Calcium channel blockers key to reversing myotonic dystrophy muscle weakness, study finds

byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainNew research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy

Updated on: January 26,2024

Calcium channel blockers key to reversing myotonic dystrophy muscle weakness, study finds

byUniversity of Rochester Medical CenterCredit: Unsplash/CC0 Public DomainNew research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy

Updated on:January 26,2024

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Updated on: January 26,2024

Study identifies factors associated with long-term use of FDA-approved anti-obesity medications

byCleveland ClinicPercentage of patients who were persistent with antiobesity medication (AOM) at early stage, medium term, and long term, by AOM agent. [Color figure can be viewed atwiley

Updated on:January 26,2024

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis

Updated on: March 28,2024

Study finds antibiotics combat gut bacteria that contribute to the pathogenesis of COVID-19

byWileyChest images of completely vaccinated sick moderate patients with SARS-CoV-2. Panel A-D: Four cases of vaccinated patients with pneumonia, no previous antibiotic use before hospital admis

Updated on:March 28,2024

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on: March 28,2024

Drug development advances in beneficial loss-of-function mutation targets validated by human genetics

by Sichuan International Medical Exchange and Promotion AssociationTargets primarily include PCSK9, ANGPTL3, HSD17B13, KHK, ASGR1, GPR75, CIDEB, and INHBE. Drug types primarily include small molecules

Updated on:March 28,2024

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on: April 28,2024

Researchers shed light on the molecular causes of different functions of opioid receptors

by Anne Grimm,Leipzig UniversityLigand-dependent activation of the µOR.a, Binding of agonist to the µOR activates two downstream signaling pathways: the G-protein pathway and the β-arresti

Updated on:April 28,2024

Treating tuberculosis when antibiotics no longer work

byUniversity of CologneCredit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2023.12.007Researchers have identified new antibiotic molecules that target Mycobacterium tuberculo

Updated on: January 26,2024

Treating tuberculosis when antibiotics no longer work

byUniversity of CologneCredit:Cell Chemical Biology(2024). DOI: 10.1016/j.chembiol.2023.12.007Researchers have identified new antibiotic molecules that target Mycobacterium tuberculo

Updated on:January 26,2024

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso

Updated on: March 11,2024

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)

New data shows prevalence of Premenstrual Dysphoric Disorder (PMDD)HEALTHMEDICAL SCIENCESMENTAL HEALTHRESEARCH29 January 2024Around 1.6% of women and girls have symptomatic Premenstrual Dysphoric Diso

Updated on:March 11,2024

Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended prog

Updated on: January 26,2024

Tucatinib plus trastuzumab emtansine may benefit patients with advanced or metastatic HER2-positive breast cancer

byAmerican Association for Cancer ResearchCredit: Unsplash/CC0 Public DomainA combination of two HER2-targeted drugs, tucatinib (Tukysa) and trastuzumab emtansine (Kadcyla, T-DM1), extended prog

Updated on:January 26,2024

Drug combo marks advance against bladder cancer

by Ernie MundellA cancer drug duo more than doubled the survival of people battling the most common form of advanced bladder cancer, trial results show.Patients who took a combo of meds called EV+P—

Updated on: March 20,2024

Drug combo marks advance against bladder cancer

by Ernie MundellA cancer drug duo more than doubled the survival of people battling the most common form of advanced bladder cancer, trial results show.Patients who took a combo of meds called EV+P—

Updated on:March 20,2024

Study finds new treatment makes patients with life-threatening muscle weakness stronger

byAarhus UniversityCredit: Unsplash/CC0 Public DomainFor the thousands of people globally affected by the disease myasthenia gravis (MG), everyday activities become a struggle, and in severe cas

Updated on: March 28,2024

Study finds new treatment makes patients with life-threatening muscle weakness stronger

byAarhus UniversityCredit: Unsplash/CC0 Public DomainFor the thousands of people globally affected by the disease myasthenia gravis (MG), everyday activities become a struggle, and in severe cas

Updated on:March 28,2024

Microbiome changes in chronic liver disease highlight need for personalized treatment

byKing's College LondonMicrobial diversity and community structure alterations by cirrhosis severity. Credit:Journal of Hepatology(2024). DOI: 10.1016/j.jhep.2024.09.046The bacte

Updated on: December 04,2024

Microbiome changes in chronic liver disease highlight need for personalized treatment

byKing's College LondonMicrobial diversity and community structure alterations by cirrhosis severity. Credit:Journal of Hepatology(2024). DOI: 10.1016/j.jhep.2024.09.046The bacte

Updated on:December 04,2024

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Updated on: January 26,2024

Five-day antibiotic course noninferior for pediatric febrile UTI

by Elana GotkineFor young children with febrile urinary tract infection (fUTI), a five-day amoxicillin-clavulanate course is noninferior to a 10-day course for recurrence of UTI within 30 days after c

Updated on:January 26,2024