Why inflammatory arthritis always recurs in certain joints

by Children's Hospital BostonCredit: Unsplash/CC0 Public DomainWhen joints flare up in people with rheumatoid arthritis and related diseases, the joints involved are often the same as those a

Updated on: June 17,2024 3

Why inflammatory arthritis always recurs in certain joints

by Children's Hospital BostonCredit: Unsplash/CC0 Public DomainWhen joints flare up in people with rheumatoid arthritis and related diseases, the joints involved are often the same as those a

Updated on:June 17,2024 3

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on: May 06,2024 20

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on:May 06,2024 20

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on: May 08,2024 3

Compound found to trigger innate immunity against viruses

by Bobbi Nodell,University of WashingtonCells under a microscope in a UW Medicine immunity lab. Credit: Dennis WiseResearch from UW Medicine and collaborators indicates that a drug-like molecule

Updated on:May 08,2024 3

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on: May 30,2024 0

Study in mice shows alterations in X-chromosome inactivation predispose female mammals to autoimmune disease

by Bob Yirka , Medical XpressPerturbation of X-inactivation in immune cells ofFtx−/−females.(A) Map of the X inactivation center showing the location ofXist(green) andFtx

Updated on:May 30,2024 0

COVID-19 can cause severe inflammation in the brain

by Albert Ludwigs University of FreiburgGraphical Abstract. Credit:Immunity(2021). DOI: 10.1016/j.immuni.2021.06.002Both during and after infection with the Coronavirus SARS-CoV-2, pa

Updated on: April 10,2024 18

COVID-19 can cause severe inflammation in the brain

by Albert Ludwigs University of FreiburgGraphical Abstract. Credit:Immunity(2021). DOI: 10.1016/j.immuni.2021.06.002Both during and after infection with the Coronavirus SARS-CoV-2, pa

Updated on:April 10,2024 18

Identification of LZTR1 leads to novel insights into RAS-driven diseases

by VIB (the Flanders Institute for Biotechnology)Cancer cell during cell division. Credit: National Institutes of HealthMutations in RAS proteins initiate many of the most aggressive tumors, and

Updated on: April 16,2024 14

Identification of LZTR1 leads to novel insights into RAS-driven diseases

by VIB (the Flanders Institute for Biotechnology)Cancer cell during cell division. Credit: National Institutes of HealthMutations in RAS proteins initiate many of the most aggressive tumors, and

Updated on:April 16,2024 14

Major savings possible with app-based osteoarthritis treatment

by Lund UniversityCredit: CC0 Public DomainOsteoarthritis treatment conducted digitally via an app costs around 25% of what conventional care costs, according to a study from Lund University in S

Updated on: April 17,2024 17

Major savings possible with app-based osteoarthritis treatment

by Lund UniversityCredit: CC0 Public DomainOsteoarthritis treatment conducted digitally via an app costs around 25% of what conventional care costs, according to a study from Lund University in S

Updated on:April 17,2024 17

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on: April 20,2024 17

PFAS can suppress white blood cell's ability to destroy invaders

by Tracey Peake,North Carolina State UniversityPFASs used in this study. Names and structures of the PFASs used in this study. Vendors and CAS-RN numbers are provided in Table 1. Chemical struct

Updated on:April 20,2024 17

Does an elevated immune response to a gut bacterial protein contribute to rheumatoid arthritis?

by WileyCredit: Unsplash/CC0 Public DomainRheumatoid arthritis is a chronic autoimmune disease that is associated with aberrant immune responses. In a recent analysis published inArthritis

Updated on: June 15,2024 4

Does an elevated immune response to a gut bacterial protein contribute to rheumatoid arthritis?

by WileyCredit: Unsplash/CC0 Public DomainRheumatoid arthritis is a chronic autoimmune disease that is associated with aberrant immune responses. In a recent analysis published inArthritis

Updated on:June 15,2024 4

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on: April 20,2024 18

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on:April 20,2024 18

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

Updated on: March 24,2024 19

High false negative rate with PFTs in scleroderma lung disease

(HealthDay)—Use of pulmonary function tests (PFTs) is associated with high false negative rates for detection of scleroderma-associated interstitial lung disease (SSc-ILD), according to a study publis

Updated on:March 24,2024 19

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on: April 10,2024 20

How a COVID-19 infection spurs antibodies against common colds

by The Scripps Research InstituteResearchers analyzed the structures of antibodies (colored) from healthy donors as the molecules bound to the spike protein from common coronaviruses like OC43 (s

Updated on:April 10,2024 20