An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024 8

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024 8

Vascular disease in COVID-19 is not caused by viral infection of blood vessels

by University of QueenslandSARS-CoV-2 virus added to epithelial cells and infected cells shown in pink. Credit: University of QueenslandThe SARS-CoV-2 virus does not infect blood vessels, despite

Updated on: April 10,2024 15

Vascular disease in COVID-19 is not caused by viral infection of blood vessels

by University of QueenslandSARS-CoV-2 virus added to epithelial cells and infected cells shown in pink. Credit: University of QueenslandThe SARS-CoV-2 virus does not infect blood vessels, despite

Updated on:April 10,2024 15

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on: May 08,2024 8

Evolutionary study links subtle modifications in the morphology of the bipedal knee to osteoarthritis later in life

by Harvard UniversityA visual riff on the classic illustration, "March of Progress," highlighting the evolution of knee osteoarthritis. Credit: Tasha McAbee, Department of Orthopedics a

Updated on:May 08,2024 8

COVID-19 : Measuring viral RNA to predict which patients will die

by University of MontrealColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAI

Updated on: April 10,2024 11

COVID-19 : Measuring viral RNA to predict which patients will die

by University of MontrealColorized scanning electron micrograph of a cell (blue) heavily infected with SARS-CoV-2 virus particles (red), isolated from a patient sample. Image captured at the NIAI

Updated on:April 10,2024 11

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi

Updated on: April 09,2024 18

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi

Updated on:April 09,2024 18

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024 5

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024 5

Immune receptor thought to be linked to hearing loss in child cancer survivors confirmed in new study

by Yolanda Poffenroth, Michael Brown,University of AlbertaCredit: Pixabay/CC0 Public DomainPermanent hearing loss triggered by a common chemotherapy drug in half of children being treated for ca

Updated on: May 07,2024 16

Immune receptor thought to be linked to hearing loss in child cancer survivors confirmed in new study

by Yolanda Poffenroth, Michael Brown,University of AlbertaCredit: Pixabay/CC0 Public DomainPermanent hearing loss triggered by a common chemotherapy drug in half of children being treated for ca

Updated on:May 07,2024 16

Digitally reported patient outcomes tied to better disease control in rheumatoid arthritis

by Lori SolomonThe use of a digital health application with patient-reported outcomes is associated with an increase in disease control rate for adults with rheumatoid arthritis (RA), according to a s

Updated on: May 29,2024 4

Digitally reported patient outcomes tied to better disease control in rheumatoid arthritis

by Lori SolomonThe use of a digital health application with patient-reported outcomes is associated with an increase in disease control rate for adults with rheumatoid arthritis (RA), according to a s

Updated on:May 29,2024 4

An experimental vaccine against rheumatoid arthritis

by University of ToledoCredit: CC0 Public DomainResearchers at The University of Toledo have developed an experimental vaccine that shows significant promise in preventing rheumatoid arthritis, a

Updated on: June 28,2024 8

An experimental vaccine against rheumatoid arthritis

by University of ToledoCredit: CC0 Public DomainResearchers at The University of Toledo have developed an experimental vaccine that shows significant promise in preventing rheumatoid arthritis, a

Updated on:June 28,2024 8

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on: April 24,2024 19

A turncoat protein allows viruses to ride roughshod in the liver, paving the way to cancer

by Delthia Ricks , Medical XpressImages showing the distribution of tagged STING and HA-HPN proteins in liver cells. Credit: F. Hsin et al.,Science Signaling(2021)Chronic viral infections

Updated on:April 24,2024 19

Interdisciplinary guidelines to optimize the treatment of childhood arthritis

by Aarhus UniversityCredit: Unsplash/CC0 Public DomainPreviously, there were no uniform guidelines for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile ar

Updated on: April 07,2024 19

Interdisciplinary guidelines to optimize the treatment of childhood arthritis

by Aarhus UniversityCredit: Unsplash/CC0 Public DomainPreviously, there were no uniform guidelines for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile ar

Updated on:April 07,2024 19

How chronic knee osteoarthritis pain affects cognitive function

by University of NottinghamCredit: CC0 Public DomainNew research suggests that chronic knee pain caused by osteoarthritis does not cause cognitive impairment in isolation, indicating that other f

Updated on: May 23,2024 6

How chronic knee osteoarthritis pain affects cognitive function

by University of NottinghamCredit: CC0 Public DomainNew research suggests that chronic knee pain caused by osteoarthritis does not cause cognitive impairment in isolation, indicating that other f

Updated on:May 23,2024 6