Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on: May 13,2024 5

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on:May 13,2024 5

MAIT cells can be tuned to fight different pathogens via their metabolism, leading to new therapeutic strategies

by La Jolla Institute for ImmunologyCredit: Pixabay/CC0 Public DomainA population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike. Un

Updated on: April 20,2024 16

MAIT cells can be tuned to fight different pathogens via their metabolism, leading to new therapeutic strategies

by La Jolla Institute for ImmunologyCredit: Pixabay/CC0 Public DomainA population of unconventional white blood cells has recently captured the attention of immunologists and clinicians alike. Un

Updated on:April 20,2024 16

Tezepelumab significantly reduced asthma exacerbations: Phase 3 NAVIGATOR trial

by American Thoracic SocietyObstruction of the lumen of a bronchiole by mucoid exudate, goblet cell metaplasia, and epithelial basement membrane thickening in a person with asthma. Credit: Yale R

Updated on: May 08,2024 5

Tezepelumab significantly reduced asthma exacerbations: Phase 3 NAVIGATOR trial

by American Thoracic SocietyObstruction of the lumen of a bronchiole by mucoid exudate, goblet cell metaplasia, and epithelial basement membrane thickening in a person with asthma. Credit: Yale R

Updated on:May 08,2024 5

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on: April 22,2024 15

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on:April 22,2024 15

Gut bacteria important for overcoming milk allergy, study suggests

by RIKENThe study found that successful oral immunotherapy in children was associated with having Bifidobacterium bacteria in the gut, while unsuccessful treatment was associated with having ecze

Updated on: March 20,2024 18

Gut bacteria important for overcoming milk allergy, study suggests

by RIKENThe study found that successful oral immunotherapy in children was associated with having Bifidobacterium bacteria in the gut, while unsuccessful treatment was associated with having ecze

Updated on:March 20,2024 18

Personalized 3D-printed knee implant could help thousands of arthritis sufferers

by University of BathThe bespoke implant preserves the existing joint and can be used at an earlier stage of arthritis, before a knee replacement is needed. Credit: University of BathA groundbrea

Updated on: May 13,2024 4

Personalized 3D-printed knee implant could help thousands of arthritis sufferers

by University of BathThe bespoke implant preserves the existing joint and can be used at an earlier stage of arthritis, before a knee replacement is needed. Credit: University of BathA groundbrea

Updated on:May 13,2024 4

Developing an antibody to combat age-related muscle atrophy

byKyushu UniversityHGF nitration disrupts muscle homeostasis as an organism age. The new rat anti-HGF monoclonal antibody the research team developed, called 1H41C10, specially binds to the nitr

Updated on: November 24,2024 0

Developing an antibody to combat age-related muscle atrophy

byKyushu UniversityHGF nitration disrupts muscle homeostasis as an organism age. The new rat anti-HGF monoclonal antibody the research team developed, called 1H41C10, specially binds to the nitr

Updated on:November 24,2024 0

Updated recommendations for psoriatic arthritis

by European Alliance of Associations for Rheumatology, EULARCredit: Unsplash/CC0 Public DomainPsoriatic arthritis (PsA) is an autoimmune inflammatory disease. It has both joint and non-joint symptoms

Updated on: March 27,2024 0

Updated recommendations for psoriatic arthritis

by European Alliance of Associations for Rheumatology, EULARCredit: Unsplash/CC0 Public DomainPsoriatic arthritis (PsA) is an autoimmune inflammatory disease. It has both joint and non-joint symptoms

Updated on:March 27,2024 0

Study links early TNF inhibitor treatment to higher heart disease risk in ankylosing spondylitis patients, with caveats

by American College of RheumatologyCredit: Jean Liew et al, The Association of Early TNF Inhibitor Use with Incident Cardiovascular Events in Ankylosing Spondylitis [abstract]. Arthritis Rheumato

Updated on: June 15,2024 7

Study links early TNF inhibitor treatment to higher heart disease risk in ankylosing spondylitis patients, with caveats

by American College of RheumatologyCredit: Jean Liew et al, The Association of Early TNF Inhibitor Use with Incident Cardiovascular Events in Ankylosing Spondylitis [abstract]. Arthritis Rheumato

Updated on:June 15,2024 7

Knee problems tend to flare up as you age—an orthopedic specialist explains available treatment options

by Angie Brown,The ConversationCredit: CC0 Public DomainKnee injuries are common in athletes, accounting for41% of all athletic injuries. But knee injuries aren't limited to competitiv

Updated on: November 21,2024 0

Knee problems tend to flare up as you age—an orthopedic specialist explains available treatment options

by Angie Brown,The ConversationCredit: CC0 Public DomainKnee injuries are common in athletes, accounting for41% of all athletic injuries. But knee injuries aren't limited to competitiv

Updated on:November 21,2024 0

Scientists discover a rare missense variant in STAT6 that protects against asthma

by deCODE geneticsp.L406P is a partial LOF variant. Credit:Journal of Allergy and Clinical Immunology(2024). DOI: 10.1016/j.jaci.2024.10.002Scientists at deCODE genetics and collaborators

Updated on: November 22,2024 0

Scientists discover a rare missense variant in STAT6 that protects against asthma

by deCODE geneticsp.L406P is a partial LOF variant. Credit:Journal of Allergy and Clinical Immunology(2024). DOI: 10.1016/j.jaci.2024.10.002Scientists at deCODE genetics and collaborators

Updated on:November 22,2024 0

'Mix and match' assembly instructions guide immune cell attacks

by Walter and Eliza Hall Institute of Medical ResearchAssociate Professor Matthew Call (left) and Dr Melissa Call discovered a unique way that immune cells respond to, and kill, diseased and canc

Updated on: March 13,2024 20

'Mix and match' assembly instructions guide immune cell attacks

by Walter and Eliza Hall Institute of Medical ResearchAssociate Professor Matthew Call (left) and Dr Melissa Call discovered a unique way that immune cells respond to, and kill, diseased and canc

Updated on:March 13,2024 20