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Allergy&Clinical immunology
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High stakes of early immune development revealed—and a potential probiotic fix

High stakes of early immune development revealed—and a potential probiotic fix

byThe Scripps Research InstituteThe study found that antibiotic use in early life can reduce the number of healthy gut bacteria required to support immune system development. However, administering pr

High stakes of early immune development revealed—and a potential probiotic fix

byThe Scripps Research InstituteThe study found that antibiotic use in early life can reduce the number of healthy gut bacteria required to support immune system development. However, administering pr
Evaluating the impact of heat-inactivated bacteria on age-related inflammation

Evaluating the impact of heat-inactivated bacteria on age-related inflammation

byShinshu UniversityHeat-killed L. kefiri YRC2606 attenuates immunosenescence by suppressing IL-6/STAT3 signaling and alleviating thymic atrophy, thereby reducing inflammatory cytokine production and

Evaluating the impact of heat-inactivated bacteria on age-related inflammation

byShinshu UniversityHeat-killed L. kefiri YRC2606 attenuates immunosenescence by suppressing IL-6/STAT3 signaling and alleviating thymic atrophy, thereby reducing inflammatory cytokine production and
Eczema injectable drug provides quick itch relief, clinical trial results show

Eczema injectable drug provides quick itch relief, clinical trial results show

by Dennis ThompsonA recently approved injectable eczema drug provides quick itch relief to patients with the maddening skin disease, a new study says.Nemolizumab(Nemluvio) relieved itchiness within tw

Eczema injectable drug provides quick itch relief, clinical trial results show

by Dennis ThompsonA recently approved injectable eczema drug provides quick itch relief to patients with the maddening skin disease, a new study says.Nemolizumab(Nemluvio) relieved itchiness within tw
Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

byPerelman School of Medicine at the University of PennsylvaniaCredit:Cell(2025). DOI: 10.1016/j.cell.2025.11.023mRNA vaccines, such as those used against COVID-19, are effective at generating antibod

Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses

byPerelman School of Medicine at the University of PennsylvaniaCredit:Cell(2025). DOI: 10.1016/j.cell.2025.11.023mRNA vaccines, such as those used against COVID-19, are effective at generating antibod
Building a better vaccine: Flu antibodies show expanded role in preventing transmission

Building a better vaccine: Flu antibodies show expanded role in preventing transmission

by Kim North Shine,University of MichiganFactors influencing pairwise transmission risk, as tested across the different models used in the study. Credit:Nature Communications(2025). DOI: 10.1038/s4146

Building a better vaccine: Flu antibodies show expanded role in preventing transmission

by Kim North Shine,University of MichiganFactors influencing pairwise transmission risk, as tested across the different models used in the study. Credit:Nature Communications(2025). DOI: 10.1038/s4146
AI that predicts sequences within antibodies could lead to new therapeutic treatments

AI that predicts sequences within antibodies could lead to new therapeutic treatments

byUniversity of SurreyImmunoMatch for predicting cognate antibody chain pairing. Credit:Nature Methods(2025). DOI: 10.1038/s41592-025-02913-xA new artificial intelligence model could help design antib

AI that predicts sequences within antibodies could lead to new therapeutic treatments

byUniversity of SurreyImmunoMatch for predicting cognate antibody chain pairing. Credit:Nature Methods(2025). DOI: 10.1038/s41592-025-02913-xA new artificial intelligence model could help design antib
New immune-probing technique maps regulatory T cell interactions

New immune-probing technique maps regulatory T cell interactions

byOsaka University(a) Effector Tregs (eTregs) most strongly affect CD8-EM cells and B-plasma cells. (b) A closer look reveals eTregs control CD8-EM cells by stopping their division and reducing

New immune-probing technique maps regulatory T cell interactions

byOsaka University(a) Effector Tregs (eTregs) most strongly affect CD8-EM cells and B-plasma cells. (b) A closer look reveals eTregs control CD8-EM cells by stopping their division and reducing