A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on: May 05,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on:May 05,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on: April 08,2024

New insight into when CAR T is effective against childhood leukemia

by University College LondonA Wright's stained bone marrow aspirate smear of patient with precursor B-cell acute lymphoblastic leukemia. Credit: VashiDonsk/Wikimedia/CC BY-SA 3.0Scientists an

Updated on:April 08,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on: March 07,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on:March 07,2024

Paradigm shift: How a risk-based program is changing health care use and outcomes for children with high-risk asthma

by Le Bonheur Children's HospitalCredit: Pixabay/CC0 Public DomainLe Bonheur Children's Hospital's risk-based innovation program Changing High-Risk Asthma in Memphis through Partnership (C

Updated on: March 07,2024

Paradigm shift: How a risk-based program is changing health care use and outcomes for children with high-risk asthma

by Le Bonheur Children's HospitalCredit: Pixabay/CC0 Public DomainLe Bonheur Children's Hospital's risk-based innovation program Changing High-Risk Asthma in Memphis through Partnership (C

Updated on:March 07,2024

New prediction model could help inform patients of their risks of having shoulder replacement surgery

byUniversity of OxfordCredit: Pixabay/CC0 Public DomainA new model to predict the risk of serious complications after shoulder replacement surgery has been developed in a collaboration between r

Updated on: August 08,2024

New prediction model could help inform patients of their risks of having shoulder replacement surgery

byUniversity of OxfordCredit: Pixabay/CC0 Public DomainA new model to predict the risk of serious complications after shoulder replacement surgery has been developed in a collaboration between r

Updated on:August 08,2024

Recurrent wheezing in children linked to 'silent' viral infections

by Josh Barney,University of VirginiaNearly a quarter of children with recurrent wheezing suffer from lung infections that present no symptoms and should be treated with antiviral medications, U

Updated on: August 08,2024

Recurrent wheezing in children linked to 'silent' viral infections

by Josh Barney,University of VirginiaNearly a quarter of children with recurrent wheezing suffer from lung infections that present no symptoms and should be treated with antiviral medications, U

Updated on:August 08,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on: April 16,2024

JAK signaling may be behind polymyalgia rheumatica

by Lori SolomonJanus tyrosine kinase (JAK) signaling may be involved in the pathogenesis of polymyalgia rheumatica (PMR), and tofacitinib may be an effective treatment, according to a pilot study publ

Updated on:April 16,2024

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on: April 08,2024

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on:April 08,2024

Patients with rheumatoid arthritis have increased anxiety during pandemic

For patients with rheumatoid arthritis (RA), anxiety increased during the COVID-19 pandemic, as did suspected depression, according to a letter to the editor published online Jan. 27 inRheumatol

Updated on: June 28,2024

Patients with rheumatoid arthritis have increased anxiety during pandemic

For patients with rheumatoid arthritis (RA), anxiety increased during the COVID-19 pandemic, as did suspected depression, according to a letter to the editor published online Jan. 27 inRheumatol

Updated on:June 28,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on: April 16,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on:April 16,2024

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi

Updated on: April 09,2024

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi

Updated on:April 09,2024

Pain and fatigue in rheumatoid arthritis tied to sitting and standing time

For patients with rheumatoid arthritis (RA), pain and fatigue may both cause and be caused by more sitting time and less standing time, according to a study published in the October issue ofRheu

Updated on: June 17,2024

Pain and fatigue in rheumatoid arthritis tied to sitting and standing time

For patients with rheumatoid arthritis (RA), pain and fatigue may both cause and be caused by more sitting time and less standing time, according to a study published in the October issue ofRheu

Updated on:June 17,2024