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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
Latest Articles
Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav

Researchers reveal molecular mechanism of cytokine storm induced by coronavirus

by Zhang Nannan,Chinese Academy of SciencesSARS-CoV-2 stabilizes host mRNAs to induce cytokine storm. Credit: Xue Yuanchao's groupIn the past four years, the pathogen responsible for Coronav
Scientists create device to deliver immunotherapy without side effects

Scientists create device to deliver immunotherapy without side effects

by Houston MethodistSmaller than a grain of rice, this tiny nanodevice, invented by a Houston Methodist scientist, delivers immunotherapy straight into a tumor, eliminating both side effects and

Scientists create device to deliver immunotherapy without side effects

by Houston MethodistSmaller than a grain of rice, this tiny nanodevice, invented by a Houston Methodist scientist, delivers immunotherapy straight into a tumor, eliminating both side effects and
Omega-3 fatty acids linked with slower progression of ALS

Omega-3 fatty acids linked with slower progression of ALS

by Harvard T.H. Chan School of Public HealthCredit: Lawrencekhoo / Wikipedia.Consuming omega-3 fatty acids—particularly alpha-linolenic acid (ALA), a nutrient found in foods including flaxseeds,

Omega-3 fatty acids linked with slower progression of ALS

by Harvard T.H. Chan School of Public HealthCredit: Lawrencekhoo / Wikipedia.Consuming omega-3 fatty acids—particularly alpha-linolenic acid (ALA), a nutrient found in foods including flaxseeds,
Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa

Leflunomide considered safe, effective for psoriatic arthritis

Leflunomide is effective for the treatment of patients with psoriatic arthritis in daily clinical practice, according to a study published online Oct. 6 inArthritis Care & Research.(HealthDa
The PANoptosome: A new frontier in innate immune responses

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun

The PANoptosome: A new frontier in innate immune responses

by St. Jude Children's Research HospitalCredit: CC0 Public DomainSt. Jude Children's Research Hospital immunologists have identified how immune sensors in infected cells organize and laun
Review discusses metabolic reprogramming of T cells

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr

Review discusses metabolic reprogramming of T cells

by Cactus CommunicationsT cell immunotherapy can be optimized by understanding the metabolism of T cells. This review article summarizes the intricacies of effector and memory T cell metabolic reprogr
Using molecular scissors to improve CAR-T cell therapy

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D

Using molecular scissors to improve CAR-T cell therapy

by Susan Buckles,Mayo ClinicAn in vitro model for chronic stimulation induces phenotypic and functional signs of exhaustion in CART19-28ζ cells. Credit:Nature Communications(2024). D
COVID-19 mutations and their links to excessive immune responses

COVID-19 mutations and their links to excessive immune responses

by King Abdullah University of Science and TechnologySchematic representation summarizing the main findings. The KR mutant SARS-CoV-2 infected patients display high magnitude of immune response.

COVID-19 mutations and their links to excessive immune responses

by King Abdullah University of Science and TechnologySchematic representation summarizing the main findings. The KR mutant SARS-CoV-2 infected patients display high magnitude of immune response.
Researchers develop statistical method for genetic mapping of autoimmune diseases

Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio

Researchers develop statistical method for genetic mapping of autoimmune diseases

byBrigham and Women’s HospitalSchematic overview of SCENT and SCENT enhancer–gene pairs across nine single-cell multimodal datasets.a, SCENT identifies (1) activecis-regulatory regio
A small T cell switch with a big impact

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&

A small T cell switch with a big impact

by Julius-Maximilians-Universität WürzburgCredit: CC0 Public DomainT cells play a key role in the human immune system. They are capable of distinguishing diseased or foreign tissue from the body&
Smoking cessation may reduce risk of rheumatoid arthritis

Smoking cessation may reduce risk of rheumatoid arthritis

by Brigham and Women's HospitalCredit: CC0 Public DomainSmoking is an important risk factor for developing the most common form of rheumatoid arthritis (RA) and other inflammatory diseases, b

Smoking cessation may reduce risk of rheumatoid arthritis

by Brigham and Women's HospitalCredit: CC0 Public DomainSmoking is an important risk factor for developing the most common form of rheumatoid arthritis (RA) and other inflammatory diseases, b
Study sheds light on pregnancy complications and overturns common belief

Study sheds light on pregnancy complications and overturns common belief

by Hospital for Special Surgery"Many doctors may be unnecessarily treating some pregnant women who have antiphospholipid antibodies (aPLs) with anticoagulants, such as expensive heparin inje

Study sheds light on pregnancy complications and overturns common belief

by Hospital for Special Surgery"Many doctors may be unnecessarily treating some pregnant women who have antiphospholipid antibodies (aPLs) with anticoagulants, such as expensive heparin inje