A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo

Updated on: April 02,2024 14

A new vision for AAV-delivered gene therapies

by Benjamin Boettner,Harvard UniversityAAVs with TLR9-inhibitory sequences incorporated into their genomes allowed significantly higher expression of a linked fluorescent reporter gene in the mo

Updated on:April 02,2024 14

New antibiotic zosurabalpin shows promise against drug-resistant bacteria: An expert explains

by Jonathan Cox,The ConversationCredit: Pixabay/CC0 Public DomainResearchers haveidentifiedan entirely new class of antibiotic that can kill bacteria that are resistant to most curre

Updated on: January 26,2024 10

New antibiotic zosurabalpin shows promise against drug-resistant bacteria: An expert explains

by Jonathan Cox,The ConversationCredit: Pixabay/CC0 Public DomainResearchers haveidentifiedan entirely new class of antibiotic that can kill bacteria that are resistant to most curre

Updated on:January 26,2024 10

Dicer enzyme cuts down on fats

by Ludwig Maximilian University of MunichDicer knockout in macrophages (right) accelerates atherosclerosis. Credit: Yuanyuan Wei, LMUThe enzyme Dicer cleaves long precursors into short RNA molecu

Updated on: April 12,2024 20

Dicer enzyme cuts down on fats

by Ludwig Maximilian University of MunichDicer knockout in macrophages (right) accelerates atherosclerosis. Credit: Yuanyuan Wei, LMUThe enzyme Dicer cleaves long precursors into short RNA molecu

Updated on:April 12,2024 20

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi

Updated on: January 26,2024 19

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi

Updated on:January 26,2024 19

Popular blood thinner associated with higher risk of bleeding complications

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhen diagnosed with a blood clot or atrial fibrillation, patients are often prescribed anticoagulants, or blood thinners, to prevent a fu

Updated on: January 26,2024 10

Popular blood thinner associated with higher risk of bleeding complications

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainWhen diagnosed with a blood clot or atrial fibrillation, patients are often prescribed anticoagulants, or blood thinners, to prevent a fu

Updated on:January 26,2024 10

Psychoactive drug ibogaine found to effectively treat traumatic brain injury in special operations military vets

byStanford University Medical CenterCredit: RDNE Stock project from PexelsFor military veterans, many of the deepest wounds of war are invisible: Traumatic brain injuries resulting from head tra

Updated on: January 26,2024 11

Psychoactive drug ibogaine found to effectively treat traumatic brain injury in special operations military vets

byStanford University Medical CenterCredit: RDNE Stock project from PexelsFor military veterans, many of the deepest wounds of war are invisible: Traumatic brain injuries resulting from head tra

Updated on:January 26,2024 11

3-D printed pill samples gut microbiome to aid diagnosis and treatment

by Tufts UniversityBacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill. Credit: Nano Lab, Tufts UniversityA research team led by Tufts University eng

Updated on: April 02,2024 12

3-D printed pill samples gut microbiome to aid diagnosis and treatment

by Tufts UniversityBacteria in the gut are pulled into the helical channels by an osmotic 'pump' in the pill. Credit: Nano Lab, Tufts UniversityA research team led by Tufts University eng

Updated on:April 02,2024 12

Poison center calls related to injected weight-loss drugs up 1,500%

by Nancy Clanton, The Atlanta Journal-ConstitutionCredit: Pixabay/CC0 Public DomainAmerica's Poison Centers reported nearly 3,000 calls this year involving the weight loss drug semaglutide—a 15-fo

Updated on: January 26,2024 10

Poison center calls related to injected weight-loss drugs up 1,500%

by Nancy Clanton, The Atlanta Journal-ConstitutionCredit: Pixabay/CC0 Public DomainAmerica's Poison Centers reported nearly 3,000 calls this year involving the weight loss drug semaglutide—a 15-fo

Updated on:January 26,2024 10

Putting the brakes on chronic inflammation: Study discovers link between two key pathways

by Weill Cornell Medical CollegeA single-cell atlas of IL-23 responses in the small intestine identifies CTLA-4+ILC3s. Credit:Nature(2024). DOI: 10.1038/s41586-024-07537-3Scient

Updated on: June 15,2024 6

Putting the brakes on chronic inflammation: Study discovers link between two key pathways

by Weill Cornell Medical CollegeA single-cell atlas of IL-23 responses in the small intestine identifies CTLA-4+ILC3s. Credit:Nature(2024). DOI: 10.1038/s41586-024-07537-3Scient

Updated on:June 15,2024 6

Considering taking a weight-loss drug like Ozempic? Here are some potential risks and benefits

Considering taking a weight-loss drug like Ozempic? Here are some potential risks and benefitsby Lauren Ball and Emily Burch,The ConversationCredit: Unsplash/CC0 Public DomainAfter weight-loss d

Updated on: April 06,2024 0

Considering taking a weight-loss drug like Ozempic? Here are some potential risks and benefits

Considering taking a weight-loss drug like Ozempic? Here are some potential risks and benefitsby Lauren Ball and Emily Burch,The ConversationCredit: Unsplash/CC0 Public DomainAfter weight-loss d

Updated on:April 06,2024 0

New antibiotic slays deadly superbug in early trial

by Robin FosterResearchers report that a new type of antibiotic has proved its mettle against a deadly superbug.Acinetobacter baumannii, abacteriathat goes by the nickname CRAB when it bec

Updated on: January 26,2024 8

New antibiotic slays deadly superbug in early trial

by Robin FosterResearchers report that a new type of antibiotic has proved its mettle against a deadly superbug.Acinetobacter baumannii, abacteriathat goes by the nickname CRAB when it bec

Updated on:January 26,2024 8

Steroid drugs used for HRT can combat E. coli and MRSA

by University of KentOverview of in silico screening methodology including generation of a structural template for cytochrome bd-I. A, Published Escherichia coli cytochrome bd-I structure (PDBid

Updated on: March 20,2024 12

Steroid drugs used for HRT can combat E. coli and MRSA

by University of KentOverview of in silico screening methodology including generation of a structural template for cytochrome bd-I. A, Published Escherichia coli cytochrome bd-I structure (PDBid

Updated on:March 20,2024 12