Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity

Updated on: March 13,2024 11

Genetics may influence the body's response to low oxygen, study finds

byUniversity of PittsburghImmunofluorescent staining for the lncRNA fragment in a diseased pulmonary vessel from a patient with pulmonary arterial hypertension. Credit: Thomas BerteroUniversity

Updated on:March 13,2024 11

Researchers discover a new role for a protein that helps form memories

by Marya Barlow,Virginia Tech(From left) Research scientist Kayla Farrell and Associate Professor Tim Jarome in the School of Animal Sciences are part of a Virginia Tech research team that disco

Updated on: March 13,2024 8

Researchers discover a new role for a protein that helps form memories

by Marya Barlow,Virginia Tech(From left) Research scientist Kayla Farrell and Associate Professor Tim Jarome in the School of Animal Sciences are part of a Virginia Tech research team that disco

Updated on:March 13,2024 8

Researchers create a new tool to rapidly diagnose genetic mutations

byUniversity of CalgaryGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100698Dr. Pierre Billon, Ph.D., was frustrated with the time it took to get g

Updated on: March 13,2024 8

Researchers create a new tool to rapidly diagnose genetic mutations

byUniversity of CalgaryGraphical abstract. Credit:Cell Reports Methods(2024). DOI: 10.1016/j.crmeth.2024.100698Dr. Pierre Billon, Ph.D., was frustrated with the time it took to get g

Updated on:March 13,2024 8

Study shows why women are at greater risk of autoimmune disease

byStanford University Medical CenterCredit: Pixabay/CC0 Public DomainSomewhere between 24 and 50 million Americans have an autoimmune disease, a condition in which the immune system attacks our

Updated on: March 13,2024 13

Study shows why women are at greater risk of autoimmune disease

byStanford University Medical CenterCredit: Pixabay/CC0 Public DomainSomewhere between 24 and 50 million Americans have an autoimmune disease, a condition in which the immune system attacks our

Updated on:March 13,2024 13

Researchers find mitochondrial DNA damage triggers spread of Parkinson's disease-like pathology

byUniversity of CopenhagenComplex I respiratory chain subunits are altered in PD patients and PD models(Ifnb-/-/Ifnar1-/-) due to mtDNA damages.AEnrichment plot of KEGG-OXPHOS

Updated on: March 13,2024 6

Researchers find mitochondrial DNA damage triggers spread of Parkinson's disease-like pathology

byUniversity of CopenhagenComplex I respiratory chain subunits are altered in PD patients and PD models(Ifnb-/-/Ifnar1-/-) due to mtDNA damages.AEnrichment plot of KEGG-OXPHOS

Updated on:March 13,2024 6

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com

Updated on: March 13,2024 13

Researchers identify potential way to treat genetic epilepsy by replacing 'lost' enzyme

byThe Francis Crick InstituteCredit: Pixabay/CC0 Public DomainScientists at the Francis Crick Institute have found a new treatment target for CDKL5 deficiency disorder (CDD), one of the most com

Updated on:March 13,2024 13

Researchers uncover new clues about links between parent age and congenital disorders

byOxford University PressFathers. Credit: Irene Tiemann-Boege /Genome Biology and EvolutionAnew paperinGenome Biology and Evolutionfinds that the link between pater

Updated on: March 13,2024 7

Researchers uncover new clues about links between parent age and congenital disorders

byOxford University PressFathers. Credit: Irene Tiemann-Boege /Genome Biology and EvolutionAnew paperinGenome Biology and Evolutionfinds that the link between pater

Updated on:March 13,2024 7

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on: March 13,2024 13

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on:March 13,2024 13

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Updated on: March 13,2024 6

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Updated on:March 13,2024 6

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc

Updated on: March 13,2024 5

Research provides further evidence that epigenetic changes can cause type 2 diabetes

byLund UniversityStudy design. EPIC array DNA methylation in islets of 25 T2D cases and 75 controls. RNA-seq data were available for 25 T2D cases and 72 controls. Islet DNA methylation was assoc

Updated on:March 13,2024 5

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu

Updated on: March 13,2024 5

Study identifies molecular mechanisms of rare neurodevelopmental disorder

by Melissa Rohman,Northwestern UniversityNeurons cultured for 65 days from healthy cells and those containing the PACS1 syndrome variant both have complex morphology and express neuronal microtu

Updated on:March 13,2024 5

How the brain develops in unborn babies

byUniversity of MontrealProtein–protein interaction networks for maternal, fetal, and famine genes. Deregulated (A) maternal, (B) fetal, or (C) famine genes were used as a query to obtain physic

Updated on: March 13,2024 14

How the brain develops in unborn babies

byUniversity of MontrealProtein–protein interaction networks for maternal, fetal, and famine genes. Deregulated (A) maternal, (B) fetal, or (C) famine genes were used as a query to obtain physic

Updated on:March 13,2024 14