Team develops tools and techniques to explore cancer signals at the subcellular level

by Jerry Grillo,Georgia Institute of TechnologyGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104980This year, about 240,000 people in the U.S. will discover the

Updated on: January 08,2024 9

Team develops tools and techniques to explore cancer signals at the subcellular level

by Jerry Grillo,Georgia Institute of TechnologyGraphical abstract. Credit:iScience(2022). DOI: 10.1016/j.isci.2022.104980This year, about 240,000 people in the U.S. will discover the

Updated on:January 08,2024 9

Researchers discover deep structural biology connections that help improve CAR therapy

byChildren's Hospital of PhiladelphiaCredit: Nikolaos SgourakisChimeric antigen receptors (CARs) have opened up an exciting new field of therapeutic advancements for rare and difficult-to-tr

Updated on: January 26,2024 11

Researchers discover deep structural biology connections that help improve CAR therapy

byChildren's Hospital of PhiladelphiaCredit: Nikolaos SgourakisChimeric antigen receptors (CARs) have opened up an exciting new field of therapeutic advancements for rare and difficult-to-tr

Updated on:January 26,2024 11

Discovery could lead to 'kinder' treatment for childhood neuroblastoma

by University of CambridgeA ball of neuroblastoma cells forming mature nerves after drug treatment. Credit: Kirsty Ferguson/Developmental CellChildren with neuroblastoma—responsible for 15% of ca

Updated on: March 23,2024 20

Discovery could lead to 'kinder' treatment for childhood neuroblastoma

by University of CambridgeA ball of neuroblastoma cells forming mature nerves after drug treatment. Credit: Kirsty Ferguson/Developmental CellChildren with neuroblastoma—responsible for 15% of ca

Updated on:March 23,2024 20

Study reviews the role of a ribonucleic acid 'MALAT1' in hematological malignancies

by Cactus CommunicationsRecent studies have shown that an abnormally high expression of MALAT1 in blood cancer cells could aid the chemotherapeutic resistance development through multiple intermolecul

Updated on: April 28,2024 0

Study reviews the role of a ribonucleic acid 'MALAT1' in hematological malignancies

by Cactus CommunicationsRecent studies have shown that an abnormally high expression of MALAT1 in blood cancer cells could aid the chemotherapeutic resistance development through multiple intermolecul

Updated on:April 28,2024 0

Denosumab linked to severe hypocalcemia in dialysis-dependent seniors

by Elana GotkineFor female dialysis-dependent patients aged 65 years or older treated for osteoporosis, denosumab is associated with an increased incidence of severe or very severe hypocalcemia, accor

Updated on: March 26,2024 19

Denosumab linked to severe hypocalcemia in dialysis-dependent seniors

by Elana GotkineFor female dialysis-dependent patients aged 65 years or older treated for osteoporosis, denosumab is associated with an increased incidence of severe or very severe hypocalcemia, accor

Updated on:March 26,2024 19

Exome sequencing identifies those with cancer predisposition syndromes missed by current screening guidelines

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainAmong individuals who consented to whole-exome sequencing and were identified as carriers of predisposition genes for h

Updated on: January 08,2024 9

Exome sequencing identifies those with cancer predisposition syndromes missed by current screening guidelines

byAmerican Association for Cancer ResearchCredit: Pixabay/CC0 Public DomainAmong individuals who consented to whole-exome sequencing and were identified as carriers of predisposition genes for h

Updated on:January 08,2024 9

Study shows promise of new anti-KRAS drug for pancreatic cancer

by Perelman School of Medicine at the University of PennsylvaniaMRTX1133 reduces metastatic burden in a tail vein model. (A) Representative brightfield images of lungs from vehicle and MRTX1133 (

Updated on: January 30,2024 12

Study shows promise of new anti-KRAS drug for pancreatic cancer

by Perelman School of Medicine at the University of PennsylvaniaMRTX1133 reduces metastatic burden in a tail vein model. (A) Representative brightfield images of lungs from vehicle and MRTX1133 (

Updated on:January 30,2024 12

Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri

Updated on: January 08,2024 9

Vitamin C may hold the key to improve efficacy of dendritic cell-derived anticancer cell therapies

byJosep Carreras Leukaemia Research InstituteVitamin C-mediated dendritic cell DNA methylome remodeling. (A) Scheme depicting the experimental setup. Monocytes (MO) were differentiated to dendri

Updated on:January 08,2024 9

Prostate cancer testing in Sweden—a study on cost and effectiveness

byKarolinska InstitutetShuang Hao, PhD student at the Department of Medical Epidemiology and Biostatistics. Credit: Stefan ZimmermanProstate cancer constitutes an essential public health issue,

Updated on: January 03,2024 6

Prostate cancer testing in Sweden—a study on cost and effectiveness

byKarolinska InstitutetShuang Hao, PhD student at the Department of Medical Epidemiology and Biostatistics. Credit: Stefan ZimmermanProstate cancer constitutes an essential public health issue,

Updated on:January 03,2024 6

Study investigates link between oropharyngeal cancer and sexual behavior

byLeipzig UniversityVenn diagrams showing the distribution of self-reported high-risk sexual behavior (HR-SB) among N = 188 propensity-score-matched healthy adults and among N = 94 oropharyngeal

Updated on: January 22,2024 10

Study investigates link between oropharyngeal cancer and sexual behavior

byLeipzig UniversityVenn diagrams showing the distribution of self-reported high-risk sexual behavior (HR-SB) among N = 188 propensity-score-matched healthy adults and among N = 94 oropharyngeal

Updated on:January 22,2024 10

New hormone therapies before surgery may improve outcomes in high-risk prostate cancer

byWolters Kluwer HealthTime to BCR in the neo-RP and RP cohorts after IPTW. The number of participants at risk are based on unweighted population. Credit:Journal of Urology(2022). DO

Updated on: January 04,2024 9

New hormone therapies before surgery may improve outcomes in high-risk prostate cancer

byWolters Kluwer HealthTime to BCR in the neo-RP and RP cohorts after IPTW. The number of participants at risk are based on unweighted population. Credit:Journal of Urology(2022). DO

Updated on:January 04,2024 9

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on: January 23,2024 19

Enzyme inhibition promotes bone formation and curbs the development of bone metastases, study finds

byGerman Cancer Research CenterNegative regulation of bone formation by TAM receptor MERTK.amRNA expression analysis of TAM receptor familyMertk,Tyro3,Axl,Gas

Updated on:January 23,2024 19