STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on: April 22,2024

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on:April 22,2024

Study unveils the role of gamma-delta T cells in cancer immunology

byH. Lee Moffitt Cancer Center & Research InstituteComprehensive pan-cancer analysis of γδ TCRs. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101764A new study pu

Updated on: October 26,2024

Study unveils the role of gamma-delta T cells in cancer immunology

byH. Lee Moffitt Cancer Center & Research InstituteComprehensive pan-cancer analysis of γδ TCRs. Credit:Cell Reports Medicine(2024). DOI: 10.1016/j.xcrm.2024.101764A new study pu

Updated on:October 26,2024

Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on: March 24,2024

Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on:March 24,2024

A near-fatal Valley Fever case opens doors to new treatment method

by Ryan Hatoum,University of California, Los AngelesAbraham Gonzalez-Martinez, who had a dangerous case of Valley Fever, at UCLA Mattel Children’s Hospital. Credit: University of California, Los

Updated on: May 08,2024

A near-fatal Valley Fever case opens doors to new treatment method

by Ryan Hatoum,University of California, Los AngelesAbraham Gonzalez-Martinez, who had a dangerous case of Valley Fever, at UCLA Mattel Children’s Hospital. Credit: University of California, Los

Updated on:May 08,2024

COVID-19 causes some patients' immune systems to attack their own bodies, which may contribute to severe illness

by Matthew Woodruff,The ConversationCredit: Pixabay/CC0 Public DomainAround the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain

Updated on: April 10,2024

COVID-19 causes some patients' immune systems to attack their own bodies, which may contribute to severe illness

by Matthew Woodruff,The ConversationCredit: Pixabay/CC0 Public DomainAround the world, immunologists who retooled their labs to join the fight against SARS-CoV-2 are furiously trying to explain

Updated on:April 10,2024

Researchers validate pediatric 'allergic march' in largest national study of its kind

byChildren's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainIn the largest study of its kind, researchers from Children's Hospital of Philadelphia (CHOP) used electronic healt

Updated on: March 05,2024

Researchers validate pediatric 'allergic march' in largest national study of its kind

byChildren's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainIn the largest study of its kind, researchers from Children's Hospital of Philadelphia (CHOP) used electronic healt

Updated on:March 05,2024

New understanding of the gut immune system may hold promise for Crohn's disease patients

by Technical University of DenmarkCredit: Pixabay/CC0 Public DomainTricks played by certain disease-driving gut bacteria might help explain differences in how patients experience Crohn's dise

Updated on: March 19,2024

New understanding of the gut immune system may hold promise for Crohn's disease patients

by Technical University of DenmarkCredit: Pixabay/CC0 Public DomainTricks played by certain disease-driving gut bacteria might help explain differences in how patients experience Crohn's dise

Updated on:March 19,2024

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an

Updated on: June 15,2024

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an

Updated on:June 15,2024

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr

Updated on: June 06,2024

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr

Updated on:June 06,2024

New strategy for COVID-19 prophylaxis

by University of BonnPhD student Samira Marx and Prof. Dr. Gunther Hartmann - of the Cluster of Excellence ImmunoSensation2 at the University of Bonn in the lab. Credit: David FußhöllerSARS-CoV-2

Updated on: April 13,2024

New strategy for COVID-19 prophylaxis

by University of BonnPhD student Samira Marx and Prof. Dr. Gunther Hartmann - of the Cluster of Excellence ImmunoSensation2 at the University of Bonn in the lab. Credit: David FußhöllerSARS-CoV-2

Updated on:April 13,2024

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on: April 22,2024

RNA proofreading mistakes drive group of autoimmune diseases

by The Scripps Research InstituteScripps Research Professor Patrick Griffin, PhD, of Jupiter, Florida, co-chairman of the Department of Molecular Medicine, used hydrogen-deuterium exchange mass s

Updated on:April 22,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on: April 09,2024

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Updated on:April 09,2024