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Decoding Organ Aging: Plasma Proteome Insights for Health and Disease

Decoding Organ Aging: Plasma Proteome Insights for Health and Disease

This study introduces a novel framework for modeling organ health and biological aging using plasma proteomics, offering a more nuanced understanding of aging at the organ level.

Decoding Organ Aging: Plasma Proteome Insights for Health and Disease

This study introduces a novel framework for modeling organ health and biological aging using plasma proteomics, offering a more nuanced understanding of aging at the organ level.
Drug-drug interactions seen in 21.4% of children with medication exposure

Drug-drug interactions seen in 21.4% of children with medication exposure

by Elana GotkineMore than 20% of children with two or more medication exposures experience major drug-drug interactions (DDIs) annually, according to a study published online Jan. 4 inPediatrics

Drug-drug interactions seen in 21.4% of children with medication exposure

by Elana GotkineMore than 20% of children with two or more medication exposures experience major drug-drug interactions (DDIs) annually, according to a study published online Jan. 4 inPediatrics
Deciphering the role of bitter and astringent polyphenols in promoting well-being

Deciphering the role of bitter and astringent polyphenols in promoting well-being

by Shibaura Institute of TechnologyDietary uptake of polyphenols alters the gut microflora and stimulates the secretion of specific hormones that induce cross-talk with the brain via the sensory

Deciphering the role of bitter and astringent polyphenols in promoting well-being

by Shibaura Institute of TechnologyDietary uptake of polyphenols alters the gut microflora and stimulates the secretion of specific hormones that induce cross-talk with the brain via the sensory
Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02

Scientists identify a molecular anchor that stabilizes mitochondria near synapses to support memory formation

byMax Planck Florida Institute for NeuroscienceIdentifying proteins required for mitochondria-actin tethering in dendrites. Credit:Nature Communications(2024). DOI: 10.1038/s41467-02
Study of palliative care demonstrates scalable strategy to increase support for seriously ill patients in hospital

Study of palliative care demonstrates scalable strategy to increase support for seriously ill patients in hospital

JANUARY 16, 2024byPerelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainOrdering a palliative care consultation by "default"—via an automatic o

Study of palliative care demonstrates scalable strategy to increase support for seriously ill patients in hospital

JANUARY 16, 2024byPerelman School of Medicine at the University of PennsylvaniaCredit: Unsplash/CC0 Public DomainOrdering a palliative care consultation by "default"—via an automatic o
Parkinson's disease clinical trial tests exercise regimen to improve movement

Parkinson's disease clinical trial tests exercise regimen to improve movement

MAY 17, 2023by Erik Robinson,Oregon Health & Science UniversityLinda Cherney demonstrates an OHSU training protocol designed to improve the ability to turn for people with Parkinson’s diseas

Parkinson's disease clinical trial tests exercise regimen to improve movement

MAY 17, 2023by Erik Robinson,Oregon Health & Science UniversityLinda Cherney demonstrates an OHSU training protocol designed to improve the ability to turn for people with Parkinson’s diseas
New genome editing tools unlock possibilities for precision medicine

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a

New genome editing tools unlock possibilities for precision medicine

by Stephan Wiegand,Dresden University of TechnologyDesign of ZFDs for the loxF8 genomic locus. a, Genomic sequences flanking loxF8. Binding sites of the designed ZFDs upstream (orange, ZFL1–2) a
FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)

FoxO6-mediated ApoC3 upregulation promotes hepatic steatosis and hyperlipidemia in HFD aged rats: Study

by Impact Journals LLCAging-related serum changes in insulin resistance and lipogenesis. (A) Glucose levels, (B) insulin levels, and (C) HOMA-IR scores were determined. (D) FFA (free fatty acid), (E)
New technique reveals earliest signs of genetic mutations

New technique reveals earliest signs of genetic mutations

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these chan

New technique reveals earliest signs of genetic mutations

by NYU Langone HealthCredit: Unsplash/CC0 Public DomainMutations are changes in the molecular "letters" that make up the DNA code, the blueprint for all living cells. Some of these chan
Novel pancreatic cancer organoids show promise for effective screening of anticancer drugs

Novel pancreatic cancer organoids show promise for effective screening of anticancer drugs

byUniversity of TokyoGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113420Pancreatic ductal adenocarcinoma (PDAC), that arises from pancreatic epithelial c

Novel pancreatic cancer organoids show promise for effective screening of anticancer drugs

byUniversity of TokyoGraphical Abstract. Credit:Cell Reports(2023). DOI: 10.1016/j.celrep.2023.113420Pancreatic ductal adenocarcinoma (PDAC), that arises from pancreatic epithelial c
Migraine sufferers in England may soon be able to access a preventative drug: Atogepant

Migraine sufferers in England may soon be able to access a preventative drug: Atogepant

by Anna Andreou,The ConversationCredit: Unsplash/CC0 Public DomainA drug that can help prevent migraines could soon be available on the NHS. Atogepant (brand name: Aquipta) was recently recommen

Migraine sufferers in England may soon be able to access a preventative drug: Atogepant

by Anna Andreou,The ConversationCredit: Unsplash/CC0 Public DomainA drug that can help prevent migraines could soon be available on the NHS. Atogepant (brand name: Aquipta) was recently recommen