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Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (

Mantle cell lymphoma patients see improved outcomes with oral combination of ibrutinib and venetoclax

byUniversity of Texas M. D. Anderson Cancer CenterCredit: Pixabay/CC0 Public DomainThe targeted therapy combination of ibrutinib and venetoclax significantly improved progression-free survival (
Deciphering the role of bitter and astringent polyphenols in promoting well-being

Deciphering the role of bitter and astringent polyphenols in promoting well-being

by Shibaura Institute of TechnologyDietary uptake of polyphenols alters the gut microflora and stimulates the secretion of specific hormones that induce cross-talk with the brain via the sensory

Deciphering the role of bitter and astringent polyphenols in promoting well-being

by Shibaura Institute of TechnologyDietary uptake of polyphenols alters the gut microflora and stimulates the secretion of specific hormones that induce cross-talk with the brain via the sensory
Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N

Mechanical constraints guide spatial pattern of glioblastoma cancer stem cells

by Shanghai Jiao Tong University Journal CenterOne photo from the article titled "Mechanical constraints in tumor guide emergent spatial patterns of glioblastoma cancer stem cells" Credit: N
Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

byJohns Hopkins University School of MedicineNeuronal membrane proteasomes are labeled with a red compound and appear in a subset of sensory neurons that are labeled with green compound. Note, n

Cell's 'garbage disposal' may have another role: Helping neurons near skin sense the environment

byJohns Hopkins University School of MedicineNeuronal membrane proteasomes are labeled with a red compound and appear in a subset of sensory neurons that are labeled with green compound. Note, n
Imetelstat leads to durable red blood cell transfusion independence

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi
Scientists develop 'safe' bone grafts from cow bones to heal bone fractures and injuries

Scientists develop 'safe' bone grafts from cow bones to heal bone fractures and injuries

byUniversity of SharjahRepresentative images of immunohistochemical staining of DMB and DCC implantation sites to visualize the intensity distribution of osteogenic factors. Credit:PLOS ON

Scientists develop 'safe' bone grafts from cow bones to heal bone fractures and injuries

byUniversity of SharjahRepresentative images of immunohistochemical staining of DMB and DCC implantation sites to visualize the intensity distribution of osteogenic factors. Credit:PLOS ON
Autophagy-tethering compounds may open new directions in targeted drug discovery

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting

Autophagy-tethering compounds may open new directions in targeted drug discovery

byScience China Press(A) Molecular glue ATTECs are targeting polyQ proteins in neurodegenerative disorders. (B) Bifunctional ATTECs targeting oncoprotein BRD4. (C) Bifunctional ATTECs targeting
Choosing over the counter drugs for COVID 19? It's complicated

Choosing over the counter drugs for COVID 19? It's complicated

byFlorida Atlantic UniversityResearchers take a closer look at both the potential benefits and risks of acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs)—such as ibuprofen, as well a

Choosing over the counter drugs for COVID 19? It's complicated

byFlorida Atlantic UniversityResearchers take a closer look at both the potential benefits and risks of acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs)—such as ibuprofen, as well a
Combined antibiotics more effective against Lyme disease: Study

Combined antibiotics more effective against Lyme disease: Study

by Leslie Tate,Tulane UniversityThe study findings could pave the way for improved Lyme disease treatments, particularly in persistent cases, said lead researcher Monica Embers, PhD, associate p

Combined antibiotics more effective against Lyme disease: Study

by Leslie Tate,Tulane UniversityThe study findings could pave the way for improved Lyme disease treatments, particularly in persistent cases, said lead researcher Monica Embers, PhD, associate p
Plozasiran reduces triglyceride levels by 74% at 24 weeks

Plozasiran reduces triglyceride levels by 74% at 24 weeks

byAmerican College of CardiologyCredit: CC0 Public DomainIn patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran red

Plozasiran reduces triglyceride levels by 74% at 24 weeks

byAmerican College of CardiologyCredit: CC0 Public DomainIn patients with severely elevated triglyceride levels at risk for developing acute pancreatitis, the investigational drug plozasiran red
Off-label use of a common antibiotic to treat muscular dystrophy

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads

Off-label use of a common antibiotic to treat muscular dystrophy

byOsaka UniversityMechanisms of molecular pathology and erythromycin treatment in myotonic dystrophy type 1 In myotonic dystrophy type 1, aberrant RNA transcribed from the mutant DMPK gene leads