Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on: March 19,2024

Key protein linked to immune disorders

by Hokkaido UniversityThe inflammatory reaction in spinal cords of STAP-1 knockout (KO) mice was less severe than that of wild type (WT) mice (top panels). In parallel, spinal cords of STAP-1 KO

Updated on:March 19,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on: June 18,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on:June 18,2024

Discovery of how to limit asthma attack damage could stop disease

byKing's College LondonCredit: CC0 Public DomainScientists at King's College London have discovered a new cause for asthma that sparks hope for treatment that could prevent the life-thre

Updated on: April 30,2024

Discovery of how to limit asthma attack damage could stop disease

byKing's College LondonCredit: CC0 Public DomainScientists at King's College London have discovered a new cause for asthma that sparks hope for treatment that could prevent the life-thre

Updated on:April 30,2024

New approach to arthritis treatment could avoid serious side-effects

by Queen Mary, University of London(Medical Xpress)—A new approach to arthritis treatment, which avoids unforeseen side-effects by delivering drugs exclusively to affected inflamed joints, has be

Updated on: March 26,2024

New approach to arthritis treatment could avoid serious side-effects

by Queen Mary, University of London(Medical Xpress)—A new approach to arthritis treatment, which avoids unforeseen side-effects by delivering drugs exclusively to affected inflamed joints, has be

Updated on:March 26,2024

A plant-based compound that inhibits reactivation of the HIV viral reservoir, giving the immune system a break

by The Wistar InstituteOverview of HIV inhibitor screening strategy and identification of (–)-hopeaphenol. (A) Representative flow cytometry examples of HIV-GFP reporter expression in unstimulate

Updated on: May 05,2024

A plant-based compound that inhibits reactivation of the HIV viral reservoir, giving the immune system a break

by The Wistar InstituteOverview of HIV inhibitor screening strategy and identification of (–)-hopeaphenol. (A) Representative flow cytometry examples of HIV-GFP reporter expression in unstimulate

Updated on:May 05,2024

Criteria to predict cytokine storm in COVID-19 patients identified

by Temple UniversityCredit: CC0 Public DomainLike a cold front that moves in, setting the stage for severe weather, coronavirus infection triggers showers of infection-fighting immune molecules—s

Updated on: June 06,2024

Criteria to predict cytokine storm in COVID-19 patients identified

by Temple UniversityCredit: CC0 Public DomainLike a cold front that moves in, setting the stage for severe weather, coronavirus infection triggers showers of infection-fighting immune molecules—s

Updated on:June 06,2024

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on: March 25,2024

How an emerging drug class dampens harmful immune reactions

by Angelika Jacobs,University of BaselOverview of complement mechanisms and compstatin-based inhibitor development.aSimplified scheme of the complement cascade with major effector fu

Updated on:March 25,2024

New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on: March 07,2024

New algorithm may greatly speed up the design of 'humanized' antibodies that work

by Weizmann Institute of Science3D structure of an antibody’s “finger,” the portion that binds to a target. The colored regions are responsible for recognizing the target; the gray regions provid

Updated on:March 07,2024

Renal macrophages observed playing crucial role in preventing kidney stones

by Justin Jackson , Medical XpressGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.12.003Researchers at Zhejiang University School of Medicine, China, have investigate

Updated on: March 07,2024

Renal macrophages observed playing crucial role in preventing kidney stones

by Justin Jackson , Medical XpressGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.12.003Researchers at Zhejiang University School of Medicine, China, have investigate

Updated on:March 07,2024

Myogenes identified for spondyloarthritis synovitis

There are disease-specific and inflammation-independent stromal alterations in spondyloarthritis synovitis, according to a study published online Sept. 12 inArthritis & Rheumatism.(HealthDay

Updated on: April 08,2024

Myogenes identified for spondyloarthritis synovitis

There are disease-specific and inflammation-independent stromal alterations in spondyloarthritis synovitis, according to a study published online Sept. 12 inArthritis & Rheumatism.(HealthDay

Updated on:April 08,2024

Factors examined for time to first therapy for biologic DMARD in RA

(HealthDay)—For older patients with rheumatoid arthritis (RA), there is considerable variation in time to receipt of first biologic disease-modifying antirheumatic drug (DMARD) after prescription of t

Updated on: April 07,2024

Factors examined for time to first therapy for biologic DMARD in RA

(HealthDay)—For older patients with rheumatoid arthritis (RA), there is considerable variation in time to receipt of first biologic disease-modifying antirheumatic drug (DMARD) after prescription of t

Updated on:April 07,2024

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on: April 07,2024

Repurposing tocilizumab in scleroderma patients may prevent early lung disease

by Jordyn Imhoff,University of MichiganCredit: CC0 Public DomainResearch led by Michigan Medicine's Scleroderma Program and published in Arthritis & Rheumatology found that tocilizumab,

Updated on:April 07,2024