Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on: May 30,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on:May 30,2024

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on: June 01,2024

Is metabolic syndrome a modifiable risk factor for gout?

by WileyCredit: Pixabay/CC0 Public DomainIn a study published inArthritis & Rheumatologythat included nearly 1.3 million men aged 20–39 years who participated in three serial heal

Updated on:June 01,2024

Scientists find genetic link between sugary drinks and gout

by University of Otago(Medical Xpress)—University of Otago and Auckland scientists have for the first time discovered a human gene variant that can "turn bad" when affected by sugary dr

Updated on: March 24,2024

Scientists find genetic link between sugary drinks and gout

by University of Otago(Medical Xpress)—University of Otago and Auckland scientists have for the first time discovered a human gene variant that can "turn bad" when affected by sugary dr

Updated on:March 24,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

Points to consider when using interferon assays

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainInterferons are type of protein called a cytokine. They have important roles in the immune system. Interfe

Updated on: May 26,2024

Points to consider when using interferon assays

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainInterferons are type of protein called a cytokine. They have important roles in the immune system. Interfe

Updated on:May 26,2024

Unique immune response found in patients who experience inflammatory arthritis as side effect of cancer therapies

by Brigham and Women's HospitalMultiplexed immunofluorescence of synovial tissue. Multiplexed immunofluorescence images showing an example of a Ki67+PD-1+synovial CD8 T cell (white arro

Updated on: July 03,2024

Unique immune response found in patients who experience inflammatory arthritis as side effect of cancer therapies

by Brigham and Women's HospitalMultiplexed immunofluorescence of synovial tissue. Multiplexed immunofluorescence images showing an example of a Ki67+PD-1+synovial CD8 T cell (white arro

Updated on:July 03,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on: May 05,2024

X chromosome gene may explain why women are more prone to autoimmune diseases

by Alice Walton,University of California, Los Angeles(A) Using the high-throughput sequencing approach, sexually biased X chromosome genes in CD4+T cells were determined for C57BL/6J naive

Updated on:May 05,2024

Key discovery in psoriatic arthritis points way for developing targeted treatments

by University of OxfordCredit: Unsplash/CC0 Public DomainA new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University o

Updated on: June 15,2024

Key discovery in psoriatic arthritis points way for developing targeted treatments

by University of OxfordCredit: Unsplash/CC0 Public DomainA new study has revealed psoriatic arthritis may be activated by the same trigger in different patients. Researchers from the University o

Updated on:June 15,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on: April 13,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on:April 13,2024

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on: April 20,2024

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on:April 20,2024

Exercise training improves cardiac parameters in lupus

(HealthDay) -- For inactive patients with systemic lupus erythematosus (SLE), a three-month exercise training program is associated with improved chronotropic reserve and heart rate recovery, accordin

Updated on: March 24,2024

Exercise training improves cardiac parameters in lupus

(HealthDay) -- For inactive patients with systemic lupus erythematosus (SLE), a three-month exercise training program is associated with improved chronotropic reserve and heart rate recovery, accordin

Updated on:March 24,2024

Is it brain infection or cancer? A new rapid test could hold the answer

by Thomas Jefferson UniversityGram stain of meningococci from a culture showing Gram negative (pink) bacteria, often in pairs. Credit: public domainWhen patients present with neurologic symptoms

Updated on: April 16,2024

Is it brain infection or cancer? A new rapid test could hold the answer

by Thomas Jefferson UniversityGram stain of meningococci from a culture showing Gram negative (pink) bacteria, often in pairs. Credit: public domainWhen patients present with neurologic symptoms

Updated on:April 16,2024