Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on: January 04,2024 12

Dual checkpoint inhibitor blockade shows promise as first-line and salvage therapy for Merkel cell carcinoma patients

byH. Lee Moffitt Cancer Center & Research InstituteMicrograph of a lung primary small cell carcinoma, a type of carcinoma. Credit: WikipediaMerkel cell carcinoma is a rare but aggressive for

Updated on:January 04,2024 12

Research shows PSMA PET/CT imaging changes management for close to 50% of prostate cancer patients

by Society of Nuclear Medicine and Molecular ImagingGraphical Abstract: Patients with detectable PSA (0.2-2.0 ng/mL) post-prostatectomy considered for salvage radiotherapy undergoing18F-DCFPyL P

Updated on: January 22,2024 15

Research shows PSMA PET/CT imaging changes management for close to 50% of prostate cancer patients

by Society of Nuclear Medicine and Molecular ImagingGraphical Abstract: Patients with detectable PSA (0.2-2.0 ng/mL) post-prostatectomy considered for salvage radiotherapy undergoing18F-DCFPyL P

Updated on:January 22,2024 15

Drug combination shows potential in aggressive leukemia

by Blake Belden,Virginia Commonwealth UniversityAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainAcute myeloid leukemia (AML) is an aggressive form of cancer that originates in

Updated on: December 28,2023 10

Drug combination shows potential in aggressive leukemia

by Blake Belden,Virginia Commonwealth UniversityAcute myelocytic leukemia (AML). Credit: Unsplash/CC0 Public DomainAcute myeloid leukemia (AML) is an aggressive form of cancer that originates in

Updated on:December 28,2023 10

Discovery of a gene that could be key for reducing breast cancer risk

by University of OtagoCharacterization of SULT1A1. a Genomic viewer (UCSC) of the SULT1A1 gene locus with copy number variants; deletion (red) and duplication (blue). b Dosage effect in breast tu

Updated on: January 30,2024 16

Discovery of a gene that could be key for reducing breast cancer risk

by University of OtagoCharacterization of SULT1A1. a Genomic viewer (UCSC) of the SULT1A1 gene locus with copy number variants; deletion (red) and duplication (blue). b Dosage effect in breast tu

Updated on:January 30,2024 16

Wildfire exposure decreases chances of survival for vulnerable cancer patients, study shows

by Rob Spahr,Emory UniversityCredit: Unsplash/CC0 Public DomainPeople exposed to a wildfire within a year after having lung cancer surgery have significantly lower chances of survival compared t

Updated on: January 16,2024 16

Wildfire exposure decreases chances of survival for vulnerable cancer patients, study shows

by Rob Spahr,Emory UniversityCredit: Unsplash/CC0 Public DomainPeople exposed to a wildfire within a year after having lung cancer surgery have significantly lower chances of survival compared t

Updated on:January 16,2024 16

Researchers discover marker that may show when a type of skin cancer is preparing to metastasize

by Center for Genomic RegulationFrom left to right: Noemí Haro, Óscar Pozo, Inma Hernández-Muñoz, Evelyn Andrades, Paloma Torres & Ramon Pujol. Credit: Hospital de Mar/IMIMCells that form cutaneou

Updated on: February 20,2024 18

Researchers discover marker that may show when a type of skin cancer is preparing to metastasize

by Center for Genomic RegulationFrom left to right: Noemí Haro, Óscar Pozo, Inma Hernández-Muñoz, Evelyn Andrades, Paloma Torres & Ramon Pujol. Credit: Hospital de Mar/IMIMCells that form cutaneou

Updated on:February 20,2024 18

New study challenges belief that opioids are effective at treating cancer pain

by Annie Slinn,University of WarwickEffect of geographic ancestry on CYP2D6 genotype. CYP2D6 indicates cytochrome P450 2D6. Adapted from information in Table1 of Gaedigk etal., 2017.

Updated on: December 30,2023 8

New study challenges belief that opioids are effective at treating cancer pain

by Annie Slinn,University of WarwickEffect of geographic ancestry on CYP2D6 genotype. CYP2D6 indicates cytochrome P450 2D6. Adapted from information in Table1 of Gaedigk etal., 2017.

Updated on:December 30,2023 8

Research identifies new way to halt pancreatic cancer invasion by targeting healthy cells

by Queen Mary, University of LondonInhibition of FGFR1 limits invasion in pre-clinical models of PDAC.ARepresentative H&E images of MIA PaCa-2: PS1 organotypics treated with 100 n

Updated on: February 20,2024 14

Research identifies new way to halt pancreatic cancer invasion by targeting healthy cells

by Queen Mary, University of LondonInhibition of FGFR1 limits invasion in pre-clinical models of PDAC.ARepresentative H&E images of MIA PaCa-2: PS1 organotypics treated with 100 n

Updated on:February 20,2024 14

New research sheds light on how mesothelioma develops

byUniversity of MarylandAn asbestos fiber (stained blue) in lung tissue being surrounded by macrophages. Credit: Centers for Disease Control and PreventionMesothelioma has been a high-profile di

Updated on: January 13,2024 19

New research sheds light on how mesothelioma develops

byUniversity of MarylandAn asbestos fiber (stained blue) in lung tissue being surrounded by macrophages. Credit: Centers for Disease Control and PreventionMesothelioma has been a high-profile di

Updated on:January 13,2024 19

Specific sequence of drugs reduces cost of treating metastatic breast cancer while preserving quality of life

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainGiving standard chemotherapy drugs in a specific sequence for some types of metastatic breast cancer can help reduce

Updated on: January 07,2024 9

Specific sequence of drugs reduces cost of treating metastatic breast cancer while preserving quality of life

byUNC Lineberger Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainGiving standard chemotherapy drugs in a specific sequence for some types of metastatic breast cancer can help reduce

Updated on:January 07,2024 9

Experimental brain cancer drug fast tracked in clinical trials

byUniversity of South AustraliaProfessor Shudong Wang. Credit: University of South AustraliaAn experimental drug being trialed for advanced solid tumors, including the most aggressive brain canc

Updated on: January 04,2024 16

Experimental brain cancer drug fast tracked in clinical trials

byUniversity of South AustraliaProfessor Shudong Wang. Credit: University of South AustraliaAn experimental drug being trialed for advanced solid tumors, including the most aggressive brain canc

Updated on:January 04,2024 16

Magrolimab/Azacitidine Combo Shows Efficacy for Untreated TP53-Mutant AML

December 2023Leah LawrencePatients with previously untreated acute myeloid leukemia (AML) who were not candidates for intensive chemotherapy experienced disease response when treated with a combinatio

Updated on: February 18,2024 8

Magrolimab/Azacitidine Combo Shows Efficacy for Untreated TP53-Mutant AML

December 2023Leah LawrencePatients with previously untreated acute myeloid leukemia (AML) who were not candidates for intensive chemotherapy experienced disease response when treated with a combinatio

Updated on:February 18,2024 8