Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on: June 26,2024

Continuation vs. discontinuation of bDMARDs during the perioperative period

by Wolters Kluwer HealthCredit: Pixabay/CC0 Public DomainFor patients with rheumatic arthritis and other chronic inflammatory diseases, discontinuing biologic disease-modifying anti-rheumatic dru

Updated on:June 26,2024

Recognizing young people's perspectives in inflammatory arthritis

by EULARFigure 1 Example outlining the different steps of the analysis from a meaning unit to lower and higher level concepts. PROMs, patient-reported outcome measures.Inflammatory arthritis is the na

Updated on: May 26,2024

Recognizing young people's perspectives in inflammatory arthritis

by EULARFigure 1 Example outlining the different steps of the analysis from a meaning unit to lower and higher level concepts. PROMs, patient-reported outcome measures.Inflammatory arthritis is the na

Updated on:May 26,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on: October 10,2024

Here's why B cells benefit from booster shots

byRockefeller UniversityRecall germinal centers formed in response to a secondary infection generate a second line of defense, rebuffing memory B cells in favor of training naive ones. Credit: R

Updated on:October 10,2024

App to monitor rheumatoid arthritis symptoms does not improve disease outcomes

(HealthDay)—Use of a smartphone application (app) to monitor patient-reported outcomes does not improve satisfaction or disease outcomes in rheumatoid arthritis (RA), but patients are likely to recomm

Updated on: May 29,2024

App to monitor rheumatoid arthritis symptoms does not improve disease outcomes

(HealthDay)—Use of a smartphone application (app) to monitor patient-reported outcomes does not improve satisfaction or disease outcomes in rheumatoid arthritis (RA), but patients are likely to recomm

Updated on:May 29,2024

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on: April 08,2024

How B cells are programmed early in life can impact long-term immune health

by Lund UniversityGraphical abstract. Credit:Immunity(2022). DOI: 10.1016/j.immuni.2022.08.018B cells and the antibodies they produce play an important role in our immune system, prot

Updated on:April 08,2024

BEAT-HIV Delaney collaboratory issues recommendations measuring persistent HIV reservoirs

by The Wistar InstituteL-R: Wistar Drs. Mohamed Abdel-Mohsen and Luis Montaner Credit: The Wistar InstituteSpearheaded by scientists at The Wistar Institute, top worldwide HIV researchers from th

Updated on: April 08,2024

BEAT-HIV Delaney collaboratory issues recommendations measuring persistent HIV reservoirs

by The Wistar InstituteL-R: Wistar Drs. Mohamed Abdel-Mohsen and Luis Montaner Credit: The Wistar InstituteSpearheaded by scientists at The Wistar Institute, top worldwide HIV researchers from th

Updated on:April 08,2024

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la

Updated on: April 28,2024

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la

Updated on:April 28,2024

Acoustic technique developed to detect knee osteoarthritis

by Lancaster UniversityA revolutionary medical technique using sound waves to identify osteoarthritis in the knee has been developed by researchers. The UK is leading this new field of&nbsp

Updated on: April 20,2024

Acoustic technique developed to detect knee osteoarthritis

by Lancaster UniversityA revolutionary medical technique using sound waves to identify osteoarthritis in the knee has been developed by researchers. The UK is leading this new field of&nbsp

Updated on:April 20,2024

Researchers identify new target for rheumatoid arthritis

by Hospital for Special SurgeryCo-senior author and Program Director Carl Blobel, M.D., Ph.D., works with collaborator Lionel Ivashkiv, M.D., in the Arthritis and Tissue Degeneration Program lab

Updated on: March 24,2024

Researchers identify new target for rheumatoid arthritis

by Hospital for Special SurgeryCo-senior author and Program Director Carl Blobel, M.D., Ph.D., works with collaborator Lionel Ivashkiv, M.D., in the Arthritis and Tissue Degeneration Program lab

Updated on:March 24,2024

T-cell molecule could be the key to more effective virus and cancer treatments

by Julia Short,Cardiff UniversityScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDResearchers at Cardiff Univer

Updated on: May 07,2024

T-cell molecule could be the key to more effective virus and cancer treatments

by Julia Short,Cardiff UniversityScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDResearchers at Cardiff Univer

Updated on:May 07,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on: April 13,2024

COVID-19 vaccines produce antibody response in the nasal mucosa

by University of North Carolina Health CarePre-immunity and post-immunity SARS-CoV-2 virus-specific IgG and IgA antibody concentrations in NELF and serum. Antibody concentrations were reported as

Updated on:April 13,2024