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Treating tuberculosis when antibiotics no longer work

Treating tuberculosis when antibiotics no longer work

byUniversity of CologneCredit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2023.12.007Researchers have identified new antibiotic molecules that target Mycobacterium tuberculo

Treating tuberculosis when antibiotics no longer work

byUniversity of CologneCredit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2023.12.007Researchers have identified new antibiotic molecules that target Mycobacterium tuberculo
Scientists develop an agent capable of selectively inhibiting the body's stress response

Scientists develop an agent capable of selectively inhibiting the body's stress response

JANUARY 22, 2024by Daniel Meierhans,ETH ZurichThe DEGs we identified upon 2 h, and 18 h of DEX treatments in A549 cells align with the other existing RNAseq and ChIP-seq datasets. Credit:N

Scientists develop an agent capable of selectively inhibiting the body's stress response

JANUARY 22, 2024by Daniel Meierhans,ETH ZurichThe DEGs we identified upon 2 h, and 18 h of DEX treatments in A549 cells align with the other existing RNAseq and ChIP-seq datasets. Credit:N
Spot-on laser treatment for skin blemishes becoming clearer with new index

Spot-on laser treatment for skin blemishes becoming clearer with new index

by Osaka Metropolitan UniversityLeft: Unirradiated melanosomes show a smooth surface. Right: Irradiation by picosecond lasers with a pulse width of 450 ps at a wavelength of 1,064 nm and a fluenc

Spot-on laser treatment for skin blemishes becoming clearer with new index

by Osaka Metropolitan UniversityLeft: Unirradiated melanosomes show a smooth surface. Right: Irradiation by picosecond lasers with a pulse width of 450 ps at a wavelength of 1,064 nm and a fluenc
Aspirin cuts liver fat in clinical trial

Aspirin cuts liver fat in clinical trial

by Tracy Hampton,Harvard UniversityCredit: Pixabay/CC0 Public DomainThe most common chronic liver disease—metabolic dysfunction–associated steatotic liver disease (MASLD)—is characterized by an

Aspirin cuts liver fat in clinical trial

by Tracy Hampton,Harvard UniversityCredit: Pixabay/CC0 Public DomainThe most common chronic liver disease—metabolic dysfunction–associated steatotic liver disease (MASLD)—is characterized by an
Calcium channel blockers key to reversing myotonic dystrophy muscle weakness, study finds

Calcium channel blockers key to reversing myotonic dystrophy muscle weakness, study finds

byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainNew research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy

Calcium channel blockers key to reversing myotonic dystrophy muscle weakness, study finds

byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainNew research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy
Scientists improve the equation in FDA guidance predicting drug interactions

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und

Scientists improve the equation in FDA guidance predicting drug interactions

by Institute for Basic ScienceThe new equation provides more accurate predictions than the conventional FDA equation. The FDA equation with Fg estimated assuming Fa = 1 underpredicts the area und
Super permeable wearable electronics developed for stable, long-term biosignal monitoring

Super permeable wearable electronics developed for stable, long-term biosignal monitoring

by Michael Gibb,City University of Hong KongThe permeable wearable electronics developed by the team for long-term biosignal monitoring. Credit: City University of Hong KongSuper wearable electr

Super permeable wearable electronics developed for stable, long-term biosignal monitoring

by Michael Gibb,City University of Hong KongThe permeable wearable electronics developed by the team for long-term biosignal monitoring. Credit: City University of Hong KongSuper wearable electr
Demystifying a key receptor in substance use and neuropsychiatric disorders

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine

Demystifying a key receptor in substance use and neuropsychiatric disorders

byThe Mount Sinai HospitalMount Sinai Icahn scientists took detailed pictures of how drugs can bind to the TAAR1 receptor using CryoEM. They also discovered that an antipsychotic drug, asenapine
New frontier in biomedical engineering: Protein coacervates engineered into adhesive for unprecedented skin repair speed

New frontier in biomedical engineering: Protein coacervates engineered into adhesive for unprecedented skin repair speed

by Engineering(a) Schematic diagram of ECM composition. Elastin and growth factor are important components of the ECM. (b) Construction and expression of the protein. (c) Preparation of the EED adhesi

New frontier in biomedical engineering: Protein coacervates engineered into adhesive for unprecedented skin repair speed

by Engineering(a) Schematic diagram of ECM composition. Elastin and growth factor are important components of the ECM. (b) Construction and expression of the protein. (c) Preparation of the EED adhesi
Liver fibrosis 'off switch' discovered in mice

Liver fibrosis 'off switch' discovered in mice

by University of California - San DiegoCredit: CC0 Public DomainChronic alcohol abuse and hepatitis can injure the liver, often leading to a buildup of collagen and scar tissue. Understanding thi

Liver fibrosis 'off switch' discovered in mice

by University of California - San DiegoCredit: CC0 Public DomainChronic alcohol abuse and hepatitis can injure the liver, often leading to a buildup of collagen and scar tissue. Understanding thi
Experts release the latest guide for systematic reviews of preclinical research

Experts release the latest guide for systematic reviews of preclinical research

byRadboud UniversityCredit: Unsplash/CC0 Public DomainA new publication inNature Reviews Methods Primersprovides essential guidance for conducting rigorous systematic reviews on stud

Experts release the latest guide for systematic reviews of preclinical research

byRadboud UniversityCredit: Unsplash/CC0 Public DomainA new publication inNature Reviews Methods Primersprovides essential guidance for conducting rigorous systematic reviews on stud