CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on: April 09,2024 17

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

Updated on:April 09,2024 17

How mutation of the APC gene disrupts lymphocyte migration in colon cancer

by Pasteur InstituteMigrating human T lymphocytes revealing a broad protrusion at the leading edge and long adhesive protrusions at the rear. Image obtained by confocal fluorescence microscopy: f

Updated on: April 08,2024 19

How mutation of the APC gene disrupts lymphocyte migration in colon cancer

by Pasteur InstituteMigrating human T lymphocytes revealing a broad protrusion at the leading edge and long adhesive protrusions at the rear. Image obtained by confocal fluorescence microscopy: f

Updated on:April 08,2024 19

A fresh look at joint inflammation in rheumatoid arthritis patients

by Trinity College DublinCredit: Unsplash/CC0 Public DomainResearchers at Trinity are providing fresh insights into joint inflammation in patients with rheumatoid arthritis (RA). The condition cu

Updated on: June 11,2024 5

A fresh look at joint inflammation in rheumatoid arthritis patients

by Trinity College DublinCredit: Unsplash/CC0 Public DomainResearchers at Trinity are providing fresh insights into joint inflammation in patients with rheumatoid arthritis (RA). The condition cu

Updated on:June 11,2024 5

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on: April 28,2024 0

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on:April 28,2024 0

Researchers identify new way to inhibit immune cells that drive allergic asthma

by Rockefeller University PressActivation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Credit:(2024)

Updated on: April 06,2024 0

Researchers identify new way to inhibit immune cells that drive allergic asthma

by Rockefeller University PressActivation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Credit:(2024)

Updated on:April 06,2024 0

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on: May 13,2024 5

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on:May 13,2024 5

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on: January 26,2024 12

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on:January 26,2024 12

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on: October 26,2024 0

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Updated on:October 26,2024 0

No link between 'hypoallergenic' dogs and lower risk of childhood asthma

by Karolinska InstitutetCredit: CC0 Public DomainGrowing up with dogs is linked to a lower risk of asthma, especially if the dogs are female, a new study from Karolinska Institutet and Uppsala Un

Updated on: March 13,2024 15

No link between 'hypoallergenic' dogs and lower risk of childhood asthma

by Karolinska InstitutetCredit: CC0 Public DomainGrowing up with dogs is linked to a lower risk of asthma, especially if the dogs are female, a new study from Karolinska Institutet and Uppsala Un

Updated on:March 13,2024 15

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on: April 22,2024 15

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on:April 22,2024 15

Genes and cellular processes that contribute to the pathogenesis of RVVC found

by Bob Yirka , Medical XpressCandida albicans. Credit: Wikipedia.An international team of researchers has identified some of the genes and cellular processes that contribute to the pathogenesis of rec

Updated on: April 22,2024 12

Genes and cellular processes that contribute to the pathogenesis of RVVC found

by Bob Yirka , Medical XpressCandida albicans. Credit: Wikipedia.An international team of researchers has identified some of the genes and cellular processes that contribute to the pathogenesis of rec

Updated on:April 22,2024 12

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on: January 26,2024 12

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

Updated on:January 26,2024 12