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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
Latest Articles
Curbing blood cancers by teaching immune cells to kill mutant stem cells

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro
Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot

Trial shows timing matters when adding immunotherapy to chemoradiation for limited-stage small cell lung cancer

byAmerican Society for Radiation OncologyCredit: Pixabay/CC0 Public DomainPeople with limited-stage small cell lung cancer may benefit from adding immunotherapy to chemoradiation, but not if bot
Treatment effect of tofacitinib, adalimumab compared in RA

Treatment effect of tofacitinib, adalimumab compared in RA

by Elana GotkineFor adults with rheumatoid arthritis (RA), there is a modest reduction in the mean Disease Activity Score in 28 joints using C-reactive protein (DAS28-CRP) at three months for patients

Treatment effect of tofacitinib, adalimumab compared in RA

by Elana GotkineFor adults with rheumatoid arthritis (RA), there is a modest reduction in the mean Disease Activity Score in 28 joints using C-reactive protein (DAS28-CRP) at three months for patients
Study offers new insights into how immune cells recognize their enemies

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146
CAR T-cell immunotherapy rids woman of tough-to-treat lupus

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already
How mutation of the APC gene disrupts lymphocyte migration in colon cancer

How mutation of the APC gene disrupts lymphocyte migration in colon cancer

by Pasteur InstituteMigrating human T lymphocytes revealing a broad protrusion at the leading edge and long adhesive protrusions at the rear. Image obtained by confocal fluorescence microscopy: f

How mutation of the APC gene disrupts lymphocyte migration in colon cancer

by Pasteur InstituteMigrating human T lymphocytes revealing a broad protrusion at the leading edge and long adhesive protrusions at the rear. Image obtained by confocal fluorescence microscopy: f
Researchers identify new way to inhibit immune cells that drive allergic asthma

Researchers identify new way to inhibit immune cells that drive allergic asthma

by Rockefeller University PressActivation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Credit:(2024)

Researchers identify new way to inhibit immune cells that drive allergic asthma

by Rockefeller University PressActivation of ILC2s causes inflammation in mouse lungs (left), but this is reduced by treatment with Yoda1 to stimulate Piezo1 channels (right). Credit:(2024)
New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp

New study uncovers molecular interactions driving multiple inflammasome activation and inflammatory cell death

by JooHyeon Heo,Ulsan National Institute of Science and TechnologyThe formation of panoptosomes and inflammatory apoptosis following the injection of four pathogen-related patterns. Credit:&nbsp
40 percent of adolescents with food allergies experience frequent anaphylactic episodes

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o

40 percent of adolescents with food allergies experience frequent anaphylactic episodes

by Murdoch Childrens Research InstituteCredit: Murdoch Childrens Research InstituteA new study by researchers from the Murdoch Children's Research Institute (MCRI) has shown that 40 percent o
A fresh look at joint inflammation in rheumatoid arthritis patients

A fresh look at joint inflammation in rheumatoid arthritis patients

by Trinity College DublinCredit: Unsplash/CC0 Public DomainResearchers at Trinity are providing fresh insights into joint inflammation in patients with rheumatoid arthritis (RA). The condition cu

A fresh look at joint inflammation in rheumatoid arthritis patients

by Trinity College DublinCredit: Unsplash/CC0 Public DomainResearchers at Trinity are providing fresh insights into joint inflammation in patients with rheumatoid arthritis (RA). The condition cu
No link between 'hypoallergenic' dogs and lower risk of childhood asthma

No link between 'hypoallergenic' dogs and lower risk of childhood asthma

by Karolinska InstitutetCredit: CC0 Public DomainGrowing up with dogs is linked to a lower risk of asthma, especially if the dogs are female, a new study from Karolinska Institutet and Uppsala Un

No link between 'hypoallergenic' dogs and lower risk of childhood asthma

by Karolinska InstitutetCredit: CC0 Public DomainGrowing up with dogs is linked to a lower risk of asthma, especially if the dogs are female, a new study from Karolinska Institutet and Uppsala Un
Systemic inflammation increases risk for chronic kidney disease

Systemic inflammation increases risk for chronic kidney disease

by Lori SolomonSystemic inflammation is associated with an elevated risk for chronic kidney disease, according to a study published online Feb. 20 inFrontiers in Immunology.Xiaoxin Liu, from Ton

Systemic inflammation increases risk for chronic kidney disease

by Lori SolomonSystemic inflammation is associated with an elevated risk for chronic kidney disease, according to a study published online Feb. 20 inFrontiers in Immunology.Xiaoxin Liu, from Ton