CRISPR screen identifies new anti-inflammatory drug target

by Vanderbilt University Medical CenterCredit: CC0 Public DomainA metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inf

Updated on: April 12,2024

CRISPR screen identifies new anti-inflammatory drug target

by Vanderbilt University Medical CenterCredit: CC0 Public DomainA metabolic enzyme that has been studied in cancer biology and is important for T cell function may offer a new target for anti-inf

Updated on:April 12,2024

Study reveals way to predict side-effect risk from common immune suppressant medication

by University of NottinghamMethotrexate (MTX) is an anti-metabolite most commonly used in chemotherapy and immunosuppressant in auto-immune diseases. Credit: University of NottinghamA major new s

Updated on: January 29,2024

Study reveals way to predict side-effect risk from common immune suppressant medication

by University of NottinghamMethotrexate (MTX) is an anti-metabolite most commonly used in chemotherapy and immunosuppressant in auto-immune diseases. Credit: University of NottinghamA major new s

Updated on:January 29,2024

Parents scrambling after asthma inhaler Flovent removed from market

by Dennis ThompsonA popular asthma inhaler was discontinued on Jan. 1, and the business move has left families scrambling to find a replacement for their kids.Flovent was one of the most commonly pres

Updated on: April 23,2024

Parents scrambling after asthma inhaler Flovent removed from market

by Dennis ThompsonA popular asthma inhaler was discontinued on Jan. 1, and the business move has left families scrambling to find a replacement for their kids.Flovent was one of the most commonly pres

Updated on:April 23,2024

Canadian wildfire smoke associated with increased asthma cases in NYC

by Elizabeth Lin,Yale UniversityCredit: Yale UniversityWith smoke from Canadian wildfires once againdescending on the Northeastern United States,residents of New England and New York

Updated on: January 29,2024

Canadian wildfire smoke associated with increased asthma cases in NYC

by Elizabeth Lin,Yale UniversityCredit: Yale UniversityWith smoke from Canadian wildfires once againdescending on the Northeastern United States,residents of New England and New York

Updated on:January 29,2024

CRISPR reveals the secret life of antimicrobial peptides

by Ecole Polytechnique Federale de LausanneFruit flies with mutated antimicrobial peptides (red eyes) let bacteria (green fluorescence) grow out of control, while wild-type flies (with normal ant

Updated on: April 12,2024

CRISPR reveals the secret life of antimicrobial peptides

by Ecole Polytechnique Federale de LausanneFruit flies with mutated antimicrobial peptides (red eyes) let bacteria (green fluorescence) grow out of control, while wild-type flies (with normal ant

Updated on:April 12,2024

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on: April 22,2024

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on:April 22,2024

Can science take the STING out of runaway inflammation?

by Cincinnati Children's Hospital Medical CenterGraphical abstract. Credit:Cell Reportsand Cincinnati Children'sUntil the COVID-19 pandemic exploded, few people outside of res

Updated on: January 29,2024

Can science take the STING out of runaway inflammation?

by Cincinnati Children's Hospital Medical CenterGraphical abstract. Credit:Cell Reportsand Cincinnati Children'sUntil the COVID-19 pandemic exploded, few people outside of res

Updated on:January 29,2024

Medication used to control blood sugar in people with type 2 diabetes may also reduce risk of autoimmune diseases

by American College of RheumatologyDipeptidyl peptidase-4 inhibitors commonly used to control blood sugar levels in people with type 2 diabetes may also reduce the risk of autoimmune diseases in these

Updated on: April 07,2024

Medication used to control blood sugar in people with type 2 diabetes may also reduce risk of autoimmune diseases

by American College of RheumatologyDipeptidyl peptidase-4 inhibitors commonly used to control blood sugar levels in people with type 2 diabetes may also reduce the risk of autoimmune diseases in these

Updated on:April 07,2024

Updated guidelines released for management of atopic dermatitis

by Elana GotkineIn updated guidelines issued by the American Academy of Allergy, Asthma and Immunology/American College of Allergy, Asthma and Immunology, and published online Dec. 17 in theAnna

Updated on: January 26,2024

Updated guidelines released for management of atopic dermatitis

by Elana GotkineIn updated guidelines issued by the American Academy of Allergy, Asthma and Immunology/American College of Allergy, Asthma and Immunology, and published online Dec. 17 in theAnna

Updated on:January 26,2024

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on: January 26,2024

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on:January 26,2024

Study finds TNF blockers are not associated with poor pregnancy outcomes

byAmerican College of RheumatologyCredit: Pixabay/CC0 Public DomainAccording tonew researchatACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeti

Updated on: February 18,2024

Study finds TNF blockers are not associated with poor pregnancy outcomes

byAmerican College of RheumatologyCredit: Pixabay/CC0 Public DomainAccording tonew researchatACR Convergence 2023, the American College of Rheumatology's (ACR) annual meeti

Updated on:February 18,2024

Research explores environmental pollutant BPA and asthma susceptibility in mice

by PNAS NexusTransmission electron microscopy images demonstrating the effects of BPA on E. coli LPS. Credit: Wang et al.The "hygiene hypothesis" posits that allergic asthma can be triggered

Updated on: January 28,2024

Research explores environmental pollutant BPA and asthma susceptibility in mice

by PNAS NexusTransmission electron microscopy images demonstrating the effects of BPA on E. coli LPS. Credit: Wang et al.The "hygiene hypothesis" posits that allergic asthma can be triggered

Updated on:January 28,2024