CARv3-TEAM-E T-cell treatment beneficial for recurrent glioblastoma

by Elana GotkineFor patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-spec

Updated on: March 27,2024 0

CARv3-TEAM-E T-cell treatment beneficial for recurrent glioblastoma

by Elana GotkineFor patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-spec

Updated on:March 27,2024 0

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on: May 08,2024 8

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on:May 08,2024 8

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024 8

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024 8

Digitally reported patient outcomes tied to better disease control in rheumatoid arthritis

by Lori SolomonThe use of a digital health application with patient-reported outcomes is associated with an increase in disease control rate for adults with rheumatoid arthritis (RA), according to a s

Updated on: May 29,2024 4

Digitally reported patient outcomes tied to better disease control in rheumatoid arthritis

by Lori SolomonThe use of a digital health application with patient-reported outcomes is associated with an increase in disease control rate for adults with rheumatoid arthritis (RA), according to a s

Updated on:May 29,2024 4

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on: April 08,2024 11

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on:April 08,2024 11

A possible mechanism of lymphocyte deficiency in patients with COVID-19

by Russian Foundation for Basic ResearchCreative rendition of SARS-CoV-2 particles (not to scale). Credit: National Institute of Allergy and Infectious Diseases, NIHScientists from RUDN, National Medi

Updated on: April 10,2024 10

A possible mechanism of lymphocyte deficiency in patients with COVID-19

by Russian Foundation for Basic ResearchCreative rendition of SARS-CoV-2 particles (not to scale). Credit: National Institute of Allergy and Infectious Diseases, NIHScientists from RUDN, National Medi

Updated on:April 10,2024 10

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on: April 20,2024 14

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on:April 20,2024 14

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on: March 07,2024 15

Eyes serve as immunological barrier in fight against brain pathogens, finds study

by Yale University10x VISIUM Spatial sequencing of the mouse globe and optic nerve. Mouse eyes were processed using traditional FFPE-based histology preparation. Samples were processed using the

Updated on:March 07,2024 15

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on: April 24,2024 19

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on:April 24,2024 19

How chronic knee osteoarthritis pain affects cognitive function

by University of NottinghamCredit: CC0 Public DomainNew research suggests that chronic knee pain caused by osteoarthritis does not cause cognitive impairment in isolation, indicating that other f

Updated on: May 23,2024 6

How chronic knee osteoarthritis pain affects cognitive function

by University of NottinghamCredit: CC0 Public DomainNew research suggests that chronic knee pain caused by osteoarthritis does not cause cognitive impairment in isolation, indicating that other f

Updated on:May 23,2024 6

COVID-19 : Measuring viral RNA to predict which patients will die

by University of MontrealColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAI

Updated on: April 10,2024 11

COVID-19 : Measuring viral RNA to predict which patients will die

by University of MontrealColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAI

Updated on:April 10,2024 11

Developing new classification criteria for improving antiphospholipid syndrome research

by Hospital for Special SurgeryCredit: CC0 Public DomainAn international team of more than 80 collaborators led by Hospital for Special Surgery (HSS) investigators is developing new classificatio

Updated on: March 26,2024 13

Developing new classification criteria for improving antiphospholipid syndrome research

by Hospital for Special SurgeryCredit: CC0 Public DomainAn international team of more than 80 collaborators led by Hospital for Special Surgery (HSS) investigators is developing new classificatio

Updated on:March 26,2024 13