been corroborated by new evidence that dispels the myth that the disease wa

Updated on: March 24,2024

New research shows early Maori probably suffered from gout

by University of Otago(Medical Xpress)—Discoveries of early Māori skeletal remains showing tell-tale signs of gout have been corroborated by new evidence that dispels the myth that the disease wa

Updated on:March 24,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on: April 22,2024

SARS-CoV-2 curtails immune response in the gut

by European Molecular Biology LaboratoryThe researchers were able to monitor the virus's growth in organoids derived from human intestinal cells. Pink and red show areas of SARS-CoV-2 infecti

Updated on:April 22,2024