The fate of drug discovery in academia: Why is it so difficult?

FEBRUARY 5, 2024by Impact Journals LLCA typical drug discovery and development strategy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28552A new editorial paper titled "The fate

Updated on: March 25,2024 3

The fate of drug discovery in academia: Why is it so difficult?

FEBRUARY 5, 2024by Impact Journals LLCA typical drug discovery and development strategy. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28552A new editorial paper titled "The fate

Updated on:March 25,2024 3

New drug halts growth of aggressive breast cancer in pre-clinical study

FEBRUARY 5, 2024by Jessica Stanley,University of AdelaideCDDD11-8 inhibits proliferation of patient-derived breast organoid models. Credit:Oncogene(2023). DOI: 10.1038/s41388-023-028

Updated on: March 25,2024 6

New drug halts growth of aggressive breast cancer in pre-clinical study

FEBRUARY 5, 2024by Jessica Stanley,University of AdelaideCDDD11-8 inhibits proliferation of patient-derived breast organoid models. Credit:Oncogene(2023). DOI: 10.1038/s41388-023-028

Updated on:March 25,2024 6

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

Updated on: March 25,2024 6

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

Updated on:March 25,2024 6

New recommendations make it easier for patients to give feedback on their health

FEBRUARY 29, 2024byUniversity of BirminghamCredit: CC0 Public DomainPatients providing feedback on their health during research or in clinical practice could now find it less onerous, thanks to

Updated on: March 25,2024 4

New recommendations make it easier for patients to give feedback on their health

FEBRUARY 29, 2024byUniversity of BirminghamCredit: CC0 Public DomainPatients providing feedback on their health during research or in clinical practice could now find it less onerous, thanks to

Updated on:March 25,2024 4

New findings suggest life span can be increased by making cells less efficient at producing energy

by Pennington Biomedical Research CenterChristopher Axelrod, Director, Integrated Physiology and Molecular Medicine Laboratory at Pennington Biomedical Research Center. Credit: PBRCA newstudy&nb

Updated on: March 25,2024 3

New findings suggest life span can be increased by making cells less efficient at producing energy

by Pennington Biomedical Research CenterChristopher Axelrod, Director, Integrated Physiology and Molecular Medicine Laboratory at Pennington Biomedical Research Center. Credit: PBRCA newstudy&nb

Updated on:March 25,2024 3

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell

Updated on: March 25,2024 16

New study shows a role for cholesterol in pain perception

FEBRUARY 27, 2024byUniversity of FloridaA cell membrane is illustrated to show the surface in red. Blue objects are proteins, including ion channels, which can send electrical impulses into cell

Updated on:March 25,2024 16

New trial highlights incremental progress towards a cure for HIV-1

FEBRUARY 13, 2024byUniversity of North Carolina School of MedicineLymphocyte with HIV cluster. Credit: Unsplash/CC0 Public DomainAntiretroviral therapies (ART) stop HIV replication in its tracks

Updated on: March 25,2024 11

New trial highlights incremental progress towards a cure for HIV-1

FEBRUARY 13, 2024byUniversity of North Carolina School of MedicineLymphocyte with HIV cluster. Credit: Unsplash/CC0 Public DomainAntiretroviral therapies (ART) stop HIV replication in its tracks

Updated on:March 25,2024 11

New methodological approach allows more precise summary of study results

JANUARY 24, 2024byInstitute for Quality and Efficiency in Health CareCredit: Pixabay/CC0 Public DomainBefore new drugs are launched on the market they are tested in clinical studies in which one

Updated on: March 25,2024 4

New methodological approach allows more precise summary of study results

JANUARY 24, 2024byInstitute for Quality and Efficiency in Health CareCredit: Pixabay/CC0 Public DomainBefore new drugs are launched on the market they are tested in clinical studies in which one

Updated on:March 25,2024 4

Developing standards for organ-on-a-chip research

FEBRUARY 22, 2024by Jennifer Lauren Lee,National Institute of Standards and TechnologyOrgan-on-a-chip devices use tiny structures called microfluidic channels to bring small, controlled amounts

Updated on: March 25,2024 8

Developing standards for organ-on-a-chip research

FEBRUARY 22, 2024by Jennifer Lauren Lee,National Institute of Standards and TechnologyOrgan-on-a-chip devices use tiny structures called microfluidic channels to bring small, controlled amounts

Updated on:March 25,2024 8

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Updated on: March 25,2024 5

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Updated on:March 25,2024 5

Investigating the ethical landscape of brain organoid research

FEBRUARY 28, 2024byKyoto UniversityCredit: Pixabay/CC0 Public DomainWith advances in neuroscience and the development of new technologies, new ethical considerations have emerged. This is partic

Updated on: March 25,2024 10

Investigating the ethical landscape of brain organoid research

FEBRUARY 28, 2024byKyoto UniversityCredit: Pixabay/CC0 Public DomainWith advances in neuroscience and the development of new technologies, new ethical considerations have emerged. This is partic

Updated on:March 25,2024 10

Human cells building 'molecular highways' captured for first time

FEBRUARY 1, 2024byCenter for Genomic Regulationγ-TuRC starting the nucleation process (left) vs. γ-TuRC closing (right). Once closed, thhe foundation is set and tubulins can be added to make the

Updated on: March 25,2024 8

Human cells building 'molecular highways' captured for first time

FEBRUARY 1, 2024byCenter for Genomic Regulationγ-TuRC starting the nucleation process (left) vs. γ-TuRC closing (right). Once closed, thhe foundation is set and tubulins can be added to make the

Updated on:March 25,2024 8