How an immune response is driven by one letter difference in DNA

byRadboud UniversityA biphasic circuit regulates IL-1β and IL-37 expression to coordinate pro- and anti-inflammatory processes from within a single TAD. The two functionally opposed states of th

Updated on: January 26,2024

How an immune response is driven by one letter difference in DNA

byRadboud UniversityA biphasic circuit regulates IL-1β and IL-37 expression to coordinate pro- and anti-inflammatory processes from within a single TAD. The two functionally opposed states of th

Updated on:January 26,2024

Disease control, safe medications critical to pregnancies for women with rheumatic disease

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainPregnant women with active rheumatic disease carry a higher risk of adverse outcomes than the general population including hypert

Updated on: June 17,2024

Disease control, safe medications critical to pregnancies for women with rheumatic disease

by UT Southwestern Medical CenterCredit: Pixabay/CC0 Public DomainPregnant women with active rheumatic disease carry a higher risk of adverse outcomes than the general population including hypert

Updated on:June 17,2024

The promise of precision medicine for rheumatoid arthritis

by Yale UniversityA hand affected by rheumatoid arthritis. Credit: James Heilman, MD/WikipediaIn a new study, a Yale-led research team identified the mechanism of a gene that raises the risk of s

Updated on: May 13,2024

The promise of precision medicine for rheumatoid arthritis

by Yale UniversityA hand affected by rheumatoid arthritis. Credit: James Heilman, MD/WikipediaIn a new study, a Yale-led research team identified the mechanism of a gene that raises the risk of s

Updated on:May 13,2024

Mortality rate up for Koreans with rheumatoid arthritis

(HealthDay)—Korean patients with rheumatoid arthritis (RA) have increased mortality rates compared with the general population, according to a study published online Jan. 19 in theInternational

Updated on: May 08,2024

Mortality rate up for Koreans with rheumatoid arthritis

(HealthDay)—Korean patients with rheumatoid arthritis (RA) have increased mortality rates compared with the general population, according to a study published online Jan. 19 in theInternational

Updated on:May 08,2024

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an

Updated on: June 15,2024

Findings give hope to plant extract as possible lupus treatment

by University of HoustonNew findings by UH biomedical engineer Chandra Mohan and his team raise hope for a new class of drugs to treat lupus that may not include the long list of adverse risks an

Updated on:June 15,2024

Phosphorylation of Regnase-1 lets IL-17 run amok

by Osaka UniversityCredit: CC0 Public DomainWhen considering the role of the key immune molecule interleukin (IL)-17, the phrase "too much of a good thing" springs to mind. Because unli

Updated on: April 22,2024

Phosphorylation of Regnase-1 lets IL-17 run amok

by Osaka UniversityCredit: CC0 Public DomainWhen considering the role of the key immune molecule interleukin (IL)-17, the phrase "too much of a good thing" springs to mind. Because unli

Updated on:April 22,2024

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on: January 26,2024

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on:January 26,2024

Hope for treating autoimmune diseases: Researchers explore diagnostic role of the systemic inflammation index

by Flinders UniversityCredit: Unsplash/CC0 Public DomainA routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of

Updated on: April 06,2024

Hope for treating autoimmune diseases: Researchers explore diagnostic role of the systemic inflammation index

by Flinders UniversityCredit: Unsplash/CC0 Public DomainA routine blood test that measures a patient's inflammation levels could improve the early diagnosis and management of a wide range of

Updated on:April 06,2024

Study discovers how chronic lung conditions affect children's immune system

by Murdoch Children's Research InstituteImmune cell and soluble analyte profiling of BAL from children with CSLD, wheeze and controls. Credit:Mucosal Immunology(2024). DOI: 10.101

Updated on: April 06,2024

Study discovers how chronic lung conditions affect children's immune system

by Murdoch Children's Research InstituteImmune cell and soluble analyte profiling of BAL from children with CSLD, wheeze and controls. Credit:Mucosal Immunology(2024). DOI: 10.101

Updated on:April 06,2024

Scientists pioneer immunotherapy technique for autoimmune diseases

byMayo ClinicMSCs are transduced to express CAR and maintain stem-like features following transduction and stimulation. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s4155

Updated on: April 06,2024

Scientists pioneer immunotherapy technique for autoimmune diseases

byMayo ClinicMSCs are transduced to express CAR and maintain stem-like features following transduction and stimulation. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s4155

Updated on:April 06,2024

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on: April 22,2024

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on:April 22,2024

Rehab or steroid shots: What's best for arthritic knees?

by Dennis Thompson(HealthDay)—Physical therapy for knee arthritis tends to cost patients more out-of-pocket and involves a lot more hassle than a quick steroid shot to soothe an aching joint.But in th

Updated on: May 23,2024

Rehab or steroid shots: What's best for arthritic knees?

by Dennis Thompson(HealthDay)—Physical therapy for knee arthritis tends to cost patients more out-of-pocket and involves a lot more hassle than a quick steroid shot to soothe an aching joint.But in th

Updated on:May 23,2024