Risankizumab safe, effective at 52 weeks for psoriatic arthritis

by Lori SolomonRisankizumab provides long-term benefits in patients with psoriatic arthritis (PsA) who have not achieved adequate response to previous therapies, according to a study recently publishe

Updated on: June 01,2024

Risankizumab safe, effective at 52 weeks for psoriatic arthritis

by Lori SolomonRisankizumab provides long-term benefits in patients with psoriatic arthritis (PsA) who have not achieved adequate response to previous therapies, according to a study recently publishe

Updated on:June 01,2024

Antibodies in blood soon after COVID-19 onset may predict severity

by Bruce Goldman,Stanford University Medical CenterAn illustration of antlbodies surrounding a virus.Antibodies are proteins shaped, roughly speaking, like two-branched trees. They’re prod

Updated on: April 10,2024

Antibodies in blood soon after COVID-19 onset may predict severity

by Bruce Goldman,Stanford University Medical CenterAn illustration of antlbodies surrounding a virus.Antibodies are proteins shaped, roughly speaking, like two-branched trees. They’re prod

Updated on:April 10,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on: June 15,2024

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Updated on:June 15,2024

Aerobic exercise may cut fatigue in rheumatoid arthritis

(HealthDay)—Aerobic land-based exercise may be helpful in treating fatigue in patients with rheumatoid arthritis (RA), according to a meta-analysis published in the August issue ofArthritis Care

Updated on: March 24,2024

Aerobic exercise may cut fatigue in rheumatoid arthritis

(HealthDay)—Aerobic land-based exercise may be helpful in treating fatigue in patients with rheumatoid arthritis (RA), according to a meta-analysis published in the August issue ofArthritis Care

Updated on:March 24,2024

Inactivity and obesity relate to cognitive impairment in lupus

(HealthDay) -- Physical inactivity and obesity are associated with impaired cognitive function, especially executive functions, in women with systemic lupus erythematosus (SLE), according to research

Updated on: April 08,2024

Inactivity and obesity relate to cognitive impairment in lupus

(HealthDay) -- Physical inactivity and obesity are associated with impaired cognitive function, especially executive functions, in women with systemic lupus erythematosus (SLE), according to research

Updated on:April 08,2024

TNF inhibitors may not modify polyarticular JIA disease process

(HealthDay)—For children with polyarticular juvenile idiopathic arthritis (JIA), discontinuing medications is challenging, with high relapse rates, especially after discontinuation of tumor necrosis f

Updated on: April 08,2024

TNF inhibitors may not modify polyarticular JIA disease process

(HealthDay)—For children with polyarticular juvenile idiopathic arthritis (JIA), discontinuing medications is challenging, with high relapse rates, especially after discontinuation of tumor necrosis f

Updated on:April 08,2024

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la

Updated on: April 28,2024

Respiratory allergies: Newly discovered molecule plays a major role in triggering inflammation

byCNRSMicroscopic visualization of immune cells (in green) activated by the alarmins TL1A and interleukin-33 during the onset of allergic inflammation in the lungs. ILC2s immune cells produce la

Updated on:April 28,2024

Brain activity linked to TNF inhibitor response in RA

Patients with rheumatoid arthritis who respond to tumor necrosis factor inhibitors show changes in activity in pain-related areas of the brain before clinical signs of improvement are observed, accord

Updated on: April 08,2024

Brain activity linked to TNF inhibitor response in RA

Patients with rheumatoid arthritis who respond to tumor necrosis factor inhibitors show changes in activity in pain-related areas of the brain before clinical signs of improvement are observed, accord

Updated on:April 08,2024

Immune cell responses in COVID-19 patients far from optimal

by Doherty Institute for Infection and ImmunityCredit: Thiago Lazarino from PixabayMelbourne researchers have discovered that killer T cells, key immune cells in fighting viral infections, are present

Updated on: April 10,2024

Immune cell responses in COVID-19 patients far from optimal

by Doherty Institute for Infection and ImmunityCredit: Thiago Lazarino from PixabayMelbourne researchers have discovered that killer T cells, key immune cells in fighting viral infections, are present

Updated on:April 10,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on: July 11,2024

Scientists discover two cellular defects appear to drive disease in lupus

byNorthwestern UniversityCredit: Pixabay/CC0 Public DomainNorthwestern Medicine and Brigham and Women's Hospital scientists have discovered a molecular defect that promotes the pathologic im

Updated on:July 11,2024

Identification of LZTR1 leads to novel insights into RAS-driven diseases

by VIB (the Flanders Institute for Biotechnology)Cancer cell during cell division. Credit: National Institutes of HealthMutations in RAS proteins initiate many of the most aggressive tumors, and

Updated on: April 16,2024

Identification of LZTR1 leads to novel insights into RAS-driven diseases

by VIB (the Flanders Institute for Biotechnology)Cancer cell during cell division. Credit: National Institutes of HealthMutations in RAS proteins initiate many of the most aggressive tumors, and

Updated on:April 16,2024

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Updated on: April 20,2024

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Updated on:April 20,2024