How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on: March 27,2024

How the body's immune response to bacterial infections could cause detrimental inflammation

byNanyang Technological UniversityA. Representative images of A549-ASC-GFP-NLRP1 (upper panel) or ZAKɑ KO A549-ASCGFP-NLRP1 (lower panel) reporter cells Images of GFP and DAPI fluorescence were

Updated on:March 27,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on: April 16,2024

The positive and negative role of LRH-1 during inflammation

by University of KonstanzDetection of immune cells using specific antibodies in tissue sections of the spleen of wild type animals (left panel) and mice with T cell-specific deletion of LRH-1 (ri

Updated on:April 16,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on: May 05,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on:May 05,2024

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p

Updated on: April 09,2024

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p

Updated on:April 09,2024

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on: April 08,2024

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Updated on:April 08,2024

CAR NKT cells offer a promising novel immunotherapy for solid tumors

by Molly Chiu,Baylor College of MedicineCredit: CC0 Public DomainNatural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have b

Updated on: April 08,2024

CAR NKT cells offer a promising novel immunotherapy for solid tumors

by Molly Chiu,Baylor College of MedicineCredit: CC0 Public DomainNatural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have b

Updated on:April 08,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on: May 08,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on:May 08,2024

Gene variant tied to risk for interstitial lung disease in RA

(HealthDay)—For patients with rheumatoid arthritis (RA), theMUC5Bvariant is associated with an increased risk for RA-associated interstitial lung disease (ILD), according to a study publis

Updated on: June 26,2024

Gene variant tied to risk for interstitial lung disease in RA

(HealthDay)—For patients with rheumatoid arthritis (RA), theMUC5Bvariant is associated with an increased risk for RA-associated interstitial lung disease (ILD), according to a study publis

Updated on:June 26,2024

1 billion people worldwide will suffer from arthritis by 2050

by Cara MurezThe degenerative joint disease osteoarthritis affects 15% of the global population over age 30, so by 2050 that could be nearly 1 billion people, researchers say.Living longer and obesity

Updated on: May 08,2024

1 billion people worldwide will suffer from arthritis by 2050

by Cara MurezThe degenerative joint disease osteoarthritis affects 15% of the global population over age 30, so by 2050 that could be nearly 1 billion people, researchers say.Living longer and obesity

Updated on:May 08,2024

Delivery methods compared for osteoarthritis intervention

First-line intervention for hip or knee osteoarthritis (OA) may reduce pain whether delivered in-person or digitally, according to a study published online Nov. 3 inJAMA Network Open.Therese Jön

Updated on: May 29,2024

Delivery methods compared for osteoarthritis intervention

First-line intervention for hip or knee osteoarthritis (OA) may reduce pain whether delivered in-person or digitally, according to a study published online Nov. 3 inJAMA Network Open.Therese Jön

Updated on:May 29,2024

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on: April 20,2024

Mpox: Characterization of post-infectious immune response

by Pasteur InstituteHuman cells infected with MPXV (in green) among uninfected cells (nuclei in blue). Image taken with a confocal microscope. Credit: Mathieu Hubert and Olivier Schwartz, Institu

Updated on:April 20,2024

Prevalence of knee OA lower with menopausal hormone therapy

(HealthDay)—For postmenopausal women, the prevalence of knee osteoarthritis is lower with menopausal hormone therapy (MHT) use, according to a study published online Dec. 21 inMenopause.Jae Hyun

Updated on: May 26,2024

Prevalence of knee OA lower with menopausal hormone therapy

(HealthDay)—For postmenopausal women, the prevalence of knee osteoarthritis is lower with menopausal hormone therapy (MHT) use, according to a study published online Dec. 21 inMenopause.Jae Hyun

Updated on:May 26,2024