Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on: May 13,2024

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on:May 13,2024

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on: May 13,2024

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on:May 13,2024

Discovery of how to limit asthma attack damage could stop disease

byKing's College LondonCredit: CC0 Public DomainScientists at King's College London have discovered a new cause for asthma that sparks hope for treatment that could prevent the life-thre

Updated on: April 30,2024

Discovery of how to limit asthma attack damage could stop disease

byKing's College LondonCredit: CC0 Public DomainScientists at King's College London have discovered a new cause for asthma that sparks hope for treatment that could prevent the life-thre

Updated on:April 30,2024

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on: January 26,2024

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on:January 26,2024

The promise of precision medicine for rheumatoid arthritis

by Yale UniversityA hand affected by rheumatoid arthritis. Credit: James Heilman, MD/WikipediaIn a new study, a Yale-led research team identified the mechanism of a gene that raises the risk of s

Updated on: May 13,2024

The promise of precision medicine for rheumatoid arthritis

by Yale UniversityA hand affected by rheumatoid arthritis. Credit: James Heilman, MD/WikipediaIn a new study, a Yale-led research team identified the mechanism of a gene that raises the risk of s

Updated on:May 13,2024

Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on: March 19,2024

Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on:March 19,2024

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on: January 26,2024

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on:January 26,2024

Secondary structures in DNA are associated with cancer

by Lila Reynolds,Northwestern UniversityCredit: CC0 Public DomainA new cancer study reports that DNA manifested as knot-like folds and third rungs between DNA's two strands may drive cancer

Updated on: April 15,2024

Secondary structures in DNA are associated with cancer

by Lila Reynolds,Northwestern UniversityCredit: CC0 Public DomainA new cancer study reports that DNA manifested as knot-like folds and third rungs between DNA's two strands may drive cancer

Updated on:April 15,2024

A novel painless and reliable allergy test

byUniversity of BernCredit: CC0 Public DomainAlthough allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not al

Updated on: March 05,2024

A novel painless and reliable allergy test

byUniversity of BernCredit: CC0 Public DomainAlthough allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not al

Updated on:March 05,2024

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on: October 24,2024

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on:October 24,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on: May 19,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on:May 19,2024

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o

Updated on: April 02,2024

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o

Updated on:April 02,2024