Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on: March 27,2024

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on:March 27,2024

Scientists discover new mechanism controlling T-cells in inflammation

by Melissa Rohman,Northwestern UniversityGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.08.008Northwestern Medicine scientists have discovered a new mechanism

Updated on: October 10,2024

Scientists discover new mechanism controlling T-cells in inflammation

by Melissa Rohman,Northwestern UniversityGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.08.008Northwestern Medicine scientists have discovered a new mechanism

Updated on:October 10,2024

Arthritis sufferers excluded from everyday life

by Fran Strachan,University of New South WalesCredit: ThinkstockArthritis is the second leading cause of disability in Australia with many sufferers so severely disabled they cannot engage in ba

Updated on: March 24,2024

Arthritis sufferers excluded from everyday life

by Fran Strachan,University of New South WalesCredit: ThinkstockArthritis is the second leading cause of disability in Australia with many sufferers so severely disabled they cannot engage in ba

Updated on:March 24,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on: March 24,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on:March 24,2024

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on: May 05,2024

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on:May 05,2024

Rheumatoid arthritis tied to heavy economic and human burdens

by Lori SolomonRheumatoid arthritis (RA) is associated with higher health care expenditures and suboptimal quality of life in U.S. adults, according to a studypublishedonline Aug. 6 in&nbs

Updated on: October 09,2024

Rheumatoid arthritis tied to heavy economic and human burdens

by Lori SolomonRheumatoid arthritis (RA) is associated with higher health care expenditures and suboptimal quality of life in U.S. adults, according to a studypublishedonline Aug. 6 in&nbs

Updated on:October 09,2024

Early-life exposure to famine linked to increased odds of RA

(HealthDay)—Individuals exposed to famine in utero or in early childhood have an increased likelihood of developing rheumatoid arthritis (RA) in adulthood, according to a study published in the April

Updated on: March 28,2024

Early-life exposure to famine linked to increased odds of RA

(HealthDay)—Individuals exposed to famine in utero or in early childhood have an increased likelihood of developing rheumatoid arthritis (RA) in adulthood, according to a study published in the April

Updated on:March 28,2024

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on: June 06,2024

Numerous jobs linked to increased risk of knee reconstruction

by University of SydneyExercises to avoid and treat osteoarthritis. Credit: Institute of Bone and Joint Research, University of SydneyKnee replacements are a huge burden on society and individual

Updated on:June 06,2024

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to

Updated on: April 08,2024

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to

Updated on:April 08,2024

Oral contraceptives may impact aspects of arthritis in women

by WileyThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterNew research indicates that use of oral contraceptives may provide benefits for women with inflammato

Updated on: April 17,2024

Oral contraceptives may impact aspects of arthritis in women

by WileyThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterNew research indicates that use of oral contraceptives may provide benefits for women with inflammato

Updated on:April 17,2024

Women with rheumatoid arthritis more likely to achieve remission if they take sex hormones, finds research

by University of South AustraliaGraphical abstract. Credit:Rheumatology(2022). DOI: 10.1093/rheumatology/keac357A large study of women with rheumatoid arthritis has found that those t

Updated on: June 01,2024

Women with rheumatoid arthritis more likely to achieve remission if they take sex hormones, finds research

by University of South AustraliaGraphical abstract. Credit:Rheumatology(2022). DOI: 10.1093/rheumatology/keac357A large study of women with rheumatoid arthritis has found that those t

Updated on:June 01,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024