Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024

Omega-3s could boost immunotherapy's cancer-fighting power

by Experimental BiologyOmega-3 supplementation improves the efficacy of immunotherapy in subcutaneous murine MB49 bladder cancer tumors. Credit: Abigail Kelly, Beth Israel Deaconess Medical Center/Har

Updated on: April 20,2024

Omega-3s could boost immunotherapy's cancer-fighting power

by Experimental BiologyOmega-3 supplementation improves the efficacy of immunotherapy in subcutaneous murine MB49 bladder cancer tumors. Credit: Abigail Kelly, Beth Israel Deaconess Medical Center/Har

Updated on:April 20,2024

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on: May 05,2024

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on:May 05,2024

CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

by Impact Journals LLC(A) Immunohistochemistry (IHC) staining of testis (positive control). (B) IHC staining of colonic adenocarcinoma. (C) IHC stating of Normal colonic mucosa (negative control). Pur

Updated on: April 08,2024

CABYR-a/b and CABYR-c hold promise as targets for specific immunotherapy

by Impact Journals LLC(A) Immunohistochemistry (IHC) staining of testis (positive control). (B) IHC staining of colonic adenocarcinoma. (C) IHC stating of Normal colonic mucosa (negative control). Pur

Updated on:April 08,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024

Quality of cartilage repair tissue can also be determined without a surgery

by Medical University of ViennaA team at the MedUni Vienna, headed by Sebastian Apprich of the University Department of Radiodiagnostics at the High-Field Magnetic Resonance Centre of Excellence, has

Updated on: March 24,2024

Quality of cartilage repair tissue can also be determined without a surgery

by Medical University of ViennaA team at the MedUni Vienna, headed by Sebastian Apprich of the University Department of Radiodiagnostics at the High-Field Magnetic Resonance Centre of Excellence, has

Updated on:March 24,2024

New therapy shown to be effective in women with fibromyalgia and depression

by Universitat Oberta de CatalunyaCONSORT Diagram of participants flow in this randomized controlled trial. Credit:International Journal of Clinical and Health Psychology(2022). DOI: 10.10

Updated on: June 15,2024

New therapy shown to be effective in women with fibromyalgia and depression

by Universitat Oberta de CatalunyaCONSORT Diagram of participants flow in this randomized controlled trial. Credit:International Journal of Clinical and Health Psychology(2022). DOI: 10.10

Updated on:June 15,2024

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on: March 07,2024

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on:March 07,2024

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on: April 20,2024

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on:April 20,2024

Back pain link to 24-hour body clock revealed

by University of ManchesterCredit: University of ManchesterNew research by University of Manchester scientists has for the first time shown that our spinal discs have 24-hour body clocks which wh

Updated on: March 24,2024

Back pain link to 24-hour body clock revealed

by University of ManchesterCredit: University of ManchesterNew research by University of Manchester scientists has for the first time shown that our spinal discs have 24-hour body clocks which wh

Updated on:March 24,2024

New study indicates why children are likelier to develop food allergies

by La Jolla Institute for Allergy and ImmunologyA study by LJI researchers identified a T cell population that renders normal food non-allergenic. Credit: La Jolla Institute for Allergy and Immun

Updated on: May 08,2024

New study indicates why children are likelier to develop food allergies

by La Jolla Institute for Allergy and ImmunologyA study by LJI researchers identified a T cell population that renders normal food non-allergenic. Credit: La Jolla Institute for Allergy and Immun

Updated on:May 08,2024

Tracking down the genetic causes of lupus to personalize treatment

by University of California - BerkeleyMany autoimmune diseases, including lupus, have been linked to problems with the toll-like receptors (TLR) on immune cells, in particular the TLR7 and TLR8 r

Updated on: May 30,2024

Tracking down the genetic causes of lupus to personalize treatment

by University of California - BerkeleyMany autoimmune diseases, including lupus, have been linked to problems with the toll-like receptors (TLR) on immune cells, in particular the TLR7 and TLR8 r

Updated on:May 30,2024