Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on: May 08,2024 8

Differences in T cells' functional state determine resistance to cancer therapy

by Massachusetts Institute of TechnologyThe researchers took this image of a tumor using immunofluorescence, a technique that allows them to stain tissue sections with fluorescently-labeled antib

Updated on:May 08,2024 8

Genetic key to lupus shows potential of personalised medicine

by Australian National UniversityDr Julia Ellyard(Medical Xpress)—Medical researchers have used DNA sequencing to identify a gene variant responsible for causing lupus in a young patient.The deve

Updated on: June 15,2024 5

Genetic key to lupus shows potential of personalised medicine

by Australian National UniversityDr Julia Ellyard(Medical Xpress)—Medical researchers have used DNA sequencing to identify a gene variant responsible for causing lupus in a young patient.The deve

Updated on:June 15,2024 5

MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases

by Public Library of ScienceProject design and overall conclusions of the St George’s, University of London and University of Oxford collaboration on immune parameters of ICU COVID-19 and severe

Updated on: April 20,2024 11

MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases

by Public Library of ScienceProject design and overall conclusions of the St George’s, University of London and University of Oxford collaboration on immune parameters of ICU COVID-19 and severe

Updated on:April 20,2024 11

Study: Rheumatoid arthritis plus depression may be deadly

Risk of mood-related mortality greater for men.(HealthDay)—People with rheumatoid arthritis have higher-than-normal rates of depression, which could increase their risk of death, according to a new st

Updated on: March 24,2024 11

Study: Rheumatoid arthritis plus depression may be deadly

Risk of mood-related mortality greater for men.(HealthDay)—People with rheumatoid arthritis have higher-than-normal rates of depression, which could increase their risk of death, according to a new st

Updated on:March 24,2024 11

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on: April 24,2024 16

Key type of immune cell 'self-renews' in humans, new study finds

by Cardiff UniversityCredit: CC0 Public DomainA team of scientists has shown that a key type of immune cell "self-renews" in humans.It is an unexpected discovery, as it was previously t

Updated on:April 24,2024 16

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on: March 27,2024 0

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on:March 27,2024 0

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on: April 07,2024 20

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on:April 07,2024 20

New insights on B cells: Researchers explore building better antibodies and curbing autoimmune diseases

by Nancy Fliesler,Harvard Medical SchoolGb3 drives affinity and diversity of antibody responses and protects against viral infection. Credit:Science(2024). DOI: 10.1126/science.adg05

Updated on: April 28,2024 0

New insights on B cells: Researchers explore building better antibodies and curbing autoimmune diseases

by Nancy Fliesler,Harvard Medical SchoolGb3 drives affinity and diversity of antibody responses and protects against viral infection. Credit:Science(2024). DOI: 10.1126/science.adg05

Updated on:April 28,2024 0

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play

Updated on: April 16,2024 10

How IL-33 plays a key role in enabling the marathon runners of the immune system

by University of BaselGraphical abstract. Credit:Immunity(2023). DOI: 10.1016/j.immuni.2023.01.029When it comes to chronic infections and cancer, a particular type of immune cell play

Updated on:April 16,2024 10

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025 0

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025 0

New drug expands treatment opportunities for rheumatoid arthritis

by Medical University of ViennaCredit: Unsplash/CC0 Public DomainIn its final Phase III clinical trial, a new drug for treating rheumatoid arthritis has proved to be at least as effective as the

Updated on: June 26,2024 8

New drug expands treatment opportunities for rheumatoid arthritis

by Medical University of ViennaCredit: Unsplash/CC0 Public DomainIn its final Phase III clinical trial, a new drug for treating rheumatoid arthritis has proved to be at least as effective as the

Updated on:June 26,2024 8

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on: April 28,2024 0

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on:April 28,2024 0