First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on: April 09,2024

First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on:April 09,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on: May 08,2024

A common metabolite may help treat autoimmune diseases

by Hokkaido UniversityIn mice models with adoptive transfer experimental autoimmune encephalomyelitis, treatment with itaconate (right) greatly ameliorates the effects of the disease, compared to

Updated on:May 08,2024

CAR T therapy shows long-lasting remissions in non-hodgkin lymphoma

by Perelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainA significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical

Updated on: April 08,2024

CAR T therapy shows long-lasting remissions in non-hodgkin lymphoma

by Perelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainA significant number of non-Hodgkin lymphoma (NHL) patients in a Penn Medicine-initiated clinical

Updated on:April 08,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s

Updated on: March 24,2024

Rheumatoid arthritis drug not linked to specific birth defects

The rheumatoid arthritis drug leflunomide is not a major cause of birth defects in women who inadvertently become pregnant while taking the drug, although pregnancy should be avoided, according to a s

Updated on:March 24,2024

A new open-access portal for human immunology data and tools

by Rachel Tompa,Allen Institute for Brain ScienceTEA-seq single panel cell type data from Human Immune System Explorer. Credit: Zach Thomson/Allen InstituteResearchers at the Allen Institute for

Updated on: May 05,2024

A new open-access portal for human immunology data and tools

by Rachel Tompa,Allen Institute for Brain ScienceTEA-seq single panel cell type data from Human Immune System Explorer. Credit: Zach Thomson/Allen InstituteResearchers at the Allen Institute for

Updated on:May 05,2024

Scientists identify reversible molecular defect underlying rheumatoid arthritis

by Bruce Goldman,Stanford University Medical CenterScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn rheumatoid arthritis, immune cells called helper T cells beha

Updated on: June 06,2024

Scientists identify reversible molecular defect underlying rheumatoid arthritis

by Bruce Goldman,Stanford University Medical CenterScanning electron micrograph of human T lymphocyte or T cell. Credit: NIAID/NIHIn rheumatoid arthritis, immune cells called helper T cells beha

Updated on:June 06,2024

Air pollution linked to having a peanut allergy during childhood

byMurdoch Children's Research InstituteCredit: Pixabay/CC0 Public DomainExposure to higher levels of air pollution as a baby is linked to having a peanut allergy throughout childhood, accord

Updated on: November 01,2024

Air pollution linked to having a peanut allergy during childhood

byMurdoch Children's Research InstituteCredit: Pixabay/CC0 Public DomainExposure to higher levels of air pollution as a baby is linked to having a peanut allergy throughout childhood, accord

Updated on:November 01,2024

Proteinuria level predicts renal outcome in lupus nephritis

(HealthDay)—Proteinuria levels at 12 months are the best predictor of long-term renal outcome in patients with lupus nephritis, according to a study published in the May issue ofArthritis &

Updated on: March 24,2024

Proteinuria level predicts renal outcome in lupus nephritis

(HealthDay)—Proteinuria levels at 12 months are the best predictor of long-term renal outcome in patients with lupus nephritis, according to a study published in the May issue ofArthritis &

Updated on:March 24,2024

Adherence to mediterranean diet not linked to risk of RA

(HealthDay)—Adherence to a Mediterranean diet is not associated with incidence of rheumatoid arthritis (RA) in U.S. women, according to a study published in the May issue ofArthritis Care &

Updated on: April 08,2024

Adherence to mediterranean diet not linked to risk of RA

(HealthDay)—Adherence to a Mediterranean diet is not associated with incidence of rheumatoid arthritis (RA) in U.S. women, according to a study published in the May issue ofArthritis Care &

Updated on:April 08,2024

New class of molecules play key role in influencing the immune system

by Brigham and Women's HospitalProresolving lipid mediators – resolvin D1 (RvD1), resolvin D2 (RvD2), and maresin 1 (MaR1) – modulate T cell responses. Credit: Valerio Chiurchiu et al., Scien

Updated on: May 05,2024

New class of molecules play key role in influencing the immune system

by Brigham and Women's HospitalProresolving lipid mediators – resolvin D1 (RvD1), resolvin D2 (RvD2), and maresin 1 (MaR1) – modulate T cell responses. Credit: Valerio Chiurchiu et al., Scien

Updated on:May 05,2024

Patient-Rated elbow evaluation most responsive instrument

The Patient-Rated Elbow Evaluation form is the most responsive instrument to identify and quantify elbow joint-specific changes before and after total elbow arthroplasty, according to a study publishe

Updated on: April 08,2024

Patient-Rated elbow evaluation most responsive instrument

The Patient-Rated Elbow Evaluation form is the most responsive instrument to identify and quantify elbow joint-specific changes before and after total elbow arthroplasty, according to a study publishe

Updated on:April 08,2024