Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on: May 13,2024 3

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on:May 13,2024 3

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on: March 25,2024 13

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on:March 25,2024 13

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on: April 09,2024 17

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on:April 09,2024 17

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on: January 26,2024 12

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on:January 26,2024 12

MAIT cells can be tuned to fight different pathogens via their metabolism, leading to new therapeutic strategies

by La Jolla Institute for ImmunologyCredit: Pixabay/CC0 Public DomainA population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike. Un

Updated on: April 20,2024 16

MAIT cells can be tuned to fight different pathogens via their metabolism, leading to new therapeutic strategies

by La Jolla Institute for ImmunologyCredit: Pixabay/CC0 Public DomainA population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike. Un

Updated on:April 20,2024 16

Mayo Clinic Q and A: Springtime allergies

by Cynthia WeissCredit: CC0 Public DomainDEAR MAYO CLINIC: I love the changing seasons and am looking forward to the warmer days of spring. Unfortunately, I am often miserable because of seasonal alle

Updated on: March 04,2024 17

Mayo Clinic Q and A: Springtime allergies

by Cynthia WeissCredit: CC0 Public DomainDEAR MAYO CLINIC: I love the changing seasons and am looking forward to the warmer days of spring. Unfortunately, I am often miserable because of seasonal alle

Updated on:March 04,2024 17

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on: March 30,2024 19

Preventing cell death as novel therapeutic strategy for rheumatoid arthritis

by VIB (the Flanders Institute for Biotechnology)Credit: CC0 Public DomainA collaborative study has identified a new molecular mechanism causing rheumatoid arthritis. The researchers found that d

Updated on:March 30,2024 19

Study links lower hydroxychloroquine dose to more hospitalizations for systemic lupus erythematosus flares

by American College of RheumatologyCase-Crossover Study Design: In this case-crossover study, case periods were the 6-months prior to a hospitalization for SLE flare. Control periods were 6-month

Updated on: June 01,2024 3

Study links lower hydroxychloroquine dose to more hospitalizations for systemic lupus erythematosus flares

by American College of RheumatologyCase-Crossover Study Design: In this case-crossover study, case periods were the 6-months prior to a hospitalization for SLE flare. Control periods were 6-month

Updated on:June 01,2024 3

Got osteoarthritis? Get moving

(HealthDay)—Is arthritis pain getting in the way of your fitness plans? That need not be the case.In fact,physical activitycan be vital to your continued mobility.Osteoarthritis is a

Updated on: April 07,2024 19

Got osteoarthritis? Get moving

(HealthDay)—Is arthritis pain getting in the way of your fitness plans? That need not be the case.In fact,physical activitycan be vital to your continued mobility.Osteoarthritis is a

Updated on:April 07,2024 19

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on: April 07,2024 16

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on:April 07,2024 16

DNA as a weapon of immune defense

by University of GenevaThis is a slug made up of social amoebae. In red are the reactive oxygen species produced by the sentinel cells, which are necessary for the generation of DNA nets that def

Updated on: April 15,2024 16

DNA as a weapon of immune defense

by University of GenevaThis is a slug made up of social amoebae. In red are the reactive oxygen species produced by the sentinel cells, which are necessary for the generation of DNA nets that def

Updated on:April 15,2024 16

'Mix and match' assembly instructions guide immune cell attacks

by Walter and Eliza Hall Institute of Medical ResearchAssociate Professor Matthew Call (left) and Dr Melissa Call discovered a unique way that immune cells respond to, and kill, diseased and canc

Updated on: March 13,2024 20

'Mix and match' assembly instructions guide immune cell attacks

by Walter and Eliza Hall Institute of Medical ResearchAssociate Professor Matthew Call (left) and Dr Melissa Call discovered a unique way that immune cells respond to, and kill, diseased and canc

Updated on:March 13,2024 20