T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on: November 24,2024

T-cell dysfunction increases cancer risk in obese populations, researchers say

bySaint Louis UniversityCD8+T cell dysfunction in the obese tumor microenvironment. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-47359-5Researchers at Saint Loui

Updated on:November 24,2024

CAR NKT cells offer a promising novel immunotherapy for solid tumors

by Molly Chiu,Baylor College of MedicineCredit: CC0 Public DomainNatural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have b

Updated on: April 08,2024

CAR NKT cells offer a promising novel immunotherapy for solid tumors

by Molly Chiu,Baylor College of MedicineCredit: CC0 Public DomainNatural killer T (NKT) cells, a type of immune cells known for their potent anti-cancer properties in murine tumor models, have b

Updated on:April 08,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on: March 07,2024

An AI strategy for identifying new immunotherapy targets

by Cleveland ClinicSlowest relaxation timescales estimated by unsupervised AI highlight concerted MHC–peptide dynamics and multiple peptide presentation modes. Credit:Briefings in Bioinform

Updated on:March 07,2024

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on: April 17,2024

Severe reaction to pneumococcal vaccines in patients with CAPS

(HealthDay)—Pneumococcal vaccines can trigger a severe local and systemic inflammatory reaction in patients with cryopyrin-associated periodic syndromes (CAPS), according to a study published in the F

Updated on:April 17,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on: May 05,2024

A pan-cancer platform to help guide patient selection for personalized immunotherapy

by Vall d'Hebron Institute of OncologyGraphical Abstract. Credit:Med(2023). DOI: 10.1016/j.medj.2023.07.006Immunotherapy is a type of cancer treatment that boosts the immune syste

Updated on:May 05,2024

Paradigm shift: How a risk-based program is changing health care use and outcomes for children with high-risk asthma

by Le Bonheur Children's HospitalCredit: Pixabay/CC0 Public DomainLe Bonheur Children's Hospital's risk-based innovation program Changing High-Risk Asthma in Memphis through Partnership (C

Updated on: March 07,2024

Paradigm shift: How a risk-based program is changing health care use and outcomes for children with high-risk asthma

by Le Bonheur Children's HospitalCredit: Pixabay/CC0 Public DomainLe Bonheur Children's Hospital's risk-based innovation program Changing High-Risk Asthma in Memphis through Partnership (C

Updated on:March 07,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on: April 15,2024

Analysis of DNA reveals weapons used by our immune cells to fight tuberculosis

by Agency for Science, Technology and Research (A*STAR), SingaporeFig. 1: Histone acetylome-wide association study of TB. Credit: DOI: 10.1038/s41564-021-01049-wA study led by the Agency for Scie

Updated on:April 15,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on: May 30,2024

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on:May 30,2024

Physical activity reduces cardiovascular risk in rheumatic patients

by FAPESPPeople with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that re

Updated on: June 26,2024

Physical activity reduces cardiovascular risk in rheumatic patients

by FAPESPPeople with diseases such as rheumatoid arthritis and lupus are more likely to have heart attacks, angina, and strokes. A review of the scientific literature on the subject shows that re

Updated on:June 26,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on: May 08,2024

Study finds half of patients with low-grade proteinuria develop treatable lupus nephritis within two years

by American College of RheumatologyCredit: Short- and Long-Term Progression of Kidney Involvement in Systemic Lupus Erythematosus Patients with Low-Grade Proteinuria (2022) https://acrabstracts.o

Updated on:May 08,2024

Pain and fatigue in rheumatoid arthritis tied to sitting and standing time

For patients with rheumatoid arthritis (RA), pain and fatigue may both cause and be caused by more sitting time and less standing time, according to a study published in the October issue ofRheu

Updated on: June 17,2024

Pain and fatigue in rheumatoid arthritis tied to sitting and standing time

For patients with rheumatoid arthritis (RA), pain and fatigue may both cause and be caused by more sitting time and less standing time, according to a study published in the October issue ofRheu

Updated on:June 17,2024

The role of T-cells in SARS-CoV-2 virus defense

by Universitaet TübingenA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDOur immune system can efficiently fend off viral diseases. T-cells can directly destroy viru

Updated on: May 05,2024

The role of T-cells in SARS-CoV-2 virus defense

by Universitaet TübingenA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDOur immune system can efficiently fend off viral diseases. T-cells can directly destroy viru

Updated on:May 05,2024