Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on: January 26,2024 21

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Updated on:January 26,2024 21

COVID-19 can trigger auto-immune disorders-related antibodies, causing thrombosis and other complications

by Maria Fernanda Ziegler,FAPESPThe systems immunology approach identifies an aging effect on autoantibody levels of COVID-19 patients. Credit:npj Aging(2023). DOI: 10.1038/s41514-02

Updated on: April 10,2024 18

COVID-19 can trigger auto-immune disorders-related antibodies, causing thrombosis and other complications

by Maria Fernanda Ziegler,FAPESPThe systems immunology approach identifies an aging effect on autoantibody levels of COVID-19 patients. Credit:npj Aging(2023). DOI: 10.1038/s41514-02

Updated on:April 10,2024 18

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on: June 06,2024 5

Oral deucravacitinib benefits patients with lupus

by WileyCredit: CC0 Public DomainTyrosine kinases are enzymes that play central roles in signaling by cytokines involved in the pathogenesis of autoimmune diseases, including lupus. A recent phas

Updated on:June 06,2024 5

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on: April 22,2024 13

STIM-mediated calcium influx regulates maintenance and selection of germinal center B cells: Study

by Osaka UniversityCredit:Journal of Experimental Medicine(2023). DOI: 10.1084/jem.20222178Germinal centers (GCs) are specialized microenvironments where antigen (Ag)-specific B cells

Updated on:April 22,2024 13

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on: March 25,2024 15

How one inflammatory disorder exacerbates another

by Katherine Unger Baillie,University of PennsylvaniaInflammation in the gums can increase susceptibility to other forms of inflammation, such as arthritis, through changes to immune cell precur

Updated on:March 25,2024 15

10 percent of US adults physically limited by arthritis, CDC reports

by Steven Reinberg, Healthday ReporterExperts say obesity epidemic has widened the pool of disabled.(HealthDay)—More than 50 million Americans have arthritis, and almost half of them can't perform

Updated on: March 24,2024 16

10 percent of US adults physically limited by arthritis, CDC reports

by Steven Reinberg, Healthday ReporterExperts say obesity epidemic has widened the pool of disabled.(HealthDay)—More than 50 million Americans have arthritis, and almost half of them can't perform

Updated on:March 24,2024 16

Treatment options for patients whose blood cancer relapses after CAR-T cell therapy

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainMount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the bloo

Updated on: April 09,2024 18

Treatment options for patients whose blood cancer relapses after CAR-T cell therapy

by The Mount Sinai HospitalCredit: Pixabay/CC0 Public DomainMount Sinai and Memorial Sloan Kettering Cancer Center (MSK) researchers have identified therapies that can help patients with the bloo

Updated on:April 09,2024 18

Weather and arthritis: Is there really a connection?

It 's long been conventional wisdom that weather makes arthritis pain worse.The issue has been studied through the years, with conflicting findings. But three recent studies foundweather&nbsp

Updated on: May 29,2024 4

Weather and arthritis: Is there really a connection?

It 's long been conventional wisdom that weather makes arthritis pain worse.The issue has been studied through the years, with conflicting findings. But three recent studies foundweather&nbsp

Updated on:May 29,2024 4

First-degree relatives have high perceived risk for rheumatoid arthritis

by Elana GotkineFirst-degree relatives (FDRs) of patients with rheumatoid arthritis (RA) have a high perceived risk for developing RA, according to a study published online Dec. 5 inRMD Open.Sar

Updated on: June 26,2024 8

First-degree relatives have high perceived risk for rheumatoid arthritis

by Elana GotkineFirst-degree relatives (FDRs) of patients with rheumatoid arthritis (RA) have a high perceived risk for developing RA, according to a study published online Dec. 5 inRMD Open.Sar

Updated on:June 26,2024 8

Sex-specific immune response in COVID-19 linked to cellular metabolism

by Rick Harrison,Yale UniversityImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers studying COVID-19 patients have found a metabo

Updated on: April 13,2024 12

Sex-specific immune response in COVID-19 linked to cellular metabolism

by Rick Harrison,Yale UniversityImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers studying COVID-19 patients have found a metabo

Updated on:April 13,2024 12

Rheumatoid arthritis patients see big boost in quality of life

by Alan Mozes, Healthday ReporterDutch study found substantial drops in anxiety, depression and disability over 2 decades.(HealthDay)—Rheumatoid arthritis patients can generally look forward to a much

Updated on: March 24,2024 19

Rheumatoid arthritis patients see big boost in quality of life

by Alan Mozes, Healthday ReporterDutch study found substantial drops in anxiety, depression and disability over 2 decades.(HealthDay)—Rheumatoid arthritis patients can generally look forward to a much

Updated on:March 24,2024 19

Preclinical study of COVID-19 vaccine candidate shows potent T-cell responses

by University of Alabama at BirminghamCredit: University of Alabama at BirminghamPreclinical studies of a COVID-19 vaccine candidate at the University of Alabama at Birmingham show positive resul

Updated on: April 10,2024 10

Preclinical study of COVID-19 vaccine candidate shows potent T-cell responses

by University of Alabama at BirminghamCredit: University of Alabama at BirminghamPreclinical studies of a COVID-19 vaccine candidate at the University of Alabama at Birmingham show positive resul

Updated on:April 10,2024 10