New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on: April 08,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on:April 08,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on: April 15,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on:April 15,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on: April 16,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on:April 16,2024

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to

Updated on: March 24,2024

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to

Updated on:March 24,2024

Fatigue common even with early rheumatoid arthritis

(HealthDay)—Fatigue is prevalent and persistent in early rheumatoid arthritis (RA), according to a study published online Dec. 27 inRheumatology.Onosi Sylvia Ifesemen, M.B.B.S., from the Univers

Updated on: June 17,2024

Fatigue common even with early rheumatoid arthritis

(HealthDay)—Fatigue is prevalent and persistent in early rheumatoid arthritis (RA), according to a study published online Dec. 27 inRheumatology.Onosi Sylvia Ifesemen, M.B.B.S., from the Univers

Updated on:June 17,2024

Drug shows promise against arthritis common in people with psoriasis

by Steven Reinberg, Healthday ReporterNew medication improved skin condition, lessened swelling, study finds.(HealthDay)—A new drug called brodalumab appears to be effective in treating patients suffe

Updated on: March 24,2024

Drug shows promise against arthritis common in people with psoriasis

by Steven Reinberg, Healthday ReporterNew medication improved skin condition, lessened swelling, study finds.(HealthDay)—A new drug called brodalumab appears to be effective in treating patients suffe

Updated on:March 24,2024

The importance of treatment goals in PSA

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainPsA is a type of inflammatory arthritis linked to psoriasis—a chronic condition affecting the skin and nai

Updated on: March 24,2024

The importance of treatment goals in PSA

by European Alliance of Associations for Rheumatology (EULAR)Credit: Pixabay/CC0 Public DomainPsA is a type of inflammatory arthritis linked to psoriasis—a chronic condition affecting the skin and nai

Updated on:March 24,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on: June 15,2024

Boosting CAR-T cell therapies from under the skin

by Benjamin Boettner,Harvard UniversityT-cell enhancing scaffolds can be locally injected under the skin following CAR-T cell therapy, and allowcirculating CAR-T cells to infiltrate their 3-dime

Updated on:June 15,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on: May 07,2024

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Updated on:May 07,2024

Swimming short fibrous nasal drops achieve intraventricular administration

byScience China PressInspired by swimming fish and the microstructure of the nasal cavity, short-swimming fibrous nasal drops with the ability to transport drugs along the nasal mucosa were inno

Updated on: April 28,2024

Swimming short fibrous nasal drops achieve intraventricular administration

byScience China PressInspired by swimming fish and the microstructure of the nasal cavity, short-swimming fibrous nasal drops with the ability to transport drugs along the nasal mucosa were inno

Updated on:April 28,2024

COVID-19 infection rates low in people with rheumatic diseases, most report mild illness

by American College of RheumatologyCredit: CC0 Public DomainA new study shows that the COVID-19 infection incidence has been low in people with rheumatic diseases, and most of those infected expe

Updated on: May 23,2024

COVID-19 infection rates low in people with rheumatic diseases, most report mild illness

by American College of RheumatologyCredit: CC0 Public DomainA new study shows that the COVID-19 infection incidence has been low in people with rheumatic diseases, and most of those infected expe

Updated on:May 23,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on: May 07,2024

A metabolic enzyme as a potential new target for cancer immune therapies

by German Cancer Research CenterCredit: Unsplash/CC0 Public DomainThe metabolic enzyme IL4I1 (Interleukin-4-Induced-1) promotes the spread of tumor cells and suppresses the immune system. This wa

Updated on:May 07,2024