178

Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
Latest Articles
Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P

Study finds primary cilia restrict autoinflammation by mediating PD-L1 expression

by Science China PressLoss of primary cilia results in the downregulation of PD-L1 expression, which contributes to unrestrained local T cell proliferation and activation. Credit: Science China P
FDA approves first interchangeable biosimilar for inflammatory diseases

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),

FDA approves first interchangeable biosimilar for inflammatory diseases

(HealthDay)—The first interchangeable biosimilar product to Humira (adalimumab) was approved by the U.S. Food and Drug Administration on Oct. 15, the agency announced Monday.Cyltezo (adalimumab-adbm),
OX40-positive follicular helper T cells control rheumatoid arthritis

OX40-positive follicular helper T cells control rheumatoid arthritis

by University of TsukubaCredit: CC0 Public DomainRheumatoid arthritis is a progressive autoimmune disease most frequently characterized by pain, swelling, and stiffness in joints. Increased numbe

OX40-positive follicular helper T cells control rheumatoid arthritis

by University of TsukubaCredit: CC0 Public DomainRheumatoid arthritis is a progressive autoimmune disease most frequently characterized by pain, swelling, and stiffness in joints. Increased numbe
New pathway in immune defense discovered: Interaction of monocytes and platelets decoded

New pathway in immune defense discovered: Interaction of monocytes and platelets decoded

by Inka Väth,University Hospital Bonn(from left) Dr. Ibrahim Hawwari, Prof. Bernardo Franklin and Lukas Roßnagel discover new intercellular communication mechanism in which blood platelets, so-c

New pathway in immune defense discovered: Interaction of monocytes and platelets decoded

by Inka Väth,University Hospital Bonn(from left) Dr. Ibrahim Hawwari, Prof. Bernardo Franklin and Lukas Roßnagel discover new intercellular communication mechanism in which blood platelets, so-c
Scientists create first mouse model with complete, functional human immune system

Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b

Scientists create first mouse model with complete, functional human immune system

byUniversity of Texas Health Science Center at San AntonioLeft, malar rash in a (huNSGW41-derived) Lupus THX mouse (three weeks after pristane injection). Middle, serum antinuclear IgGs (scale b
Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator

Suppressing graft-versus-host disease using immunosuppressive iPS cell-derived regulatory T cells

by Kyoto UniversityGraphical abstract. Credit:Cell Stem Cell(2024). DOI: 10.1016/j.stem.2024.05.004A recent study by a team led by Professor Shin Kaneko successfully induced regulator
Abatacept therapy offers promising results for treating juvenile dermatomyositis

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a

Abatacept therapy offers promising results for treating juvenile dermatomyositis

by George Washington UniversityScreening, Trial Entry and Outcome. Credit:Arthritis & Rheumatology(2023). DOI: 10.1002/art.42450Juvenile dermatomyositis, a rare but often severe a
Patented technology uses curcumin for potent inhibitory effects on the development of food allergy

Patented technology uses curcumin for potent inhibitory effects on the development of food allergy

by Anna Zarra Aldrich,University of ConnecticutClinton Mathias in his UConn lab. Credit: Jason Sheldon / UConnClinton Mathias, associate professor of nutritional sciences in the College of Agric

Patented technology uses curcumin for potent inhibitory effects on the development of food allergy

by Anna Zarra Aldrich,University of ConnecticutClinton Mathias in his UConn lab. Credit: Jason Sheldon / UConnClinton Mathias, associate professor of nutritional sciences in the College of Agric
Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo

Anaphylaxis treatment remains confusing for patients, caregivers and emergency personnel, research finds

byAmerican College of Allergy, Asthma, and ImmunologyCredit: Unsplash/CC0 Public DomainAnaphylaxis can come on suddenly and without warning, and because its symptoms can be fatal, it is scary fo
Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis

Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis

byUniversity of TsukubaGraphical abstract. Credit:Clinical Immunology(2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in reg

Uncovering the cause of regulatory T cell dysfunction in elderly-onset rheumatoid arthritis

byUniversity of TsukubaGraphical abstract. Credit:Clinical Immunology(2024). DOI: 10.1016/j.clim.2024.110337Researchers at Tsukuba University have discovered that the increase in reg
Risk score predicts disease progression in patients with rheumatoid arthritis

Risk score predicts disease progression in patients with rheumatoid arthritis

by WileyCredit: Unsplash/CC0 Public DomainScientists have created a risk score based on thousands of genetic variants to determine the prognosis of individual patients with rheumatoid arthritis.I

Risk score predicts disease progression in patients with rheumatoid arthritis

by WileyCredit: Unsplash/CC0 Public DomainScientists have created a risk score based on thousands of genetic variants to determine the prognosis of individual patients with rheumatoid arthritis.I
Researchers uncover new cell types involved in osteoarthritis

Researchers uncover new cell types involved in osteoarthritis

by Valerie Goodwin,University of MichiganCredit: Unsplash/CC0 Public DomainA Michigan Medicine study has identified a new potential target for treating osteoarthritis—a debilitating joint diseas

Researchers uncover new cell types involved in osteoarthritis

by Valerie Goodwin,University of MichiganCredit: Unsplash/CC0 Public DomainA Michigan Medicine study has identified a new potential target for treating osteoarthritis—a debilitating joint diseas