Drug-drug interactions seen in 21.4% of children with medication exposure

by Elana GotkineMore than 20% of children with two or more medication exposures experience major drug-drug interactions (DDIs) annually, according to a study published online Jan. 4 inPediatrics

Updated on: January 26,2024

Drug-drug interactions seen in 21.4% of children with medication exposure

by Elana GotkineMore than 20% of children with two or more medication exposures experience major drug-drug interactions (DDIs) annually, according to a study published online Jan. 4 inPediatrics

Updated on:January 26,2024

First clinical trial of vosoritide for children with hypochondroplasia shows increased growth

byChildren's National HospitalStanding height SDS. Credit:eClinicalMedicine(2024). DOI: 10.1016/j.eclinm.2024.102591Vosoritide's first global Phase II study showed an average

Updated on: April 28,2024

First clinical trial of vosoritide for children with hypochondroplasia shows increased growth

byChildren's National HospitalStanding height SDS. Credit:eClinicalMedicine(2024). DOI: 10.1016/j.eclinm.2024.102591Vosoritide's first global Phase II study showed an average

Updated on:April 28,2024

Antibiotics use in relation to colorectal cancer risk, survival and postoperative complications

by Claes Björnberg,Umea UniversityCredit: Pixabay/CC0 Public DomainThe bacteria in our gut are believed to be involved in cancer of the large bowel. Exposure to antibiotics, which can affect gut

Updated on: March 28,2024

Antibiotics use in relation to colorectal cancer risk, survival and postoperative complications

by Claes Björnberg,Umea UniversityCredit: Pixabay/CC0 Public DomainThe bacteria in our gut are believed to be involved in cancer of the large bowel. Exposure to antibiotics, which can affect gut

Updated on:March 28,2024

AI-supported image analysis: How metrics determine quality

FEBRUARY 12, 2024byGerman Cancer Research CenterP1: Pitfalls related to the inadequate choice of the problem category. The effect of using segmentation metrics for object-detection problems. The

Updated on: March 25,2024

AI-supported image analysis: How metrics determine quality

FEBRUARY 12, 2024byGerman Cancer Research CenterP1: Pitfalls related to the inadequate choice of the problem category. The effect of using segmentation metrics for object-detection problems. The

Updated on:March 25,2024

Hyperoxidized PRDX3: A Novel Biomarker for Ferroptosis in Alcoholic and Non-Alcoholic Fatty Liver Diseases

Updated on: October 02,2024

Hyperoxidized PRDX3: A Novel Biomarker for Ferroptosis in Alcoholic and Non-Alcoholic Fatty Liver Diseases

Updated on:October 02,2024

Understanding molecular drivers of lymphedema

by Olivia Dimmer,Northwestern UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI176577Northwestern Medicine scientists have uncovered molecular mechanisms und

Updated on: July 23,2024

Understanding molecular drivers of lymphedema

by Olivia Dimmer,Northwestern UniversityCredit:Journal of Clinical Investigation(2024). DOI: 10.1172/JCI176577Northwestern Medicine scientists have uncovered molecular mechanisms und

Updated on:July 23,2024

Sex hormone-driven MBOAT1/2 expression in ferroptosis surveillance

Updated on: September 13,2024

Sex hormone-driven MBOAT1/2 expression in ferroptosis surveillance

Updated on:September 13,2024

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on: July 23,2024

Recommendations to facilitate design and implementation of clinical pharmacogenomic DPYD genotyping assays

by Association for Molecular PathologyCredit: Pixabay/CC0 Public DomainThe Association for Molecular Pathology (AMP) has published consensus recommendations to aid in the design and validation of clin

Updated on:July 23,2024

Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model

by Impact Journals LLCGene expression profiling revealed various patterns of changes in PFC and hippocampus of P301S mice at different ages. Credit:Aging(2023). DOI: 10.18632/aging.205057A

Updated on: January 10,2024

Longitudinal characterization of behavioral, morphological and transcriptomic changes in a tauopathy mouse model

by Impact Journals LLCGene expression profiling revealed various patterns of changes in PFC and hippocampus of P301S mice at different ages. Credit:Aging(2023). DOI: 10.18632/aging.205057A

Updated on:January 10,2024

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also

Updated on: April 27,2024

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also

Updated on:April 27,2024

Color-adjusting technique for histopathology image datasets could help empower machine-learning-based diagnostic tools

bySPIETissue image datasets processed by stained SAN (bottom row) achieve color distributions that are more consistent than those processed using other techniques. Such consistency is essential

Updated on: September 04,2024

Color-adjusting technique for histopathology image datasets could help empower machine-learning-based diagnostic tools

bySPIETissue image datasets processed by stained SAN (bottom row) achieve color distributions that are more consistent than those processed using other techniques. Such consistency is essential

Updated on:September 04,2024

SGLT-2 inhibitors show mixed results after heart attack

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainWhile the composite of death and heart failure hospitalizations was not significantly reduced, empagliflozin may help reduce hea

Updated on: April 28,2024

SGLT-2 inhibitors show mixed results after heart attack

byAmerican College of CardiologyCredit: Unsplash/CC0 Public DomainWhile the composite of death and heart failure hospitalizations was not significantly reduced, empagliflozin may help reduce hea

Updated on:April 28,2024