The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024 20

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024 20

Trial compares therapies for reducing cardiovascular risk among people with rheumatoid arthritis

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainPeople with rheumatoid arthritis are at increased risk of cardiovascular (CV) disease, with studies indicating an approximate

Updated on: May 13,2024 5

Trial compares therapies for reducing cardiovascular risk among people with rheumatoid arthritis

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainPeople with rheumatoid arthritis are at increased risk of cardiovascular (CV) disease, with studies indicating an approximate

Updated on:May 13,2024 5

The importance of treatment goals in PSA

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainPsA is a type of inflammatory arthritis linked to psoriasis—a chronic condition affecting the skin and nai

Updated on: March 24,2024 12

The importance of treatment goals in PSA

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainPsA is a type of inflammatory arthritis linked to psoriasis—a chronic condition affecting the skin and nai

Updated on:March 24,2024 12

Molecule can quickly, and briefly, boost white blood cell counts

by Yale UniversityCredit: Pixabay/CC0 Public DomainTreatment with a molecule known as A485 can quickly and temporarily increase levels of white blood cells, a critical part of the body's immu

Updated on: March 07,2024 14

Molecule can quickly, and briefly, boost white blood cell counts

by Yale UniversityCredit: Pixabay/CC0 Public DomainTreatment with a molecule known as A485 can quickly and temporarily increase levels of white blood cells, a critical part of the body's immu

Updated on:March 07,2024 14

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on: March 30,2024 0

Possible new biomarker for better detection of numerous inflammatory diseases

by Kiel UniversityTryptophan concentrations in the blood were significantly reduced in 9 of 13 chronic inflammatory diseases examined. Credit: S. Klahn, Exzellenzcluster PMITryptophan is an essen

Updated on:March 30,2024 0

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on: March 07,2024 8

The anterior chamber of the eye as a servant to medical research

by Karolinska InstitutetCredit: B Henrique, PixabayTo mechanistically understand what happens in the living body under physiological and pathological conditions, requires a non-invasive high spat

Updated on:March 07,2024 8

Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on: March 19,2024 18

Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on:March 19,2024 18

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on: January 26,2024 19

Mettl3-dependent m6A modification is essential for effector differentiation and memory formation of CD8+ T cells

byScience China PressDuring viral infection, total m6A levels in Naïve stage, effector stage, and memory stage exhibit dynamic alteration (high-low-high). The presence of Mettl3 promotes CD8 T c

Updated on:January 26,2024 19

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to

Updated on: March 24,2024 15

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to

Updated on:March 24,2024 15

Rheumatoid arthritis patients see big boost in quality of life

by Alan Mozes, Healthday ReporterDutch study found substantial drops in anxiety, depression and disability over 2 decades.(HealthDay)—Rheumatoid arthritis patients can generally look forward to a much

Updated on: March 24,2024 19

Rheumatoid arthritis patients see big boost in quality of life

by Alan Mozes, Healthday ReporterDutch study found substantial drops in anxiety, depression and disability over 2 decades.(HealthDay)—Rheumatoid arthritis patients can generally look forward to a much

Updated on:March 24,2024 19

T cells recognize recent SARS-CoV-2 variants

by NIH/National Institute of Allergy and Infectious DiseasesColorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 (yellow), the virus that causes COVID-19

Updated on: May 08,2024 5

T cells recognize recent SARS-CoV-2 variants

by NIH/National Institute of Allergy and Infectious DiseasesColorized scanning electron micrograph of a dying cell (blue) heavily infected with SARS-CoV-2 (yellow), the virus that causes COVID-19

Updated on:May 08,2024 5

Researchers discover key metabolic process responsible for rapid immune responses

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct i

Updated on: March 19,2024 10

Researchers discover key metabolic process responsible for rapid immune responses

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct i

Updated on:March 19,2024 10