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Public Health & Prevention
Focuses on global human health and epidemic prevention.
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ISG15 deficiency linked to antiviral immunity in humans

ISG15 deficiency linked to antiviral immunity in humans

(HealthDay)—Investigators describe a strategy for development of a broad-spectrum anti-viral agent. Their research was published online May 19 inNature Communications.Noting that studies in mice

ISG15 deficiency linked to antiviral immunity in humans

(HealthDay)—Investigators describe a strategy for development of a broad-spectrum anti-viral agent. Their research was published online May 19 inNature Communications.Noting that studies in mice
HIV: an innovative therapeutic breakthrough to optimize the immune system

HIV: an innovative therapeutic breakthrough to optimize the immune system

by Institut national de la recherche scientifique - INRSINRS Professor Julien vanGrevenynghe, expert in immunology and virology, and doctoral student Hamza Loucif, first author of the paper. Cre

HIV: an innovative therapeutic breakthrough to optimize the immune system

by Institut national de la recherche scientifique - INRSINRS Professor Julien vanGrevenynghe, expert in immunology and virology, and doctoral student Hamza Loucif, first author of the paper. Cre
IgA antibodies seem to protect unvaccinated against COVID-19

IgA antibodies seem to protect unvaccinated against COVID-19

by University of GothenburgT-cell populations that responded to stimulation with SARS-CoV-2 peptides. PBMC from individuals with IgG-dominated, IgA-dominated, and no antibody response to Covid-19

IgA antibodies seem to protect unvaccinated against COVID-19

by University of GothenburgT-cell populations that responded to stimulation with SARS-CoV-2 peptides. PBMC from individuals with IgG-dominated, IgA-dominated, and no antibody response to Covid-19
Type III interferon in COVID-19: Protective or harmful?

Type III interferon in COVID-19: Protective or harmful?

by Children's Hospital BostonCredit: CC0 Public DomainOur immune system makes interferons and other cytokines to help us fight viruses. But in COVID-19, we've learned that they can also c

Type III interferon in COVID-19: Protective or harmful?

by Children's Hospital BostonCredit: CC0 Public DomainOur immune system makes interferons and other cytokines to help us fight viruses. But in COVID-19, we've learned that they can also c
COVID-19: Anti-viral strategy with double effect

COVID-19: Anti-viral strategy with double effect

by Brigitte Holfelder,Max Planck SocietyThe protease PLpro of Sars-CoV-2 plays a central role in the viral life cycle. By cleaving also proteins of infected cells, PLpro interferes with the inna

COVID-19: Anti-viral strategy with double effect

by Brigitte Holfelder,Max Planck SocietyThe protease PLpro of Sars-CoV-2 plays a central role in the viral life cycle. By cleaving also proteins of infected cells, PLpro interferes with the inna
COVID-19 vaccination shown to protect people with blood cancer

COVID-19 vaccination shown to protect people with blood cancer

by Ludwig Maximilian University of MunichStudy time chart, anti-spike IgG levels and IgG avidity in individuals with hematologic neoplasia and in healthy individuals at different time points afte

COVID-19 vaccination shown to protect people with blood cancer

by Ludwig Maximilian University of MunichStudy time chart, anti-spike IgG levels and IgG avidity in individuals with hematologic neoplasia and in healthy individuals at different time points afte
COVID-19 cytokine storms may prevent a durable immune response

COVID-19 cytokine storms may prevent a durable immune response

by Rachel Leeson,Massachusetts General HospitalCredit: CC0 Public DomainShiv Pillai, MD, Ph.D., investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical Schoo

COVID-19 cytokine storms may prevent a durable immune response

by Rachel Leeson,Massachusetts General HospitalCredit: CC0 Public DomainShiv Pillai, MD, Ph.D., investigator in the Ragon Institute of MGH, MIT and Harvard and professor at Harvard Medical Schoo
Antibodies elicited by COVID-19 vaccination effective against delta variant

Antibodies elicited by COVID-19 vaccination effective against delta variant

by Tamara Bhandari,Washington University School of Medicine in St. LouisCherry Grimmett, a BJC HealthCare security officer, receives her first dose of the Pfizer COVID-19 vaccine in December 202

Antibodies elicited by COVID-19 vaccination effective against delta variant

by Tamara Bhandari,Washington University School of Medicine in St. LouisCherry Grimmett, a BJC HealthCare security officer, receives her first dose of the Pfizer COVID-19 vaccine in December 202
T-cell abnormalities in severe COVID-19 cases

T-cell abnormalities in severe COVID-19 cases

by Kumamoto UniversityA major difference between mild and severe cases of COVID-19 may be the extreme activation of T cells as they react to the virus. In mild cases, T cell activation is slowed

T-cell abnormalities in severe COVID-19 cases

by Kumamoto UniversityA major difference between mild and severe cases of COVID-19 may be the extreme activation of T cells as they react to the virus. In mild cases, T cell activation is slowed
COVID-19 vaccine responses to be studied in people with immune deficits

COVID-19 vaccine responses to be studied in people with immune deficits

by NIH/National Institute of Allergy and Infectious DiseasesZebra-print ribbon, a symbol for awareness of primary immunodeficiencies and other rare diseases. Credit: NIAIDA study assessing how pe

COVID-19 vaccine responses to be studied in people with immune deficits

by NIH/National Institute of Allergy and Infectious DiseasesZebra-print ribbon, a symbol for awareness of primary immunodeficiencies and other rare diseases. Credit: NIAIDA study assessing how pe
Does the COVID-19 cytokine storm exist?

Does the COVID-19 cytokine storm exist?

by Radboud UniversityCredit: CC0 Public DomainInflammatory proteins, also known as cytokines, play a crucial role in the immune response. If this immune response is too strong, a phenomenon known

Does the COVID-19 cytokine storm exist?

by Radboud UniversityCredit: CC0 Public DomainInflammatory proteins, also known as cytokines, play a crucial role in the immune response. If this immune response is too strong, a phenomenon known