Study offers insight into management of patients who have interstitial pneumonia with autoimmune features

by UT Southwestern Medical CenterCredit: Unsplash/CC0 Public DomainInterstitial pneumonia with autoimmune features (IPAF) is a disease with many possible causes and no standard of care, making it

Updated on: June 01,2024

Study offers insight into management of patients who have interstitial pneumonia with autoimmune features

by UT Southwestern Medical CenterCredit: Unsplash/CC0 Public DomainInterstitial pneumonia with autoimmune features (IPAF) is a disease with many possible causes and no standard of care, making it

Updated on:June 01,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on: June 15,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on:June 15,2024

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on: March 07,2024

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on:March 07,2024

Tracking down the genetic causes of lupus to personalize treatment

by University of California - BerkeleyMany autoimmune diseases, including lupus, have been linked to problems with the toll-like receptors (TLR) on immune cells, in particular the TLR7 and TLR8 r

Updated on: May 30,2024

Tracking down the genetic causes of lupus to personalize treatment

by University of California - BerkeleyMany autoimmune diseases, including lupus, have been linked to problems with the toll-like receptors (TLR) on immune cells, in particular the TLR7 and TLR8 r

Updated on:May 30,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on: March 07,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on:March 07,2024

New device monitors levels of inflammation-associated C-reactive protein in real time

byPolish Academy of SciencesGraphical abstract. Credit:ACS Sensors(2024). DOI: 10.1021/acssensors.4c00249As inflammation is the body's natural immune response to disease or infec

Updated on: September 02,2024

New device monitors levels of inflammation-associated C-reactive protein in real time

byPolish Academy of SciencesGraphical abstract. Credit:ACS Sensors(2024). DOI: 10.1021/acssensors.4c00249As inflammation is the body's natural immune response to disease or infec

Updated on:September 02,2024

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on: March 30,2024

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on:March 30,2024

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on: April 22,2024

SARS-CoV-2 variant B.1.617 attacks immune system

by The German Primate CenterThe spike protein on the surface of SARS-CoV-2 virions mediates entry into target cells. It Is the main target for neutralizing antibodies that are produced following

Updated on:April 22,2024

An existing drug may change tumor-associated macrophages back to cancer fighters

by Jeff Hansen,University of Alabama at BirminghamCredit: Unsplash/CC0 Public DomainA form of cell communication called hedgehog signaling is vital for embryonic development in mammals. Bu

Updated on: March 26,2024

An existing drug may change tumor-associated macrophages back to cancer fighters

by Jeff Hansen,University of Alabama at BirminghamCredit: Unsplash/CC0 Public DomainA form of cell communication called hedgehog signaling is vital for embryonic development in mammals. Bu

Updated on:March 26,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024

New juvenile idiopathic arthritis guideline emphasizes disease-modifying treatments

by American College of RheumatologyCredit: CC0 Public DomainThe American College of Rheumatology (ACR) will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Co

Updated on: May 08,2024

New juvenile idiopathic arthritis guideline emphasizes disease-modifying treatments

by American College of RheumatologyCredit: CC0 Public DomainThe American College of Rheumatology (ACR) will preview the 2021 Guideline for the Treatment of Juvenile Idiopathic Arthritis at ACR Co

Updated on:May 08,2024

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on: March 07,2024

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on:March 07,2024