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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
Latest Articles
A better test for the tumor-targeting of CAR-T therapies

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r
Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10

Novel checkpoint molecule of natural killer cell anti-tumor immunity revealed

by Li Yuan,Chinese Academy of SciencesFig. 1. TIPE2 expression correlates with NK cell maturation in both mice and humans.(A) TIPE2 expression of purified splenic NK cells from 2-, 4-, 6-, or 10
Immune receptor provides protective immunity against Group A Streptococcus

Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t

Immune receptor provides protective immunity against Group A Streptococcus

by Osaka UniversityFig. 1: The mechanism by which group A Streptococcus (GAS) evades the immune system. The immune receptor Mincle recognizes MGDG, an immunoactivating lipid present on GAS, and t
Air pollution linked to having a peanut allergy during childhood

Air pollution linked to having a peanut allergy during childhood

byMurdoch Children's Research InstituteCredit: Pixabay/CC0 Public DomainExposure to higher levels of air pollution as a baby is linked to having a peanut allergy throughout childhood, accord

Air pollution linked to having a peanut allergy during childhood

byMurdoch Children's Research InstituteCredit: Pixabay/CC0 Public DomainExposure to higher levels of air pollution as a baby is linked to having a peanut allergy throughout childhood, accord
Survival improving after hip and knee replacement

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu

Survival improving after hip and knee replacement

(HealthDay)—Short-term survival after elective total hip (THR) and total knee replacement (TKR) has greatly improved since the early 1990s, even though comorbidities have increased, according to a stu
Anti-cancer virus fits tumor receptor like a 'key in a lock'

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are

Anti-cancer virus fits tumor receptor like a 'key in a lock'

by Okinawa Institute of Science and TechnologyA cryo-EM map of the receptor decorated capsid in which a single protomer was replaced with the atomic model. Seneca Valley Virus capsid proteins are
Motion analysis to detect arthrosis

Motion analysis to detect arthrosis

by Karlsruhe Institute of TechnologyMotion Analysis to Detect ArthrosisArthrosis is excessive wear of joints beyond the usual age-related degeneration. For this reason, about 150,000 German

Motion analysis to detect arthrosis

by Karlsruhe Institute of TechnologyMotion Analysis to Detect ArthrosisArthrosis is excessive wear of joints beyond the usual age-related degeneration. For this reason, about 150,000 German
How IL-6 allows the immune response to develop for a key cell, the T follicular helper

How IL-6 allows the immune response to develop for a key cell, the T follicular helper

by Jeff Hansen,University of Alabama at BirminghamAndre Ballesteros-Tato. Credit: UABThe body's immune response fights against infectious disease, and it safeguards against future infections

How IL-6 allows the immune response to develop for a key cell, the T follicular helper

by Jeff Hansen,University of Alabama at BirminghamAndre Ballesteros-Tato. Credit: UABThe body's immune response fights against infectious disease, and it safeguards against future infections
T cell response not critical for immune memory to SARS-CoV-2 or recovery from COVID-19

T cell response not critical for immune memory to SARS-CoV-2 or recovery from COVID-19

by American Society for MicrobiologyTransmission electron micrograph of SARS-CoV-2 virus particles isolated from a patient. Credit: NIAIDNew research conducted in monkeys reveals that T cells are

T cell response not critical for immune memory to SARS-CoV-2 or recovery from COVID-19

by American Society for MicrobiologyTransmission electron micrograph of SARS-CoV-2 virus particles isolated from a patient. Credit: NIAIDNew research conducted in monkeys reveals that T cells are
Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator
Early knee arthritis symptoms first felt when using stairs

Early knee arthritis symptoms first felt when using stairs

by University of LeedsPeople who suffer from knee pain when using the stairs may be experiencing the early symptoms of osteoarthritis, according to a new University of Leeds study.The research, p

Early knee arthritis symptoms first felt when using stairs

by University of LeedsPeople who suffer from knee pain when using the stairs may be experiencing the early symptoms of osteoarthritis, according to a new University of Leeds study.The research, p
Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f

Study finds holding methotrexate for one week after flu vaccine may be as effective as a two-week hold

by American College of RheumatologyStudy design and vaccine response at 4 and 16 weeks. (A) Study design. (B) The percentage of patients achieving a satisfactory vaccine response, defined as ≥4-f