JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on: April 16,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on:April 16,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on: May 05,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on:May 05,2024

Paradigm shift: How a risk-based program is changing health care use and outcomes for children with high-risk asthma

by Le Bonheur Children's HospitalCredit: Pixabay/CC0 Public DomainLe Bonheur Children's Hospital's risk-based innovation program Changing High-Risk Asthma in Memphis through Partnership (C

Updated on: March 07,2024

Paradigm shift: How a risk-based program is changing health care use and outcomes for children with high-risk asthma

by Le Bonheur Children's HospitalCredit: Pixabay/CC0 Public DomainLe Bonheur Children's Hospital's risk-based innovation program Changing High-Risk Asthma in Memphis through Partnership (C

Updated on:March 07,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on: March 07,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on:March 07,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on: November 24,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on:November 24,2024

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi

Updated on: April 09,2024

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi

Updated on:April 09,2024

Rheumatologist recommends patients receive pneumococcal vaccine

by UT Southwestern Medical CenterA pneumococcal vaccine is recommended for all patients with rheumatic disorders. Credit: UT Southwestern Medical CenterPatients with rheumatoid arthritis, lupus,

Updated on: June 01,2024

Rheumatologist recommends patients receive pneumococcal vaccine

by UT Southwestern Medical CenterA pneumococcal vaccine is recommended for all patients with rheumatic disorders. Credit: UT Southwestern Medical CenterPatients with rheumatoid arthritis, lupus,

Updated on:June 01,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on: April 16,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on:April 16,2024

New prediction model could help inform patients of their risks of having shoulder replacement surgery

byUniversity of OxfordCredit: Pixabay/CC0 Public DomainA new model to predict the risk of serious complications after shoulder replacement surgery has been developed in a collaboration between r

Updated on: August 08,2024

New prediction model could help inform patients of their risks of having shoulder replacement surgery

byUniversity of OxfordCredit: Pixabay/CC0 Public DomainA new model to predict the risk of serious complications after shoulder replacement surgery has been developed in a collaboration between r

Updated on:August 08,2024

Researchers discover potential new approach to treating psoriatic joint inflammation

by UC DavisCredit: CC0 Public DomainAn international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory

Updated on: June 17,2024

Researchers discover potential new approach to treating psoriatic joint inflammation

by UC DavisCredit: CC0 Public DomainAn international team of researchers, led by UC Davis Health, has developed a new therapeutic approach to treating psoriatic arthritis, a chronic inflammatory

Updated on:June 17,2024

Recurrent wheezing in children linked to 'silent' viral infections

by Josh Barney,University of VirginiaNearly a quarter of children with recurrent wheezing suffer from lung infections that present no symptoms and should be treated with antiviral medications, U

Updated on: August 08,2024

Recurrent wheezing in children linked to 'silent' viral infections

by Josh Barney,University of VirginiaNearly a quarter of children with recurrent wheezing suffer from lung infections that present no symptoms and should be treated with antiviral medications, U

Updated on:August 08,2024

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p

Updated on: April 09,2024

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p

Updated on:April 09,2024