Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on: October 24,2024

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on:October 24,2024

Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

by The Reis GroupCredit: Pixabay/CC0 Public DomainGenicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduc

Updated on: May 23,2024

Non-surgical treatment significantly reduces knee pain for adults, especially those 50 and older

by The Reis GroupCredit: Pixabay/CC0 Public DomainGenicular nerve radiofrequency ablation is a minimally invasive treatment for knee pain due to osteoarthritis of the knee, and can significantly reduc

Updated on:May 23,2024

COVID-19 booster immunity lasts much longer than primary series alone, study shows

by York UniversityPrimary series and booster dose model fit results. (A) Example individual model fits for the primary series (blue) and booster dose (orange) Anti-S trajectory data. Dashed lines for

Updated on: May 14,2024

COVID-19 booster immunity lasts much longer than primary series alone, study shows

by York UniversityPrimary series and booster dose model fit results. (A) Example individual model fits for the primary series (blue) and booster dose (orange) Anti-S trajectory data. Dashed lines for

Updated on:May 14,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on: April 28,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on:April 28,2024

Research shows mRNA vaccination is safe and effective, even with chronic inflammatory diseases

by Kiel UniversityCredit: PixabayChronic inflammatory diseases, such as rheumatic diseases, psoriasis or chronic inflammatory bowel diseases are autoimmune diseases in which the immune system tar

Updated on: May 13,2024

Research shows mRNA vaccination is safe and effective, even with chronic inflammatory diseases

by Kiel UniversityCredit: PixabayChronic inflammatory diseases, such as rheumatic diseases, psoriasis or chronic inflammatory bowel diseases are autoimmune diseases in which the immune system tar

Updated on:May 13,2024

How T cells recognize infection or disease

by Monash UniversityResearch illuminating an elusive component of the adaptive immune system, how gamma delta T cells sense the metabolite-antigen presenting molecule MR1. Credit: (C) Dr Erica Ta

Updated on: April 24,2024

How T cells recognize infection or disease

by Monash UniversityResearch illuminating an elusive component of the adaptive immune system, how gamma delta T cells sense the metabolite-antigen presenting molecule MR1. Credit: (C) Dr Erica Ta

Updated on:April 24,2024

Sleep deprivation may increase risk for systemic lupus in women

Lack of sleep is associated with an increased risk for systemic lupus erythematosus (SLE), particularly among women with concomitant depression or bodily pain, according to a study published online Se

Updated on: May 26,2024

Sleep deprivation may increase risk for systemic lupus in women

Lack of sleep is associated with an increased risk for systemic lupus erythematosus (SLE), particularly among women with concomitant depression or bodily pain, according to a study published online Se

Updated on:May 26,2024

Study finds lower risk of severe infection and hospitalization with belimumab compared to oral immunosuppressants

by American College of RheumatologyComparative Risk of Severe Infection and Hospitalizations for Severe Infections with Belimumab versus Oral Immunosuppressants. Hazard ratios and 95% confidence

Updated on: June 06,2024

Study finds lower risk of severe infection and hospitalization with belimumab compared to oral immunosuppressants

by American College of RheumatologyComparative Risk of Severe Infection and Hospitalizations for Severe Infections with Belimumab versus Oral Immunosuppressants. Hazard ratios and 95% confidence

Updated on:June 06,2024

How an immune response is driven by one letter difference in DNA

byRadboud UniversityA biphasic circuit regulates IL-1β and IL-37 expression to coordinate pro- and anti-inflammatory processes from within a single TAD. The two functionally opposed states of th

Updated on: January 26,2024

How an immune response is driven by one letter difference in DNA

byRadboud UniversityA biphasic circuit regulates IL-1β and IL-37 expression to coordinate pro- and anti-inflammatory processes from within a single TAD. The two functionally opposed states of th

Updated on:January 26,2024

First-degree relatives have high perceived risk for rheumatoid arthritis

by Elana GotkineFirst-degree relatives (FDRs) of patients with rheumatoid arthritis (RA) have a high perceived risk for developing RA, according to a study published online Dec. 5 inRMD Open.Sar

Updated on: June 26,2024

First-degree relatives have high perceived risk for rheumatoid arthritis

by Elana GotkineFirst-degree relatives (FDRs) of patients with rheumatoid arthritis (RA) have a high perceived risk for developing RA, according to a study published online Dec. 5 inRMD Open.Sar

Updated on:June 26,2024

COVID-19 unmasked: Math model suggests optimal treatment strategies

by Massachusetts General HospitalColorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Ima

Updated on: April 10,2024

COVID-19 unmasked: Math model suggests optimal treatment strategies

by Massachusetts General HospitalColorized scanning electron micrograph of an apoptotic cell (green) heavily infected with SARS-COV-2 virus particles (yellow), isolated from a patient sample. Ima

Updated on:April 10,2024

Key features of chronic nonbacterial osteomyelitis identified in groundbreaking study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, identified key clinical features

Updated on: May 23,2024

Key features of chronic nonbacterial osteomyelitis identified in groundbreaking study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, identified key clinical features

Updated on:May 23,2024