Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on: June 06,2024

Enzyme-activating antibodies revealed as marker for most severe form of rheumatoid arthritis

by Johns Hopkins University School of MedicineThe proposed binding site of the PAD4-activating antibody. The PAD4 enzyme is composed of two pieces (light gray and dark gray) that are connected in

Updated on:June 06,2024

Weekly leflunomide effective for early rheumatoid arthritis

(HealthDay)—A higher, weekly dose of leflunomide shows similar benefits to a daily dose for the treatment of mild-to-moderate early rheumatoid arthritis (ERA), according to a study published online Au

Updated on: April 08,2024

Weekly leflunomide effective for early rheumatoid arthritis

(HealthDay)—A higher, weekly dose of leflunomide shows similar benefits to a daily dose for the treatment of mild-to-moderate early rheumatoid arthritis (ERA), according to a study published online Au

Updated on:April 08,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on: June 17,2024

Study investigates rates of adverse events for common rheumatoid arthritis drug

by Brigham and Women's HospitalCredit: CC0 Public DomainMethotrexate is a common drug with a long history; for the past 40 years, it's been used to treat a range of diseases. Today it is

Updated on:June 17,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on: April 08,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on:April 08,2024

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on: May 05,2024

New study points to a better way to ward off asthma triggers

by La Jolla Institute for ImmunologyLeft: Lung tissue of untreated mice. Right: Lung tissue of mice treated with antibodies blocking OX40L and CD30L. Credit: Dr. Gurupreet Sethi, La Jolla Institu

Updated on:May 05,2024

With or without allergies, outcomes similar for hospitalized patients with COVID-19

byAmerican College of Allergy, Asthma, and ImmunologyDuring the COVID-19 pandemic, attention has been focused on how those with both allergies and asthma might be affected should they become ill

Updated on: March 05,2024

With or without allergies, outcomes similar for hospitalized patients with COVID-19

byAmerican College of Allergy, Asthma, and ImmunologyDuring the COVID-19 pandemic, attention has been focused on how those with both allergies and asthma might be affected should they become ill

Updated on:March 05,2024

Study finds gut microbiota influence severity of respiratory viral infection

by Georgia State UniversityThis picture illustrates an example of gut microbiota composition dictating how resident lung alveolar macrophages (AM) respond to viral infection. The presence of segm

Updated on: March 07,2024

Study finds gut microbiota influence severity of respiratory viral infection

by Georgia State UniversityThis picture illustrates an example of gut microbiota composition dictating how resident lung alveolar macrophages (AM) respond to viral infection. The presence of segm

Updated on:March 07,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

AI model can quantify radiographic joint damage in rheumatoid arthritis

An international competition resulted in the development of algorithms that provide feasible, quick, and accurate methods to quantify joint damage in rheumatoid arthritis (RA), according to a study pu

Updated on: June 26,2024

AI model can quantify radiographic joint damage in rheumatoid arthritis

An international competition resulted in the development of algorithms that provide feasible, quick, and accurate methods to quantify joint damage in rheumatoid arthritis (RA), according to a study pu

Updated on:June 26,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on: October 10,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on:October 10,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on: July 11,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on:July 11,2024

New study indicates why children are likelier to develop food allergies

by La Jolla Institute for Allergy and ImmunologyA study by LJI researchers identified a T cell population that renders normal food non-allergenic. Credit: La Jolla Institute for Allergy and Immun

Updated on: May 08,2024

New study indicates why children are likelier to develop food allergies

by La Jolla Institute for Allergy and ImmunologyA study by LJI researchers identified a T cell population that renders normal food non-allergenic. Credit: La Jolla Institute for Allergy and Immun

Updated on:May 08,2024