The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on: May 06,2024

The secret lives of T cells: They derive energy from a master regulator that has been poorly understood, until now

by Delthia Ricks , Medical XpressIn vitro modeling of Teff STAT5 responses. (A) WT CD4+ T cells were cultured with or without blocking anti-mouse IL-2/IL-2R antibodies and/or human IL-2. Flow cytometr

Updated on:May 06,2024

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo

Updated on: November 01,2024

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo

Updated on:November 01,2024

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on: April 08,2024

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Updated on:April 08,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

Could painkillers be hiding serious arthritis condition from doctors?

by Euan Wemyss,University of AberdeenCould anti-inflammatory drugs be masking serious arthritis condition, University of Aberdeen to explore. Credit: University of AberdeenThousands of patients

Updated on: March 24,2024

Could painkillers be hiding serious arthritis condition from doctors?

by Euan Wemyss,University of AberdeenCould anti-inflammatory drugs be masking serious arthritis condition, University of Aberdeen to explore. Credit: University of AberdeenThousands of patients

Updated on:March 24,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on: May 23,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on:May 23,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on: June 15,2024

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Updated on:June 15,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on: September 07,2024

Blocking the longevity gene S6K1 extends lifespan in mice by reducing inflammation

by Medical Research Council (MRC) Laboratory of Medical SciencesS6K1 deletion attenuates age-related liver pathology.a, Experimental scheme.S6K1WT and KO mice were aged for 600 d to

Updated on:September 07,2024

Low back pain? Don't blame the weather

by WileyCloud in Nepali sky. Credit: WikipediaAustralian researchers reveal that sudden, acute episodes of low back pain are not linked to weather conditions such as temperature, humidity, air pr

Updated on: March 24,2024

Low back pain? Don't blame the weather

by WileyCloud in Nepali sky. Credit: WikipediaAustralian researchers reveal that sudden, acute episodes of low back pain are not linked to weather conditions such as temperature, humidity, air pr

Updated on:March 24,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on: June 15,2024

Lupus, rheumatoid arthritis tied to higher risk for adverse obstetric, birth outcomes

by Lori SolomonWomen with rheumatoid arthritis (RA) or systemic lupus erythematosus (SLE) and their infants experience higher rates of adverse obstetric and birth outcomes, according to a study publis

Updated on:June 15,2024

Mast cell levels may explain sex differences in osteoarthritis pain

by Hospital for Special SurgeryCredit: Pixabay/CC0 Public DomainInvestigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have signific

Updated on: April 17,2024

Mast cell levels may explain sex differences in osteoarthritis pain

by Hospital for Special SurgeryCredit: Pixabay/CC0 Public DomainInvestigators at Hospital for Special Surgery (HSS) have discovered that at the time of total knee replacement, women have signific

Updated on:April 17,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on: April 17,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on:April 17,2024