Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on: March 19,2024

Optimizing boosters: How COVID mRNA vaccines reshape immune memory after each dose

by Tokyo University of ScienceChanges in the clonal populations of CD8+T- cells after successive vaccinations, an ability that can be tuned for developing more effective mRNA vaccines. Cred

Updated on:March 19,2024

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr

Updated on: June 06,2024

Passive smoking linked to increased risk of rheumatoid arthritis

Passive smoking during childhood and/or adulthood is associated with increased risk of rheumatoid arthritis (RA), according to a study recently published inRMD Open.Yann Nguyen, M.D., M.P.H., fr

Updated on:June 06,2024

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024

A near-fatal Valley Fever case opens doors to new treatment method

by Ryan Hatoum,University of California, Los AngelesAbraham Gonzalez-Martinez, who had a dangerous case of Valley Fever, at UCLA Mattel Children’s Hospital. Credit: University of California, Los

Updated on: May 08,2024

A near-fatal Valley Fever case opens doors to new treatment method

by Ryan Hatoum,University of California, Los AngelesAbraham Gonzalez-Martinez, who had a dangerous case of Valley Fever, at UCLA Mattel Children’s Hospital. Credit: University of California, Los

Updated on:May 08,2024

Moms with lupus more likely to have children with autism, study suggests

by Serena Gordon, Healthday ReporterBut overall risk is low, shouldn't influence parenting decisions, expert says.(HealthDay)—Women with lupus are twice as likely to have a child with autism compa

Updated on: March 24,2024

Moms with lupus more likely to have children with autism, study suggests

by Serena Gordon, Healthday ReporterBut overall risk is low, shouldn't influence parenting decisions, expert says.(HealthDay)—Women with lupus are twice as likely to have a child with autism compa

Updated on:March 24,2024

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on: March 19,2024

Study uncovers novel mechanisms behind food allergies

by Melissa Rohman,Northwestern UniversityCredit:Mucosal Immunology(2023). DOI: 10.1016/j.mucimm.2023.12.001A recent Northwestern Medicine study has shed light on the mechanisms of a

Updated on:March 19,2024

Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on: March 24,2024

Researchers uncover new mode of action for HUMIRA in rheumatoid arthritis patients

by Rockefeller University PressIn the presence of adalimumab, TNF on the surface of a monocyte interacts with receptor molecules on the surface of two regulatory T cells, thereby promoting their

Updated on:March 24,2024

Researchers describe how birch pollen affects immune cells

by Jan Grabowski, Zentrum für Experimentelle und Klinische InfektionsforschungAPE exposure induces transcriptional changes in moDC. (A) IL-12p70 content in supernatants of moDC stimulated with 100 ng/

Updated on: March 05,2024

Researchers describe how birch pollen affects immune cells

by Jan Grabowski, Zentrum für Experimentelle und Klinische InfektionsforschungAPE exposure induces transcriptional changes in moDC. (A) IL-12p70 content in supernatants of moDC stimulated with 100 ng/

Updated on:March 05,2024

Immune cells monitor blood platelet maturation in bone marrow, researchers discover

byLudwig Maximilian University of MunichTissue homeostasis: plasmacytoid dendritic cells monitor bone marrow, initiating on-demand megakaryocyte formation. Uniform distribution of megakaryocytes

Updated on: July 30,2024

Immune cells monitor blood platelet maturation in bone marrow, researchers discover

byLudwig Maximilian University of MunichTissue homeostasis: plasmacytoid dendritic cells monitor bone marrow, initiating on-demand megakaryocyte formation. Uniform distribution of megakaryocytes

Updated on:July 30,2024

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on: May 07,2024

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on:May 07,2024

10 percent of US adults physically limited by arthritis, CDC reports

by Steven Reinberg, Healthday ReporterExperts say obesity epidemic has widened the pool of disabled.(HealthDay)—More than 50 million Americans have arthritis, and almost half of them can't perform

Updated on: March 24,2024

10 percent of US adults physically limited by arthritis, CDC reports

by Steven Reinberg, Healthday ReporterExperts say obesity epidemic has widened the pool of disabled.(HealthDay)—More than 50 million Americans have arthritis, and almost half of them can't perform

Updated on:March 24,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on: June 18,2024

Team explores role of 'stimulator of interferon genes' in body's innate immune system

by Tokai National Higher Education and Research SystemA graphical illustration of cholesterol- and palmitoylation-dependent STING clustering at the TGN. Credit: Institute for Glyco-core ResearchWhen p

Updated on:June 18,2024