Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Updated on: May 08,2024 5

Biological engineers discover why a promising drug failed in clinical trials

by Anne Trafton,Massachusetts Institute of TechnologyRheumatoid arthritis, which afflicts more than 1 million Americans, is an autoimmune disorder that produces swollen and painful joints, prima

Updated on:May 08,2024 5

COVID-19 hitches a ride on mucus to spread deep into lungs, live imaging shows

by Olivia Dimmer,Northwestern UniversityInverted ALI culture models support MCC. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53791-4The COVID-19 virus spreads via muc

Updated on: December 04,2024 0

COVID-19 hitches a ride on mucus to spread deep into lungs, live imaging shows

by Olivia Dimmer,Northwestern UniversityInverted ALI culture models support MCC. Credit:Nature Communications(2024). DOI: 10.1038/s41467-024-53791-4The COVID-19 virus spreads via muc

Updated on:December 04,2024 0

New methodological approach allows more precise summary of study results

JANUARY 24, 2024byInstitute for Quality and Efficiency in Health CareCredit: Pixabay/CC0 Public DomainBefore new drugs are launched on the market they are tested in clinical studies in which one

Updated on: March 25,2024 4

New methodological approach allows more precise summary of study results

JANUARY 24, 2024byInstitute for Quality and Efficiency in Health CareCredit: Pixabay/CC0 Public DomainBefore new drugs are launched on the market they are tested in clinical studies in which one

Updated on:March 25,2024 4

Uganda study reports first evidence of resistance to vital antimalarial in children with severe malaria

byLondon School of Hygiene & Tropical MedicineCredit: Unsplash/CC0 Public DomainMutations in malarial parasites linked to artemisinin-resistance in Southeast Asia have now been found in Afri

Updated on: December 04,2024 0

Uganda study reports first evidence of resistance to vital antimalarial in children with severe malaria

byLondon School of Hygiene & Tropical MedicineCredit: Unsplash/CC0 Public DomainMutations in malarial parasites linked to artemisinin-resistance in Southeast Asia have now been found in Afri

Updated on:December 04,2024 0

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of

Updated on: October 28,2024 0

Mutation mapping shows errors in protein location are a common cause of disease

by Anika Hazra,University of TorontoCredit:Cell(2024). DOI: 10.1016/j.cell.2024.09.003An international team led by researchers at the University of Toronto and the Broad Institute of

Updated on:October 28,2024 0

GDF11 stimulates EPC mobilization and neovascularization to promote diabetic wound healing

Updated on: October 22,2024 0

GDF11 stimulates EPC mobilization and neovascularization to promote diabetic wound healing

Updated on:October 22,2024 0

Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

 Editors' notesbyElsevierDeposition of laminin into wound bed contributes to blood vessel growth, which in turn, feeds normal skin regeneration. W—wound, BV—blood vessels. Credit:The A

Updated on: March 30,2024 3

Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

 Editors' notesbyElsevierDeposition of laminin into wound bed contributes to blood vessel growth, which in turn, feeds normal skin regeneration. W—wound, BV—blood vessels. Credit:The A

Updated on:March 30,2024 3

Novel pre-clinical models help advance therapeutic development for antibiotic-resistant bacterial infections

by Agency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108875The A*STAR Infectious Diseases Labs (A*STAR

Updated on: April 06,2024 0

Novel pre-clinical models help advance therapeutic development for antibiotic-resistant bacterial infections

by Agency for Science, Technology and Research (A*STAR), SingaporeGraphical abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108875The A*STAR Infectious Diseases Labs (A*STAR

Updated on:April 06,2024 0

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Updated on: March 27,2024 0

Study: PR55α-controlled PP2A inhibits p16 expression and blocks cellular senescence induction

by Impact Journals LLCPR55α level is much lower in human normal tissue specimens of older individuals compared to younger individuals and inversely correlates with p16 levels. Human normal tissue spec

Updated on:March 27,2024 0

Scientists discover a potential way to repair synapses damaged in Alzheimer's disease

FEBRUARY 1, 2024by Buck Institute for Research on AgingThe art depicts the recovery of the functional plasticity at synapses on neurons despite tau-induced toxicity in the brain. Credit: Larissa Brown

Updated on: March 25,2024 11

Scientists discover a potential way to repair synapses damaged in Alzheimer's disease

FEBRUARY 1, 2024by Buck Institute for Research on AgingThe art depicts the recovery of the functional plasticity at synapses on neurons despite tau-induced toxicity in the brain. Credit: Larissa Brown

Updated on:March 25,2024 11

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Updated on: August 26,2024 0

Why clinical trials stop: Researchers find a link between genetic evidence and trial outcome

by Helena Cornu,European Molecular Biology LaboratoryHierarchical clustering of stop reason similarity based on curation from Pak et al. and 447 additional stopped trials due to COVID-19. Credit

Updated on:August 26,2024 0

Green tea may help mitigate harm from hookah smoking, mouse study suggests

JANUARY 16, 2024byRUDN UniversityCredit:Molecules(2023). DOI: 10.3390/molecules28227502Many people consider hookah smoking to be less dangerous than smoking regular cigarettes. Yet h

Updated on: March 15,2024 5

Green tea may help mitigate harm from hookah smoking, mouse study suggests

JANUARY 16, 2024byRUDN UniversityCredit:Molecules(2023). DOI: 10.3390/molecules28227502Many people consider hookah smoking to be less dangerous than smoking regular cigarettes. Yet h

Updated on:March 15,2024 5