An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on: March 07,2024 19

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on:March 07,2024 19

Trial compares therapies for reducing cardiovascular risk among people with rheumatoid arthritis

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainPeople with rheumatoid arthritis are at increased risk of cardiovascular (CV) disease, with studies indicating an approximate

Updated on: May 13,2024 5

Trial compares therapies for reducing cardiovascular risk among people with rheumatoid arthritis

by Brigham and Women's HospitalCredit: Unsplash/CC0 Public DomainPeople with rheumatoid arthritis are at increased risk of cardiovascular (CV) disease, with studies indicating an approximate

Updated on:May 13,2024 5

The role of T cells in fighting cancer

by CU Anschutz Medical CampusCredit: CC0 Public DomainNew research from CU Cancer Center member Jing Hong Wang, MD, Ph.D., and recent University of Colorado Immunology program graduate Rachel Woo

Updated on: April 24,2024 18

The role of T cells in fighting cancer

by CU Anschutz Medical CampusCredit: CC0 Public DomainNew research from CU Cancer Center member Jing Hong Wang, MD, Ph.D., and recent University of Colorado Immunology program graduate Rachel Woo

Updated on:April 24,2024 18

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on: April 22,2024 15

St18 is a negative regulator of VEGF

by National Institutes of Natural SciencesSt18 inhibits VEGF expression via Sp1 suppression. Credit: Kenta MaruyamaPro-inflammatory cytokines and pathogen-associated molecular patterns such as lipopol

Updated on:April 22,2024 15

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024 5

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024 5

Medication used to control blood sugar in people with type 2 diabetes may also reduce risk of autoimmune diseases

by American College of RheumatologyDipeptidyl peptidase-4 inhibitors commonly used to control blood sugar levels in people with type 2 diabetes may also reduce the risk of autoimmune diseases in these

Updated on: April 07,2024 18

Medication used to control blood sugar in people with type 2 diabetes may also reduce risk of autoimmune diseases

by American College of RheumatologyDipeptidyl peptidase-4 inhibitors commonly used to control blood sugar levels in people with type 2 diabetes may also reduce the risk of autoimmune diseases in these

Updated on:April 07,2024 18

The 'switch' that keeps the immune system from attacking the body

by Ecole Polytechnique Federale de LausanneCredit: CC0 Public DomainA microscopic battle rages in our bodies, as our cells constantly fend off invaders through our immune system: a complex system

Updated on: March 07,2024 20

The 'switch' that keeps the immune system from attacking the body

by Ecole Polytechnique Federale de LausanneCredit: CC0 Public DomainA microscopic battle rages in our bodies, as our cells constantly fend off invaders through our immune system: a complex system

Updated on:March 07,2024 20

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on: January 26,2024 21

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on:January 26,2024 21

Bacteria in the intestine that change in response to inflammation could have an impact on our immune system

by Technion - Israel Institute of TechnologyGraphical abstract . Credit: Cell Host & Microbe (2024). DOI: 10.1016/j.chom.2024.02.003Gut bacteria have emerged as a focal point of scientific explora

Updated on: May 14,2024 0

Bacteria in the intestine that change in response to inflammation could have an impact on our immune system

by Technion - Israel Institute of TechnologyGraphical abstract . Credit: Cell Host & Microbe (2024). DOI: 10.1016/j.chom.2024.02.003Gut bacteria have emerged as a focal point of scientific explora

Updated on:May 14,2024 0

Epigenetics is of critical importance in autoimmune-related skin diseases, says study

by Higher Education PressCredit: Lingyu Gao, Qianjin LuThe central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product p

Updated on: March 27,2024 0

Epigenetics is of critical importance in autoimmune-related skin diseases, says study

by Higher Education PressCredit: Lingyu Gao, Qianjin LuThe central dogma proposed that genetic information predominantly transfers from DNA to RNA during gene expression to make a functional product p

Updated on:March 27,2024 0

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on: May 13,2024 5

Study finds opioids double risk of venous thromboembolism in rheumatoid arthritis patients

by American College of RheumatologyRisk of outcomes (HR, 95% CI) with opioid initiation compared to NSAID initiation after adjustment for propensity score weights and imbalanced covariables (CVD

Updated on:May 13,2024 5

Researchers validate pediatric 'allergic march' in largest national study of its kind

byChildren's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainIn the largest study of its kind, researchers from Children's Hospital of Philadelphia (CHOP) used electronic healt

Updated on: March 05,2024 2

Researchers validate pediatric 'allergic march' in largest national study of its kind

byChildren's Hospital of PhiladelphiaCredit: Unsplash/CC0 Public DomainIn the largest study of its kind, researchers from Children's Hospital of Philadelphia (CHOP) used electronic healt

Updated on:March 05,2024 2