New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on: March 07,2024

New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on:March 07,2024

Urine of COVID-19 patients could predict who will develop severe disease

by American Physiological SocietyCredit: Unsplash/CC0 Public DomainUrine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who w

Updated on: April 10,2024

Urine of COVID-19 patients could predict who will develop severe disease

by American Physiological SocietyCredit: Unsplash/CC0 Public DomainUrine analysis of COVID-19 patients revealed elevated levels of specific biomarkers of the immune system compared to those who w

Updated on:April 10,2024

New strategy for COVID-19 prophylaxis

by University of BonnPhD student Samira Marx and Prof. Dr. Gunther Hartmann - of the Cluster of Excellence ImmunoSensation2 at the University of Bonn in the lab. Credit: David FußhöllerSARS-CoV-2

Updated on: April 13,2024

New strategy for COVID-19 prophylaxis

by University of BonnPhD student Samira Marx and Prof. Dr. Gunther Hartmann - of the Cluster of Excellence ImmunoSensation2 at the University of Bonn in the lab. Credit: David FußhöllerSARS-CoV-2

Updated on:April 13,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on: March 25,2024

A novel animal model for analysing human natural killer cell functions in vivo

by Kawasaki CityFigure 1: Humanized mice were generated by transplanting 2.5 x 104 human cord blood-derived CD34+ HSC cells into irradiated NOG-IL-2 mice. After human CD34+ cell transplantation, human

Updated on:March 25,2024

Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on: March 19,2024

Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on:March 19,2024

New analysis finds belimumab improves cutaneous lupus erythematosus in patients with or without SLE

by American College of RheumatologyForest plot of clinical response in CLE with or without SLE in belimumab users vs. non-users at week 52. Credit: Significant Improvement in Cutaneous Lupus Eryt

Updated on: May 29,2024

New analysis finds belimumab improves cutaneous lupus erythematosus in patients with or without SLE

by American College of RheumatologyForest plot of clinical response in CLE with or without SLE in belimumab users vs. non-users at week 52. Credit: Significant Improvement in Cutaneous Lupus Eryt

Updated on:May 29,2024

Consensus statement issued on management of foot, ankle gout

(HealthDay)—The American College of Foot and Ankle Surgeons and the American Association of Nurse Practitioners-Orthopedics Specialty Practice Group have issued a new joint clinical consensus statemen

Updated on: April 20,2024

Consensus statement issued on management of foot, ankle gout

(HealthDay)—The American College of Foot and Ankle Surgeons and the American Association of Nurse Practitioners-Orthopedics Specialty Practice Group have issued a new joint clinical consensus statemen

Updated on:April 20,2024

Gut microbiome: Meet Roseburia intestinalis—the energy-producing bacterium that helps us fight against disease

by Conor Meehan,The ConversationCredit: Pixabay/CC0 Public DomainThe hundreds of species of microorganisms that comprise the microbiome all have different, unique roles.One of the important func

Updated on: March 27,2024

Gut microbiome: Meet Roseburia intestinalis—the energy-producing bacterium that helps us fight against disease

by Conor Meehan,The ConversationCredit: Pixabay/CC0 Public DomainThe hundreds of species of microorganisms that comprise the microbiome all have different, unique roles.One of the important func

Updated on:March 27,2024

COVID vaccines also help protect HIV patients

by Ruhr-Universitaet-BochumAnti-RBD titers in vaccinated PLWH and HIV-negative controls. (A) Scheme showing the two groups of the study - control (n = 20) and people living with HIV (PLWH; n = 71

Updated on: April 09,2024

COVID vaccines also help protect HIV patients

by Ruhr-Universitaet-BochumAnti-RBD titers in vaccinated PLWH and HIV-negative controls. (A) Scheme showing the two groups of the study - control (n = 20) and people living with HIV (PLWH; n = 71

Updated on:April 09,2024

Lockdown impact: Worsening symptoms for people with bone, joint and muscle pain

by University of East AngliaCredit: CC0 Public DomainPeople with bone, joint and muscle pain saw their symptoms worsen during lockdown—according to new research from the University of East Anglia

Updated on: May 26,2024

Lockdown impact: Worsening symptoms for people with bone, joint and muscle pain

by University of East AngliaCredit: CC0 Public DomainPeople with bone, joint and muscle pain saw their symptoms worsen during lockdown—according to new research from the University of East Anglia

Updated on:May 26,2024

Screening of patients with rheumatism improves insight into cardiovascular disease

by University of TwenteSince the fifties, researchers have observed that patients with rheumatoid arthritis have an increased mortality from cardiovascular disease. Patients with this form of rhe

Updated on: May 13,2024

Screening of patients with rheumatism improves insight into cardiovascular disease

by University of TwenteSince the fifties, researchers have observed that patients with rheumatoid arthritis have an increased mortality from cardiovascular disease. Patients with this form of rhe

Updated on:May 13,2024

Psoriasis patients can get clearer skin with at-home treatment instead of at doctors' offices, study suggests

by Alex Gardner,Perelman School of Medicine at the University of PennsylvaniaCredit: Estzer Miller on PixabayFor decades, people with psoriasis have been treated in clinics with narrowband ultra

Updated on: October 28,2024

Psoriasis patients can get clearer skin with at-home treatment instead of at doctors' offices, study suggests

by Alex Gardner,Perelman School of Medicine at the University of PennsylvaniaCredit: Estzer Miller on PixabayFor decades, people with psoriasis have been treated in clinics with narrowband ultra

Updated on:October 28,2024