St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on: April 22,2024

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on:April 22,2024

Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses

byUniversity of CambridgeBiochemist Professor Anne Willis and immunologist Dr James Thaventhiran at the MRC Toxicology Unit at the University of Cambridge led this work. Credit: Mike Thornton, S

Updated on: January 26,2024

Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses

byUniversity of CambridgeBiochemist Professor Anne Willis and immunologist Dr James Thaventhiran at the MRC Toxicology Unit at the University of Cambridge led this work. Credit: Mike Thornton, S

Updated on:January 26,2024

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on: January 26,2024

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on:January 26,2024

We are getting older and heavier, and osteoarthritis is increasing

by Lund UniversityCredit: CC0 Public DomainThe number of patients with osteoarthritis has increased dramatically since the 1950s. Along with diabetes, the illness is now one of the fastest-growin

Updated on: June 01,2024

We are getting older and heavier, and osteoarthritis is increasing

by Lund UniversityCredit: CC0 Public DomainThe number of patients with osteoarthritis has increased dramatically since the 1950s. Along with diabetes, the illness is now one of the fastest-growin

Updated on:June 01,2024

Skin must develop tolerance to 'good' bacteria early in life, says new study

by Pete Farley,University of California, San FranciscoHuman skin structure. Credit: WikipediaA wave of specialized immune cells entering the skin in early life may induce tolerance to the hundre

Updated on: April 24,2024

Skin must develop tolerance to 'good' bacteria early in life, says new study

by Pete Farley,University of California, San FranciscoHuman skin structure. Credit: WikipediaA wave of specialized immune cells entering the skin in early life may induce tolerance to the hundre

Updated on:April 24,2024

'Mix and match' assembly instructions guide immune cell attacks

by Walter and Eliza Hall Institute of Medical ResearchAssociate Professor Matthew Call (left) and Dr Melissa Call discovered a unique way that immune cells respond to, and kill, diseased and canc

Updated on: March 13,2024

'Mix and match' assembly instructions guide immune cell attacks

by Walter and Eliza Hall Institute of Medical ResearchAssociate Professor Matthew Call (left) and Dr Melissa Call discovered a unique way that immune cells respond to, and kill, diseased and canc

Updated on:March 13,2024

RNA sequencing used to discover novel genes and pathways in celiac disease

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers at the Mucosal Immunology and Biology Research Center at MassGeneral Hospital for Children (MGHfC) have discovered novel gene

Updated on: April 22,2024

RNA sequencing used to discover novel genes and pathways in celiac disease

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers at the Mucosal Immunology and Biology Research Center at MassGeneral Hospital for Children (MGHfC) have discovered novel gene

Updated on:April 22,2024

Antihistamines can be helpful during spring allergy season and as COVID vaccines roll out, for which rashes are common

byMcMaster UniversityCredit: Pixabay/CC0 Public DomainIf you are one of the millions of people worldwide suffering from allergies, you may take an antihistamine pill to ward off hives, sneezing

Updated on: March 02,2024

Antihistamines can be helpful during spring allergy season and as COVID vaccines roll out, for which rashes are common

byMcMaster UniversityCredit: Pixabay/CC0 Public DomainIf you are one of the millions of people worldwide suffering from allergies, you may take an antihistamine pill to ward off hives, sneezing

Updated on:March 02,2024

New study points to another possible correlation between sleep and overall good health

by Nova Southeastern UniversityJaime Tartar, Ph.D., Nova Southeastern University. Credit: Nova Southeastern UniversityAs if you didn't already have enough to worry about to keep you up at nig

Updated on: May 08,2024

New study points to another possible correlation between sleep and overall good health

by Nova Southeastern UniversityJaime Tartar, Ph.D., Nova Southeastern University. Credit: Nova Southeastern UniversityAs if you didn't already have enough to worry about to keep you up at nig

Updated on:May 08,2024

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an

Updated on: June 15,2024

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an

Updated on:June 15,2024

Screening and treating infections in AIIRD

by European Alliance of Associations for Rheumatology (EULAR)Typical screening for hepatitis B virus (HBV) status include HBsAg, anti-HBcore and anti-HBs. HBsAg-positive patients (HBV carriers) would

Updated on: May 26,2024

Screening and treating infections in AIIRD

by European Alliance of Associations for Rheumatology (EULAR)Typical screening for hepatitis B virus (HBV) status include HBsAg, anti-HBcore and anti-HBs. HBsAg-positive patients (HBV carriers) would

Updated on:May 26,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on: April 28,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on:April 28,2024