New insights on B cells: Researchers explore building better antibodies and curbing autoimmune diseases

by Nancy Fliesler,Harvard Medical SchoolGb3 drives affinity and diversity of antibody responses and protects against viral infection. Credit:Science(2024). DOI: 10.1126/science.adg05

Updated on: April 28,2024

New insights on B cells: Researchers explore building better antibodies and curbing autoimmune diseases

by Nancy Fliesler,Harvard Medical SchoolGb3 drives affinity and diversity of antibody responses and protects against viral infection. Credit:Science(2024). DOI: 10.1126/science.adg05

Updated on:April 28,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on: April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on:April 09,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on: June 26,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on:June 26,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on: April 08,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on:April 08,2024

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on: May 08,2024

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on:May 08,2024

New device for low-cost single-cell analysis identifies fibroblast subtypes in rheumatoid arthritis patients

by New York Genome CenterResearchers at the New York Genome Center (NYGC) and New York University (NYU) have taken steps to facilitate broad access to single-cell sequencing by developing a 3-D-printe

Updated on: April 07,2024

New device for low-cost single-cell analysis identifies fibroblast subtypes in rheumatoid arthritis patients

by New York Genome CenterResearchers at the New York Genome Center (NYGC) and New York University (NYU) have taken steps to facilitate broad access to single-cell sequencing by developing a 3-D-printe

Updated on:April 07,2024

Omega-3s could boost immunotherapy's cancer-fighting power

by Experimental BiologyOmega-3 supplementation improves the efficacy of immunotherapy in subcutaneous murine MB49 bladder cancer tumors. Credit: Abigail Kelly, Beth Israel Deaconess Medical Center/Har

Updated on: April 20,2024

Omega-3s could boost immunotherapy's cancer-fighting power

by Experimental BiologyOmega-3 supplementation improves the efficacy of immunotherapy in subcutaneous murine MB49 bladder cancer tumors. Credit: Abigail Kelly, Beth Israel Deaconess Medical Center/Har

Updated on:April 20,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on: July 11,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on:July 11,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on: March 27,2024

Lymph node-like biomaterial scaffold for augmenting CAR-T cell therapy

byScience China PressOn the top, the schematic illustration shows the structure of scaffold, the seeding and proliferation of CAR-T cells within the scaffold after intratumor injection. On the b

Updated on:March 27,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024

OM85: How bacteria in a capsule could protect us from coronavirus and other respiratory infections

by Peter Sly,The ConversationCredit: AI-generated imageScientists around the world are continuing to test countless vaccines and drugs in the hope of finding effective ways to prevent and treat

Updated on: April 20,2024

OM85: How bacteria in a capsule could protect us from coronavirus and other respiratory infections

by Peter Sly,The ConversationCredit: AI-generated imageScientists around the world are continuing to test countless vaccines and drugs in the hope of finding effective ways to prevent and treat

Updated on:April 20,2024

Air pollution linked to increased rheumatoid arthritis severity

(HealthDay)—Air pollution is associated with increased rheumatoid arthritis (RA) disease severity, according to a study published in the October issue ofRheumatology.Giovanni Adami, M.D., Ph.D.,

Updated on: June 01,2024

Air pollution linked to increased rheumatoid arthritis severity

(HealthDay)—Air pollution is associated with increased rheumatoid arthritis (RA) disease severity, according to a study published in the October issue ofRheumatology.Giovanni Adami, M.D., Ph.D.,

Updated on:June 01,2024