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Precursor of cholesterol protects cells from ferroptosis, study finds

Precursor of cholesterol protects cells from ferroptosis, study finds

JANUARY 31, 2024byUniversity of WürzburgSpace-filling model of the Cholesterol molecule. Credit: RedAndr/WikipediaIn a groundbreaking study, a team led by Würzburg Professor José Pedro Friedmann

Precursor of cholesterol protects cells from ferroptosis, study finds

JANUARY 31, 2024byUniversity of WürzburgSpace-filling model of the Cholesterol molecule. Credit: RedAndr/WikipediaIn a groundbreaking study, a team led by Würzburg Professor José Pedro Friedmann
UK issues guidelines for use of stem cell-based embryo models in research

UK issues guidelines for use of stem cell-based embryo models in research

byUniversity of CambridgeThese models can be created in the lab and mimic aspects of early human embryo development, which raises various ethical considerations. Credit: Irene Zorzan and Teresa

UK issues guidelines for use of stem cell-based embryo models in research

byUniversity of CambridgeThese models can be created in the lab and mimic aspects of early human embryo development, which raises various ethical considerations. Credit: Irene Zorzan and Teresa
Scientists say outdated diabetes drug still has something to offer

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil

Scientists say outdated diabetes drug still has something to offer

byUniversity of California - San DiegoThis micrograph shows a single macrophage, which is a type of cell in the immune system. In obesity-related inflammation, large numbers of these cells infil
Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

by Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging ResearchCredit: CC0 Public DomainA newViewpoint articlepublished in theJournal of the American Medical Association&nb

Class of Alzheimer's drug presents unique challenge for patients with cardiovascular disease

by Hebrew SeniorLife Hinda and Arthur Marcus Institute for Aging ResearchCredit: CC0 Public DomainA newViewpoint articlepublished in theJournal of the American Medical Association&nb
Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N

Researchers describe tools to better understand CaMKII, a protein involved in brain and heart disease

by CU Anschutz Medical CampusOptogenetic tools for monitoring and controlling CaMKII activation(A) Camui is a FRET-based sensor that detects conformational changes in CaMKII upon activation. An N
New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r

New approach to the design of therapies that enhance the effect of cholesterol-lowering drugs

FEBRUARY 1, 2024by Centro Nacional de Investigaciones Cardiovasculares Carlos III (F.S.P.)Graphical summary. Credit:Nature Cardiovascular Research(2024). DOI: 10.1038/s44161-023-00412-wA r
Research suggests chronic pain is different for males and females

Research suggests chronic pain is different for males and females

JANUARY 24, 2024by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainA University of Alberta research team has uncovered differences in the way male and female mice develo

Research suggests chronic pain is different for males and females

JANUARY 24, 2024by Gillian Rutherford,University of AlbertaCredit: Pixabay/CC0 Public DomainA University of Alberta research team has uncovered differences in the way male and female mice develo
New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

byThe Mount Sinai HospitalKiNet functionalities. Credit:npj Systems Biology and Applications(2024). DOI: 10.1038/s41540-024-00442-5Researchers from the Icahn School of Medicine at Mo

New web portal empowers drug discovery, systems-level analysis of critical kinase-substrate interactions

byThe Mount Sinai HospitalKiNet functionalities. Credit:npj Systems Biology and Applications(2024). DOI: 10.1038/s41540-024-00442-5Researchers from the Icahn School of Medicine at Mo
New findings suggest life span can be increased by making cells less efficient at producing energy

New findings suggest life span can be increased by making cells less efficient at producing energy

by Pennington Biomedical Research CenterChristopher Axelrod, Director, Integrated Physiology and Molecular Medicine Laboratory at Pennington Biomedical Research Center. Credit: PBRCA newstudy&nb

New findings suggest life span can be increased by making cells less efficient at producing energy

by Pennington Biomedical Research CenterChristopher Axelrod, Director, Integrated Physiology and Molecular Medicine Laboratory at Pennington Biomedical Research Center. Credit: PBRCA newstudy&nb
Music and genomes: Beethoven's genes put to the test

Music and genomes: Beethoven's genes put to the test

by Ina Wittmann,Max Planck SocietyThe analysis of Beethoven's DNA shows possibilities and limits of predictions in the field of genetics. Credit: MPIEA / F. BernoullyTo what extent are excep

Music and genomes: Beethoven's genes put to the test

by Ina Wittmann,Max Planck SocietyThe analysis of Beethoven's DNA shows possibilities and limits of predictions in the field of genetics. Credit: MPIEA / F. BernoullyTo what extent are excep
Imetelstat leads to durable red blood cell transfusion independence

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi

Imetelstat leads to durable red blood cell transfusion independence

by Elana GotkineFor heavily transfused patients with lower-risk myelodysplastic syndromes (LR-MDS) who are not responding to or are ineligible for erythropoiesis-stimulating agents (ESAs), the competi