Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on: January 11,2025 0

Loosening chimeric antigen receptor's grip on T-regulatory cells improves function, researchers find

by Leslie Cantu,Medical University of South CarolinaCAR and endogenous TCR/CD28 activation result in phenotypically similar Tregs. Credit:Molecular Therapy—Methods & Clinical Developme

Updated on:January 11,2025 0

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on: April 28,2024 0

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on:April 28,2024 0

How to keep kids with food allergies safe during Halloween

by Jason HowlandCredit: Unsplash/CC0 Public DomainHalloween can be a particularly difficult time for kids with food allergies since many common candies contain one or more common allergens. The conseq

Updated on: June 25,2024 7

How to keep kids with food allergies safe during Halloween

by Jason HowlandCredit: Unsplash/CC0 Public DomainHalloween can be a particularly difficult time for kids with food allergies since many common candies contain one or more common allergens. The conseq

Updated on:June 25,2024 7

How changing gut microbiota can affect lupus disease activity in mice

by The Ohio State UniversityFigure 1. NZM2410 colonized with SFB exhibit intensified kidney disease with elevated immune-complex deposition. 10-week old mice were oral gavaged with fecal matter f

Updated on: June 20,2024 3

How changing gut microbiota can affect lupus disease activity in mice

by The Ohio State UniversityFigure 1. NZM2410 colonized with SFB exhibit intensified kidney disease with elevated immune-complex deposition. 10-week old mice were oral gavaged with fecal matter f

Updated on:June 20,2024 3

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on: April 07,2024 20

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on:April 07,2024 20

A year of COVID-19 lockdown is putting kids at risk of allergies, asthma and autoimmune diseases

by Byram W. Bridle,The ConversationCredit: Unsplash/CC0 Public Domain"Eat dirt!" is a phrase I remember well. It was in thetitle of an articlepublished by Harvard Universit

Updated on: May 07,2024 13

A year of COVID-19 lockdown is putting kids at risk of allergies, asthma and autoimmune diseases

by Byram W. Bridle,The ConversationCredit: Unsplash/CC0 Public Domain"Eat dirt!" is a phrase I remember well. It was in thetitle of an articlepublished by Harvard Universit

Updated on:May 07,2024 13

Study finds TNF inhibitor more effective with regular serum assessment to adjust dose

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that pro

Updated on: June 28,2024 5

Study finds TNF inhibitor more effective with regular serum assessment to adjust dose

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that pro

Updated on:June 28,2024 5

Inactivity and obesity relate to cognitive impairment in lupus

(HealthDay) -- Physical inactivity and obesity are associated with impaired cognitive function, especially executive functions, in women with systemic lupus erythematosus (SLE), according to research

Updated on: April 08,2024 20

Inactivity and obesity relate to cognitive impairment in lupus

(HealthDay) -- Physical inactivity and obesity are associated with impaired cognitive function, especially executive functions, in women with systemic lupus erythematosus (SLE), according to research

Updated on:April 08,2024 20

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on: March 27,2024 0

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on:March 27,2024 0

Acoustic technique developed to detect knee osteoarthritis

by Lancaster UniversityA revolutionary medical technique using sound waves to identify osteoarthritis in the knee has been developed by researchers. The UK is leading this new field of&nbsp

Updated on: April 20,2024 15

Acoustic technique developed to detect knee osteoarthritis

by Lancaster UniversityA revolutionary medical technique using sound waves to identify osteoarthritis in the knee has been developed by researchers. The UK is leading this new field of&nbsp

Updated on:April 20,2024 15

Vitamin D shows no impact on interferon response in SLE

(HealthDay)—For patients with systemic lupus erythematosus (SLE), vitamin D3supplementation does not affect interferon (IFN) signature, according to a study published in the July issue ofA

Updated on: April 08,2024 20

Vitamin D shows no impact on interferon response in SLE

(HealthDay)—For patients with systemic lupus erythematosus (SLE), vitamin D3supplementation does not affect interferon (IFN) signature, according to a study published in the July issue ofA

Updated on:April 08,2024 20

New class of molecules play key role in influencing the immune system

by Brigham and Women's HospitalProresolving lipid mediators – resolvin D1 (RvD1), resolvin D2 (RvD2), and maresin 1 (MaR1) – modulate T cell responses. Credit: Valerio Chiurchiu et al., Scien

Updated on: May 05,2024 17

New class of molecules play key role in influencing the immune system

by Brigham and Women's HospitalProresolving lipid mediators – resolvin D1 (RvD1), resolvin D2 (RvD2), and maresin 1 (MaR1) – modulate T cell responses. Credit: Valerio Chiurchiu et al., Scien

Updated on:May 05,2024 17