The promise of precision medicine for rheumatoid arthritis

by Yale UniversityA hand affected by rheumatoid arthritis. Credit: James Heilman, MD/WikipediaIn a new study, a Yale-led research team identified the mechanism of a gene that raises the risk of s

Updated on: May 13,2024

The promise of precision medicine for rheumatoid arthritis

by Yale UniversityA hand affected by rheumatoid arthritis. Credit: James Heilman, MD/WikipediaIn a new study, a Yale-led research team identified the mechanism of a gene that raises the risk of s

Updated on:May 13,2024

Secondary structures in DNA are associated with cancer

by Lila Reynolds,Northwestern UniversityCredit: CC0 Public DomainA new cancer study reports that DNA manifested as knot-like folds and third rungs between DNA's two strands may drive cancer

Updated on: April 15,2024

Secondary structures in DNA are associated with cancer

by Lila Reynolds,Northwestern UniversityCredit: CC0 Public DomainA new cancer study reports that DNA manifested as knot-like folds and third rungs between DNA's two strands may drive cancer

Updated on:April 15,2024

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on: May 13,2024

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on:May 13,2024

Rehab or steroid shots: What's best for arthritic knees?

by Dennis Thompson(HealthDay)—Physical therapy for knee arthritis tends to cost patients more out-of-pocket and involves a lot more hassle than a quick steroid shot to soothe an aching joint.But in th

Updated on: May 23,2024

Rehab or steroid shots: What's best for arthritic knees?

by Dennis Thompson(HealthDay)—Physical therapy for knee arthritis tends to cost patients more out-of-pocket and involves a lot more hassle than a quick steroid shot to soothe an aching joint.But in th

Updated on:May 23,2024

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on: January 26,2024

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on:January 26,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on: May 19,2024

Teens with chronic conditions face challenges and risks when they age out of pediatric rheumatology care

by Michelle Batthish and Stephanie Garner,The ConversationCredit: AI-generated imageLiving with severeinflammatory arthritisor any other serious condition of the joints, bones and mu

Updated on:May 19,2024

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on: April 22,2024

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on:April 22,2024

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on: January 26,2024

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on:January 26,2024

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on: May 13,2024

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on:May 13,2024

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o

Updated on: April 02,2024

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o

Updated on:April 02,2024

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on: October 26,2024

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on:October 26,2024

Smoking shown to have long-term effects on the immune system

by Pasteur InstituteCredit: CC0 Public DomainLike other factors such as age, sex, and genetics, smoking has a major impact on immune responses. This is the finding recently made by a team of scie

Updated on: March 07,2024

Smoking shown to have long-term effects on the immune system

by Pasteur InstituteCredit: CC0 Public DomainLike other factors such as age, sex, and genetics, smoking has a major impact on immune responses. This is the finding recently made by a team of scie

Updated on:March 07,2024