CAR-T therapy modifications provide new promise for cancer immunotherapies

by King's College LondonCredit: CC0 Public DomainNew research led by Dr. John Maher, from the School of Cancer & Pharmaceutical Sciences, working for Leucid Bio and with biotech company L

Updated on: April 09,2024

CAR-T therapy modifications provide new promise for cancer immunotherapies

by King's College LondonCredit: CC0 Public DomainNew research led by Dr. John Maher, from the School of Cancer & Pharmaceutical Sciences, working for Leucid Bio and with biotech company L

Updated on:April 09,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on: April 24,2024

A better test for the tumor-targeting of CAR-T therapies

by Ludwig Institute for Cancer ResearchCredit: CC0 Public DomainLudwig Cancer Research scientists have developed a method to significantly improve the preclinical evaluation of chimeric antigen-r

Updated on:April 24,2024

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on: March 24,2024

The case of the missing monocyte: Scientists investigate gene that appears to protect against rheumatoid arthritis

by University of North Carolina at Chapel Hill School of MedicineThe hands of a person with arthritis. Image source: NIH.(Medical Xpress) -- An estimated 1.3 million people in the United States s

Updated on:March 24,2024

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on: May 08,2024

Method for delivering immune system-stimulating drugs may enhance cancer immunotherapy

by Anne Trafton,Massachusetts Institute of TechnologyThis image depicts a tumor right after treatment with alum-bound IL12. The pink dye shows IL-12, and the yellow shows alum. Credit: Massachus

Updated on:May 08,2024

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on: April 13,2024

A COVID-19 biomarker: Low blood levels of sphingosine predict symptomatic infections

by Medical University of South CarolinaImage of the ultrastructural morphology exhibited by the 2019 Novel Coronavirus (2019-nCoV). Credit: CDCResearchers remain perplexed as to why some patients

Updated on:April 13,2024

Brain activity linked to TNF inhibitor response in RA

Patients with rheumatoid arthritis who respond to tumor necrosis factor inhibitors show changes in activity in pain-related areas of the brain before clinical signs of improvement are observed, accord

Updated on: April 08,2024

Brain activity linked to TNF inhibitor response in RA

Patients with rheumatoid arthritis who respond to tumor necrosis factor inhibitors show changes in activity in pain-related areas of the brain before clinical signs of improvement are observed, accord

Updated on:April 08,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on: May 08,2024

TAp63: A new protein drug target for rheumatoid arthritis

by Chiba UniversityGraphical abstract. Credit:JCI Insight(2023). DOI: 10.1172/jci.insight.164778Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The

Updated on:May 08,2024

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on: May 07,2024

A key gene modifies regulatory T cells to fine-tune the immune response

by Salk InstituteA histology image showing inflammation in colon epithelium. Weakening of regulatory T cell function induces infiltration of immune cells (small blue dots) into colon epithelium (

Updated on:May 07,2024

Scientists discover how to improve vaccine response to potentially deadly bacterium

byTrinity College DublinScanning electromicrograph of Staphylococcus aureus bacteria. Credit: NIAIDResearchers from Trinity College Dublin have taken a leap forward in understanding how we might

Updated on: July 09,2024

Scientists discover how to improve vaccine response to potentially deadly bacterium

byTrinity College DublinScanning electromicrograph of Staphylococcus aureus bacteria. Credit: NIAIDResearchers from Trinity College Dublin have taken a leap forward in understanding how we might

Updated on:July 09,2024

Investigators discover unique immune cells in patients with checkpoint inhibitor-induced arthritis

by Hospital for Special SurgeryCredit: CC0 Public DomainSince doctors began treating cancer patients with immunotherapy drugs called checkpoint inhibitors nearly a decade ago, they have observed

Updated on: June 17,2024

Investigators discover unique immune cells in patients with checkpoint inhibitor-induced arthritis

by Hospital for Special SurgeryCredit: CC0 Public DomainSince doctors began treating cancer patients with immunotherapy drugs called checkpoint inhibitors nearly a decade ago, they have observed

Updated on:June 17,2024

Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b

Updated on: July 09,2024

Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b

Updated on:July 09,2024

Higher incidence of edema with bacteriuria in C1-INH-HAE

(HealthDay)—For patients with hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE), those with bacteriuria have a higher number of edematous attacks, according to a study published online

Updated on: April 08,2024

Higher incidence of edema with bacteriuria in C1-INH-HAE

(HealthDay)—For patients with hereditary angioedema due to C1-inhibitor deficiency (C1-INH-HAE), those with bacteriuria have a higher number of edematous attacks, according to a study published online

Updated on:April 08,2024