CRISPR study reveals new immune system regulators

by Wellcome Trust Sanger InstituteCRISPR-associated protein Cas9 (white) from Staphylococcus aureus based on Protein Database ID 5AXW. Credit: Thomas Splettstoesser (Wikipedia, CC BY-SA 4.0)Scien

Updated on: April 13,2024

CRISPR study reveals new immune system regulators

by Wellcome Trust Sanger InstituteCRISPR-associated protein Cas9 (white) from Staphylococcus aureus based on Protein Database ID 5AXW. Credit: Thomas Splettstoesser (Wikipedia, CC BY-SA 4.0)Scien

Updated on:April 13,2024

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la

Updated on: April 28,2024

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la

Updated on:April 28,2024

COVID-19: The older you are, the more antibodies you have

by University of MontrealA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDWith the emergence of SARS-CoV-2 variants worldwide, the pandemic's spread is accelerat

Updated on: April 10,2024

COVID-19: The older you are, the more antibodies you have

by University of MontrealA colorized scanning electron micrograph of the SARS-CoV-2 virus. Credit: NIAIDWith the emergence of SARS-CoV-2 variants worldwide, the pandemic's spread is accelerat

Updated on:April 10,2024

MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases

by Public Library of ScienceProject design and overall conclusions of the St George’s, University of London and University of Oxford collaboration on immune parameters of ICU COVID-19 and severe

Updated on: April 20,2024

MAIT cell activation may play a role in fatal outcomes among severe COVID-19 cases

by Public Library of ScienceProject design and overall conclusions of the St George’s, University of London and University of Oxford collaboration on immune parameters of ICU COVID-19 and severe

Updated on:April 20,2024

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on: July 02,2024

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on:July 02,2024

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on: June 17,2024

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

Updated on:June 17,2024

Chemical stimuli can support growing of stable cartilage cells

by Umea UniversityRho-kinase inhibition cause disappearance of cellular adhesion sites. The colors of the figure shows the staining for actin stress fibers (red), adhesion plaques-related vinculi

Updated on: May 08,2024

Chemical stimuli can support growing of stable cartilage cells

by Umea UniversityRho-kinase inhibition cause disappearance of cellular adhesion sites. The colors of the figure shows the staining for actin stress fibers (red), adhesion plaques-related vinculi

Updated on:May 08,2024

Sharing of skin microbiome between children with atopic dermatitis and healthy contacts might contribute to recurrence

by National University of SingaporeGraphical abstract. Credit:Journal of Allergy and Clinical Immunology(2022). DOI: 10.1016/j.jaci.2022.01.031Patients with moderate to severe atopic

Updated on: June 12,2024

Sharing of skin microbiome between children with atopic dermatitis and healthy contacts might contribute to recurrence

by National University of SingaporeGraphical abstract. Credit:Journal of Allergy and Clinical Immunology(2022). DOI: 10.1016/j.jaci.2022.01.031Patients with moderate to severe atopic

Updated on:June 12,2024

Cell-compressing technique a new path in immunotherapy

by Zach Winn,Massachusetts Institute of TechnologyTo engineer cell functions, SQZ Biotech uses tiny channels on a microfluidic chip to squeeze cells so they can be penetrated by specific molecul

Updated on: April 09,2024

Cell-compressing technique a new path in immunotherapy

by Zach Winn,Massachusetts Institute of TechnologyTo engineer cell functions, SQZ Biotech uses tiny channels on a microfluidic chip to squeeze cells so they can be penetrated by specific molecul

Updated on:April 09,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on: June 26,2024

Study of infants and young children shows that offspring develop normally in mothers with rheumatic disease

by European League Against Rheumatism (EULAR)Credit: CC0 Public DomainAnkylosing spondylitis (AS) is a complex chronic inflammatory disease of the spine with involvement of the sacroiliac joints. Over

Updated on:June 26,2024

Rheumatism drug also effective at half dose

by Medical University of ViennaThe treatment of moderately active rheumatoid arthritis with the tumour necrosis factor inhibitor Etanercept achieves excellent success in more than 80 per cent of

Updated on: March 24,2024

Rheumatism drug also effective at half dose

by Medical University of ViennaThe treatment of moderately active rheumatoid arthritis with the tumour necrosis factor inhibitor Etanercept achieves excellent success in more than 80 per cent of

Updated on:March 24,2024

COVID-19 can cause severe inflammation in the brain

by Albert Ludwigs University of FreiburgGraphical Abstract. Credit:Immunity(2021). DOI: 10.1016/j.immuni.2021.06.002Both during and after infection with the Coronavirus SARS-CoV-2, pa

Updated on: April 10,2024

COVID-19 can cause severe inflammation in the brain

by Albert Ludwigs University of FreiburgGraphical Abstract. Credit:Immunity(2021). DOI: 10.1016/j.immuni.2021.06.002Both during and after infection with the Coronavirus SARS-CoV-2, pa

Updated on:April 10,2024