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Immunology & Rheumatology
Focuses on rheumatic and immune diseases.
Sub Categories on Immunology & Rheumatology
Latest Articles
Preclinical study of COVID-19 vaccine candidate shows potent T-cell responses

Preclinical study of COVID-19 vaccine candidate shows potent T-cell responses

by University of Alabama at BirminghamCredit: University of Alabama at BirminghamPreclinical studies of a COVID-19 vaccine candidate at the University of Alabama at Birmingham show positive resul

Preclinical study of COVID-19 vaccine candidate shows potent T-cell responses

by University of Alabama at BirminghamCredit: University of Alabama at BirminghamPreclinical studies of a COVID-19 vaccine candidate at the University of Alabama at Birmingham show positive resul
CAR T-cell immunotherapy rids woman of tough-to-treat lupus

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already

CAR T-cell immunotherapy rids woman of tough-to-treat lupus

by Amy Norton(HealthDay)—In a first, researchers have used genetically tweaked immune system cells to send a woman's severe lupus into remission.The treatment—called CAR T-cell therapy—is already
CAR T cell therapies may lead to reactivation of childhood viral infections

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca

CAR T cell therapies may lead to reactivation of childhood viral infections

by Justin Jackson , Medical XpressPetabase-scale analysis of viral nucleic acids reveals that HHV-6 is reactivated in human T cells. a, Schematic of life cycles of endogenous human viruses. Viruses ca
CAR T cell therapy could reach beyond cancer

CAR T cell therapy could reach beyond cancer

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainEngineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can

CAR T cell therapy could reach beyond cancer

by Perelman School of Medicine at the University of PennsylvaniaCredit: CC0 Public DomainEngineered immune cells, known as CAR T cells, have shown the world what personalized immunotherapies can
Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex

Three-dimensional label-free morphology of CD8+ T cells as a sepsis biomarker

by Chinese Academy of Sciencesa, Schematic overview of the study workflow. Blood was sampled three times in the sepsis recovery cohort and once in the healthy control cohort. CD8+ T cells were ex
Post-COVID-19 conditions alter a person's immune response

Post-COVID-19 conditions alter a person's immune response

by Cedars-Sinai Medical CenterCredit: Unsplash/CC0 Public DomainA new study by investigators from the Smidt Heart Institute at Cedars-Sinai suggests long COVID-19 might be caused by a dysfunction

Post-COVID-19 conditions alter a person's immune response

by Cedars-Sinai Medical CenterCredit: Unsplash/CC0 Public DomainA new study by investigators from the Smidt Heart Institute at Cedars-Sinai suggests long COVID-19 might be caused by a dysfunction
Promising target for CAR T cells helps cancer trick the immune system

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi

Promising target for CAR T cells helps cancer trick the immune system

by St. Jude Children's Research HospitalGraphical abstract. Credit:Cell Reports Medicine(2023). DOI: 10.1016/j.xcrm.2023.101297Findings from St. Jude Children's Research Hospi
COVID-19, MIS-C and Kawasaki disease share same immune response

COVID-19, MIS-C and Kawasaki disease share same immune response

by University of California - San DiegoUC San Diego researchers summarize the similarities and differences between COVID-19, MIS-C and Kawasaki disease, three conditions unified by the same immun

COVID-19, MIS-C and Kawasaki disease share same immune response

by University of California - San DiegoUC San Diego researchers summarize the similarities and differences between COVID-19, MIS-C and Kawasaki disease, three conditions unified by the same immun
CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l

CAR T cells suppress GI solid tumor cells, without toxicity to healthy tissue, in preclinical research

by University of PennsylvaniaCDH17 CARTs attack tumor but spare normal tissue. Credit: Penn MedicineChimeric antigen receptor (CAR) T cells can be remarkably effective in treating leukemias and l
Covert tactics used by bacteria to trick human immune system

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p

Covert tactics used by bacteria to trick human immune system

by McMaster UniversityBrian Coombes in his lab at McMaster University. Credit: McMaster UniversityMcMaster University researchers have found a new way bacteria evade the human immune system and p
Why COVID patients become critically ill

Why COVID patients become critically ill

by University of AmsterdamCredit: Unsplash/CC0 Public DomainResearchers at Amsterdam UMC have discovered why patients become seriously ill after being infected with the coronavirus. They identifi

Why COVID patients become critically ill

by University of AmsterdamCredit: Unsplash/CC0 Public DomainResearchers at Amsterdam UMC have discovered why patients become seriously ill after being infected with the coronavirus. They identifi
Risk of severe breakthrough COVID-19 infection is higher for people with HIV with moderately low CD4 cell counts

Risk of severe breakthrough COVID-19 infection is higher for people with HIV with moderately low CD4 cell counts

by Johns Hopkins University Bloomberg School of Public HealthGraphs show incidence of severe COVID-19 breakthrough illness by HIV status (A) (log-rank test P = .40), by CD4 cell count and HIV sta

Risk of severe breakthrough COVID-19 infection is higher for people with HIV with moderately low CD4 cell counts

by Johns Hopkins University Bloomberg School of Public HealthGraphs show incidence of severe COVID-19 breakthrough illness by HIV status (A) (log-rank test P = .40), by CD4 cell count and HIV sta