An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on: March 30,2024

An infamous 'inflammasome'—a rogue protein complex—appears to underlie a rare and disabling autoimmune disorder

by Delthia Ricks , Medical XpressCa2+ influx is required for PIEZO-dependent NLRP3 inflammasome activation. Credit:Science Immunology(2023). DOI: 10.1126/sciimmunol.adf4699Autoimmune disea

Updated on:March 30,2024

Hope for patients with rare Sjögren's syndrome

by Newcastle UniversityProfessor Fai Ng. Credit: Newcastle UniversityA new study has shed light on a debilitating autoimmune condition by identifying a number of subtypes of the disease which cou

Updated on: March 24,2024

Hope for patients with rare Sjögren's syndrome

by Newcastle UniversityProfessor Fai Ng. Credit: Newcastle UniversityA new study has shed light on a debilitating autoimmune condition by identifying a number of subtypes of the disease which cou

Updated on:March 24,2024

Smoking cessation may reduce risk of rheumatoid arthritis

by Brigham and Women's HospitalCredit: CC0 Public DomainSmoking is an important risk factor for developing the most common form of rheumatoid arthritis (RA) and other inflammatory diseases, b

Updated on: May 13,2024

Smoking cessation may reduce risk of rheumatoid arthritis

by Brigham and Women's HospitalCredit: CC0 Public DomainSmoking is an important risk factor for developing the most common form of rheumatoid arthritis (RA) and other inflammatory diseases, b

Updated on:May 13,2024

Smokers who consume too much sodium at greater risk of developing rheumatoid arthritis

by Oxford University PressCredit: Vera Kratochvil/public domainA new study published online in the journalRheumatologytoday indicates that the interaction between high sodium intake a

Updated on: May 13,2024

Smokers who consume too much sodium at greater risk of developing rheumatoid arthritis

by Oxford University PressCredit: Vera Kratochvil/public domainA new study published online in the journalRheumatologytoday indicates that the interaction between high sodium intake a

Updated on:May 13,2024

Immune cells monitor blood platelet maturation in bone marrow, researchers discover

byLudwig Maximilian University of MunichTissue homeostasis: plasmacytoid dendritic cells monitor bone marrow, initiating on-demand megakaryocyte formation. Uniform distribution of megakaryocytes

Updated on: July 30,2024

Immune cells monitor blood platelet maturation in bone marrow, researchers discover

byLudwig Maximilian University of MunichTissue homeostasis: plasmacytoid dendritic cells monitor bone marrow, initiating on-demand megakaryocyte formation. Uniform distribution of megakaryocytes

Updated on:July 30,2024

Genetic key to lupus shows potential of personalised medicine

by Australian National UniversityDr Julia Ellyard(Medical Xpress)—Medical researchers have used DNA sequencing to identify a gene variant responsible for causing lupus in a young patient.The deve

Updated on: June 15,2024

Genetic key to lupus shows potential of personalised medicine

by Australian National UniversityDr Julia Ellyard(Medical Xpress)—Medical researchers have used DNA sequencing to identify a gene variant responsible for causing lupus in a young patient.The deve

Updated on:June 15,2024

Knee sound based detector for osteoarthritis prediction

by University of MalayaMicrophone attached to subject’s kneeUniversity Malaya researchers have developed a non-invasive, radiation-free, early stage detection system called the Knee Sound Detector to

Updated on: May 29,2024

Knee sound based detector for osteoarthritis prediction

by University of MalayaMicrophone attached to subject’s kneeUniversity Malaya researchers have developed a non-invasive, radiation-free, early stage detection system called the Knee Sound Detector to

Updated on:May 29,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on: April 20,2024

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

Updated on:April 20,2024

Prototype equipment can detect rheumatoid arthritis

by University of TwenteCredit: University of TwenteAccording to a first clinical study published in the scientific journal Photoacoustics, the University of Twente and various European partners h

Updated on: March 30,2024

Prototype equipment can detect rheumatoid arthritis

by University of TwenteCredit: University of TwenteAccording to a first clinical study published in the scientific journal Photoacoustics, the University of Twente and various European partners h

Updated on:March 30,2024

Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa

Updated on: April 08,2024

Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa

Updated on:April 08,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on: March 25,2024

Immune system's moonlighters point the way to a new therapeutic target

FEBRUARY 20, 2024byCold Spring Harbor LaboratoryGraphical abstract. Credit:Molecular Cell(2024). DOI: 10.1016/j.molcel.2024.01.007Our immune system is remarkably powerful. It quickly

Updated on:March 25,2024

A common skin bacterium put children with severe eczema at higher risk of food allergy

by King's College LondonCredit: CC0 Public DomainIn a new study published today in theJournal of Allergy and Clinical Immunology, scientists from King's College London have found th

Updated on: May 08,2024

A common skin bacterium put children with severe eczema at higher risk of food allergy

by King's College LondonCredit: CC0 Public DomainIn a new study published today in theJournal of Allergy and Clinical Immunology, scientists from King's College London have found th

Updated on:May 08,2024