An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on: March 07,2024 19

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on:March 07,2024 19

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on: March 07,2024 18

Study shows genetically modified pluripotent stem cells may evade immunological rejection after transplantation

by University of ArizonaGeneration of an HLA-I/II and MICA/B-deficient hESC line (A) Representation of the Cas9 editing strategy. Wild-type H1 hESCs were transfected with a Cas9 construct and up

Updated on:March 07,2024 18

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on: April 22,2024 20

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on:April 22,2024 20

10 percent of US adults physically limited by arthritis, CDC reports

by Steven Reinberg, Healthday ReporterExperts say obesity epidemic has widened the pool of disabled.(HealthDay)—More than 50 million Americans have arthritis, and almost half of them can't perform

Updated on: March 24,2024 16

10 percent of US adults physically limited by arthritis, CDC reports

by Steven Reinberg, Healthday ReporterExperts say obesity epidemic has widened the pool of disabled.(HealthDay)—More than 50 million Americans have arthritis, and almost half of them can't perform

Updated on:March 24,2024 16

Treatment before patients develop rheumatism provides lasting relief

by Leiden University Medical CentreCredit: Unsplash/CC0 Public DomainInitiating early treatment benefits patients who have not fully developed rheumatoid arthritis, but who are manifesting preliminary

Updated on: March 30,2024 10

Treatment before patients develop rheumatism provides lasting relief

by Leiden University Medical CentreCredit: Unsplash/CC0 Public DomainInitiating early treatment benefits patients who have not fully developed rheumatoid arthritis, but who are manifesting preliminary

Updated on:March 30,2024 10

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr

Updated on: June 06,2024 6

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr

Updated on:June 06,2024 6

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on: May 13,2024 3

Rejuvenation of aging cells helps to cure osteoarthritis through gene therapy

by Chinese Academy of SciencesCBX4 maintains nucleolar homeostasis, alleviates senescence and osteoarthritis. Credit: IOZAging is a risk factor for the development of osteoarthritis (OA), a chron

Updated on:May 13,2024 3

A novel painless and reliable allergy test

byUniversity of BernCredit: CC0 Public DomainAlthough allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not al

Updated on: March 05,2024 12

A novel painless and reliable allergy test

byUniversity of BernCredit: CC0 Public DomainAlthough allergies are widespread, their diagnosis is complex and, depending on the type of allergy, the prospects of success with therapy are not al

Updated on:March 05,2024 12

Researchers validate pediatric 'allergic march' in largest national study of its kind

byChildren's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainIn the largest study of its kind, researchers from Children's Hospital of Philadelphia (CHOP) used electronic healt

Updated on: March 05,2024 2

Researchers validate pediatric 'allergic march' in largest national study of its kind

byChildren's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainIn the largest study of its kind, researchers from Children's Hospital of Philadelphia (CHOP) used electronic healt

Updated on:March 05,2024 2

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on: May 19,2024 3

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on:May 19,2024 3

Skin must develop tolerance to 'good' bacteria early in life, says new study

by Pete Farley,University of California, San FranciscoHuman skin structure. Credit: WikipediaA wave of specialized immune cells entering the skin in early life may induce tolerance to the hundre

Updated on: April 24,2024 11

Skin must develop tolerance to 'good' bacteria early in life, says new study

by Pete Farley,University of California, San FranciscoHuman skin structure. Credit: WikipediaA wave of specialized immune cells entering the skin in early life may induce tolerance to the hundre

Updated on:April 24,2024 11

Home-based phototherapy as effective as office-based for psoriasis

by Elana GotkineFor plaque or guttate psoriasis, home-based narrowband ultraviolet B phototherapy is as effective as office-based phototherapy, according to a study published online Sept. 25 inJ

Updated on: November 12,2024 0

Home-based phototherapy as effective as office-based for psoriasis

by Elana GotkineFor plaque or guttate psoriasis, home-based narrowband ultraviolet B phototherapy is as effective as office-based phototherapy, according to a study published online Sept. 25 inJ

Updated on:November 12,2024 0