An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024

Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio

Updated on: April 27,2024

Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio

Updated on:April 27,2024

Hope for patients with rare Sjögren's syndrome

by Newcastle UniversityProfessor Fai Ng. Credit: Newcastle UniversityA new study has shed light on a debilitating autoimmune condition by identifying a number of subtypes of the disease which cou

Updated on: March 24,2024

Hope for patients with rare Sjögren's syndrome

by Newcastle UniversityProfessor Fai Ng. Credit: Newcastle UniversityA new study has shed light on a debilitating autoimmune condition by identifying a number of subtypes of the disease which cou

Updated on:March 24,2024

An asthma vaccine effective in mice

by Pasteur InstituteCredit: CC0 Public DomainInserm teams led by Laurent Reber (Infinity, Toulouse) and Pierre Bruhns (Humoral Immunity, Institut Pasteur, Paris) and French company NEOVACS have d

Updated on: April 24,2024

An asthma vaccine effective in mice

by Pasteur InstituteCredit: CC0 Public DomainInserm teams led by Laurent Reber (Infinity, Toulouse) and Pierre Bruhns (Humoral Immunity, Institut Pasteur, Paris) and French company NEOVACS have d

Updated on:April 24,2024

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on: January 26,2024

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on:January 26,2024

Smoking cessation may reduce risk of rheumatoid arthritis

by Brigham and Women's HospitalCredit: CC0 Public DomainSmoking is an important risk factor for developing the most common form of rheumatoid arthritis (RA) and other inflammatory diseases, b

Updated on: May 13,2024

Smoking cessation may reduce risk of rheumatoid arthritis

by Brigham and Women's HospitalCredit: CC0 Public DomainSmoking is an important risk factor for developing the most common form of rheumatoid arthritis (RA) and other inflammatory diseases, b

Updated on:May 13,2024

Fetal heart rate monitoring can help manage high-risk pregnancies

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that heart rate m

Updated on: May 08,2024

Fetal heart rate monitoring can help manage high-risk pregnancies

by American College of RheumatologyCredit: CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that heart rate m

Updated on:May 08,2024

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on: March 19,2024

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on:March 19,2024

How RNA editing affects the immune system

by CU Anschutz Medical CampusCredit: CC0 Public DomainThree University of Colorado Cancer Center researchers are part of a team that recently published a paper offering new insight into how the i

Updated on: April 22,2024

How RNA editing affects the immune system

by CU Anschutz Medical CampusCredit: CC0 Public DomainThree University of Colorado Cancer Center researchers are part of a team that recently published a paper offering new insight into how the i

Updated on:April 22,2024

Flu vaccine cuts mortality in rheumatoid arthritis patients

(HealthDay)—Patients with rheumatoid arthritis (RA), particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality, according to a study published i

Updated on: April 17,2024

Flu vaccine cuts mortality in rheumatoid arthritis patients

(HealthDay)—Patients with rheumatoid arthritis (RA), particularly elderly patients, who receive the influenza vaccine have significantly lower morbidity and mortality, according to a study published i

Updated on:April 17,2024

Impact of dietary interventions inconsistent in rheumatoid arthritis

(HealthDay)—For patients with rheumatoid arthritis (RA), the impact of dietary interventions is inconsistent, although some research indicates benefit for omega-3 supplementation, according to a revie

Updated on: April 07,2024

Impact of dietary interventions inconsistent in rheumatoid arthritis

(HealthDay)—For patients with rheumatoid arthritis (RA), the impact of dietary interventions is inconsistent, although some research indicates benefit for omega-3 supplementation, according to a revie

Updated on:April 07,2024

Factors examined for time to first therapy for biologic DMARD in RA

(HealthDay)—For older patients with rheumatoid arthritis (RA), there is considerable variation in time to receipt of first biologic disease-modifying antirheumatic drug (DMARD) after prescription of t

Updated on: April 07,2024

Factors examined for time to first therapy for biologic DMARD in RA

(HealthDay)—For older patients with rheumatoid arthritis (RA), there is considerable variation in time to receipt of first biologic disease-modifying antirheumatic drug (DMARD) after prescription of t

Updated on:April 07,2024