Scientists solve 18-year-old mystery and find the once-elusive source of a critical T cell population

by Delthia Ricks , Medical XpressPresence of Tcf7+CD8+T cells during the primary response to infection. (A) Experimental schematic: Naïve P14 cells (CD45.2) were transferred into congenica

Updated on: January 26,2024 17

Scientists solve 18-year-old mystery and find the once-elusive source of a critical T cell population

by Delthia Ricks , Medical XpressPresence of Tcf7+CD8+T cells during the primary response to infection. (A) Experimental schematic: Naïve P14 cells (CD45.2) were transferred into congenica

Updated on:January 26,2024 17

Mathematical dermatology: Unraveling the mechanism of urticaria from eruption shapes

by Institute for the Advanced Study of Human Biology (ASHBI)In vivo pathophysiological network of chronic spontaneous urticaria (CSU). Credit:Communications Medicine(2023). DOI: 10.1038/s4

Updated on: January 26,2024 22

Mathematical dermatology: Unraveling the mechanism of urticaria from eruption shapes

by Institute for the Advanced Study of Human Biology (ASHBI)In vivo pathophysiological network of chronic spontaneous urticaria (CSU). Credit:Communications Medicine(2023). DOI: 10.1038/s4

Updated on:January 26,2024 22

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on: January 26,2024 13

Review highlights the challenges and recent advances in targeted therapies for lupus nephritis

by Cactus CommunicationsSLE involves abnormal activation of both innate and adaptive immune responses, leading to systemic immune dysregulation and renal impairment. The complement system's dysfun

Updated on:January 26,2024 13

Study examines the course of back pain over time

by WileyCredit: CC0 Public DomainBack pain is among the most frequently reported health problems in the world. New research published inArthritis Care & Research, an official journal of

Updated on: June 01,2024 6

Study examines the course of back pain over time

by WileyCredit: CC0 Public DomainBack pain is among the most frequently reported health problems in the world. New research published inArthritis Care & Research, an official journal of

Updated on:June 01,2024 6

Researchers show that an influx of water and salts propel immune cells through the body

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainResearchers at the Francis Crick Institute, working with Imperial College London, King's College London and University of Cambri

Updated on: January 25,2024 15

Researchers show that an influx of water and salts propel immune cells through the body

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainResearchers at the Francis Crick Institute, working with Imperial College London, King's College London and University of Cambri

Updated on:January 25,2024 15

RNA sequencing used to discover novel genes and pathways in celiac disease

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers at the Mucosal Immunology and Biology Research Center at MassGeneral Hospital for Children (MGHfC) have discovered novel gene

Updated on: April 22,2024 15

RNA sequencing used to discover novel genes and pathways in celiac disease

by Massachusetts General HospitalCredit: CC0 Public DomainResearchers at the Mucosal Immunology and Biology Research Center at MassGeneral Hospital for Children (MGHfC) have discovered novel gene

Updated on:April 22,2024 15

Atopic dermatitis in children tied to learning, memory difficulties

by Lori SolomonPediatric atopic dermatitis (AD) is associated with greater odds of reported difficulties in learning and memory, but this association is driven by children with neurodevelopmental como

Updated on: March 20,2024 20

Atopic dermatitis in children tied to learning, memory difficulties

by Lori SolomonPediatric atopic dermatitis (AD) is associated with greater odds of reported difficulties in learning and memory, but this association is driven by children with neurodevelopmental como

Updated on:March 20,2024 20

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on: April 22,2024 20

The double face of RNase as a treatment for systemic autoimmune diseases

by Osaka UniversityThe RNA-degrading enzyme enhances the function of immune complexes formed by autoantibodies against Ro/SSA and La/SSB antigens. Credit: Ryota Naito et al. JCI Insight 2023Syste

Updated on:April 22,2024 20

Epigenetics is of critical importance in autoimmune-related skin diseases, says study

by Higher Education PressCredit: Lingyu Gao, Qianjin LuThe central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product p

Updated on: March 27,2024 0

Epigenetics is of critical importance in autoimmune-related skin diseases, says study

by Higher Education PressCredit: Lingyu Gao, Qianjin LuThe central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product p

Updated on:March 27,2024 0

Study finds lower risk of severe infection and hospitalization with belimumab compared to oral immunosuppressants

by American College of RheumatologyComparative Risk of Severe Infection and Hospitalizations for Severe Infections with Belimumab versus Oral Immunosuppressants. Hazard ratios and 95% confidence

Updated on: June 06,2024 3

Study finds lower risk of severe infection and hospitalization with belimumab compared to oral immunosuppressants

by American College of RheumatologyComparative Risk of Severe Infection and Hospitalizations for Severe Infections with Belimumab versus Oral Immunosuppressants. Hazard ratios and 95% confidence

Updated on:June 06,2024 3

Snapshot turns T cell immunology on its head

by Monash UniversityChallenging a universally accepted, longstanding consensus in the field of immunity requires hard evidence. New research from the Australian Research Council Centre of excelle

Updated on: April 22,2024 20

Snapshot turns T cell immunology on its head

by Monash UniversityChallenging a universally accepted, longstanding consensus in the field of immunity requires hard evidence. New research from the Australian Research Council Centre of excelle

Updated on:April 22,2024 20

New genetic risk factors for rheumatoid arthritis revealed by analysis of multiple ancestry groups

by RIKENEnrichment of high PIP variants within open chromatin regions of 18 blood cell populations was analyzed by gchromVAR software. The horizontal dashed line indicates Bonferroni corrected P

Updated on: May 26,2024 6

New genetic risk factors for rheumatoid arthritis revealed by analysis of multiple ancestry groups

by RIKENEnrichment of high PIP variants within open chromatin regions of 18 blood cell populations was analyzed by gchromVAR software. The horizontal dashed line indicates Bonferroni corrected P

Updated on:May 26,2024 6