How an immune response is driven by one letter difference in DNA

byRadboud UniversityA biphasic circuit regulates IL-1β and IL-37 expression to coordinate pro- and anti-inflammatory processes from within a single TAD. The two functionally opposed states of th

Updated on: January 26,2024

How an immune response is driven by one letter difference in DNA

byRadboud UniversityA biphasic circuit regulates IL-1β and IL-37 expression to coordinate pro- and anti-inflammatory processes from within a single TAD. The two functionally opposed states of th

Updated on:January 26,2024

Antihistamines can be helpful during spring allergy season and as COVID vaccines roll out, for which rashes are common

byMcMaster UniversityCredit: Pixabay/CC0 Public DomainIf you are one of the millions of people worldwide suffering from allergies, you may take an antihistamine pill to ward off hives, sneezing

Updated on: March 02,2024

Antihistamines can be helpful during spring allergy season and as COVID vaccines roll out, for which rashes are common

byMcMaster UniversityCredit: Pixabay/CC0 Public DomainIf you are one of the millions of people worldwide suffering from allergies, you may take an antihistamine pill to ward off hives, sneezing

Updated on:March 02,2024

CARv3-TEAM-E T-cell treatment beneficial for recurrent glioblastoma

by Elana GotkineFor patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-spec

Updated on: March 27,2024

CARv3-TEAM-E T-cell treatment beneficial for recurrent glioblastoma

by Elana GotkineFor patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-spec

Updated on:March 27,2024

Trials bring hope for world–first rheumatoid arthritis treatment

by University of QueenslandUQ’s Diamantina Institute Professor Ranjeny Thomas. Credit: University of QueenslandHuman trials of an innovative treatment for rheumatoid arthritis developed by The Un

Updated on: March 24,2024

Trials bring hope for world–first rheumatoid arthritis treatment

by University of QueenslandUQ’s Diamantina Institute Professor Ranjeny Thomas. Credit: University of QueenslandHuman trials of an innovative treatment for rheumatoid arthritis developed by The Un

Updated on:March 24,2024

Rehab or steroid shots: What's best for arthritic knees?

by Dennis Thompson(HealthDay)—Physical therapy for knee arthritis tends to cost patients more out-of-pocket and involves a lot more hassle than a quick steroid shot to soothe an aching joint.But in th

Updated on: May 23,2024

Rehab or steroid shots: What's best for arthritic knees?

by Dennis Thompson(HealthDay)—Physical therapy for knee arthritis tends to cost patients more out-of-pocket and involves a lot more hassle than a quick steroid shot to soothe an aching joint.But in th

Updated on:May 23,2024

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on: October 24,2024

Curbing blood cancers by teaching immune cells to kill mutant stem cells

by Nancy Fliesler,Children's Hospital BostonROS and TLR3 signaling mediates the "eat-me" and "don't eat me" signals that determine stem cell clonal selection by macro

Updated on:October 24,2024

First-degree relatives have high perceived risk for rheumatoid arthritis

by Elana GotkineFirst-degree relatives (FDRs) of patients with rheumatoid arthritis (RA) have a high perceived risk for developing RA, according to a study published online Dec. 5 inRMD Open.Sar

Updated on: June 26,2024

First-degree relatives have high perceived risk for rheumatoid arthritis

by Elana GotkineFirst-degree relatives (FDRs) of patients with rheumatoid arthritis (RA) have a high perceived risk for developing RA, according to a study published online Dec. 5 inRMD Open.Sar

Updated on:June 26,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on: April 28,2024

Successful murine model of dermatomyositis reveals underlying immune system involvement

byTokyo Medical and Dental UniversityAutoimmunity to MDA5, CD4 T cells reactive MDA5, works as 'Seed', and inducible factors like as virus infection and poly (I:C) treatment induce type

Updated on:April 28,2024

Study links lower hydroxychloroquine dose to more hospitalizations for systemic lupus erythematosus flares

by American College of RheumatologyCase-Crossover Study Design: In this case-crossover study, case periods were the 6-months prior to a hospitalization for SLE flare. Control periods were 6-month

Updated on: June 01,2024

Study links lower hydroxychloroquine dose to more hospitalizations for systemic lupus erythematosus flares

by American College of RheumatologyCase-Crossover Study Design: In this case-crossover study, case periods were the 6-months prior to a hospitalization for SLE flare. Control periods were 6-month

Updated on:June 01,2024

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on: January 26,2024

Study offers new insights into how immune cells recognize their enemies

by Gunnar Bartsch,Julius-Maximilians-Universität WürzburgPAg induced Vγ9Vδ2 T cell activation by BTN3A-BTN2A1 composite ligand. Credit:Nature Communications(2023). DOI: 10.1038/s4146

Updated on:January 26,2024

Key features of chronic nonbacterial osteomyelitis identified in groundbreaking study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, identified key clinical features

Updated on: May 23,2024

Key features of chronic nonbacterial osteomyelitis identified in groundbreaking study

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, identified key clinical features

Updated on:May 23,2024

Developing an antibody to combat age-related muscle atrophy

byKyushu UniversityHGF nitration disrupts muscle homeostasis as an organism age. The new rat anti-HGF monoclonal antibody the research team developed, called 1H41C10, specially binds to the nitr

Updated on: November 24,2024

Developing an antibody to combat age-related muscle atrophy

byKyushu UniversityHGF nitration disrupts muscle homeostasis as an organism age. The new rat anti-HGF monoclonal antibody the research team developed, called 1H41C10, specially binds to the nitr

Updated on:November 24,2024