Protein eIF4A emerges as a potential Achilles' heel for triple-negative breast cancer

by Baylor College of MedicineGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI172503Improving treatments for triple-negative breast cancer (TNBC), a

Updated on: April 15,2024

Protein eIF4A emerges as a potential Achilles' heel for triple-negative breast cancer

by Baylor College of MedicineGraphical abstract. Credit:Journal of Clinical Investigation(2023). DOI: 10.1172/JCI172503Improving treatments for triple-negative breast cancer (TNBC), a

Updated on:April 15,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on: April 17,2024

Chromosomal loop signatures could identify poor drug response in arthritis

by University of GlasgowCredit: University of GlasgowChromosomal loop signatures found in blood samples obtained in early rheumatoid arthritis could identify patients that will not respond adequa

Updated on:April 17,2024

COVID infection may boost antibodies for up to 20 months

If you've already had COVID-19, your natural antibodies may last as long as 20 months, a new study suggests.While this is reassuring, experts are quick to caution that the new findings don't n

Updated on: April 13,2024

COVID infection may boost antibodies for up to 20 months

If you've already had COVID-19, your natural antibodies may last as long as 20 months, a new study suggests.While this is reassuring, experts are quick to caution that the new findings don't n

Updated on:April 13,2024

Discovery may explain why more females than males get knee osteoarthritis

by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainFemale astronauts could avoid knee injuries during space flight—and better tests, prevention and treatments could be d

Updated on: March 28,2024

Discovery may explain why more females than males get knee osteoarthritis

by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainFemale astronauts could avoid knee injuries during space flight—and better tests, prevention and treatments could be d

Updated on:March 28,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on: April 16,2024

m6A mRNA modification potentiates Th17 functions to inflame autoimmunity

by Science China PressLoss of METTL3 in Th17 cells facilitated SOCS family RNA stability, inhibited IL-6/STAT3 mediated IL-17A and CCR5 expression, which in turn impeding Th17 cells differentiati

Updated on:April 16,2024

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever

Updated on: May 26,2024

Gene variant exacerbates inflammatory arthritis in mice

by University of Utah Health SciencesA swollen ankle joint with severe inflammatory arthritis. A build up of glycosaminoglycans (GAGs), long carbohydrate chains, is thought to contribute to sever

Updated on:May 26,2024

Researchers discover key metabolic process responsible for rapid immune responses

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct i

Updated on: March 19,2024

Researchers discover key metabolic process responsible for rapid immune responses

by Children's Hospital of PhiladelphiaCredit: Pixabay/CC0 Public DomainResearchers from Children's Hospital of Philadelphia (CHOP) identified a key metabolite in cells that helps direct i

Updated on:March 19,2024

Oral contraceptives may impact aspects of arthritis in women

by WileyThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterNew research indicates that use of oral contraceptives may provide benefits for women with inflammato

Updated on: April 17,2024

Oral contraceptives may impact aspects of arthritis in women

by WileyThis is a hand afflicted by rheumatoid arthritis. Credit: The University of ManchesterNew research indicates that use of oral contraceptives may provide benefits for women with inflammato

Updated on:April 17,2024

Arthritis sufferers excluded from everyday life

by Fran Strachan,University of New South WalesCredit: ThinkstockArthritis is the second leading cause of disability in Australia with many sufferers so severely disabled they cannot engage in ba

Updated on: March 24,2024

Arthritis sufferers excluded from everyday life

by Fran Strachan,University of New South WalesCredit: ThinkstockArthritis is the second leading cause of disability in Australia with many sufferers so severely disabled they cannot engage in ba

Updated on:March 24,2024

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to

Updated on: April 08,2024

Allergies may plague renters more than homeowners

Those who rent less likely to take steps to reduce indoor allergy triggers, study finds .(HealthDay) -- People with common indoor allergies who rent their home are much less likely than homeowners to

Updated on:April 08,2024

Researchers identify new target for rheumatoid arthritis

by Hospital for Special SurgeryCo-senior author and Program Director Carl Blobel, M.D., Ph.D., works with collaborator Lionel Ivashkiv, M.D., in the Arthritis and Tissue Degeneration Program lab

Updated on: March 24,2024

Researchers identify new target for rheumatoid arthritis

by Hospital for Special SurgeryCo-senior author and Program Director Carl Blobel, M.D., Ph.D., works with collaborator Lionel Ivashkiv, M.D., in the Arthritis and Tissue Degeneration Program lab

Updated on:March 24,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on: March 24,2024

Arthritis, other chronic disease takes toll on work force

(HealthDay)—Among adults with one or more chronic conditions, those with arthritis appear much more likely than those without arthritis to have work disability, according to research published in the

Updated on:March 24,2024