Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on: April 28,2024

Could CAR-T cell therapy improve kidney transplants?

by Susan Buckles, Mayo Clinic News NetworkCredit:Kidney International(2024). DOI: 10.1016/j.kint.2024.02.008Chimeric antigen receptor-T cell therapy (CAR-T cell therapy) could provide a re

Updated on:April 28,2024

New research predicts whether rheumatoid arthritis patients will respond to treatment

by Queen Mary, University of LondonCredit: CC0 Public DomainA new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsive

Updated on: June 17,2024

New research predicts whether rheumatoid arthritis patients will respond to treatment

by Queen Mary, University of LondonCredit: CC0 Public DomainA new study led by researchers at Queen Mary University of London provides potential novel biomarkers for predicting patient responsive

Updated on:June 17,2024

High BMI elevates risk of several rheumatic diseases, but not equally for everyone

by Uppsala UniversityCredit: Pixabay/CC0 Public DomainA new study by Uppsala University shows that a higher body mass index (BMI) increases the risk of five different rheumatic diseases: rheumati

Updated on: June 01,2024

High BMI elevates risk of several rheumatic diseases, but not equally for everyone

by Uppsala UniversityCredit: Pixabay/CC0 Public DomainA new study by Uppsala University shows that a higher body mass index (BMI) increases the risk of five different rheumatic diseases: rheumati

Updated on:June 01,2024

Sensors for a 'smart' wound bandage may track healing, immune response

by Skolkovo Institute of Science and TechnologyCredit: CC0 Public DomainResearchers from Skoltech and the University of Texas at Austin have presented a proof of concept for a wearable sensor tha

Updated on: May 05,2024

Sensors for a 'smart' wound bandage may track healing, immune response

by Skolkovo Institute of Science and TechnologyCredit: CC0 Public DomainResearchers from Skoltech and the University of Texas at Austin have presented a proof of concept for a wearable sensor tha

Updated on:May 05,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on: April 24,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on:April 24,2024

Motion analysis to detect arthrosis

by Karlsruhe Institute of TechnologyMotion Analysis to Detect ArthrosisArthrosis is excessive wear of joints beyond the usual age-related degeneration. For this reason, about 150,000 German

Updated on: March 30,2024

Motion analysis to detect arthrosis

by Karlsruhe Institute of TechnologyMotion Analysis to Detect ArthrosisArthrosis is excessive wear of joints beyond the usual age-related degeneration. For this reason, about 150,000 German

Updated on:March 30,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on: May 08,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on:May 08,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on: June 15,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on:June 15,2024

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on: May 07,2024

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on:May 07,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on: May 29,2024

Rheumatoid arthritis finding may lead to new inflammation blockers

by Sara Tiner,Mayo ClinicCredit: Unsplash/CC0 Public DomainMayo Clinic researchers have linked the T cell dysfunction seen in rheumatoid arthritis with a metabolic deficiency, reported in a new&

Updated on:May 29,2024

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on: July 02,2024

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Updated on:July 02,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on: May 06,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on:May 06,2024