TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on: April 24,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on:April 24,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on: March 07,2024

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on:March 07,2024

Team publishes findings about compound with potential for treating rheumatoid arthritis

by Montana State UniversityThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterMontana State University researchers and their collaborators have published their

Updated on: April 20,2024

Team publishes findings about compound with potential for treating rheumatoid arthritis

by Montana State UniversityThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterMontana State University researchers and their collaborators have published their

Updated on:April 20,2024

Myogenes identified for spondyloarthritis synovitis

There are disease-specific and inflammation-independent stromal alterations in spondyloarthritis synovitis, according to a study published online Sept. 12 inArthritis & Rheumatism.(HealthDay

Updated on: April 08,2024

Myogenes identified for spondyloarthritis synovitis

There are disease-specific and inflammation-independent stromal alterations in spondyloarthritis synovitis, according to a study published online Sept. 12 inArthritis & Rheumatism.(HealthDay

Updated on:April 08,2024

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on: April 24,2024

An unconventional ion channel

by Ludwig Maximilian University of MunichTRPML2 channels (green) on vacuolin-enlarged fast recycling vesicles (positive for the fast-recycling marker RAB4A (red)), permitting to microdissect thes

Updated on:April 24,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on: May 05,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on:May 05,2024

Monash researchers bringing hope to lupus patients

by Monash UniversityResearchers at Monash University are leading the world's largest study to describe lupus patients and disease characteristics, bringing treat-to-target options for lupus a

Updated on: March 24,2024

Monash researchers bringing hope to lupus patients

by Monash UniversityResearchers at Monash University are leading the world's largest study to describe lupus patients and disease characteristics, bringing treat-to-target options for lupus a

Updated on:March 24,2024

'Junk DNA' is a double-edged sword, and the good side has anti-cancer potential

by University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainRochester biologists show how selfish genetic elements that can cause tumors may also trigger the death of cancer cells.S

Updated on: March 13,2024

'Junk DNA' is a double-edged sword, and the good side has anti-cancer potential

by University of Rochester Medical CenterCredit: Pixabay/CC0 Public DomainRochester biologists show how selfish genetic elements that can cause tumors may also trigger the death of cancer cells.S

Updated on:March 13,2024

The novel mechanisms for inflammation and cancer induced by HTLV-1

by Kumamoto UniversityCredit: Unsplash/CC0 Public DomainA research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes i

Updated on: April 16,2024

The novel mechanisms for inflammation and cancer induced by HTLV-1

by Kumamoto UniversityCredit: Unsplash/CC0 Public DomainA research group from Kumamoto University, Japan, has clarified the mechanism by which human T-cell leukemia virus type 1 (HTLV-1) causes i

Updated on:April 16,2024

Moms with systemic lupus erythematosus at double the risk of having premature or growth-restricted babies, finds study

by British Medical JournalCredit: Unsplash/CC0 Public DomainMothers with the long term autoimmune disorder, systemic lupus erythematosus, or SLE for short, run more than double the risk of giving

Updated on: June 05,2024

Moms with systemic lupus erythematosus at double the risk of having premature or growth-restricted babies, finds study

by British Medical JournalCredit: Unsplash/CC0 Public DomainMothers with the long term autoimmune disorder, systemic lupus erythematosus, or SLE for short, run more than double the risk of giving

Updated on:June 05,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on: April 08,2024

Gender, high DAS28-P index predictive of pain in early RA

(HealthDay) -- For patients with rheumatoid arthritis (RA), female gender and having a high proportion of disease activity score (DAS28) attributable to patient-reported components (joint tenderness a

Updated on:April 08,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on: March 25,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on:March 25,2024