Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on: April 28,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on:April 28,2024

Scientists pioneer immunotherapy technique for autoimmune diseases

byMayo ClinicMSCs are transduced to express CAR and maintain stem-like features following transduction and stimulation. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s4155

Updated on: April 06,2024

Scientists pioneer immunotherapy technique for autoimmune diseases

byMayo ClinicMSCs are transduced to express CAR and maintain stem-like features following transduction and stimulation. Credit:Nature Biomedical Engineering(2024). DOI: 10.1038/s4155

Updated on:April 06,2024

We are getting older and heavier, and osteoarthritis is increasing

by Lund UniversityCredit: CC0 Public DomainThe number of patients with osteoarthritis has increased dramatically since the 1950s. Along with diabetes, the illness is now one of the fastest-growin

Updated on: June 01,2024

We are getting older and heavier, and osteoarthritis is increasing

by Lund UniversityCredit: CC0 Public DomainThe number of patients with osteoarthritis has increased dramatically since the 1950s. Along with diabetes, the illness is now one of the fastest-growin

Updated on:June 01,2024

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on: May 13,2024

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on:May 13,2024

COVID-19 booster immunity lasts much longer than primary series alone, study shows

by York UniversityPrimary series and booster dose model fit results. (A) Example individual model fits for the primary series (blue) and booster dose (orange) Anti-S trajectory data. Dashed lines for

Updated on: May 14,2024

COVID-19 booster immunity lasts much longer than primary series alone, study shows

by York UniversityPrimary series and booster dose model fit results. (A) Example individual model fits for the primary series (blue) and booster dose (orange) Anti-S trajectory data. Dashed lines for

Updated on:May 14,2024

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on: May 13,2024

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on:May 13,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on: May 19,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on:May 19,2024

Multifactorial mechanisms underlie leg weakness in hip OA

Multiple factors contribute to leg weakness in people with hip osteoarthritis, with muscle atrophy being the strongest contributor, according to the results of a systematic review published online Jul

Updated on: April 08,2024

Multifactorial mechanisms underlie leg weakness in hip OA

Multiple factors contribute to leg weakness in people with hip osteoarthritis, with muscle atrophy being the strongest contributor, according to the results of a systematic review published online Jul

Updated on:April 08,2024

Gut bacteria important for overcoming milk allergy, study suggests

by RIKENThe study found that successful oral immunotherapy in children was associated with having Bifidobacterium bacteria in the gut, while unsuccessful treatment was associated with having ecze

Updated on: March 20,2024

Gut bacteria important for overcoming milk allergy, study suggests

by RIKENThe study found that successful oral immunotherapy in children was associated with having Bifidobacterium bacteria in the gut, while unsuccessful treatment was associated with having ecze

Updated on:March 20,2024

Systemic inflammation increases risk for chronic kidney disease

by Lori SolomonSystemic inflammation is associated with an elevated risk for chronic kidney disease, according to a study published online Feb. 20 inFrontiers in Immunology.Xiaoxin Liu, from Ton

Updated on: April 30,2024

Systemic inflammation increases risk for chronic kidney disease

by Lori SolomonSystemic inflammation is associated with an elevated risk for chronic kidney disease, according to a study published online Feb. 20 inFrontiers in Immunology.Xiaoxin Liu, from Ton

Updated on:April 30,2024

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on: October 26,2024

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on:October 26,2024

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on: January 26,2024

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on:January 26,2024