Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on: April 08,2024 11

Combined inhibition of TNF-alpha, IL-17 effective in RA model

(HealthDay)—Combined inhibition of tumor necrosis factor (TNF) α and interleukin (IL)-17 is more effective than single blockade in cultures of human fibroblast-like synoviocytes (FLS), according to an

Updated on:April 08,2024 11

Hope for patients with rare Sjögren's syndrome

by Newcastle UniversityProfessor Fai Ng. Credit: Newcastle UniversityA new study has shed light on a debilitating autoimmune condition by identifying a number of subtypes of the disease which cou

Updated on: March 24,2024 10

Hope for patients with rare Sjögren's syndrome

by Newcastle UniversityProfessor Fai Ng. Credit: Newcastle UniversityA new study has shed light on a debilitating autoimmune condition by identifying a number of subtypes of the disease which cou

Updated on:March 24,2024 10

Multifactorial mechanisms underlie leg weakness in hip OA

Multiple factors contribute to leg weakness in people with hip osteoarthritis, with muscle atrophy being the strongest contributor, according to the results of a systematic review published online Jul

Updated on: April 08,2024 15

Multifactorial mechanisms underlie leg weakness in hip OA

Multiple factors contribute to leg weakness in people with hip osteoarthritis, with muscle atrophy being the strongest contributor, according to the results of a systematic review published online Jul

Updated on:April 08,2024 15

Developing new classification criteria for improving antiphospholipid syndrome research

by Hospital for Special SurgeryCredit: CC0 Public DomainAn international team of more than 80 collaborators led by Hospital for Special Surgery (HSS) investigators is developing new classificatio

Updated on: March 26,2024 13

Developing new classification criteria for improving antiphospholipid syndrome research

by Hospital for Special SurgeryCredit: CC0 Public DomainAn international team of more than 80 collaborators led by Hospital for Special Surgery (HSS) investigators is developing new classificatio

Updated on:March 26,2024 13

Study advances understanding of liver immune response in cirrhosis

byMiguel Hernandez University of ElcheLSECtin expression in the liver inversely correlates with Th17 expansion in cirrhosis. (A) Representative Immunohistochemistry of the lymphocyte-specific tr

Updated on: April 28,2024 0

Study advances understanding of liver immune response in cirrhosis

byMiguel Hernandez University of ElcheLSECtin expression in the liver inversely correlates with Th17 expansion in cirrhosis. (A) Representative Immunohistochemistry of the lymphocyte-specific tr

Updated on:April 28,2024 0

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on: May 19,2024 3

Researchers unlock predictive biomarkers for common hip disorder

by University of MissouriBoxplots of significantly different median urine biomarker concentrations between the DDH cohort and healthy controls (P < 0.05). Median and the interquartile range ar

Updated on:May 19,2024 3

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on: April 20,2024 14

Clinical trial denounces use of platelet-rich plasma injections for knee joint osteoarthritis

by University of MelbournePlatelet-rich plasma injections have become a popular form of treatment for painful joints in recent years but researchers have established they are no better than place

Updated on:April 20,2024 14

Knee arthritis: Steroid shots may not help long-term, ozone injections promising

Two studies test out old and new treatments for the debilitating ailment.(HealthDay)—Millions of aging Americans are plagued by arthritic knees, and two new studies offer insight into what might—or mi

Updated on: April 08,2024 15

Knee arthritis: Steroid shots may not help long-term, ozone injections promising

Two studies test out old and new treatments for the debilitating ailment.(HealthDay)—Millions of aging Americans are plagued by arthritic knees, and two new studies offer insight into what might—or mi

Updated on:April 08,2024 15

Researchers uncover key to preventing fibrosis in biomaterial implants

byUniversity of VirginiaHydrogel fabrication and subcutaneous implantation. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adf2675A study from the University of Virginia's De

Updated on: November 01,2024 0

Researchers uncover key to preventing fibrosis in biomaterial implants

byUniversity of VirginiaHydrogel fabrication and subcutaneous implantation. Credit:Science Advances(2024). DOI: 10.1126/sciadv.adf2675A study from the University of Virginia's De

Updated on:November 01,2024 0

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on: April 24,2024 20

TET proteins regulate factors essential for normal antibody production

by La Jolla Institute for ImmunologyMutant B cells lacking TET2 and TET3 produce an overabundance of a class of antibody called IgM, whereas normal control B cells churned out more effective antibodie

Updated on:April 24,2024 20

CARv3-TEAM-E T-cell treatment beneficial for recurrent glioblastoma

by Elana GotkineFor patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-spec

Updated on: March 27,2024 0

CARv3-TEAM-E T-cell treatment beneficial for recurrent glioblastoma

by Elana GotkineFor patients with recurrent glioblastoma, treatment with chimeric antigen receptor (CAR) T-cells engineered to target the epidermal growth factor receptor (EGFR) variant III tumor-spec

Updated on:March 27,2024 0

Race plays a role in children's food allergies

by Nancy Difiore,Rush University Medical CenterCredit: Pixabay/CC0 Public DomainBlack children have significantly higher rates of shellfish and fish allergies than white children, confirming tha

Updated on: March 05,2024 15

Race plays a role in children's food allergies

by Nancy Difiore,Rush University Medical CenterCredit: Pixabay/CC0 Public DomainBlack children have significantly higher rates of shellfish and fish allergies than white children, confirming tha

Updated on:March 05,2024 15