Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on: July 02,2024

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on:July 02,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on: May 08,2024

Pretreatment with TNF inhibitors may improve outcomes of combination cancer immunotherapy

by Universidad de NavarraStudy proposes a new therapeutic approach against cancer that dissociates efficacy and toxicity in the use of combined immunotherapy in animal models. This clinical strat

Updated on:May 08,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on: November 24,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on:November 24,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on: May 05,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on:May 05,2024

How salt can trigger inflammation in multiple sclerosis

by Bill Hathaway,Yale UniversityCredit: CC0 Public DomainResearchers at Yale have identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis (

Updated on: April 16,2024

How salt can trigger inflammation in multiple sclerosis

by Bill Hathaway,Yale UniversityCredit: CC0 Public DomainResearchers at Yale have identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis (

Updated on:April 16,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on: April 10,2024

Study of T cells from COVID-19 convalescents guides vaccine strategies

by The Korea Advanced Institute of Science and Technology (KAIST)Overview of the SARS-CoV-2-specific immune response kinetics. Memory T cells are maintained after recovery from COVID-19 with the

Updated on:April 10,2024

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on: April 17,2024

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on:April 17,2024

mRNA-1273 induces stronger response than BNT162b2 for immunosuppressed

For immunosuppressed patients, mRNA-1273 induces a stronger seroresponse than BNT162b2, according to a research letter published online May 16 inJAMA Network Open.Jonathan Mitchell, M.B.B.S., fr

Updated on: April 20,2024

mRNA-1273 induces stronger response than BNT162b2 for immunosuppressed

For immunosuppressed patients, mRNA-1273 induces a stronger seroresponse than BNT162b2, according to a research letter published online May 16 inJAMA Network Open.Jonathan Mitchell, M.B.B.S., fr

Updated on:April 20,2024

tRNA fragments are involved in poststroke immune reactions

by Goethe University Frankfurt am MainCredit: Pixabay/CC0 Public DomainSebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinf

Updated on: April 24,2024

tRNA fragments are involved in poststroke immune reactions

by Goethe University Frankfurt am MainCredit: Pixabay/CC0 Public DomainSebastian Lobentanzer of Goethe University, Frankfurt, has been studying small RNA dynamics in various contexts using bioinf

Updated on:April 24,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on: May 08,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on:May 08,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on: March 07,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on:March 07,2024

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on: April 20,2024

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on:April 20,2024