Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024 18

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024 18

Adverse childhood experiences negatively impact adults with lupus

by University of California, San FranciscoCredit: CC0 Public DomainAdults with lupus who report having had adverse childhood experiences (ACEs), such as abuse, neglect and household challenges, r

Updated on: May 13,2024 6

Adverse childhood experiences negatively impact adults with lupus

by University of California, San FranciscoCredit: CC0 Public DomainAdults with lupus who report having had adverse childhood experiences (ACEs), such as abuse, neglect and household challenges, r

Updated on:May 13,2024 6

Study examines care received by patients with knee osteoarthritis

by WileyCredit: CC0 Public DomainNew research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and

Updated on: May 19,2024 5

Study examines care received by patients with knee osteoarthritis

by WileyCredit: CC0 Public DomainNew research reveals that only a minority of U.S. Medicare beneficiaries with knee osteoarthritis in 2005-2010 used non-surgical care such as physical therapy and

Updated on:May 19,2024 5

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on: April 22,2024 0

Evolutionary origin of mysterious immune system molecule in humans revealed

by Ashley WennersHerron,Pennsylvania State UniversityThe Joining chain shares three characteristics with the CXCL chemokine genes, including the same number of exons, which encode the protein, a

Updated on:April 22,2024 0

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on: April 24,2024 13

An extra X chromosome-linked gene may explain decreased viral infection severity in females

by University of California, Los AngelesCredit: CC0 Public DomainIt has long been known that viral infections can be more severe in males than females, but the question as to why has remained a m

Updated on:April 24,2024 13

Trials bring hope for world–first rheumatoid arthritis treatment

by University of QueenslandUQ’s Diamantina Institute Professor Ranjeny Thomas. Credit: University of QueenslandHuman trials of an innovative treatment for rheumatoid arthritis developed by The Un

Updated on: March 24,2024 10

Trials bring hope for world–first rheumatoid arthritis treatment

by University of QueenslandUQ’s Diamantina Institute Professor Ranjeny Thomas. Credit: University of QueenslandHuman trials of an innovative treatment for rheumatoid arthritis developed by The Un

Updated on:March 24,2024 10

Trial compares therapies for reducing cardiovascular risk among people with rheumatoid arthritis

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainPeople with rheumatoid arthritis are at increased risk of cardiovascular (CV) disease, with studies indicating an approximate

Updated on: May 13,2024 5

Trial compares therapies for reducing cardiovascular risk among people with rheumatoid arthritis

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainPeople with rheumatoid arthritis are at increased risk of cardiovascular (CV) disease, with studies indicating an approximate

Updated on:May 13,2024 5

Researchers validate pediatric 'allergic march' in largest national study of its kind

byChildren's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainIn the largest study of its kind, researchers from Children's Hospital of Philadelphia (CHOP) used electronic healt

Updated on: March 05,2024 2

Researchers validate pediatric 'allergic march' in largest national study of its kind

byChildren's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainIn the largest study of its kind, researchers from Children's Hospital of Philadelphia (CHOP) used electronic healt

Updated on:March 05,2024 2

Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on: March 19,2024 18

Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on:March 19,2024 18

Smoking shown to have long-term effects on the immune system

by Pasteur InstituteCredit: CC0 Public DomainLike other factors such as age, sex, and genetics, smoking has a major impact on immune responses. This is the finding recently made by a team of scie

Updated on: March 07,2024 14

Smoking shown to have long-term effects on the immune system

by Pasteur InstituteCredit: CC0 Public DomainLike other factors such as age, sex, and genetics, smoking has a major impact on immune responses. This is the finding recently made by a team of scie

Updated on:March 07,2024 14

Renal macrophages observed playing crucial role in preventing kidney stones

by Justin Jackson , Medical XpressGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.12.003Researchers at Zhejiang University School of Medicine, China, have investigate

Updated on: March 07,2024 19

Renal macrophages observed playing crucial role in preventing kidney stones

by Justin Jackson , Medical XpressGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.12.003Researchers at Zhejiang University School of Medicine, China, have investigate

Updated on:March 07,2024 19

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on: May 13,2024 3

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on:May 13,2024 3