First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on: April 09,2024

First-in-human trial with CAR macrophages shows promise targeting solid tumors

by Caren Begun,University of PennsylvaniaCredit: Pixabay/CC0 Public DomainPreliminary findings from Penn Medicine in an ongoing first-in-human clinical trial examining the safety, tolerability a

Updated on:April 09,2024

T-cell molecule could be the key to more effective virus and cancer treatments

by Julia Short,Cardiff UniversityScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDResearchers at Cardiff Univer

Updated on: May 07,2024

T-cell molecule could be the key to more effective virus and cancer treatments

by Julia Short,Cardiff UniversityScanning electron micrograph of a human T lymphocyte (also called a T cell) from the immune system of a healthy donor. Credit: NIAIDResearchers at Cardiff Univer

Updated on:May 07,2024

Uranium exposure tied to lupus

(HealthDay)—High uranium exposure is associated with systemic lupus erythematosus (SLE), according to a study published online Aug. 7 inArthritis & Rheumatology.Pai-Yue Lu-Fritts, M.D., from

Updated on: March 24,2024

Uranium exposure tied to lupus

(HealthDay)—High uranium exposure is associated with systemic lupus erythematosus (SLE), according to a study published online Aug. 7 inArthritis & Rheumatology.Pai-Yue Lu-Fritts, M.D., from

Updated on:March 24,2024

By better predicting asthma risk, preventive treatments could bypass disease development

by University of ArizonaRespiratory virus prevalence, baseline CBMC cell proportions, multi-omic data set overview. (A) Bar plot of viral agents detected from infectious NPAs taken during year on

Updated on: June 12,2024

By better predicting asthma risk, preventive treatments could bypass disease development

by University of ArizonaRespiratory virus prevalence, baseline CBMC cell proportions, multi-omic data set overview. (A) Bar plot of viral agents detected from infectious NPAs taken during year on

Updated on:June 12,2024

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on: April 07,2024

Five genes tied to osteoarthritis progression

(HealthDay)—Five genes may serve as biomarkers for osteoarthritis (OA) progression, according to a study published online Feb. 2 in theInternational Journal of Rheumatic Diseases.Beiyue Wang, fr

Updated on:April 07,2024

A 'backpack' full of multiple sclerosis therapy

by Benjamin Boettner,Harvard UniversityShown on the left, is an immunofluorescence image of a monocyte with its outer cell membrane stained in green and nucleus stained in blue, and to which the

Updated on: April 24,2024

A 'backpack' full of multiple sclerosis therapy

by Benjamin Boettner,Harvard UniversityShown on the left, is an immunofluorescence image of a monocyte with its outer cell membrane stained in green and nucleus stained in blue, and to which the

Updated on:April 24,2024

PFAS shown to reduce the activity of immune cells

by Helmholtz Association of German Research CentresGraphical abstract. Credit:Chemosphere(2023). DOI: 10.1016/j.chemosphere.2023.139204PFAS are used in many everyday products. This is

Updated on: April 20,2024

PFAS shown to reduce the activity of immune cells

by Helmholtz Association of German Research CentresGraphical abstract. Credit:Chemosphere(2023). DOI: 10.1016/j.chemosphere.2023.139204PFAS are used in many everyday products. This is

Updated on:April 20,2024

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Updated on: May 26,2024

Upadacitinib beats placebo for psoriatic arthritis

For patients with psoriatic arthritis, upadacitinib at a dose of 15 mg or 30 mg once daily is more effective than placebo, according to a study published in the April 1 issue of theNew England J

Updated on:May 26,2024

Rheumatoid arthritis can be costly

Study looked at direct health care spending, worker productivity.(HealthDay)—Workers with rheumatoid arthritis have higher health care and other costs for U.S. employers than workers without the condi

Updated on: March 24,2024

Rheumatoid arthritis can be costly

Study looked at direct health care spending, worker productivity.(HealthDay)—Workers with rheumatoid arthritis have higher health care and other costs for U.S. employers than workers without the condi

Updated on:March 24,2024

New class of molecules play key role in influencing the immune system

by Brigham and Women's HospitalProresolving lipid mediators – resolvin D1 (RvD1), resolvin D2 (RvD2), and maresin 1 (MaR1) – modulate T cell responses. Credit: Valerio Chiurchiu et al., Scien

Updated on: May 05,2024

New class of molecules play key role in influencing the immune system

by Brigham and Women's HospitalProresolving lipid mediators – resolvin D1 (RvD1), resolvin D2 (RvD2), and maresin 1 (MaR1) – modulate T cell responses. Credit: Valerio Chiurchiu et al., Scien

Updated on:May 05,2024

SARS-CoV-2 disrupts timing of immune response

by Charité - Universitätsmedizin BerlinAssay to detect the biochemical messenger TGFβ (COVID-19 research). Credit: Charité | Arne SattlerOnce an infection is under control, the body normally uses

Updated on: April 22,2024

SARS-CoV-2 disrupts timing of immune response

by Charité - Universitätsmedizin BerlinAssay to detect the biochemical messenger TGFβ (COVID-19 research). Credit: Charité | Arne SattlerOnce an infection is under control, the body normally uses

Updated on:April 22,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024