m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

Oral contraceptives may impact aspects of arthritis in women

by WileyThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterNew research indicates that use of oral contraceptives may provide benefits for women with inflammato

Updated on: April 17,2024

Oral contraceptives may impact aspects of arthritis in women

by WileyThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterNew research indicates that use of oral contraceptives may provide benefits for women with inflammato

Updated on:April 17,2024

Early-life exposure to famine linked to increased odds of RA

(HealthDay)—Individuals exposed to famine in utero or in early childhood have an increased likelihood of developing rheumatoid arthritis (RA) in adulthood, according to a study published in the April

Updated on: March 28,2024

Early-life exposure to famine linked to increased odds of RA

(HealthDay)—Individuals exposed to famine in utero or in early childhood have an increased likelihood of developing rheumatoid arthritis (RA) in adulthood, according to a study published in the April

Updated on:March 28,2024

Study finds COVID-19 vaccine not associated with severe disease flare in patients with rheumatic diseases

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that the

Updated on: June 17,2024

Study finds COVID-19 vaccine not associated with severe disease flare in patients with rheumatic diseases

by American College of RheumatologyCredit: Unsplash/CC0 Public DomainNew research presented this week at ACR Convergence, the American College of Rheumatology's annual meeting, shows that the

Updated on:June 17,2024

Researchers discover skin biomarkers in infants that predict early development of food allergies

by National Jewish HealthGraphical abstract. Credit:Journal of Allergy and Clinical Immunology(2024). DOI: 10.1016/j.jaci.2024.02.014Food allergies occur often in childhood and can be

Updated on: March 30,2024

Researchers discover skin biomarkers in infants that predict early development of food allergies

by National Jewish HealthGraphical abstract. Credit:Journal of Allergy and Clinical Immunology(2024). DOI: 10.1016/j.jaci.2024.02.014Food allergies occur often in childhood and can be

Updated on:March 30,2024

Protein eIF4A emerges as a potential Achilles' heel for triple-negative breast cancer

by Baylor College of MedicineGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI172503Improving treatments for triple-negative breast cancer (TNBC), a

Updated on: April 15,2024

Protein eIF4A emerges as a potential Achilles' heel for triple-negative breast cancer

by Baylor College of MedicineGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI172503Improving treatments for triple-negative breast cancer (TNBC), a

Updated on:April 15,2024

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever

Updated on: May 26,2024

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever

Updated on:May 26,2024

Yearly treatment could slow osteoarthritis

by Monash UniversityCredit: ThinkStock(Medical Xpress)—Researchers are trialling a once-a-year treatment to slow osteoarthritis.Led by Monash University Professor Flavia Cicuttini, the rese

Updated on: April 17,2024

Yearly treatment could slow osteoarthritis

by Monash UniversityCredit: ThinkStock(Medical Xpress)—Researchers are trialling a once-a-year treatment to slow osteoarthritis.Led by Monash University Professor Flavia Cicuttini, the rese

Updated on:April 17,2024

Discovery may explain why more females than males get knee osteoarthritis

by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainFemale astronauts could avoid knee injuries during space flight—and better tests, prevention and treatments could be d

Updated on: March 28,2024

Discovery may explain why more females than males get knee osteoarthritis

by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainFemale astronauts could avoid knee injuries during space flight—and better tests, prevention and treatments could be d

Updated on:March 28,2024

Women with rheumatoid arthritis more likely to achieve remission if they take sex hormones, finds research

by University of South AustraliaGraphical abstract. Credit:Rheumatology(2022). DOI: 10.1093/rheumatology/keac357A large study of women with rheumatoid arthritis has found that those t

Updated on: June 01,2024

Women with rheumatoid arthritis more likely to achieve remission if they take sex hormones, finds research

by University of South AustraliaGraphical abstract. Credit:Rheumatology(2022). DOI: 10.1093/rheumatology/keac357A large study of women with rheumatoid arthritis has found that those t

Updated on:June 01,2024

Researchers discover key metabolic process responsible for rapid immune responses

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct i

Updated on: March 19,2024

Researchers discover key metabolic process responsible for rapid immune responses

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct i

Updated on:March 19,2024

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to

Updated on: April 08,2024

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to

Updated on:April 08,2024