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Breakthroughs
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Drug found to extend survival in prostate cancer with genetic mutations

Drug found to extend survival in prostate cancer with genetic mutations

by Melissa Rohman,Northwestern University(A) rPFS for patients with a germline BRCA alteration, (B) rPFS for patients with a somatic BRCA alteration, (C) OS for patients with a germline BRCA alt

Drug found to extend survival in prostate cancer with genetic mutations

by Melissa Rohman,Northwestern University(A) rPFS for patients with a germline BRCA alteration, (B) rPFS for patients with a somatic BRCA alteration, (C) OS for patients with a germline BRCA alt
Pharmacologic restraint used in 3 percent of pediatric mental health admissions

Pharmacologic restraint used in 3 percent of pediatric mental health admissions

by Elana GotkineThe use of pharmacologic restraints occurs in 3 percent of hospitalizations for children admitted with a primary mental health diagnosis, according to a study published online Dec. 11

Pharmacologic restraint used in 3 percent of pediatric mental health admissions

by Elana GotkineThe use of pharmacologic restraints occurs in 3 percent of hospitalizations for children admitted with a primary mental health diagnosis, according to a study published online Dec. 11
Gene therapy gets a turbo boost from researchers

Gene therapy gets a turbo boost from researchers

byUniversity of Hawaii at ManoaGraphical abstract. Credit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae534For decades, scientists have dreamed of a future where genetic disease

Gene therapy gets a turbo boost from researchers

byUniversity of Hawaii at ManoaGraphical abstract. Credit:Nucleic Acids Research(2024). DOI: 10.1093/nar/gkae534For decades, scientists have dreamed of a future where genetic disease
Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv

Circuit-specific gene therapy brings new hope for treatment of Parkinson's disease

byChinese Academy of SciencesRetrograde AAV selectively targets D1-MSNs and rescues parkinsonian symptoms with chemogenetic modulation. Credit: SIATResearchers from the Shenzhen Institute of Adv
Blast exposure linked to intestinal problems

Blast exposure linked to intestinal problems

by Veterans Affairs Research CommunicationsCredit: Unsplash/CC0 Public DomainA study by New York and Rocky Mountain U.S. Department of Veterans Affairs researchers showed blast exposure can cause inte

Blast exposure linked to intestinal problems

by Veterans Affairs Research CommunicationsCredit: Unsplash/CC0 Public DomainA study by New York and Rocky Mountain U.S. Department of Veterans Affairs researchers showed blast exposure can cause inte
Study identifies factors that affect antibiotic prescribing for acne

Study identifies factors that affect antibiotic prescribing for acne

by Elana GotkineMultiple salient factors affect long-term antibiotic prescribing practices for acne, according to a studypublishedinJAMA Dermatology.Ronnie A. Festok, from the Emory

Study identifies factors that affect antibiotic prescribing for acne

by Elana GotkineMultiple salient factors affect long-term antibiotic prescribing practices for acne, according to a studypublishedinJAMA Dermatology.Ronnie A. Festok, from the Emory
Oleic acid: A potential therapy for people with a rare genetic condition

Oleic acid: A potential therapy for people with a rare genetic condition

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainA mutation in a protein regulating natural killer (NK) cells' function is at the root of immune deficiency in some peo

Oleic acid: A potential therapy for people with a rare genetic condition

byUniversity of California, Los AngelesCredit: Pixabay/CC0 Public DomainA mutation in a protein regulating natural killer (NK) cells' function is at the root of immune deficiency in some peo
Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

by Impact Journals LLCAGE enhances endothelial relaxation in aorta rings. (A) Representative traces under specified conditions. (B) Percentage of relaxation proportional to Ach concentration. (C) Maxi

Medicinal herb found to inhibit acetylation of eNOS in vascular dysfunction

by Impact Journals LLCAGE enhances endothelial relaxation in aorta rings. (A) Representative traces under specified conditions. (B) Percentage of relaxation proportional to Ach concentration. (C) Maxi
New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought

New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought

by Allessandra DiCorato,Broad Institute of MIT and HarvardCytokine production map by cell type. Credit:Nature(2023). DOI: 10.1038/s41586-023-06816-9The immune system can carry out ma

New 'dictionary' of immune responses reveals far more complexity in the immune system than previously thought

by Allessandra DiCorato,Broad Institute of MIT and HarvardCytokine production map by cell type. Credit:Nature(2023). DOI: 10.1038/s41586-023-06816-9The immune system can carry out ma
Researchers help design easy-to-open, child-resistant medicine bottle

Researchers help design easy-to-open, child-resistant medicine bottle

by Abby Robinson,Georgia Institute of TechnologyEquipment used by Georgia Tech Research Institute (GTRI) product design researchers measures the forces required to open prescription medicine con

Researchers help design easy-to-open, child-resistant medicine bottle

by Abby Robinson,Georgia Institute of TechnologyEquipment used by Georgia Tech Research Institute (GTRI) product design researchers measures the forces required to open prescription medicine con
How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also

How the body switches out of 'fight' mode: Study shows hormones reprogram metabolism of immune cells

byCharité - Universitätsmedizin BerlinA macrophage activated by an inflammatory stimulus after being treated with cortisone. Cortisone affects not only the genes in the nucleus (blue), but also