CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on: April 09,2024

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

Updated on:April 09,2024

Fecal microbiota transplantation for active peripheral psoriatic arthritis shows no advantage

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainIn this proof-of-concept study, Maja Skov Kragsnaes and colleagues evaluated efficacy and safety of FMT in people with pso

Updated on: June 17,2024

Fecal microbiota transplantation for active peripheral psoriatic arthritis shows no advantage

by European Alliance of Associations for RheumatologyCredit: CC0 Public DomainIn this proof-of-concept study, Maja Skov Kragsnaes and colleagues evaluated efficacy and safety of FMT in people with pso

Updated on:June 17,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on: May 05,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on:May 05,2024

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on: September 04,2024

Synthetic immunology: Approaching a turning point in the treatment and prevention of disease

byHeidelberg UniversityTop-down versus bottom-up synthetic immunology. Credit:Nature Nanotechnology(2024). DOI: 10.1038/s41565-024-01744-9Synthetic immunology, an innovative field of

Updated on:September 04,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

Nasopharyngeal carcinoma treatment using exosomes derived from γδ-T cells synergized with radiotherapy

by The University of Hong KongExos induce apoptosis of NPC tumor cells through death receptor ligation. NPC43 or C666-1 cells were treated with PBS, ultracentrifuged pellets isolated from FBS–exo

Updated on: May 07,2024

Nasopharyngeal carcinoma treatment using exosomes derived from γδ-T cells synergized with radiotherapy

by The University of Hong KongExos induce apoptosis of NPC tumor cells through death receptor ligation. NPC43 or C666-1 cells were treated with PBS, ultracentrifuged pellets isolated from FBS–exo

Updated on:May 07,2024

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on: June 01,2024

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on:June 01,2024

RA linked to restrictive, obstructive spirometry patterns

(HealthDay)—Rheumatoid arthritis (RA) is associated with restrictive and obstructive spirometry patterns, with the strongest associations seen for severe patterns, according to a study published onlin

Updated on: June 01,2024

RA linked to restrictive, obstructive spirometry patterns

(HealthDay)—Rheumatoid arthritis (RA) is associated with restrictive and obstructive spirometry patterns, with the strongest associations seen for severe patterns, according to a study published onlin

Updated on:June 01,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on: April 08,2024

Autoimmune diseases in ALS patients linked to genetic mutation

by Sarah Lichtman,Cedars-Sinai Medical CenterRobert Baloh, MD, PhD, at work in his laboratory. Credit: Cedars-SinaiA study published today in the journalNaturecould help explain why

Updated on:April 08,2024

Moderna and Pfizer-BioNTech vaccines prime T cells to fight SARS-CoV-2 variants

by La Jolla Institute for ImmunologyT cells from people who have recovered from COVID-19 or received the Moderna or Pfizer-BioNTech vaccines are still able to recognize several concerning SARS-Co

Updated on: April 20,2024

Moderna and Pfizer-BioNTech vaccines prime T cells to fight SARS-CoV-2 variants

by La Jolla Institute for ImmunologyT cells from people who have recovered from COVID-19 or received the Moderna or Pfizer-BioNTech vaccines are still able to recognize several concerning SARS-Co

Updated on:April 20,2024

Platelet-rich plasma treatment shows efficacy for osteoarthritis

by Homa Shalchi,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainA pilot study conducted by researchers at Baylor College of Medicine combined wearable technology and patient-reported

Updated on: May 26,2024

Platelet-rich plasma treatment shows efficacy for osteoarthritis

by Homa Shalchi,Baylor College of MedicineCredit: Pixabay/CC0 Public DomainA pilot study conducted by researchers at Baylor College of Medicine combined wearable technology and patient-reported

Updated on:May 26,2024

Exercise training improves cardiac parameters in lupus

(HealthDay) -- For inactive patients with systemic lupus erythematosus (SLE), a three-month exercise training program is associated with improved chronotropic reserve and heart rate recovery, accordin

Updated on: March 24,2024

Exercise training improves cardiac parameters in lupus

(HealthDay) -- For inactive patients with systemic lupus erythematosus (SLE), a three-month exercise training program is associated with improved chronotropic reserve and heart rate recovery, accordin

Updated on:March 24,2024