Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b

Updated on: July 09,2024 0

Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b

Updated on:July 09,2024 0

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on: May 29,2024 7

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Updated on:May 29,2024 7

OX40-positive follicular helper T cells control rheumatoid arthritis

by University of TsukubaCredit: CC0 Public DomainRheumatoid arthritis is a progressive autoimmune disease most frequently characterized by pain, swelling, and stiffness in joints. Increased numbe

Updated on: June 17,2024 7

OX40-positive follicular helper T cells control rheumatoid arthritis

by University of TsukubaCredit: CC0 Public DomainRheumatoid arthritis is a progressive autoimmune disease most frequently characterized by pain, swelling, and stiffness in joints. Increased numbe

Updated on:June 17,2024 7

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on: June 17,2024 6

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on:June 17,2024 6

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024 4

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024 4

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on: September 04,2024 0

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on:September 04,2024 0

Low dose steroid use not associated with substantial weight gain or hypertension in patients with rheumatoid arthritis

by American College of PhysiciansCredit: Unsplash/CC0 Public DomainAn analysis of randomized controlled trials has found that the use of low-dose glucocorticoids was not associated with substanti

Updated on: June 17,2024 3

Low dose steroid use not associated with substantial weight gain or hypertension in patients with rheumatoid arthritis

by American College of PhysiciansCredit: Unsplash/CC0 Public DomainAn analysis of randomized controlled trials has found that the use of low-dose glucocorticoids was not associated with substanti

Updated on:June 17,2024 3

One in five patients with rheumatoid arthritis went undiagnosed during the pandemic

by King's College LondonCredit: Unsplash/CC0 Public DomainThe number of new diagnoses of rheumatoid arthritis fell by 20% in the first year of the COVID-19 pandemic, new research suggests.The

Updated on: May 29,2024 5

One in five patients with rheumatoid arthritis went undiagnosed during the pandemic

by King's College LondonCredit: Unsplash/CC0 Public DomainThe number of new diagnoses of rheumatoid arthritis fell by 20% in the first year of the COVID-19 pandemic, new research suggests.The

Updated on:May 29,2024 5

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on: June 17,2024 5

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on:June 17,2024 5

Scientists discover how to improve vaccine response to potentially deadly bacterium

byTrinity College DublinScanning electromicrograph of Staphylococcus aureus bacteria. Credit: NIAIDResearchers from Trinity College Dublin have taken a leap forward in understanding how we might

Updated on: July 09,2024 0

Scientists discover how to improve vaccine response to potentially deadly bacterium

byTrinity College DublinScanning electromicrograph of Staphylococcus aureus bacteria. Credit: NIAIDResearchers from Trinity College Dublin have taken a leap forward in understanding how we might

Updated on:July 09,2024 0

New research predicts whether rheumatoid arthritis patients will respond to treatment

by Queen Mary, University of LondonCredit: CC0 Public DomainA new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsive

Updated on: June 17,2024 3

New research predicts whether rheumatoid arthritis patients will respond to treatment

by Queen Mary, University of LondonCredit: CC0 Public DomainA new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsive

Updated on:June 17,2024 3

New device monitors levels of inflammation-associated C-reactive protein in real time

byPolish Academy of SciencesGraphical abstract. Credit:ACS Sensors(2024). DOI: 10.1021/acssensors.4c00249As inflammation is the body's natural immune response to disease or infec

Updated on: September 02,2024 0

New device monitors levels of inflammation-associated C-reactive protein in real time

byPolish Academy of SciencesGraphical abstract. Credit:ACS Sensors(2024). DOI: 10.1021/acssensors.4c00249As inflammation is the body's natural immune response to disease or infec

Updated on:September 02,2024 0