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Researchers find mitochondrial DNA damage triggers spread of Parkinson's disease-like pathology

Researchers find mitochondrial DNA damage triggers spread of Parkinson's disease-like pathology

byUniversity of CopenhagenComplex I respiratory chain subunits are altered in PD patients and PD models(Ifnb-/-/Ifnar1-/-) due to mtDNA damages.AEnrichment plot of KEGG-OXPHOS

Researchers find mitochondrial DNA damage triggers spread of Parkinson's disease-like pathology

byUniversity of CopenhagenComplex I respiratory chain subunits are altered in PD patients and PD models(Ifnb-/-/Ifnar1-/-) due to mtDNA damages.AEnrichment plot of KEGG-OXPHOS
Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

 Editors' notesbyElsevierDeposition of laminin into wound bed contributes to blood vessel growth, which in turn, feeds normal skin regeneration. W—wound, BV—blood vessels. Credit:The A

Small RNAs take on the big task of helping skin wounds heal better and faster with minimal scarring

 Editors' notesbyElsevierDeposition of laminin into wound bed contributes to blood vessel growth, which in turn, feeds normal skin regeneration. W—wound, BV—blood vessels. Credit:The A
New research finds microplastics in all human placenta samples tested

New research finds microplastics in all human placenta samples tested

FEBRUARY 20, 2024by Michael Haederle,University of New MexicoCredit: Pixabay/CC0 Public DomainA flurry of recent studies has found that microplastics are present in virtually everything we consu

New research finds microplastics in all human placenta samples tested

FEBRUARY 20, 2024by Michael Haederle,University of New MexicoCredit: Pixabay/CC0 Public DomainA flurry of recent studies has found that microplastics are present in virtually everything we consu
Study examines perceptions of benefits and risks of data sharing in dementia research

Study examines perceptions of benefits and risks of data sharing in dementia research

by Sam Fahmy,Georgia State UniversityCredit: Pixabay/CC0 Public DomainExpectations for data sharing among scientists and returning research results to study subjects have evolved in recent years

Study examines perceptions of benefits and risks of data sharing in dementia research

by Sam Fahmy,Georgia State UniversityCredit: Pixabay/CC0 Public DomainExpectations for data sharing among scientists and returning research results to study subjects have evolved in recent years
New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs

New compound shows early promise for treatment of Lou Gehrig's disease in preclinical models

NOVEMBER 7, 2023by Jaclyn Dunne,Medical University of South CarolinaMitochondrial membrane rearrangements are critical in recruiting p17/PERMIT-CerS1 to mitochondria. Credit:Aging Cell&nbs
Study reveals disparities in use of evidence-based integrative pain management modalities among adults with chronic pain

Study reveals disparities in use of evidence-based integrative pain management modalities among adults with chronic pain

JANUARY 23, 2024byUniversity Hospitals Cleveland Medical CenterCredit: Unsplash/CC0 Public DomainA recent study from researchers at University Hospitals (UH) Connor Whole Health has examined var

Study reveals disparities in use of evidence-based integrative pain management modalities among adults with chronic pain

JANUARY 23, 2024byUniversity Hospitals Cleveland Medical CenterCredit: Unsplash/CC0 Public DomainA recent study from researchers at University Hospitals (UH) Connor Whole Health has examined var
What type of a relationship with an ancient person does a shared DNA fragment imply?

What type of a relationship with an ancient person does a shared DNA fragment imply?

by Shai Carmi and Harald Ringbauer,The ConversationA comparison of one chromosome’s DNA sequence between a 14th-century German Jew and two living people who uploaded their DNA to GEDmatch. Each

What type of a relationship with an ancient person does a shared DNA fragment imply?

by Shai Carmi and Harald Ringbauer,The ConversationA comparison of one chromosome’s DNA sequence between a 14th-century German Jew and two living people who uploaded their DNA to GEDmatch. Each
Interactions between flu subtypes found to predict epidemic severity more than virus evolution

Interactions between flu subtypes found to predict epidemic severity more than virus evolution

by Emily PackerEmily Packer,eLifeAntigenic and genetic evolution of seasonal influenza A(H3N2) viruses, 1997—2019. A-B.Temporal phylogenies of hemagglutinin (H3) and neuraminidase (N2) gene segm

Interactions between flu subtypes found to predict epidemic severity more than virus evolution

by Emily PackerEmily Packer,eLifeAntigenic and genetic evolution of seasonal influenza A(H3N2) viruses, 1997—2019. A-B.Temporal phylogenies of hemagglutinin (H3) and neuraminidase (N2) gene segm
New insight into the protein mutations that cause Rett syndrome

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4

New insight into the protein mutations that cause Rett syndrome

byRockefeller UniversityWorking model for normal MeCP2 function on chromatin and its dysregulation in disease. Credit:Nature Structural & Molecular Biology(2024). DOI: 10.1038/s4
Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

FEBRUARY 6, 2024by Camille Bouchard,The ConversationCredit: Unsplash/CC0 Public DomainI have always been fascinated by genetics, a branch of biology that helps explain everything from the striki

Genetic diseases: How scientists are working to make DNA repair (almost) a piece of cake

FEBRUARY 6, 2024by Camille Bouchard,The ConversationCredit: Unsplash/CC0 Public DomainI have always been fascinated by genetics, a branch of biology that helps explain everything from the striki
Scientists explore the coupling between health span and lifespan in Caenorhabditis

Scientists explore the coupling between health span and lifespan in Caenorhabditis

by Impact Journals LLCPotential effects of compounds on lifespan and health. Credit: 2024 Banse et al.A new research paper waspublishedinAgingtitled, "The coupling between

Scientists explore the coupling between health span and lifespan in Caenorhabditis

by Impact Journals LLCPotential effects of compounds on lifespan and health. Credit: 2024 Banse et al.A new research paper waspublishedinAgingtitled, "The coupling between
HIV: Early treatment is one key to remission

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-

HIV: Early treatment is one key to remission

JANUARY 23, 2024 Editors' notesbyPasteur InstituteThe anti-SIV antibody levels after treatment interruption are associated with the magnitude of antigen stimulation. Kinetics of plasma anti-