How T cells recognize infection or disease

by Monash UniversityResearch illuminating an elusive component of the adaptive immune system, how gamma delta T cells sense the metabolite-antigen presenting molecule MR1. Credit: (C) Dr Erica Ta

Updated on: April 24,2024 15

How T cells recognize infection or disease

by Monash UniversityResearch illuminating an elusive component of the adaptive immune system, how gamma delta T cells sense the metabolite-antigen presenting molecule MR1. Credit: (C) Dr Erica Ta

Updated on:April 24,2024 15

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on: January 26,2024 13

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on:January 26,2024 13

Gut bacteria can process dietary fiber into an anti-allergy weapon, finds new study

by Tokyo University of ScienceGut bacteria break down dietary fiber into short-chain fatty acids, which are known to affect our immune system. In this study, researchers investigated in detail th

Updated on: March 07,2024 6

Gut bacteria can process dietary fiber into an anti-allergy weapon, finds new study

by Tokyo University of ScienceGut bacteria break down dietary fiber into short-chain fatty acids, which are known to affect our immune system. In this study, researchers investigated in detail th

Updated on:March 07,2024 6

Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses

byUniversity of CambridgeBiochemist Professor Anne Willis and immunologist Dr James Thaventhiran at the MRC Toxicology Unit at the University of Cambridge led this work. Credit: Mike Thornton, S

Updated on: January 26,2024 17

Researchers redesign future mRNA therapeutics to prevent potentially harmful immune responses

byUniversity of CambridgeBiochemist Professor Anne Willis and immunologist Dr James Thaventhiran at the MRC Toxicology Unit at the University of Cambridge led this work. Credit: Mike Thornton, S

Updated on:January 26,2024 17

Study reveals way to predict side-effect risk from common immune suppressant medication

by University of NottinghamMethotrexate (MTX) is an anti-metabolite most commonly used in chemotherapy and immunosuppressant in auto-immune diseases. Credit: University of NottinghamA major new s

Updated on: January 29,2024 13

Study reveals way to predict side-effect risk from common immune suppressant medication

by University of NottinghamMethotrexate (MTX) is an anti-metabolite most commonly used in chemotherapy and immunosuppressant in auto-immune diseases. Credit: University of NottinghamA major new s

Updated on:January 29,2024 13

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on: April 22,2024 15

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on:April 22,2024 15

Why some people with rheumatoid arthritis have pain without inflammation

by Katherine Fenz,Rockefeller UniversityIn this image (also on the cover of Science Translational Medicine), abnormal synovial tissue is shot through with excessive tissue growth, including bloo

Updated on: April 27,2024 0

Why some people with rheumatoid arthritis have pain without inflammation

by Katherine Fenz,Rockefeller UniversityIn this image (also on the cover of Science Translational Medicine), abnormal synovial tissue is shot through with excessive tissue growth, including bloo

Updated on:April 27,2024 0

SIV shrugs off antibodies in vaccinated monkeys

by Emory UniversityNew research on monkeys vaccinated against HIV's relative SIV calls into question an idea that has driven AIDS vaccine work for years. The assumption: a protective vaccine

Updated on: April 22,2024 11

SIV shrugs off antibodies in vaccinated monkeys

by Emory UniversityNew research on monkeys vaccinated against HIV's relative SIV calls into question an idea that has driven AIDS vaccine work for years. The assumption: a protective vaccine

Updated on:April 22,2024 11

Researchers show that an influx of water and salts propel immune cells through the body

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainResearchers at the Francis Crick Institute, working with Imperial College London, King's College London and University of Cambri

Updated on: January 25,2024 15

Researchers show that an influx of water and salts propel immune cells through the body

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainResearchers at the Francis Crick Institute, working with Imperial College London, King's College London and University of Cambri

Updated on:January 25,2024 15

Potential treatment for rare autoimmune disorder could be adapted from CAR-T therapy, suggests clinical trial

by National Institutes of HealthColorized scanning electron micrograph of a T lymphocyte (also known as a T cell) (blue). Credit: NIAIDEvidence from a small-scale clinical trial suggests that a v

Updated on: May 08,2024 6

Potential treatment for rare autoimmune disorder could be adapted from CAR-T therapy, suggests clinical trial

by National Institutes of HealthColorized scanning electron micrograph of a T lymphocyte (also known as a T cell) (blue). Credit: NIAIDEvidence from a small-scale clinical trial suggests that a v

Updated on:May 08,2024 6

Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on: March 19,2024 13

Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on:March 19,2024 13

Research shows that being overweight hampers the body's immune response to SARS-CoV-2

byUniversity of QueenslandCredit: Unsplash/CC0 Public DomainUniversity of Queensland-led research shows being overweight can impair the body's antibody response to SARS-CoV-2 infection but n

Updated on: January 25,2024 17

Research shows that being overweight hampers the body's immune response to SARS-CoV-2

byUniversity of QueenslandCredit: Unsplash/CC0 Public DomainUniversity of Queensland-led research shows being overweight can impair the body's antibody response to SARS-CoV-2 infection but n

Updated on:January 25,2024 17