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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
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Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli

Serum IL-35 levels tied to bone loss with rheumatoid arthritis

Serum interleukin (IL)-35 levels are associated with bone loss and may represent a novel therapeutic target for postmenopausal women with rheumatoid arthritis (RA), according to a study published onli
Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect

Nrf2: The custodian regulating oxidative stress and immunity against acrylamide toxicity

by Tokyo University of ScienceGenetic ablation of Nrf2 exacerbates neurotoxic effects of acrylamide in mice. Credit: Tokyo University of ScienceAcrylamide is a toxic chemical compound that affect
AID/APOBECs among important factors in body's defence against SARS-CoV-2

AID/APOBECs among important factors in body's defence against SARS-CoV-2

by Johannes Angerer,Medical University of ViennaCredit: Unsplash/CC0 Public DomainTogether with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called AP

AID/APOBECs among important factors in body's defence against SARS-CoV-2

by Johannes Angerer,Medical University of ViennaCredit: Unsplash/CC0 Public DomainTogether with their multifaceted action mechanisms, activation-induced cytidine deaminase (AID) and so-called AP
Cryo-EM imaging of STING protein reveals new binding pocket

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at

Cryo-EM imaging of STING protein reveals new binding pocket

by UniversityofTexasSouthwesternMedicalCenterThe synthetic drug-like compound (magenta spheres at the bottom) targets a hidden pocket in STING. This pocket is located at
Scientists discover possible target for treating and preventing osteoarthritis

Scientists discover possible target for treating and preventing osteoarthritis

by University of FloridaCredit: CC0 Public DomainWear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis. Scientists at UF Scripps Biomedical Re

Scientists discover possible target for treating and preventing osteoarthritis

by University of FloridaCredit: CC0 Public DomainWear and tear on joints can lead to inflammation, breakdown of cartilage and development of osteoarthritis. Scientists at UF Scripps Biomedical Re
B cells gone bad could be the culprit in rheumatoid arthritis

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell

B cells gone bad could be the culprit in rheumatoid arthritis

by Laurie Fickman,University of HoustonBiomolecular researcher Navin Varadarajan anticipates that his data will serve as a foundation for investigating multiple hypotheses on the roles of B cell
Novel study identifies key molecular players in rheumatoid arthritis

Novel study identifies key molecular players in rheumatoid arthritis

by University of California - San DiegoAn x-ray depicts a hand fully affected by rheumatoid arthritis, which is characterized by swollen, painful joints, most commonly involving the wrists and ha

Novel study identifies key molecular players in rheumatoid arthritis

by University of California - San DiegoAn x-ray depicts a hand fully affected by rheumatoid arthritis, which is characterized by swollen, painful joints, most commonly involving the wrists and ha
Guidance for coronary patients with ASA/NSAID sensitivity

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI

Guidance for coronary patients with ASA/NSAID sensitivity

(HealthDay)—In patients with stable chronic ischemic heart disease (CIHD) and histories of nonsevere hypersensitivity reactions to acetylsalicylic acid (ASA)/nonsteroidal anti-inflammatory drugs (NSAI
A new cause of osteoarthritis identified by research on a rare disease

A new cause of osteoarthritis identified by research on a rare disease

by University of LiverpoolMicro CT scan of the head of a femur (thigh bone) showing the presence of sharp HDMPs on the surface of the bone." Credit: University of LiverpoolA new mechanism of

A new cause of osteoarthritis identified by research on a rare disease

by University of LiverpoolMicro CT scan of the head of a femur (thigh bone) showing the presence of sharp HDMPs on the surface of the bone." Credit: University of LiverpoolA new mechanism of
How salt can trigger inflammation in multiple sclerosis

How salt can trigger inflammation in multiple sclerosis

by Bill Hathaway,Yale UniversityCredit: CC0 Public DomainResearchers at Yale have identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis (

How salt can trigger inflammation in multiple sclerosis

by Bill Hathaway,Yale UniversityCredit: CC0 Public DomainResearchers at Yale have identified a high-salt environment as one of the contributing factors to the development of multiple sclerosis (
Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la
Lithium may protect against cartilage decline in osteoarthritis

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to

Lithium may protect against cartilage decline in osteoarthritis

(HealthDay)—Lithium reduces catabolic events in interleukin-1 β (IL-1β)-treated human articular chondrocytes and protects against cartilage degradation in IL-1β-treated mouse knee joints, according to