Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on: September 18,2024

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Updated on:September 18,2024

Myogenes identified for spondyloarthritis synovitis

There are disease-specific and inflammation-independent stromal alterations in spondyloarthritis synovitis, according to a study published online Sept. 12 inArthritis & Rheumatism.(HealthDay

Updated on: April 08,2024

Myogenes identified for spondyloarthritis synovitis

There are disease-specific and inflammation-independent stromal alterations in spondyloarthritis synovitis, according to a study published online Sept. 12 inArthritis & Rheumatism.(HealthDay

Updated on:April 08,2024

How do MAIT cells identify and attack foreign invaders?

byUniversity of MelbourneCredit: CC0 Public DomainMelbourne researchers have identified what makes a specialised immune cell, known as mucosal-associated invariant T (MAIT), cells boost their nu

Updated on: April 20,2024

How do MAIT cells identify and attack foreign invaders?

byUniversity of MelbourneCredit: CC0 Public DomainMelbourne researchers have identified what makes a specialised immune cell, known as mucosal-associated invariant T (MAIT), cells boost their nu

Updated on:April 20,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024

Interdisciplinary guidelines to optimize the treatment of childhood arthritis

by Aarhus UniversityCredit: Unsplash/CC0 Public DomainPreviously, there were no uniform guidelines for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile ar

Updated on: April 07,2024

Interdisciplinary guidelines to optimize the treatment of childhood arthritis

by Aarhus UniversityCredit: Unsplash/CC0 Public DomainPreviously, there were no uniform guidelines for the treatment of arthritis of the jaw, a potentially debilitating consequence of juvenile ar

Updated on:April 07,2024

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on: May 07,2024

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

Updated on:May 07,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on: May 05,2024

The secret lives of T cell receptors and their role in the immune response

by Delthia Ricks , Medical XpressCredit: CC0 Public DomainCanadian immunologists have identified a mechanism that promotes the activation of T cell receptors by altering how one of its components inte

Updated on:May 05,2024

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on: March 07,2024

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Updated on:March 07,2024

Omega-3 fatty acids linked with slower progression of ALS

by Harvard T.H. Chan School of Public HealthCredit: Lawrencekhoo / Wikipedia.Consuming omega-3 fatty acids—particularly alpha-linolenic acid (ALA), a nutrient found in foods including flaxseeds,

Updated on: June 26,2024

Omega-3 fatty acids linked with slower progression of ALS

by Harvard T.H. Chan School of Public HealthCredit: Lawrencekhoo / Wikipedia.Consuming omega-3 fatty acids—particularly alpha-linolenic acid (ALA), a nutrient found in foods including flaxseeds,

Updated on:June 26,2024

COVID-19 mutations and their links to excessive immune responses

by King Abdullah University of Science and TechnologySchematic representation summarizing the main findings. The KR mutant SARS-CoV-2 infected patients display high magnitude of immune response.

Updated on: April 13,2024

COVID-19 mutations and their links to excessive immune responses

by King Abdullah University of Science and TechnologySchematic representation summarizing the main findings. The KR mutant SARS-CoV-2 infected patients display high magnitude of immune response.

Updated on:April 13,2024

Scientists create device to deliver immunotherapy without side effects

by Houston MethodistSmaller than a grain of rice, this tiny nanodevice, invented by a Houston Methodist scientist, delivers immunotherapy straight into a tumor, eliminating both side effects and

Updated on: April 22,2024

Scientists create device to deliver immunotherapy without side effects

by Houston MethodistSmaller than a grain of rice, this tiny nanodevice, invented by a Houston Methodist scientist, delivers immunotherapy straight into a tumor, eliminating both side effects and

Updated on:April 22,2024

A possible mechanism of lymphocyte deficiency in patients with COVID-19

by Russian Foundation for Basic ResearchCreative rendition of SARS-CoV-2 particles (not to scale). Credit: National Institute of Allergy and Infectious Diseases, NIHScientists from RUDN, National Medi

Updated on: April 10,2024

A possible mechanism of lymphocyte deficiency in patients with COVID-19

by Russian Foundation for Basic ResearchCreative rendition of SARS-CoV-2 particles (not to scale). Credit: National Institute of Allergy and Infectious Diseases, NIHScientists from RUDN, National Medi

Updated on:April 10,2024