Novel pancreatic cancer organoids show promise for effective screening of anticancer drugs

byUniversity of TokyoGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113420Pancreatic ductal adenocarcinoma (PDAC), that arises from pancreatic epithelial c

Updated on: January 26,2024 13

Novel pancreatic cancer organoids show promise for effective screening of anticancer drugs

byUniversity of TokyoGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113420Pancreatic ductal adenocarcinoma (PDAC), that arises from pancreatic epithelial c

Updated on:January 26,2024 13

Study: Solid organ transplant patients benefit from COVID-19 treatment

byCedars-Sinai Medical CenterTix-Cil dosing and infections during the study period. The frequency and timing of Tix-Cil dosing and SARS-CoV-2 infections occurring in the study cohort is shown in

Updated on: January 26,2024 19

Study: Solid organ transplant patients benefit from COVID-19 treatment

byCedars-Sinai Medical CenterTix-Cil dosing and infections during the study period. The frequency and timing of Tix-Cil dosing and SARS-CoV-2 infections occurring in the study cohort is shown in

Updated on:January 26,2024 19

Treating tuberculosis when antibiotics no longer work

byUniversity of CologneCredit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2023.12.007Researchers have identified new antibiotic molecules that target Mycobacterium tuberculo

Updated on: January 26,2024 20

Treating tuberculosis when antibiotics no longer work

byUniversity of CologneCredit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2023.12.007Researchers have identified new antibiotic molecules that target Mycobacterium tuberculo

Updated on:January 26,2024 20

Medicare doesn't cover obesity drugs, but 76% of older adults think it should: Poll

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainThe vast majority of older adults—83%—think health insurers should cover medications that can help people with obesity manage their weigh

Updated on: January 26,2024 16

Medicare doesn't cover obesity drugs, but 76% of older adults think it should: Poll

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainThe vast majority of older adults—83%—think health insurers should cover medications that can help people with obesity manage their weigh

Updated on:January 26,2024 16

Drug found to extend survival in prostate cancer with genetic mutations

by Melissa Rohman,Northwestern University(A) rPFS for patients with a germline BRCA alteration, (B) rPFS for patients with a somatic BRCA alteration, (C) OS for patients with a germline BRCA alt

Updated on: January 26,2024 0

Drug found to extend survival in prostate cancer with genetic mutations

by Melissa Rohman,Northwestern University(A) rPFS for patients with a germline BRCA alteration, (B) rPFS for patients with a somatic BRCA alteration, (C) OS for patients with a germline BRCA alt

Updated on:January 26,2024 0

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor

Updated on: January 26,2024 18

Researchers race to develop Paxlovid replacement

by Andrew Smith,Rutgers UniversityX-ray crystal structure of the covalent inhibitor Jun11313 with SARS-CoV-2 PLproand structure-based design of biarylphenyl SARS-CoV-2 PLproinhibitor

Updated on:January 26,2024 18

Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

by Impact Journals LLCAGE enhances endothelial relaxation in aorta rings. (A) Representative traces under specified conditions. (B) Percentage of relaxation proportional to Ach concentration. (C) Maxi

Updated on: January 26,2024 14

Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

by Impact Journals LLCAGE enhances endothelial relaxation in aorta rings. (A) Representative traces under specified conditions. (B) Percentage of relaxation proportional to Ach concentration. (C) Maxi

Updated on:January 26,2024 14

Study finds moderately elevated fracture risk following use of sedative–hypnotics

byThe University of Hong KongCredit: Unsplash/CC0 Public DomainGlobal consumption data show that there is an increasing trend of sedative–hypnotic prescriptions, especially in more developed aff

Updated on: January 26,2024 20

Study finds moderately elevated fracture risk following use of sedative–hypnotics

byThe University of Hong KongCredit: Unsplash/CC0 Public DomainGlobal consumption data show that there is an increasing trend of sedative–hypnotic prescriptions, especially in more developed aff

Updated on:January 26,2024 20

Popular blood thinner associated with higher risk of bleeding complications

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhen diagnosed with a blood clot or atrial fibrillation, patients are often prescribed anticoagulants, or blood thinners, to prevent a fu

Updated on: January 26,2024 10

Popular blood thinner associated with higher risk of bleeding complications

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhen diagnosed with a blood clot or atrial fibrillation, patients are often prescribed anticoagulants, or blood thinners, to prevent a fu

Updated on:January 26,2024 10

Clinical trial highlights possible treatment for anemia in myelodysplastic neoplasms

by Anne Grimm,Leipzig UniversityCredit: Pixabay/CC0 Public DomainIn patients affected by myelodysplastic neoplasms, the body does not produce enough functional blood cells. Patients suffer from

Updated on: January 26,2024 19

Clinical trial highlights possible treatment for anemia in myelodysplastic neoplasms

by Anne Grimm,Leipzig UniversityCredit: Pixabay/CC0 Public DomainIn patients affected by myelodysplastic neoplasms, the body does not produce enough functional blood cells. Patients suffer from

Updated on:January 26,2024 19

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Updated on: January 26,2024 12

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Updated on:January 26,2024 12

Using next-gen CRISPR tool, scientists create unprecedented molecular map of human immune response

byGladstone InstitutesCarl Ward, PhD, a postdoctoral researcher in the Marson Lab at Gladstone Institutes, was co-first author of the landmark study in Nature, along with fellow co-first author

Updated on: January 26,2024 14

Using next-gen CRISPR tool, scientists create unprecedented molecular map of human immune response

byGladstone InstitutesCarl Ward, PhD, a postdoctoral researcher in the Marson Lab at Gladstone Institutes, was co-first author of the landmark study in Nature, along with fellow co-first author

Updated on:January 26,2024 14