A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on: May 07,2024

A new toolkit to engineer safe and efficient therapeutic cells

by Stacie Dodgson and Françoise Chanut,Gladstone InstitutesGraphical abstract. Credit:Cell(2022). DOI: 10.1016/j.cell.2022.03.023Therapies based on engineered immune cells have recen

Updated on:May 07,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on: April 16,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on:April 16,2024

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on: April 20,2024

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on:April 20,2024

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on: March 27,2024

Research unveils metabolic strategies to enhance CAR-T cell therapy

by Cactus CommunicationsChimeric antigen receptor T (CAR-T) cell therapy effectively treats hematological tumors but struggles due to metabolic challenges in the tumor microenvironment. Tumor cells di

Updated on:March 27,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on: May 23,2024

Warfarin use significantly increases risk of knee and hip replacement in people with OA

by American College of RheumatologyCredit: CC0 Public DomainNew research presented at ACR Convergence, the American College of Rheumatology's annual meeting, shows that use of warfarin, a vit

Updated on:May 23,2024

Novel noninvasive molecular imaging for monitoring rheumatoid arthritis

by Society of Nuclear Medicine and Molecular ImagingComparison of Tc-99m tilmanocept radiopharmaceutical uptake on planar imaging in subjects with active RA (A: 200 μg tilmanocept / 10 mCi Tc-99m; B-C

Updated on: May 08,2024

Novel noninvasive molecular imaging for monitoring rheumatoid arthritis

by Society of Nuclear Medicine and Molecular ImagingComparison of Tc-99m tilmanocept radiopharmaceutical uptake on planar imaging in subjects with active RA (A: 200 μg tilmanocept / 10 mCi Tc-99m; B-C

Updated on:May 08,2024

Rheumatoid arthritis tied to heavy economic and human burdens

by Lori SolomonRheumatoid arthritis (RA) is associated with higher health care expenditures and suboptimal quality of life in U.S. adults, according to a studypublishedonline Aug. 6 in&nbs

Updated on: October 09,2024

Rheumatoid arthritis tied to heavy economic and human burdens

by Lori SolomonRheumatoid arthritis (RA) is associated with higher health care expenditures and suboptimal quality of life in U.S. adults, according to a studypublishedonline Aug. 6 in&nbs

Updated on:October 09,2024

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to

Updated on: April 08,2024

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to

Updated on:April 08,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on: June 17,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on:June 17,2024

Scientists discover new mechanism controlling T-cells in inflammation

by Melissa Rohman,Northwestern UniversityGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.08.008Northwestern Medicine scientists have discovered a new mechanism

Updated on: October 10,2024

Scientists discover new mechanism controlling T-cells in inflammation

by Melissa Rohman,Northwestern UniversityGraphical abstract. Credit:Immunity(2024). DOI: 10.1016/j.immuni.2024.08.008Northwestern Medicine scientists have discovered a new mechanism

Updated on:October 10,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on: March 24,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on:March 24,2024

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on: May 05,2024

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on:May 05,2024