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Large Language Models in Drug Development: A Review by Harvard's George Church Lab

Large Language Models in Drug Development: A Review by Harvard's George Church Lab

This article discusses the significant potential of LLMs in understanding disease mechanisms, drug discovery, and clinical trials—three fundamental stages of drug development. This article is authorized by the DrugAI team to medicine.net.

Large Language Models in Drug Development: A Review by Harvard's George Church Lab

This article discusses the significant potential of LLMs in understanding disease mechanisms, drug discovery, and clinical trials—three fundamental stages of drug development. This article is authorized by the DrugAI team to medicine.net.
Complex Innovative Trials: New guideline adoption could get medicines to patients faster

Complex Innovative Trials: New guideline adoption could get medicines to patients faster

byCancer Research UKCredit: CC0 Public DomainComplex Innovative Design (CID) trials could be transformed for the better, following the publication of recommendations, published today in the&nbsp

Complex Innovative Trials: New guideline adoption could get medicines to patients faster

byCancer Research UKCredit: CC0 Public DomainComplex Innovative Design (CID) trials could be transformed for the better, following the publication of recommendations, published today in the&nbsp
Leukemia drug shows potential against metastatic HER2-positive breast cancer

Leukemia drug shows potential against metastatic HER2-positive breast cancer

by Sarah Avery,Duke UniversityGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111268In animal studies led by researchers at Duke Cancer Institute, a drug ap

Leukemia drug shows potential against metastatic HER2-positive breast cancer

by Sarah Avery,Duke UniversityGraphical abstract. Credit:Cell Reports(2022). DOI: 10.1016/j.celrep.2022.111268In animal studies led by researchers at Duke Cancer Institute, a drug ap
Vitamin D found to improve symptoms of toxic erythema during chemotherapy

Vitamin D found to improve symptoms of toxic erythema during chemotherapy

by Melissa Rohman,Northwestern UniversityCredit: CC0 Public DomainHigh doses of vitamin D alleviated symptoms for patients with toxic erythema of chemotherapy (TEC) significantly faster than cur

Vitamin D found to improve symptoms of toxic erythema during chemotherapy

by Melissa Rohman,Northwestern UniversityCredit: CC0 Public DomainHigh doses of vitamin D alleviated symptoms for patients with toxic erythema of chemotherapy (TEC) significantly faster than cur
Researchers identify protein crucial for stem cell survival using editing tool CRISPR

Researchers identify protein crucial for stem cell survival using editing tool CRISPR

byUniversity of Wisconsin-MadisonThe production of proteinα-5 laminin is critical for the self-renewal processes of a human pluripotent stem cell (hPSC)In a multidisciplinary effort, a tea

Researchers identify protein crucial for stem cell survival using editing tool CRISPR

byUniversity of Wisconsin-MadisonThe production of proteinα-5 laminin is critical for the self-renewal processes of a human pluripotent stem cell (hPSC)In a multidisciplinary effort, a tea
Chemotherapy drug paclitaxel also acts as an immune response modulator

Chemotherapy drug paclitaxel also acts as an immune response modulator

by Maria Fernanda Ziegler,FAPESPBy finding that the cancer drug also activates a key cellular receptor in the innate immune system, a study at the Center for Research in Inflammatory Diseases (C

Chemotherapy drug paclitaxel also acts as an immune response modulator

by Maria Fernanda Ziegler,FAPESPBy finding that the cancer drug also activates a key cellular receptor in the innate immune system, a study at the Center for Research in Inflammatory Diseases (C
Research identifies trigger responsible for regenerating hair and skin after trauma

Research identifies trigger responsible for regenerating hair and skin after trauma

Johns Hopkins researchers have identified a novel cell signalling pathway in mice through which mammals can regenerate hair and skin while healing from wounds. The discovery, summarised in an article

Research identifies trigger responsible for regenerating hair and skin after trauma

Johns Hopkins researchers have identified a novel cell signalling pathway in mice through which mammals can regenerate hair and skin while healing from wounds. The discovery, summarised in an article
Study reveals new insights on tissue-dependent roles of JAK signaling in inflammation

Study reveals new insights on tissue-dependent roles of JAK signaling in inflammation

byThe Mount Sinai HospitalMice engineered with a patient gene (JAK1 GOF: Neuron) show less lung inflammation, fewer immune cells, and reduced mucous production compared to controls. Credit: Kim

Study reveals new insights on tissue-dependent roles of JAK signaling in inflammation

byThe Mount Sinai HospitalMice engineered with a patient gene (JAK1 GOF: Neuron) show less lung inflammation, fewer immune cells, and reduced mucous production compared to controls. Credit: Kim
Statins may do double duty on heart disease and cancer

Statins may do double duty on heart disease and cancer

Roger Ashford, Getty ImagesAbout 40 million adults in the U.S. take a statin to lower their cholesterol and reduce the risk for heart disease. They might also be getting an added anti-cancer benefit,

Statins may do double duty on heart disease and cancer

Roger Ashford, Getty ImagesAbout 40 million adults in the U.S. take a statin to lower their cholesterol and reduce the risk for heart disease. They might also be getting an added anti-cancer benefit,
 previously unknown qualities of a gene vital to a cell's mitochondrial structure and function

previously unknown qualities of a gene vital to a cell's mitochondrial structure and function

by Rachel Sauer,University of Colorado at BoulderModel of the human S-OPA1 bound to membranes. Credit:Nature(2023). DOI: 10.1038/s41586-023-06441-6A key takeaway from first-year biol

previously unknown qualities of a gene vital to a cell's mitochondrial structure and function

by Rachel Sauer,University of Colorado at BoulderModel of the human S-OPA1 bound to membranes. Credit:Nature(2023). DOI: 10.1038/s41586-023-06441-6A key takeaway from first-year biol