How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on: May 05,2024

How one patient's rare mutation helped solve a mycobacterial mystery

by Katherine Fenz,Rockefeller UniversityGraphical Abstract. Credit:Cell(2020). DOI: 10.1016/j.cell.2020.10.046Just because you are exposed to a pathogen does not mean you will become

Updated on:May 05,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

A protein's surprising role offers clues to limit graft-vs.-host disease

by Nicole Fawcett,University of MichiganFrom left, Hideaki Fujiwara, M.D., Ph.D.; Grace Chen, M.D., Ph.D.; and Pavan Reddy, M.D. Credit: University of Michigan Rogel Cancer CenterA protein that

Updated on: May 07,2024

A protein's surprising role offers clues to limit graft-vs.-host disease

by Nicole Fawcett,University of MichiganFrom left, Hideaki Fujiwara, M.D., Ph.D.; Grace Chen, M.D., Ph.D.; and Pavan Reddy, M.D. Credit: University of Michigan Rogel Cancer CenterA protein that

Updated on:May 07,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on: March 24,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on:March 24,2024

Researchers identify genes at play in people with osteoarthritis

by Anne Sliper Midling,Norwegian University of Science and TechnologyCredit: CC0 Public DomainOsteoarthritis is the leading cause of pain and disability worldwide.There is no cure, onlypai

Updated on: April 20,2024

Researchers identify genes at play in people with osteoarthritis

by Anne Sliper Midling,Norwegian University of Science and TechnologyCredit: CC0 Public DomainOsteoarthritis is the leading cause of pain and disability worldwide.There is no cure, onlypai

Updated on:April 20,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on: April 16,2024

HSPC-derived CAR T-cells capable of lasting engraftment

(HealthDay)—Hematopoietic stem/progenitor cell (HSPC)-derived chimeric antigen receptor (CAR) T-cells are capable of long-term engraftment in a model of HIV/AIDS, according to a study published online

Updated on:April 16,2024

COVID: On the lookout for new antibodies

by Friedrich–Alexander University Erlangen–NurnbergCredit: Pixabay/CC0 Public DomainA team of researchers at FAU and Universitätsklinikum Erlangen has gained new insights into the maturation of S

Updated on: April 13,2024

COVID: On the lookout for new antibodies

by Friedrich–Alexander University Erlangen–NurnbergCredit: Pixabay/CC0 Public DomainA team of researchers at FAU and Universitätsklinikum Erlangen has gained new insights into the maturation of S

Updated on:April 13,2024

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on: April 20,2024

OCTAVE study reveals vaccine responses in patients with impaired immune systems

by University of GlasgowCredit: Pixabay/CC0 Public DomainThe OCTAVE study—a multi-center, UK-wide trial, led by the University of Glasgow and co-ordinated by the University of Birmingham's Ca

Updated on:April 20,2024

Rheumatoid arthritis tied to heavy economic and human burdens

by Lori SolomonRheumatoid arthritis (RA) is associated with higher health care expenditures and suboptimal quality of life in U.S. adults, according to a studypublishedonline Aug. 6 in&nbs

Updated on: October 09,2024

Rheumatoid arthritis tied to heavy economic and human burdens

by Lori SolomonRheumatoid arthritis (RA) is associated with higher health care expenditures and suboptimal quality of life in U.S. adults, according to a studypublishedonline Aug. 6 in&nbs

Updated on:October 09,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on: June 17,2024

Is rheumatoid arthritis two different diseases?

by Public Library of ScienceCredit: CC0 Public DomainWhile disease activity improves over time for most rheumatoid arthritis (RA) patients, long-term outcomes only improve in RA patients with aut

Updated on:June 17,2024

Serum biomarkers can differentiate psoriatic arthritis, rheumatoid arthritis

(HealthDay)—A serum protein biomarker panel can differentiate patients with early inflammatory arthritis with psoriatic arthritis (PsA) from those with rheumatoid arthritis (RA), according to a study

Updated on: June 06,2024

Serum biomarkers can differentiate psoriatic arthritis, rheumatoid arthritis

(HealthDay)—A serum protein biomarker panel can differentiate patients with early inflammatory arthritis with psoriatic arthritis (PsA) from those with rheumatoid arthritis (RA), according to a study

Updated on:June 06,2024

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to

Updated on: April 08,2024

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to

Updated on:April 08,2024