Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on: March 24,2024 19

Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on:March 24,2024 19

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on: May 14,2024 3

Targeting ion channels to manage osteoarthritis pain

by Melissa Rohman,Northwestern UniversityThe image depicts two drug receptor sites with the molecular structure of the Nav1.7 channel, and tamoxifen’s attenuation of nociceptor action potentials

Updated on:May 14,2024 3

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on: May 19,2024 3

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on:May 19,2024 3

Certain criteria may be better than others in RA assessment

(HealthDay)—For patients with rheumatoid arthritis (RA), the performances of the Clinical Disease Activity Index (CDAI) and Simplified Disease Activity Index (SDAI) appear to be better than that of th

Updated on: March 30,2024 13

Certain criteria may be better than others in RA assessment

(HealthDay)—For patients with rheumatoid arthritis (RA), the performances of the Clinical Disease Activity Index (CDAI) and Simplified Disease Activity Index (SDAI) appear to be better than that of th

Updated on:March 30,2024 13

New rheumatoid arthritis treatment shown to be effective: Half of all patients symptom-free within six months

by University of TwenteRheumatoid arthritis is a chronic disease characterized by inflammation of the joints. A rapid suppression of inflammation is important for a good prognosis. Marloes Vermee

Updated on: March 24,2024 14

New rheumatoid arthritis treatment shown to be effective: Half of all patients symptom-free within six months

by University of TwenteRheumatoid arthritis is a chronic disease characterized by inflammation of the joints. A rapid suppression of inflammation is important for a good prognosis. Marloes Vermee

Updated on:March 24,2024 14

A novel painless and reliable allergy test

byUniversity of BernCredit: CC0 Public DomainAlthough allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not al

Updated on: March 05,2024 12

A novel painless and reliable allergy test

byUniversity of BernCredit: CC0 Public DomainAlthough allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not al

Updated on:March 05,2024 12

Genes and cellular processes that contribute to the pathogenesis of RVVC found

by Bob Yirka , Medical XpressCandida albicans. Credit: Wikipedia.An international team of researchers has identified some of the genes and cellular processes that contribute to the pathogenesis of rec

Updated on: April 22,2024 12

Genes and cellular processes that contribute to the pathogenesis of RVVC found

by Bob Yirka , Medical XpressCandida albicans. Credit: Wikipedia.An international team of researchers has identified some of the genes and cellular processes that contribute to the pathogenesis of rec

Updated on:April 22,2024 12

Scientists use blood test to track gene expression in the brain

by Kayt Sukel,Rice UniversityScan of mouse hippocampus and cortex, where the red signal derives from immunostaining for the synthetic marker developed by the Szablowski lab and the blue from the

Updated on: April 23,2024 0

Scientists use blood test to track gene expression in the brain

by Kayt Sukel,Rice UniversityScan of mouse hippocampus and cortex, where the red signal derives from immunostaining for the synthetic marker developed by the Szablowski lab and the blue from the

Updated on:April 23,2024 0

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on: April 09,2024 17

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on:April 09,2024 17

FDA approves new treatment for dust mite allergies

(HealthDay)—A new treatment for dust mite allergies has won approval from the U.S. Food and Drug Administration.Odactra is a year-round, once-a-day tablet that's dissolved under the tongue. It&#39

Updated on: April 15,2024 11

FDA approves new treatment for dust mite allergies

(HealthDay)—A new treatment for dust mite allergies has won approval from the U.S. Food and Drug Administration.Odactra is a year-round, once-a-day tablet that's dissolved under the tongue. It&#39

Updated on:April 15,2024 11

Diet unlikely to ease progression of osteoarthritis, rheumatoid arthritis

by British Medical JournalCredit: CC0 Public DomainDiet is unlikely to make any difference to the progression of osteoarthritis and rheumatoid arthritis, finds a review of the existing scientific

Updated on: April 07,2024 19

Diet unlikely to ease progression of osteoarthritis, rheumatoid arthritis

by British Medical JournalCredit: CC0 Public DomainDiet is unlikely to make any difference to the progression of osteoarthritis and rheumatoid arthritis, finds a review of the existing scientific

Updated on:April 07,2024 19

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024 18

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024 18