The roles of genes and 3D genome folds in determining health

by Carmen Rotte,Max Planck SocietyModel for the mechanism of chromatin domain formation in S. cerevisiae. Credit:Nature Genetics(2024). DOI:10.1038/s41588-023-01649-8Whether we stay

Updated on: March 13,2024

The roles of genes and 3D genome folds in determining health

by Carmen Rotte,Max Planck SocietyModel for the mechanism of chromatin domain formation in S. cerevisiae. Credit:Nature Genetics(2024). DOI:10.1038/s41588-023-01649-8Whether we stay

Updated on:March 13,2024

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

Updated on: March 30,2024

The dual role of well-known protein sheds light on Parkinson's disease mechanisms

NOVEMBER 6, 2023by Lisbeth Heilesen,Aarhus UniversityNew research from Aarhus University with international collaborations has revealed that natural aSN activates an important calcium pump in th

Updated on:March 30,2024

How aging affects stem cells: A fly's tale

byRIKENExcessive cell proliferation (left) and stem cell exhaustion (right) during aging. Credit: RIKENScientists from the RIKEN Center for Biosystems Dynamics Research (BDR) have identified key

Updated on: September 25,2024

How aging affects stem cells: A fly's tale

byRIKENExcessive cell proliferation (left) and stem cell exhaustion (right) during aging. Credit: RIKENScientists from the RIKEN Center for Biosystems Dynamics Research (BDR) have identified key

Updated on:September 25,2024

Researchers uncover news clues about the cause of craniofacial birth defects

byUniversity of Wisconsin-MadisonThis image of a section through the midface of a mouse embryo illustrates fusion of the tissues that form the secondary palate above the tongue. Green staining i

Updated on: March 30,2024

Researchers uncover news clues about the cause of craniofacial birth defects

byUniversity of Wisconsin-MadisonThis image of a section through the midface of a mouse embryo illustrates fusion of the tissues that form the secondary palate above the tongue. Green staining i

Updated on:March 30,2024

Systematic review links outdoor air pollution to differences in children's brains

by Alex Russell,UC DavisCredit: Pixabay/CC0 Public DomainOutdoor air pollution from power plants, fires and cars continues to degrade human, animal and environmental health around the globe. New

Updated on: October 17,2024

Systematic review links outdoor air pollution to differences in children's brains

by Alex Russell,UC DavisCredit: Pixabay/CC0 Public DomainOutdoor air pollution from power plants, fires and cars continues to degrade human, animal and environmental health around the globe. New

Updated on:October 17,2024

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on: March 13,2024

Researcher identifies key mechanism in Parkinson's disease

by Anna Zarra Aldrich,University of ConnecticutProper regulation of LRRK2 levels is important for Parkinson's disease (PD). ATIC, a purine biosynthesis pathway enzyme, and its substrate prec

Updated on:March 13,2024

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on: April 28,2024

Scientists uncover key resistance mechanism to Wnt inhibitors in pancreatic and colorectal cancers

byDuke-NUS Medical SchoolDuke-NUS scientists show that FBXW7-mutant cancers are resistant to Wnt inhibitors by comparing the impact Wnt inhibitor ETC-159 has on cancer cells with and without FBX

Updated on:April 28,2024

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death

Updated on: March 14,2024

CRISPR and other new technologies open doors for drug development, but which diseases get prioritized?

DECEMBER 14, 2023 Editors' notesby C. Michael White,The ConversationCredit: Pixabay/CC0 Public DomainPrescription drugs and vaccines revolutionized health care, dramatically decreasing death

Updated on:March 14,2024

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Updated on: March 13,2024

Researchers uncover 'circular logic' of RNAs in Parkinson's disease

byBrigham and Women's HospitalScherzer and colleagues laser-captured neurons from 190 frozen postmortem human brain samples, including some non-neuronal cells for comparison. Then, they used

Updated on:March 13,2024

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan

Updated on: March 13,2024

Researchers uncover genetic factors for severe Lassa fever

by Allessandra DiCorato,Broad Institute of MIT and HarvardScanning electron image of the Lassa virus budding off a cell. Credit: NIAID Integrated Research Facility (IRF) in Fort Detrick, Marylan

Updated on:March 13,2024

Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr

Updated on: March 15,2024

Analysis of research grants pipeline illustrates systematic disadvantages

FEBRUARY 21, 2024by Roger Anderson,Northwestern UniversityRate of K99 and R00 awards and conversion by year. Credit:eLife(2024). DOI: 10.7554/eLife.88984.4Of the more than 3,000 extr

Updated on:March 15,2024

New resource maps gene-disease links across common conditions, paving the way for personalized medicine

byHebrew University of JerusalemCredit: Pixabay/CC0 Public DomainA new study introduces an innovative tool for exploring gene-disease connections: the PWAS Hub. This resource is based on the nov

Updated on: November 22,2024

New resource maps gene-disease links across common conditions, paving the way for personalized medicine

byHebrew University of JerusalemCredit: Pixabay/CC0 Public DomainA new study introduces an innovative tool for exploring gene-disease connections: the PWAS Hub. This resource is based on the nov

Updated on:November 22,2024