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Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K

Study identifies epigenetic 'switches' that regulate the developmental trajectories of single cells

by Ingrid Fadelli , Medical XpressAnalysis of the developmental cell atlas. a, Workflow to obtain single-cell RNA (scRNA) expression and CUT&Tag data for three histone modifications (H3K27me3, H3K
New technique for revealing genetic repeats yields surprising insights into Huntington's disease

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani

New technique for revealing genetic repeats yields surprising insights into Huntington's disease

byRockefeller UniversityCredit:Neuron(2024). DOI: 10.1016/j.neuron.2023.12.009Neurodegenerative diseases are among the most complex human ailments, and their exact causes and mechani
Researchers identify peptides produced by the proteasome that degrade damaged proteins

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo

Researchers identify peptides produced by the proteasome that degrade damaged proteins

FEBRUARY 14, 2024by Carmen Rotte,Max Planck SocietyUsing innovative computer programs and biochemical experiments, researchers identified and quantified fragments that the cellular garbage dispo
Medicare doesn't cover obesity drugs, but 76% of older adults think it should: Poll

Medicare doesn't cover obesity drugs, but 76% of older adults think it should: Poll

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainThe vast majority of older adults—83%—think health insurers should cover medications that can help people with obesity manage their weigh

Medicare doesn't cover obesity drugs, but 76% of older adults think it should: Poll

byUniversity of MichiganCredit: Pixabay/CC0 Public DomainThe vast majority of older adults—83%—think health insurers should cover medications that can help people with obesity manage their weigh
Erections: What researchers learned from mice could help with sexual health in humans

Erections: What researchers learned from mice could help with sexual health in humans

FEBRUARY 9, 2024 Editors' notesby Christian Göritz,The ConversationFibroblasts mediate erectile activity–dependent modulation of penile blood flow. Credit:Science(2024). DOI: 10.

Erections: What researchers learned from mice could help with sexual health in humans

FEBRUARY 9, 2024 Editors' notesby Christian Göritz,The ConversationFibroblasts mediate erectile activity–dependent modulation of penile blood flow. Credit:Science(2024). DOI: 10.
Examining the potential of the common bovine as a potential therapeutic research model

Examining the potential of the common bovine as a potential therapeutic research model

by Tom Fleischman,Cornell UniversityGraphical Abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108886Research involving animal models—for purposes such as developing new vac

Examining the potential of the common bovine as a potential therapeutic research model

by Tom Fleischman,Cornell UniversityGraphical Abstract. Credit:iScience(2024). DOI: 10.1016/j.isci.2024.108886Research involving animal models—for purposes such as developing new vac
Perfecting 3D-printed blood vessels with pores

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman

Perfecting 3D-printed blood vessels with pores

JANUARY 17, 2024byPohang University of Science and TechnologyFabrication process of S-SDVs and the results of HUVECs migration through pores. Credit: POSTECHDue to the substantial clinical deman
Alcohol may help flush out arsenic from the body, study finds

Alcohol may help flush out arsenic from the body, study finds

by Nanjing Institute of Environmental SciencesGraphical abstract. Credit: Eco-Environment & HealthAstudypublished inEco-Environment & Healthsheds light on the complex i

Alcohol may help flush out arsenic from the body, study finds

by Nanjing Institute of Environmental SciencesGraphical abstract. Credit: Eco-Environment & HealthAstudypublished inEco-Environment & Healthsheds light on the complex i
ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r

ABT199/Venetoclax synergism with thiotepa in acute myeloid leukemia (AML) cells

by Impact Journals LLCEffects of various drug combinations on molecular markers of apoptosis in patient-derived cell samples. Credit:Oncotarget(2024). DOI: 10.18632/oncotarget.28563A new r
Protein production glitches in Huntington's disease revealed

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe

Protein production glitches in Huntington's disease revealed

by Shafaq Zia,Whitehead Institute for Biomedical ResearchRNAs with expanded CAG repeats (red) form regions of high concentration in the nucleus (blue) of a cell. Credit: Rachel Anderson/ Whitehe
FDA Approves Lymphir: A New Hope for CTCL Patients

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.

FDA Approves Lymphir: A New Hope for CTCL Patients

The U.S. Food and Drug Administration (FDA) had approved Lymphir (denileukin diftitox-cxdl), a novel immunotherapy for the treatment of relapsed or refractory cutaneous T-cell lymphoma (CTCL) after at least one prior systemic therapy.
Researchers are using RNA in a new approach to fight HIV

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur

Researchers are using RNA in a new approach to fight HIV

FEBRUARY 20, 2024byUniversity of WaterlooGraphical abstract. Credit:Journal of Controlled Release(2024). DOI: 10.1016/j.jconrel.2023.12.043Society learned about the value of mRNA dur