Genetic key to lupus shows potential of personalised medicine

by Australian National UniversityDr Julia Ellyard(Medical Xpress)—Medical researchers have used DNA sequencing to identify a gene variant responsible for causing lupus in a young patient.The deve

Updated on: June 15,2024

Genetic key to lupus shows potential of personalised medicine

by Australian National UniversityDr Julia Ellyard(Medical Xpress)—Medical researchers have used DNA sequencing to identify a gene variant responsible for causing lupus in a young patient.The deve

Updated on:June 15,2024

COVID-19 mutations and their links to excessive immune responses

by King Abdullah University of Science and TechnologySchematic representation summarizing the main findings. The KR mutant SARS-CoV-2 infected patients display high magnitude of immune response.

Updated on: April 13,2024

COVID-19 mutations and their links to excessive immune responses

by King Abdullah University of Science and TechnologySchematic representation summarizing the main findings. The KR mutant SARS-CoV-2 infected patients display high magnitude of immune response.

Updated on:April 13,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on: April 24,2024

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on:April 24,2024

Smokers who consume too much sodium at greater risk of developing rheumatoid arthritis

by Oxford University PressCredit: Vera Kratochvil/public domainA new study published online in the journalRheumatologytoday indicates that the interaction between high sodium intake a

Updated on: May 13,2024

Smokers who consume too much sodium at greater risk of developing rheumatoid arthritis

by Oxford University PressCredit: Vera Kratochvil/public domainA new study published online in the journalRheumatologytoday indicates that the interaction between high sodium intake a

Updated on:May 13,2024

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on: June 06,2024

Running, even in excess, doesn't lead to more osteoarthritis and hip replacements

by Dan Krotz,Lawrence Berkeley National LaboratoryCredit: Berkeley Lab photographer Roy Kaltschmidt(Medical Xpress)—Need another reason to dust off those running shoes in the back of the closet?

Updated on:June 06,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on: May 05,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on:May 05,2024

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on: September 18,2024

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on:September 18,2024

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024

Vascular disease in COVID-19 is not caused by viral infection of blood vessels

by University of QueenslandSARS-CoV-2 virus added to epithelial cells and infected cells shown in pink. Credit: University of QueenslandThe SARS-CoV-2 virus does not infect blood vessels, despite

Updated on: April 10,2024

Vascular disease in COVID-19 is not caused by viral infection of blood vessels

by University of QueenslandSARS-CoV-2 virus added to epithelial cells and infected cells shown in pink. Credit: University of QueenslandThe SARS-CoV-2 virus does not infect blood vessels, despite

Updated on:April 10,2024

Urine of COVID-19 patients could predict who will develop severe disease

by American Physiological SocietyCredit: Unsplash/CC0 Public DomainUrine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who w

Updated on: April 10,2024

Urine of COVID-19 patients could predict who will develop severe disease

by American Physiological SocietyCredit: Unsplash/CC0 Public DomainUrine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who w

Updated on:April 10,2024

Allergy diary' phone app classifies phenotypes in rhinitis

(HealthDay)—TheAllergy Diaryphone app can identify phenotypic differences between rhinitis groups, according to a study published online Jan. 10 inAllergy.Jean Bousquet, M.D., from t

Updated on: March 13,2024

Allergy diary' phone app classifies phenotypes in rhinitis

(HealthDay)—TheAllergy Diaryphone app can identify phenotypic differences between rhinitis groups, according to a study published online Jan. 10 inAllergy.Jean Bousquet, M.D., from t

Updated on:March 13,2024