Research shows that being overweight hampers the body's immune response to SARS-CoV-2

byUniversity of QueenslandCredit: Unsplash/CC0 Public DomainUniversity of Queensland-led research shows being overweight can impair the body's antibody response to SARS-CoV-2 infection but n

Updated on: January 25,2024 17

Research shows that being overweight hampers the body's immune response to SARS-CoV-2

byUniversity of QueenslandCredit: Unsplash/CC0 Public DomainUniversity of Queensland-led research shows being overweight can impair the body's antibody response to SARS-CoV-2 infection but n

Updated on:January 25,2024 17

Finding the source of debilitating, body-wide muscular pain and weakness

byTokyo Medical and Dental UniversityPD-1+CD8+ T cells were activated rather than exhausted. PD-1+CD8+ T cells infiltrated muscle tissues. Affected muscles reacted to IFNγ, which could be produc

Updated on: January 25,2024 14

Finding the source of debilitating, body-wide muscular pain and weakness

byTokyo Medical and Dental UniversityPD-1+CD8+ T cells were activated rather than exhausted. PD-1+CD8+ T cells infiltrated muscle tissues. Affected muscles reacted to IFNγ, which could be produc

Updated on:January 25,2024 14

Fungus-fighting protein could help overcome severe autoimmune disease and cancer

byAustralian National UniversityA 3D printed stencil of the DECTIN-1 protein's structure. Credit: Tracey Nearmy/ANUA protein in the immune system programmed to protect the body from fungal i

Updated on: January 25,2024 24

Fungus-fighting protein could help overcome severe autoimmune disease and cancer

byAustralian National UniversityA 3D printed stencil of the DECTIN-1 protein's structure. Credit: Tracey Nearmy/ANUA protein in the immune system programmed to protect the body from fungal i

Updated on:January 25,2024 24

Novel study design could improve research on future pandemics

by Association for Diagnostic and Laboratory MedicineCredit: CC0 Public DomainA special report published inThe Journal of Applied Laboratory Medicinedescribes the design, operations, and m

Updated on: January 25,2024 21

Novel study design could improve research on future pandemics

by Association for Diagnostic and Laboratory MedicineCredit: CC0 Public DomainA special report published inThe Journal of Applied Laboratory Medicinedescribes the design, operations, and m

Updated on:January 25,2024 21

Real-world data show impact of immunotherapy in populations underrepresented in clinical trials

by National Comprehensive Cancer NetworkCredit: Pixabay/CC0 Public DomainNew research in the December 2023 issue ofJournal of the National Comprehensive Cancer Networkfinds that patients t

Updated on: January 25,2024 25

Real-world data show impact of immunotherapy in populations underrepresented in clinical trials

by National Comprehensive Cancer NetworkCredit: Pixabay/CC0 Public DomainNew research in the December 2023 issue ofJournal of the National Comprehensive Cancer Networkfinds that patients t

Updated on:January 25,2024 25

Updated guidelines issued for management of anaphylaxis

by Elana GotkineIn a practice parameter update published online Dec. 17 in theAnnals of Allergy, Asthma & Immunology, new guidelines are presented for the diagnosis and management of anaphyl

Updated on: January 25,2024 13

Updated guidelines issued for management of anaphylaxis

by Elana GotkineIn a practice parameter update published online Dec. 17 in theAnnals of Allergy, Asthma & Immunology, new guidelines are presented for the diagnosis and management of anaphyl

Updated on:January 25,2024 13

Systemic AL amyloidosis: Current approach and future direction

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new review paper was published inOncotarget, titled "Systemic AL amyloidosis: current approach and future direction."In this re

Updated on: January 10,2024 12

Systemic AL amyloidosis: Current approach and future direction

by Impact Journals LLCCredit: Pixabay/CC0 Public DomainA new review paper was published inOncotarget, titled "Systemic AL amyloidosis: current approach and future direction."In this re

Updated on:January 10,2024 12

Medical researchers tackle immune rejection of biomedical implants

byUniversity of ArizonaPathological FBR in humans is mediated by RAC2 mechanotransduction signaling, regardless of implant properties, and is associated with increased mechanical signaling. Cred

Updated on: January 07,2024 10

Medical researchers tackle immune rejection of biomedical implants

byUniversity of ArizonaPathological FBR in humans is mediated by RAC2 mechanotransduction signaling, regardless of implant properties, and is associated with increased mechanical signaling. Cred

Updated on:January 07,2024 10

Single-cell RNA-sequencing analysis reveals immune cell heterogeneity in five autoimmune diseases

by Compuscript LtdSingle-cell landscape of peripheral blood mononuclear cells (PBMCs) from healthy controls and patients with five autoimmune disease. UMAP illustration of the integrated scRNA-seq dat

Updated on: January 07,2024 9

Single-cell RNA-sequencing analysis reveals immune cell heterogeneity in five autoimmune diseases

by Compuscript LtdSingle-cell landscape of peripheral blood mononuclear cells (PBMCs) from healthy controls and patients with five autoimmune disease. UMAP illustration of the integrated scRNA-seq dat

Updated on:January 07,2024 9

3D genome architecture influences SCID-X1 gene therapy success

bySt. Jude Children's Research HospitalGenomic signatures of lentiviral VIS. (A) Circular projection of the human genome with integration sites from patients 1, 2, 3, and 6. Gene names near

Updated on: January 06,2024 18

3D genome architecture influences SCID-X1 gene therapy success

bySt. Jude Children's Research HospitalGenomic signatures of lentiviral VIS. (A) Circular projection of the human genome with integration sites from patients 1, 2, 3, and 6. Gene names near

Updated on:January 06,2024 18

Scientists devise new technique that can pinpoint causes, treatments of autoimmune diseases

by Alan Williams,University of PlymouthSECRE combined with a CRISPR screen identifies regulators of IFNγ secretion.a, Schematic of CRISPR screen workflow. PBMC, peripheral blood mononuclea

Updated on: January 04,2024 17

Scientists devise new technique that can pinpoint causes, treatments of autoimmune diseases

by Alan Williams,University of PlymouthSECRE combined with a CRISPR screen identifies regulators of IFNγ secretion.a, Schematic of CRISPR screen workflow. PBMC, peripheral blood mononuclea

Updated on:January 04,2024 17

B cell-deficient patients gain protective T cell immunity following SARS-CoV-2 vaccination and infection, study finds

by Ragon Institute of MGH, MIT and Harvard3D rendering of a B cell. Credit: Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/w

Updated on: December 30,2023 7

B cell-deficient patients gain protective T cell immunity following SARS-CoV-2 vaccination and infection, study finds

by Ragon Institute of MGH, MIT and Harvard3D rendering of a B cell. Credit: Blausen.com staff (2014). "Medical gallery of Blausen Medical 2014". WikiJournal of Medicine 1 (2). DOI:10.15347/w

Updated on:December 30,2023 7