Genetic variants involved in rapid immune response linked to earlier breast cancer onset in BRCA1 carriers

byBritish Medical JournalCredit: CC0 Public DomainDamaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers o

Updated on: May 24,2026

Genetic variants involved in rapid immune response linked to earlier breast cancer onset in BRCA1 carriers

byBritish Medical JournalCredit: CC0 Public DomainDamaging variants in genes involved in a rapid immune response (innate immunity) are significantly linked to earlier breast cancer onset in carriers o

Updated on:May 24,2026

A new immunotherapy target? How SRC-3 in Tregs may reshape solid-tumor treatment

by Ana María Rodríguez,Baylor College of MedicineThe loss of SRC-3 in Treg leads to immune suppression of glioblastoma in mice: (A) Experimental design for the orthotopic injection of glioblastoma cel

Updated on: May 23,2026

A new immunotherapy target? How SRC-3 in Tregs may reshape solid-tumor treatment

by Ana María Rodríguez,Baylor College of MedicineThe loss of SRC-3 in Treg leads to immune suppression of glioblastoma in mice: (A) Experimental design for the orthotopic injection of glioblastoma cel

Updated on:May 23,2026

An avatar to study pediatric brain cancer may soon be a reality

byUniversity of TrentoA summary of pPDT and pPDXT generation, amplification and biobanking and their use in drug screening and other applications. Credit:Nature Protocols(2026). DOI: 10.1038/s41596-02

Updated on: May 22,2026

An avatar to study pediatric brain cancer may soon be a reality

byUniversity of TrentoA summary of pPDT and pPDXT generation, amplification and biobanking and their use in drug screening and other applications. Credit:Nature Protocols(2026). DOI: 10.1038/s41596-02

Updated on:May 22,2026

uPAR-targeted CAR T cells shrank solid tumors and cleared metastases in mice

byMemorial Sloan Kettering Cancer CenterCredit:Cell(2026). DOI: 10.1016/j.cell.2026.03.002Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers li

Updated on: May 20,2026

uPAR-targeted CAR T cells shrank solid tumors and cleared metastases in mice

byMemorial Sloan Kettering Cancer CenterCredit:Cell(2026). DOI: 10.1016/j.cell.2026.03.002Chimeric antigen receptor T-cell therapy—CAR T for short—has been a major advance in treating blood cancers li

Updated on:May 20,2026

TYK2 protein suppresses breast cancer metastasis by sensing extracellular stiffness, research finds

by Miles Martin,University of California - San DiegoIn healthy tissues, seen in the top two panels here, TYK2 (green) is found on the cell membrane and colocalizes with E-cadherin (red), a protein tha

Updated on: May 19,2026

TYK2 protein suppresses breast cancer metastasis by sensing extracellular stiffness, research finds

by Miles Martin,University of California - San DiegoIn healthy tissues, seen in the top two panels here, TYK2 (green) is found on the cell membrane and colocalizes with E-cadherin (red), a protein tha

Updated on:May 19,2026

After allogeneic transplant, VIC-1911 regimen shows low severe GVHD and no relapse

byRoswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResults of a Phase I clinical trial show that patients who undergo a blood stem cell transplant involving a donor have a low

Updated on: May 19,2026

After allogeneic transplant, VIC-1911 regimen shows low severe GVHD and no relapse

byRoswell Park Comprehensive Cancer CenterCredit: Unsplash/CC0 Public DomainResults of a Phase I clinical trial show that patients who undergo a blood stem cell transplant involving a donor have a low

Updated on:May 19,2026

New analytical method reveals how drug combinations act in leukemia

byTampere UniversityCoPISA workflow and possible states for target discovery in combinatorial therapy. Credit:Nature Communications(2026). DOI: 10.1038/s41467-026-70394-3Acute myeloid leukemia (AML) r

Updated on: May 15,2026

New analytical method reveals how drug combinations act in leukemia

byTampere UniversityCoPISA workflow and possible states for target discovery in combinatorial therapy. Credit:Nature Communications(2026). DOI: 10.1038/s41467-026-70394-3Acute myeloid leukemia (AML) r

Updated on:May 15,2026

MetaRing quickly identifies breast cancer drug sensitivity

by Hefei Institutes of Physical Science, Chinese Academy of SciencesSchematic illustration of the MetaRing platform for detecting paclitaxel treatment sensitivity in breast cancer. Credit: HUANG Guang

Updated on: April 27,2026

MetaRing quickly identifies breast cancer drug sensitivity

by Hefei Institutes of Physical Science, Chinese Academy of SciencesSchematic illustration of the MetaRing platform for detecting paclitaxel treatment sensitivity in breast cancer. Credit: HUANG Guang

Updated on:April 27,2026

FDA warns biotech firm over cancer drug claims

by HealthDay StaffThe U.S. Food and Drug Administration (FDA) has warned a biotech company about claims that its bladder cancer drug could treat and prevent multiple types of cancer.The agency sent a

Updated on: April 22,2026

FDA warns biotech firm over cancer drug claims

by HealthDay StaffThe U.S. Food and Drug Administration (FDA) has warned a biotech company about claims that its bladder cancer drug could treat and prevent multiple types of cancer.The agency sent a

Updated on:April 22,2026

DOCK10 emerges as key trigger of dangerous insulin hypersecretion in rare pancreatic tumors

byInstitute of Science TokyoThe dedicator of cytokinesis 10 (DOCK10) gene has been identified as a key driver of abnormal insulin secretion in insulinomas, as reported by researchers from Institute of

Updated on: April 16,2026

DOCK10 emerges as key trigger of dangerous insulin hypersecretion in rare pancreatic tumors

byInstitute of Science TokyoThe dedicator of cytokinesis 10 (DOCK10) gene has been identified as a key driver of abnormal insulin secretion in insulinomas, as reported by researchers from Institute of

Updated on:April 16,2026

3 million-cell map shows menopause reshapes breast tissue, possibly raising cancer risk

byUniversity of CambridgeCredit: RDNE Stock project from PexelsScientists have created the most detailed map to date, comprised of over 3 million cells, showing how breast tissue changes as women age—

Updated on: April 11,2026

3 million-cell map shows menopause reshapes breast tissue, possibly raising cancer risk

byUniversity of CambridgeCredit: RDNE Stock project from PexelsScientists have created the most detailed map to date, comprised of over 3 million cells, showing how breast tissue changes as women age—

Updated on:April 11,2026

Study of 11,000 tumors maps 134 DNA damage signatures across 16 cancers

byUniversity of ManchesterRelationship between SBS, DBS, ID, CN and SV signatures across cancers. Credit:Nature Genetics(2026). DOI: 10.1038/s41588-025-02474-xA team of cancer genomics scientists from

Updated on: April 09,2026

Study of 11,000 tumors maps 134 DNA damage signatures across 16 cancers

byUniversity of ManchesterRelationship between SBS, DBS, ID, CN and SV signatures across cancers. Credit:Nature Genetics(2026). DOI: 10.1038/s41588-025-02474-xA team of cancer genomics scientists from

Updated on:April 09,2026